Page last updated: 2024-10-23

azathioprine and Lymphoma

azathioprine has been researched along with Lymphoma in 91 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Lymphoma: A general term for various neoplastic diseases of the lymphoid tissue.

Research Excerpts

ExcerptRelevanceReference
"We searched MEDLINE, EMBASE, and Cochrane databases, as well as conference abstracts and international publications, for the terms "6-MP and lymphoma," "6-mercaptopurine and lymphoma," "thiopurines and lymphoma," "azathioprine and cancer and IBD," "azathioprine and malignancy and IBD," "azathioprine and lymphoma," and "lymphoproliferative and thiopurines."8.91Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis. ( Beaugerie, L; Beigel, F; Bewtra, M; Biancone, L; Blonski, WC; Brensinger, CM; Chaparro, M; Gisbert, JP; Kotlyar, DS; Lewis, JD; Lichtenstein, GR; Loftus, EV; Peyrin-Biroulet, L; Sandilya, S; Tierney, A; Van Domselaar, M, 2015)
"The purpose of this meta-analysis was to provide a more precise estimate of the relative risk of lymphoma among IBD patients treated with azathioprine or 6-MP."8.82Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. ( Brensinger, C; Fraser, AG; Kandiel, A; Korelitz, BI; Lewis, JD, 2005)
" Prolonged treatment with immunosuppressants including azathioprine (Aza), a thiopurine prodrug, has been suggested as a risk factor for the development of late onset leukemias/lymphomas displaying a microsatellite instability (MSI) phenotype, the hallmark of a defective MMR system."7.81Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model. ( Beaugerie, L; Bodo, S; Brousse, N; Buhard, O; Capel, C; Chalastanis, A; Collura, A; Cuillières-Dartigues, P; Dinard, L; Dumont, S; Duval, A; Fabiani, B; Fléjou, JF; Lafitte, P; Ledent, T; Muleris, M; Penard-Lacronique, V; Sourrouille, I; Svrcek, M; Wanherdrick, K, 2015)
"Prospective follow-up for a median of 35 months of a French cohort of 19 486 patients with inflammatory bowel disease showed a nearly 4-fold increase in the risk of lymphoma in patients exposed to azathioprine or mercaptopurine (relative risk 3."7.77Azathioprine and mercaptopurine: lymphoma. ( , 2011)
"Treatment of inflammatory bowel disease with azathioprine or 6-mercaptopurine appears to be associated with a small increased risk of Epstein-Barr virus-positive lymphoma."7.71Epstein-Barr virus-positive lymphoma in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine. ( Burgart, LJ; Dayharsh, GA; Loftus, EV; Macon, WR; Sandborn, WJ; Tremaine, WJ; Witzig, TE; Zinsmeister, AR, 2002)
"Two hundred and two patients with rheumatoid arthritis (RA) starting treatment with large doses of azathioprine (median 300 mg/day) between 1964 and 1974 were followed up until March 1984."7.67Lymphoproliferative cancer and other malignancy in patients with rheumatoid arthritis treated with azathioprine: a 20 year follow up study. ( Evans, SJ; Hazleman, B; Petrie, J; Silman, AJ, 1988)
"Many of these lymphomas are associated with Epstein-Barr virus (EBV), which might be reactivated under immunosuppression."5.48Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis
. ( Birkmann, J; Holzgrabe, U; Munz, M; Pretscher, D; Sörgel, F; Wilhelm, M, 2018)
