azathioprine has been researched along with Malignant Melanoma in 18 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 7.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| "We report two cases of stage IV malignant melanoma arising in patients treated with azathioprine for myasthenia gravis." | 3.76 | Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review. ( Collichio, F; Dillon, P; Sharpless, N; Thomas, N, 2010) |
| " A 67-year-old renal transplant recipient developed a nodular malignant melanoma after 30 years of immunosuppression with azathioprine and prednisolone." | 3.75 | Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine. ( Guenova, E; Hoetzenecker, W; Lichte, V; Moehrle, M; Roecken, M; Schaller, M; Woelbing, F, 2009) |
| " Malignant human melanoma cells can be transplanted in pretreated animals by contribution of the immunosuppression by means of Azathioprine." | 3.67 | [Xenogeneic transplantation of human malignant melanoma under high-dose immunosuppression]. ( Bittner, H; Gläser, A, 1984) |
| " However, the dosing and the duration of immunosuppressive therapy have not been systematically studied in the setting of treating ipilimumab-induced irAEs." | 2.52 | Ipilimumab-induced toxicities and the gastroenterologist. ( Bye, W; Cheng, R; Cooper, A; Kench, J; McNeil, C; Shackel, N; Watson, G, 2015) |
| "Anorectal malignant melanoma is often misdiagnosed as either hemorrhoids or benign anorectal conditions in inflammatory bowel disease." | 1.46 | Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis. ( Kim, SE; Moon, W; Park, MI; Park, SJ; Seo, KI, 2017) |
| "We report a case of disseminated superficial actinic porokeratosis (DSAP) with neutrophilic pustules within cornoid lamellae on histopathologic examination, corresponding to pustules along the elevated rim clinically as well." | 1.35 | Pustular porokeratosis. ( Miller, DD; Ruben, BS, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 2 (11.11) | 18.2507 |
| 2000's | 2 (11.11) | 29.6817 |
| 2010's | 7 (38.89) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Iwamoto, K | 1 |
| Ishitsuka, Y | 1 |
| Tanaka, R | 1 |
| Sekine, I | 1 |
| Fujimoto, M | 1 |
| Seo, KI | 1 |
| Moon, W | 1 |
| Kim, SE | 1 |
| Park, MI | 1 |
| Park, SJ | 1 |
| Huang, SZ | 1 |
| Liu, ZC | 1 |
| Liao, WX | 1 |
| Wei, JX | 1 |
| Huang, XW | 1 |
| Yang, C | 1 |
| Xia, YH | 1 |
| Li, L | 1 |
| Ye, C | 1 |
| Dai, SX | 1 |
| Gupta, A | 1 |
| Kuchana, SK | 1 |
| Guleria, S | 1 |
| Suri, D | 1 |
| Milosevic, Z | 1 |
| Tanic, N | 1 |
| Bankovic, J | 1 |
| Stankovic, T | 1 |
| Buta, M | 1 |
| Lavrnic, D | 1 |
| Milovanovic, Z | 1 |
| Pupic, G | 1 |
| Stojkovic, S | 1 |
| Milinkovic, V | 1 |
| Ito, Y | 1 |
| Dzodic, R | 1 |
| Rivinius, R | 1 |
| Helmschrott, M | 1 |
| Ruhparwar, A | 1 |
| Schmack, B | 1 |
| Klein, B | 1 |
| Erbel, C | 1 |
| Gleissner, CA | 1 |
| Akhavanpoor, M | 1 |
| Frankenstein, L | 1 |
| Darche, FF | 1 |
| Thomas, D | 1 |
| Ehlermann, P | 1 |
| Bruckner, T | 1 |
| Katus, HA | 1 |
| Doesch, AO | 1 |
| Cheng, R | 1 |
| Cooper, A | 1 |
| Kench, J | 1 |
| Watson, G | 1 |
| Bye, W | 1 |
| McNeil, C | 1 |
| Shackel, N | 1 |
| Miller, DD | 1 |
| Ruben, BS | 1 |
| Guenova, E | 1 |
| Lichte, V | 1 |
| Hoetzenecker, W | 1 |
| Woelbing, F | 1 |
| Moehrle, M | 1 |
| Roecken, M | 1 |
| Schaller, M | 1 |
| Dillon, P | 1 |
| Thomas, N | 1 |
| Sharpless, N | 1 |
| Collichio, F | 1 |
| Cuchural, GJ | 1 |
| Levey, AS | 1 |
| Pauker, SG | 1 |
| Bittner, H | 1 |
| Gläser, A | 1 |
| Spees, EK | 1 |
| Kramer, KK | 1 |
| Light, JA | 1 |
| Oakes, DD | 1 |
| Zimmerman, LE | 1 |
| Amato, MP | 1 |
| Pracucci, G | 1 |
| Ponziani, G | 1 |
| Siracusa, G | 1 |
| Fratiglioni, L | 1 |
| Amaducci, L | 1 |
| Szepietowski, J | 1 |
| Wasik, F | 1 |
| Szepietowski, T | 1 |
| Włodarczyk, M | 1 |
| Sobczak-Radwan, K | 1 |
| Czyz, W | 1 |
| Birkeland, SA | 1 |
| Kemp, E | 1 |
| Evans, DB | 1 |
| Calne, RY | 1 |
| Manny, N | 1 |
| Rosenman, E | 1 |
| Benbassat, J | 1 |
2 reviews available for azathioprine and Malignant Melanoma
| Article | Year |
|---|---|
Risk of skin cancers in thiopurines-treated and thiopurines-untreated patients with inflammatory bowel disease: A systematic review and meta-analysis.
