azathioprine has been researched along with Macular Edema in 6 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Macular Edema: Fluid accumulation in the outer layer of the MACULA LUTEA that results from intraocular or systemic insults. It may develop in a diffuse pattern where the macula appears thickened or it may acquire the characteristic petaloid appearance referred to as cystoid macular edema. Although macular edema may be associated with various underlying conditions, it is most commonly seen following intraocular surgery, venous occlusive disease, DIABETIC RETINOPATHY, and posterior segment inflammatory disease. (From Survey of Ophthalmology 2004; 49(5) 470-90)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Methotrexate is probably slightly more efficacious than mycophenolate in achieving control of inflammation, including steroid-sparing control (moderate-certainty evidence), although there was insufficient evidence to prefer one medication over the other in the VKH subgroup (very low-certainty evidence)." | 5.22 | Non-biologic, steroid-sparing therapies for non-infectious intermediate, posterior, and panuveitis in adults. ( Edwards Mayhew, RG; Leslie, L; Li, T; McCann, P; Palestine, AG; Strong Caldwell, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Edwards Mayhew, RG | 1 |
| Li, T | 1 |
| McCann, P | 1 |
| Leslie, L | 1 |
| Strong Caldwell, A | 1 |
| Palestine, AG | 1 |
| Corduneanu, A | 1 |
| Sevciuc, R | 1 |
| Gherasim, V | 1 |
| Liu, X | 1 |
| Zhang, M | 1 |
| Ferreyra, HA | 1 |
| Jayasundera, T | 1 |
| Khan, NW | 1 |
| He, S | 1 |
| Lu, Y | 1 |
| Heckenlively, JR | 1 |
| Sreekantam, S | 1 |
| Denniston, AK | 1 |
| Murray, PI | 1 |
| Bentley, CR | 1 |
| Stanford, MR | 1 |
| Shilling, JS | 1 |
| Sanders, MD | 1 |
| Graham, EM | 1 |
1 review available for azathioprine and Macular Edema
| Article | Year |
|---|---|
Non-biologic, steroid-sparing therapies for non-infectious intermediate, posterior, and panuveitis in adults.
Topics: Adult; Antirheumatic Agents; Azathioprine; Cyclosporine; Humans; Immunosuppressive Agents; Inflammat | 2022 |
5 other studies available for azathioprine and Macular Edema
| Article | Year |
|---|---|
[Behcet disease -- case report].
Topics: Adult; Azathioprine; Behcet Syndrome; Cyclosporine; Drug Therapy, Combination; Erythema Nodosum; Fem | 2012 |
[Uveitic macular edema and the pharmacotherapy].
Topics: Acetazolamide; Adrenal Cortex Hormones; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; | 2015 |
Management of autoimmune retinopathies with immunosuppression.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Autoantibodies; Autoantigens; Autoimmune Diseases; Azath | 2009 |
Survey of expert practice and perceptions of the supporting clinical evidence for the management of uveitis-related cataract and cystoid macular oedema.
Topics: Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Azathioprine; Cataract; Cataract Extraction; | 2011 |
Macular ischaemia in posterior uveitis.
Topics: Adult; Azathioprine; Cyclosporine; Female; Fluorescein Angiography; Humans; Immunosuppressive Agents | 1993 |