" It discusses the company's epidemiologic approach to the question of association between treatment with disease-modifying antirheumatic drugs, one of which is manufactured by Burroughs Wellcome Company (Imuran brand azathioprine) and a possible increased risk of neoplasms in patients receiving these drugs as treatment for their rheumatoid arthritis."5.05Pharmaco-epidemiology--drugs, arthritis, and neoplasms: industry contribution to the data. ( Tilson, HH; Whisnant, J, 1985)
"We searched MEDLINE, EMBASE, and Cochrane databases, as well as conference abstracts and international publications, for the terms "6-MP and lymphoma," "6-mercaptopurine and lymphoma," "thiopurines and lymphoma," "azathioprine and cancer and IBD," "azathioprine and malignancy and IBD," "azathioprine and lymphoma," and "lymphoproliferative and thiopurines."4.91Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis. ( Beaugerie, L; Beigel, F; Bewtra, M; Biancone, L; Blonski, WC; Brensinger, CM; Chaparro, M; Gisbert, JP; Kotlyar, DS; Lewis, JD; Lichtenstein, GR; Loftus, EV; Peyrin-Biroulet, L; Sandilya, S; Tierney, A; Van Domselaar, M, 2015)
"The purpose of this meta-analysis was to provide a more precise estimate of the relative risk of lymphoma among IBD patients treated with azathioprine or 6-MP."4.82Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. ( Brensinger, C; Fraser, AG; Kandiel, A; Korelitz, BI; Lewis, JD, 2005)
" We present what we believe to be the first case of primary esophageal lymphoma in a patient on long-term immunosuppression with azathioprine who was also infected with the hepatitis C virus (HCV)."4.81Primary lymphoma of the esophagus in a chronically immunosuppressed patient with hepatitis C infection: case report and review of the literature. ( Golioto, M; McGrath, K, 2001)
" Prolonged treatment with immunosuppressants including azathioprine (Aza), a thiopurine prodrug, has been suggested as a risk factor for the development of late onset leukemias/lymphomas displaying a microsatellite instability (MSI) phenotype, the hallmark of a defective MMR system."3.81Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model. ( Beaugerie, L; Bodo, S; Brousse, N; Buhard, O; Capel, C; Chalastanis, A; Collura, A; Cuillières-Dartigues, P; Dinard, L; Dumont, S; Duval, A; Fabiani, B; Fléjou, JF; Lafitte, P; Ledent, T; Muleris, M; Penard-Lacronique, V; Sourrouille, I; Svrcek, M; Wanherdrick, K, 2015)
"Prospective follow-up for a median of 35 months of a French cohort of 19 486 patients with inflammatory bowel disease showed a nearly 4-fold increase in the risk of lymphoma in patients exposed to azathioprine or mercaptopurine (relative risk 3."3.77Azathioprine and mercaptopurine: lymphoma. ( , 2011)
"Most untreated Msh2(WT) and Msh2(+/)⁻ mice remained asymptomatic and alive at 250 days of age, whereas azathioprine-treated Msh2(WT) and Msh2(+/)⁻ mice developed lymphomas and died prematurely (median survival of 71 and 165 days of age, respectively)."3.76Azathioprine-induced carcinogenesis in mice according to Msh2 genotype. ( Antoine, N; Buhard, O; Chalastanis, A; Defaweux, V; Dumont, S; Duval, A; Fabiani, B; Fléjou, JF; Muleris, M; Penard-Lacronique, V; Renault, I; Svrcek, M; Te Riele, H; Tubacher, E, 2010)
"Treatment of inflammatory bowel disease with azathioprine or 6-mercaptopurine appears to be associated with a small increased risk of Epstein-Barr virus-positive lymphoma."3.71Epstein-Barr virus-positive lymphoma in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine. ( Burgart, LJ; Dayharsh, GA; Loftus, EV; Macon, WR; Sandborn, WJ; Tremaine, WJ; Witzig, TE; Zinsmeister, AR, 2002)