Topics: Azathioprine; Databases, Bibliographic; Humans; Inflammatory Bowel Diseases; Melanoma; Mercaptopurin | 2019 |
Ipilimumab-induced toxicities and the gastroenterologist.
Topics: Antibodies, Monoclonal; Azathioprine; Calcineurin Inhibitors; Chemical and Drug Induced Liver Injury | 2015 |
16 other studies available for azathioprine and Malignant Melanoma
| Article | Year |
|---|---|
Azathioprine combination therapy for steroid-refractory hepatic immune system-related adverse events.
Topics: Aged; Antibodies, Monoclonal; Antineoplastic Agents; Azathioprine; Chemical and Drug Induced Liver I | 2017 |
Malignant Melanoma of the Anus Found during Routine Colonoscopy in Ulcerative Colitis.
Topics: Anus Neoplasms; Azathioprine; Colitis, Ulcerative; Colonoscopy; Female; Humans; Immunosuppressive Ag | 2017 |
Azathioprine-Induced Melanonychia.
Topics: Azathioprine; Humans; Melanoma; Nail Diseases | 2020 |
Genetic alterations in quadruple malignancies of a patient with multiple sclerosis: their role in malignancy development and response to therapy.
Topics: Adult; Azathioprine; Bone Neoplasms; Breast Neoplasms; Carcinoma, Ductal, Breast; Carcinoma, Medulla | 2014 |
Analysis of malignancies in patients after heart transplantation with subsequent immunosuppressive therapy.
Topics: Adult; Azathioprine; Cyclosporine; Female; Follow-Up Studies; Heart Transplantation; Humans; Immunos | 2015 |
Pustular porokeratosis.
Topics: Antimetabolites, Antineoplastic; Azathioprine; Colitis, Ulcerative; Diabetes Mellitus, Type 2; Human | 2009 |
Nodular malignant melanoma and multiple cutaneous neoplasms under immunosuppression with azathioprine.
Topics: Aged; Antineoplastic Agents, Alkylating; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Ce | 2009 |
Regression of advanced melanoma upon withdrawal of immunosuppression: case series and literature review.
Topics: Aged; Azathioprine; Head and Neck Neoplasms; Humans; Immunosuppression Therapy; Immunosuppressive Ag | 2010 |
Kidney failure or cancer. Should immunosuppression be continued in a transplant patient with malignant melanoma?
Topics: Adult; Azathioprine; Disease Susceptibility; Female; Glomerulonephritis; Graft Rejection; Humans; Im | 1984 |
[Xenogeneic transplantation of human malignant melanoma under high-dose immunosuppression].
Topics: Animals; Azathioprine; Humans; Immunosuppression Therapy; Male; Melanoma; Methotrexate; Neoplasm Tra | 1984 |
Reactivation of ocular malignant melanoma after renal transplantation.
Topics: Adult; Antilymphocyte Serum; Azathioprine; Eye Neoplasms; Female; Humans; Immunosuppressive Agents; | 1980 |
Long-term safety of azathioprine therapy in multiple sclerosis.
Topics: Adenocarcinoma; Adult; Aged; Azathioprine; Breast Neoplasms; Carcinoma in Situ; Female; Humans; Inci | 1993 |
Excess benign melanocytic naevi in renal transplant recipients.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Back; Buttocks; Case-Control Studies; Cyclosporine; F | 1997 |
Malignant tumours following immunosuppression in renal transplantation.
Topics: Adenocarcinoma; Adult; Azathioprine; Brain Neoplasms; Carcinoma; Carcinoma, Hepatocellular; Carcinom | 1973 |
Renal transplantation in patients with carcinoma.
Topics: Adult; Angiography; Azathioprine; Cadaver; Female; Graft Rejection; Hematuria; Humans; Immunosuppres | 1974 |
Hazard of immunosuppressive therapy.
Topics: Adult; Azathioprine; Female; Humans; Lupus Erythematosus, Systemic; Melanoma; Prednisone | 1972 |