Page last updated: 2024-10-23

azathioprine and Monosomy

azathioprine has been researched along with Monosomy in 2 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Monosomy: The condition in which one chromosome of a pair is missing. In a normally diploid cell it is represented symbolically as 2N-1.

Research Excerpts

ExcerptRelevanceReference
"We report 14 cases of secondary myelodysplastic syndromes (sMDS) following treatment with azathioprine for non-malignant disorders."7.73Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7. ( Gattermann, N; Germing, U; Haas, R; Hildebrandt, B; Knipp, S; Richter, J, 2005)
"We report 14 cases of secondary myelodysplastic syndromes (sMDS) following treatment with azathioprine for non-malignant disorders."3.73Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7. ( Gattermann, N; Germing, U; Haas, R; Hildebrandt, B; Knipp, S; Richter, J, 2005)
"We describe a case of spontaneously reversible refractory anaemia, a subtype of myelodysplastic syndrome (MDS), with monosomy 7 secondary to chronic treatment with azathioprine (AZA) in a young renal transplant recipient."3.69Spontaneous remission in a patient with therapy-related myelodysplastic syndrome (t-MDS) with monosomy 7. ( De Mulder, A; Ferster, A; Hansen, V; Heimann, P; Jannsen, F; Renneboog, B, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Knipp, S1
Hildebrandt, B1
Richter, J1
Haas, R1
Germing, U1
Gattermann, N1
Renneboog, B1
Hansen, V1
Heimann, P1
De Mulder, A1
Jannsen, F1
Ferster, A1

Other Studies

2 other studies available for azathioprine and Monosomy

ArticleYear
Secondary myelodysplastic syndromes following treatment with azathioprine are associated with aberrations of chromosome 7.
    Haematologica, 2005, Volume: 90, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Cell Transformation, Neoplastic;

2005
Spontaneous remission in a patient with therapy-related myelodysplastic syndrome (t-MDS) with monosomy 7.
    British journal of haematology, 1996, Volume: 92, Issue:3

    Topics: Adult; Anemia, Refractory; Azathioprine; Chromosomes, Human, Pair 7; Female; Humans; Immunosuppressi

1996