azathioprine has been researched along with Melanoma in 18 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 7.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| "We report two cases of stage IV malignant melanoma arising in patients treated with azathioprine for myasthenia gravis." | 3.76 | Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review. ( Collichio, F; Dillon, P; Sharpless, N; Thomas, N, 2010) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 3.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| " Malignant human melanoma cells can be transplanted in pretreated animals by contribution of the immunosuppression by means of Azathioprine." | 3.67 | [Xenogeneic transplantation of human malignant melanoma under high-dose immunosuppression]. ( Bittner, H; Gläser, A, 1984) |
| " However, the dosing and the duration of immunosuppressive therapy have not been systematically studied in the setting of treating ipilimumab-induced irAEs." | 2.52 | Ipilimumab-induced toxicities and the gastroenterologist. ( Bye, W; Cheng, R; Cooper, A; Kench, J; McNeil, C; Shackel, N; Watson, G, 2015) |
| "Anorectal malignant melanoma is often misdiagnosed as either hemorrhoids or benign anorectal conditions in inflammatory bowel disease." | 1.46 | Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis. ( Kim, SE; Moon, W; Park, MI; Park, SJ; Seo, KI, 2017) |
| "We report a case of disseminated superficial actinic porokeratosis (DSAP) with neutrophilic pustules within cornoid lamellae on histopathologic examination, corresponding to pustules along the elevated rim clinically as well." | 1.35 | Pustular porokeratosis. ( Miller, DD; Ruben, BS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Iwamoto, K | 1 |
| Ishitsuka, Y | 1 |
| Tanaka, R | 1 |
| Sekine, I | 1 |
| Fujimoto, M | 1 |
| Seo, KI | 1 |
| Moon, W | 1 |
| Kim, SE | 1 |
| Park, MI | 1 |
| Park, SJ | 1 |
| Huang, SZ | 1 |
| Liu, ZC | 1 |
| Liao, WX | 1 |
| Wei, JX | 1 |
| Huang, XW | 1 |
| Yang, C | 1 |
| Xia, YH | 1 |
| Li, L | 1 |
| Ye, C | 1 |
| Dai, SX | 1 |
| Gupta, A | 1 |
| Kuchana, SK | 1 |
| Guleria, S | 1 |
| Suri, D | 1 |
| Milosevic, Z | 1 |
| Tanic, N | 1 |
| Bankovic, J | 1 |
| Stankovic, T | 1 |
| Buta, M | 1 |
| Lavrnic, D | 1 |
| Milovanovic, Z | 1 |
| Pupic, G | 1 |
| Stojkovic, S | 1 |
| Milinkovic, V | 1 |
| Ito, Y | 1 |
| Dzodic, R | 1 |
| Rivinius, R | 1 |
| Helmschrott, M | 1 |
| Ruhparwar, A | 1 |
| Schmack, B | 1 |
| Klein, B | 1 |
| Erbel, C | 1 |
| Gleissner, CA | 1 |
| Akhavanpoor, M | 1 |
| Frankenstein, L | 1 |
| Darche, FF | 1 |
| Thomas, D | 1 |
| Ehlermann, P | 1 |
| Bruckner, T | 1 |
| Katus, HA | 1 |
| Doesch, AO | 1 |
| Cheng, R | 1 |
| Cooper, A | 1 |
| Kench, J | 1 |
| Watson, G | 1 |
| Bye, W | 1 |
| McNeil, C | 1 |
| Shackel, N | 1 |
| Miller, DD | 1 |
| Ruben, BS | 1 |
| Guenova, E | 1 |
| Lichte, V | 1 |
| Hoetzenecker, W | 1 |
| Woelbing, F | 1 |
| Moehrle, M | 1 |
| Roecken, M | 1 |
| Schaller, M | 1 |
| Dillon, P | 1 |
| Thomas, N | 1 |
| Sharpless, N | 1 |
| Collichio, F | 1 |
| Cuchural, GJ | 1 |
| Levey, AS | 1 |
| Pauker, SG | 1 |
| Bittner, H | 1 |
| Gläser, A | 1 |
| Spees, EK | 1 |
| Kramer, KK | 1 |
| Light, JA | 1 |
| Oakes, DD | 1 |
| Zimmerman, LE | 1 |
| Amato, MP | 1 |
| Pracucci, G | 1 |
| Ponziani, G | 1 |
| Siracusa, G | 1 |
| Fratiglioni, L | 1 |
| Amaducci, L | 1 |
| Szepietowski, J | 1 |
| Wasik, F | 1 |
| Szepietowski, T | 1 |
| Włodarczyk, M | 1 |
| Sobczak-Radwan, K | 1 |
| Czyz, W | 1 |
| Birkeland, SA | 1 |
| Kemp, E | 1 |
| Evans, DB | 1 |
| Calne, RY | 1 |
| Manny, N | 1 |
| Rosenman, E | 1 |
| Benbassat, J | 1 |
2 reviews available for azathioprine and Melanoma
| Article | Year |
|---|---|
Risk of skin cancers in thiopurines-treated and thiopurines-untreated patients with inflammatory bowel disease: A systematic review and meta-analysis.