"A prospective study in the United Kingdom of 1,634 patients without transplants treated with immunosuppressive drugs (68 percent with azathioprine, 28 percent with cyclophosphamide) found an excess of non-Hodgkin's lymphoma and squamous cell skin cancer, suggesting that the excesses (although larger) of the same malignancies found among transplant recipients are not due solely to the foreign antigens of the graft."3.67Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment. ( Kinlen, LJ, 1985)
"Two hundred and two patients with rheumatoid arthritis (RA) starting treatment with large doses of azathioprine (median 300 mg/day) between 1964 and 1974 were followed up until March 1984."3.67Lymphoproliferative cancer and other malignancy in patients with rheumatoid arthritis treated with azathioprine: a 20 year follow up study. ( Evans, SJ; Hazleman, B; Petrie, J; Silman, AJ, 1988)
"A woman, aged 58, who had undergone prolonged treatment with corticosteroids for generalized necrotizing vasculitis, and had received azathioprine (Imurel) for 18 months, 4 years after discontinuing the latter treatment, developed peripheral neuropathy and a rapidly progressing cerebral disorder suggesting a basal meningeal process."3.66Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression. ( Jellinger, K; Kothbauer, P; Sunder-Plassmann, E; Weiss, R, 1979)
"Whether the risk of lymphoma is increased by immunosuppressive treatment with azathioprine, 6-mercaptopurine or infliximab is a common concern among patients and physicians considering using these agents."2.41Review article: the risk of lymphoma associated with inflammatory bowel disease and immunosuppressive treatment. ( Aithal, GP; Mansfield, JC, 2001)
"Many of these lymphomas are associated with Epstein-Barr virus (EBV), which might be reactivated under immunosuppression."1.48Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis
. ( Birkmann, J; Holzgrabe, U; Munz, M; Pretscher, D; Sörgel, F; Wilhelm, M, 2018)
"We present a case of atypical idiopathic retroperitoneal fibrosis (iRPF) presenting as a large pelvic tumor, for which it proved difficult to exclude T-cell malignant lymphoma."1.37Idiopathic retroperitoneal fibrosis mimicking malignant lymphoma. ( de Mol, M; Langerak, AW; van Bommel, EF; Westenend, PJ, 2011)
"The age-adjusted 8-year incidence of malignant lymphoma in the Netherlands was retrieved from the Central Bureau of Statistics."1.37Risk of malignant lymphoma in patients with inflammatory bowel diseases: a Dutch nationwide study. ( Bakkal, N; Casparie, MK; de Jong, DJ; Dijkstra, G; Hommes, DW; Minnee, RC; Oldenburg, B; Pierik, M; Stokkers, P; van Bodegraven, AA; van der Woude, CJ; Vos, AC, 2011)
"Azathioprine is an accepted treatment of inflammatory bowel disease (IBD), but concerns exist regarding its carcinogenic potential."1.36Risk of cancer in inflammatory bowel disease treated with azathioprine: a UK population-based case-control study. ( Armstrong, RG; Card, TR; West, J, 2010)
