Page last updated: 2024-10-23

azathioprine and Malacoplakia

azathioprine has been researched along with Malacoplakia in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Malacoplakia: The formation of soft patches on the mucous membrane of a hollow organ, such as the urogenital tract or digestive tract.

Research Excerpts

ExcerptRelevanceReference
"Pemphigus vulgaris is an uncommon auto-immune disease which responds well to treatment with corticosteroids and azathioprine."3.68Immunosuppressive therapy for pemphigus vulgaris complicated by malakoplakia of the bladder. ( Allen, FJ; Heyns, CF; Jordaan, HF; Schneider, J, 1990)
"We review the pathogenesis of malakoplakia and report a novel form of treatment successfully used in an 8-week-old infant with bilateral renal malakoplakia."2.38Renal parenchymal malakoplakia--a case report and review of the literature. ( Milford, DV; Raafat, F; Saleem, MA; White, RH, 1993)
"Studies of 4 patients with malakoplakia--2 renal transplant recipients, 1 patient with systemic lupus erythematosus, and 1 patient with polymyositis--are reported."1.27Malakoplakia and immunosuppressive therapy. Reversal of clinical and leukocyte abnormalities after withdrawal of prednisone and azathioprine. ( Bear, RA; Biggar, WD; Cardella, C; Crawford, L; Gladman, D; Reynolds, WJ, 1985)
"The etiology of malakoplakia should be identified for each patient if appropriate treatment is to be given."1.26Malakoplakia: evidence for an acquired disease secondary to immunosuppression. ( Bear, RA; Biggar, WD; Keating, A, 1981)
"A case of malakoplakia affecting the entire urinary tract is described."1.26Corynebacterium hofmannii infection after renal transplantation. ( Aubrey, C; Bewick, M; Cameron, JS; Nathan, AW; Ogg, CS; Turner, DR; Williams, DG, 1982)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19904 (50.00)18.7374
1990's4 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Streem, SB1
Biggar, WD2
Keating, A1
Bear, RA2
Nathan, AW1
Turner, DR1
Aubrey, C1
Cameron, JS1
Williams, DG1
Ogg, CS1
Bewick, M1
Saleem, MA1
Milford, DV1
Raafat, F1
White, RH1
McKenzie, KJ1
More, IA1
Ourahma, S1
Barrou, B1
Bitker, MO1
Sylla, C1
Mouquet, C1
Chatelain, C1
Jordaan, HF1
Heyns, CF1
Allen, FJ1
Schneider, J1
Crawford, L1
Cardella, C1
Gladman, D1
Reynolds, WJ1

Reviews

1 review available for azathioprine and Malacoplakia

ArticleYear
Renal parenchymal malakoplakia--a case report and review of the literature.
    Pediatric nephrology (Berlin, Germany), 1993, Volume: 7, Issue:3

    Topics: Azathioprine; Escherichia coli Infections; Female; Humans; Hypertrophy; Infant; Malacoplakia; Nephri

1993

Other Studies

7 other studies available for azathioprine and Malacoplakia

ArticleYear
Genitourinary malacoplakia in renal transplant recipients: pathogenic, prognostic and therapeutic considerations.
    The Journal of urology, 1984, Volume: 132, Issue:1

    Topics: Adult; Anti-Infective Agents, Urinary; Azathioprine; Biopsy; Drug Combinations; Female; Humans; Immu

1984
Malakoplakia: evidence for an acquired disease secondary to immunosuppression.
    Transplantation, 1981, Volume: 31, Issue:2

    Topics: Adult; Azathioprine; Blood Bactericidal Activity; Escherichia coli Infections; Humans; Immunosuppres

1981
Corynebacterium hofmannii infection after renal transplantation.
    Clinical nephrology, 1982, Volume: 17, Issue:6

    Topics: Adult; Azathioprine; Corynebacterium Infections; Female; Graft Rejection; Humans; Immunosuppression

1982
Non-progressive malakoplakia in a live donor renal allograft.
    Histopathology, 1996, Volume: 28, Issue:3

    Topics: Adult; Azathioprine; Female; Glomerulonephritis; Graft Survival; Humans; Kidney Failure, Chronic; Ki

1996
Rectal malacoplakia in a renal transplant recipient.
    Transplantation proceedings, 1996, Volume: 28, Issue:5

    Topics: Azathioprine; Creatinine; Follow-Up Studies; Humans; Immunosuppressive Agents; Kidney Transplantatio

1996
Immunosuppressive therapy for pemphigus vulgaris complicated by malakoplakia of the bladder.
    Clinical and experimental dermatology, 1990, Volume: 15, Issue:6

    Topics: Aged; Azathioprine; Escherichia coli Infections; Female; Humans; Immunosuppression Therapy; Malacopl

1990
Malakoplakia and immunosuppressive therapy. Reversal of clinical and leukocyte abnormalities after withdrawal of prednisone and azathioprine.
    The American journal of pathology, 1985, Volume: 119, Issue:1

    Topics: Abscess; Adult; Azathioprine; Carbachol; Escherichia coli Infections; Female; Humans; Kidney Transpl

1985