Topics: Azathioprine; Databases, Bibliographic; Humans; Inflammatory Bowel Diseases; Melanoma; Mercaptopurin | 2019 |
Ipilimumab-induced toxicities and the gastroenterologist.
Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury | 2015 |
16 other studies available for azathioprine and Melanoma
| Article | Year |
|---|---|
Azathioprine combination therapy for steroid-refractory hepatic immune system-related adverse events.
Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Azathioprine; Chemical and Drug Induced Liver I | 2017 |
Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis.
Topics: Anus Neoplasms; Azathioprine; Colitis, Ulcerative; Colonoscopy; Female; Humans; Immunosuppressive Ag | 2017 |
Azathioprine-Induced Melanonychia.
Topics: Azathioprine; Humans; Melanoma; Nail Diseases | 2020 |
Genetic alterations in quadruple malignancies of a patient with multiple sclerosis: their role in malignancy development and response to therapy.
Topics: Adult; Azathioprine; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Medulla | 2014 |
Analysis of malignancies in patients after heart transplantation with subsequent immunosuppressive therapy.
Topics: Adult; Azathioprine; Cyclosporine; Female; Follow-Up Studies; Heart Transplantation; Humans; Immunos | 2015 |
Pustular porokeratosis.
Topics: Antimetabolites, Antineoplastic; Azathioprine; Colitis, Ulcerative; Diabetes Mellitus, Type 2; Human | 2009 |
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Topics: Aged; Antineoplastic Agents, Alkylating; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Ce | 2009 |
Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review.
Topics: Aged; Azathioprine; Head and Neck Neoplasms; Humans; Immunosuppression Therapy; Immunosuppressive Ag | 2010 |
Kidney failure or cancer. Should immunosuppression be continued in a transplant patient with malignant melanoma?
Topics: Adult; Azathioprine; Disease Susceptibility; Female; Glomerulonephritis; Graft Rejection; Humans; Im | 1984 |
[Xenogeneic transplantation of human malignant melanoma under high-dose immunosuppression].
Topics: Animals; Azathioprine; Humans; Immunosuppression Therapy; Male; Melanoma; Methotrexate; Neoplasm Tra | 1984 |
Reactivation of ocular malignant melanoma after renal transplantation.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Eye Neoplasms; Female; Humans; Immunosuppressive Agents; | 1980 |
Long-term safety of azathioprine therapy in multiple sclerosis.
Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci | 1993 |
Excess benign melanocytic naevi in renal transplant recipients.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Back; Buttocks; Case-Control Studies; Cyclosporine; F | 1997 |
Malignant tumours following immunosuppression in renal transplantation.
Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom | 1973 |
Renal transplantation in patients with carcinoma.
Topics: Adult; Angiography; Azathioprine; Cadaver; Female; Graft Rejection; Hematuria; Humans; Immunosuppres | 1974 |
Hazard of immunosuppressive therapy.
Topics: Adult; Azathioprine; Female; Humans; Lupus Erythematosus, Systemic; Melanoma; Prednisone | 1972 |