"Rather for several types of cancer a significantly reduced risk was observed, except for breast cancer in women treated with IS."1.35Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis. ( Berthier, F; Clavelou, P; Danzon, A; de Seze, J; Debouverie, M; Defer, G; Gout, O; Lebrun, C; Rumbach, L; Vermersch, P; Wiertlevski, S, 2008)
"Azathioprine was given to 626 of 2204 patients (855 with Crohn's disease and 1349 with ulcerative colitis)."1.31Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine. ( Fraser, AG; Jewell, DP; Orchard, TR; Robinson, EM, 2002)
" After our early experience with group 1, we attempted to use a lower cyclosporine dosage in group 2."1.29Heart transplantation for chronic Chagas' heart disease. ( Amato-Neto, V; Bacal, F; Bellotti, G; Bocchi, EA; Fiorelli, A; Higuchi, ML; Jatene, AD; Mocelin, AO; Pileggi, F; Stolf, NA; Uip, D, 1996)
"Because of the increased incidence of malignant lymphoma under cyclosporin A this drug should be held in reserve in the treatment of Crohn's disease, until results from controlled studies have become available."1.27[Crohn disease: initial experiences with cyclosporin A in an adolescent girl]. ( Dannecker, G; Malchow, H; Niessen, KH; Ranke, MB, 1985)
"The incidence of malignant neoplasms in patients subjected to pharmacological immunosuppression following kidney transplantation is higher than that observed in the control population at large."1.27[Malignant neoplastic pathology in patients given a kidney transplant]. ( Boschiero, L; Dean, P; Faccincani, L; Muolo, A; Prati, GF; Recchia, G, 1987)
"Data on the possible increased risk of malignancy in rheumatoid arthritis are still being collected, and until further information is available, the use of immunosuppressive drugs, particularly alkylating agents, in the treatment of rheumatoid arthritis should be reserved for patients with severe progressive disease or life-threatening complications."1.27Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens. ( Hazleman, B, 1985)
"They included 8 cases of malignant lymphoma (non-Hodgkin), one of subacute myeloic leukemia, one of acute lymphatic leukemia, 6 skin cancers and 9 cancers of internal organs."1.26[Malignant tumors in bearers of kidney grafts in immunosuppressive therapy]. ( Binswanger, U; Briner, J; Largiadèr, F; Uhlschmid, G; Vollenweider, A, 1982)
" The correlation between these is poor, in many patients, at the dosage used in man."1.26The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens. ( Hazleman, BL, 1982)
"Azathioprine was best tolerated, but gave only medium results whereas procarbazine, as a very potent drug, had the highest rate of side effects (especially depression of bone marrow, infections, gastrointestinal manifestations etc."1.25[Side effects in immunosuppressive therapy]. ( Thumb, N, 1975)

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-199044 (48.35)18.7374
1990's11 (12.09)18.2507
2000's14 (15.38)29.6817
2010's20 (21.98)24.3611
2020's2 (2.20)2.80

Authors

AuthorsStudies
Kobayashi, T1
Udagawa, E1
Hibi, T1
Ranjan, MK1
Kante, B1
Vuyyuru, SK1
Kumar, P1
Mundhra, SK1
Golla, R1
Sharma, R1
Sahni, P1
Das, P1
Makharia, G1
Kedia, S1
Ahuja, V1
Lemaitre, M1
Kirchgesner, J1
Rudnichi, A1
Carrat, F1
Zureik, M1
Carbonnel, F1
Dray-Spira, R1
Munz, M1
Pretscher, D1
Wilhelm, M1
Holzgrabe, U1
Sörgel, F1
Birkmann, J1
Jordan, B1
Zierz, S1
Weber, T1
Jordan, K1
Khan, N2
Abbas, AM2
Lichtenstein, GR2
Loftus, EV4
Bazzano, LA2
Beaugerie, L3
Kumar, AR1
Dudnick, RS1
Kotlyar, DS1
Lewis, JD4
Tierney, A1
Brensinger, CM1
Gisbert, JP1
Peyrin-Biroulet, L1
Blonski, WC1
Van Domselaar, M1
Chaparro, M1
Sandilya, S1
Bewtra, M2
Beigel, F1
Biancone, L1
Scott, FI1
Vajravelu, RK1
Mamtani, R1
Lee, D1
Goldberg, DS1
Bodo, S1
Svrcek, M2
Sourrouille, I1
Cuillières-Dartigues, P1
Ledent, T1
Dumont, S2
Dinard, L1
Lafitte, P1
Capel, C1
Collura, A1
Buhard, O2
Wanherdrick, K1
Chalastanis, A2
Penard-Lacronique, V2
Fabiani, B2
Fléjou, JF2
Brousse, N1
Duval, A2
Muleris, M2
Pourfarziani, V1
Taheri, S1
Lessan-Pezeshki, M1
Nourbala, MH1
Simforoosh, N1
Nemati, E1
Makhdoomi, K1
Ghafari, A1
Ahmadpour, P1
Nafar, M1
Einollahi, B1
Armstrong, RG1
West, J1
Card, TR1
Defaweux, V1
Antoine, N1
Renault, I1
Tubacher, E1
Te Riele, H1
Loganathan, S1
Zaitoun, A1
Charlton, CP1
Vos, AC1
Bakkal, N1
Minnee, RC1
Casparie, MK1
de Jong, DJ1
Dijkstra, G1
Stokkers, P1
van Bodegraven, AA1
Pierik, M1
van der Woude, CJ1
Oldenburg, B1
Hommes, DW1
van Bommel, EF1
de Mol, M1
Langerak, AW1
Westenend, PJ1
Herrinton, LJ1
Liu, L1
Weng, X1
Hutfless, S1
Allison, JE1
Sultan, K1
Korelitz, BI2
Present, D1
Katz, S1
Sunday, S1
Shapira, I1
Kaukinen, K1
Ilus, T1
Vornanen, M1
Collin, P1
Subramaniam, K1
D'Rozario, J1
Pavli, P1
Fraser, AG2
Orchard, TR1
Robinson, EM1
Jewell, DP2
McGovern, DP1
Kandiel, A1
Brensinger, C1
Finelli, PF1
Sondheimer, JM1
Ang, YS1
Farrell, RJ1
Lin, PC1
Hsiao, LT1
Chen, PM1
Jones, JL1
Lebrun, C1
Debouverie, M1
Vermersch, P1
Clavelou, P1
Rumbach, L1
de Seze, J1
Wiertlevski, S1
Defer, G1
Gout, O1
Berthier, F1
Danzon, A1
Crawford, DH1
Edwards, JM1
Sweny, P1
Hoffbrand, AV1
Janossy, G1
Sato, A1
Kobayashi, K1
Okabe, H1
Fukuda, S1
Cohen, DJ1
Loertscher, R1
Rubin, MF1
Tilney, NL1
Carpenter, CB1
Strom, TB1
Chanda, JJ1
Callen, JP1
Cohen, SM1
Erturk, E1
Skibba, JL1
Bryan, GT1
Geary, CG1
Vollenweider, A1
Largiadèr, F1
Uhlschmid, G1
Binswanger, U1
Briner, J1
Hazleman, BL1
Lloveras, JJ1
Cointault, O1
Huyn, A1
Boyer, M1
Fournial, G1
Rostaing, L1
Durand, D1
Suc, JM1
Chu, SH1
Lai, MK1
Huang, CC1
Chuang, CK1
Chen, HW1
Chen, CS1
Batiuk, TD1
Barry, JM1
Bennett, WM1
Meyer, MM1
Tolzman, D1
Norman, DJ1
Present, DH1
Luciani, J1
Benalia, H1
Bitker, MO1
Mouquet, C1
Chartier-Kastler, E1
Ourhama, S1
Jacobs, C1
Chatelain, C1
Viars, P1
Penn, I3
Bocchi, EA1
Bellotti, G1
Mocelin, AO1
Uip, D1
Bacal, F1
Higuchi, ML1
Amato-Neto, V1
Fiorelli, A1
Stolf, NA1
Jatene, AD1
Pileggi, F1
Gruessner, RW1
Niaudet, P1
Herrlinger, U1
Weller, M1
Dichgans, J1
Melms, A1
Golioto, M1
McGrath, K1
Aithal, GP1
Mansfield, JC1
Dayharsh, GA1
Sandborn, WJ1
Tremaine, WJ1
Zinsmeister, AR1
Witzig, TE1
Macon, WR1
Burgart, LJ1
Jellinger, K1
Kothbauer, P1
Weiss, R1
Sunder-Plassmann, E1
Wurm, K1
Sieber, SM1
Kinlen, LJ2
Sheil, AG1
Peto, J1
Doll, R1
Mitrou, PS1
Fischer, M1
Mitrou, G1
Röttger, P1
Jauregui, HO1
Krueger, G1
Zółtowska, A1
Maniszewska, B1
Thumb, N1
Emery, RW1
Graif, JL1
Hale, K1
Eales, F1
Von Rueden, TJ1
Pritzker, MR1
Love, K1
Arom, KV1
Urowitz, MB1
Lee, P1
Ito, A1
Mori, M1
Naito, M1
Smith, JL1
Wilkinson, AH1
Hunsicker, LG1
Tobacman, J1
Kapelanski, DP1
Johnson, M1
Wright, FH1
Behrendt, DM1
Corry, RJ1
Dannecker, G1
Malchow, H1
Niessen, KH1
Ranke, MB1
Silman, AJ1
Petrie, J1
Hazleman, B2
Evans, SJ1
Polson, RJ1
Neuberger, J1
Forman, D1
Calne, R1
Williams, R1
Prati, GF1
Recchia, G1
Dean, P1
Boschiero, L1
Faccincani, L1
Muolo, A1
Citterio, F1
Lauriola, L1
Nanni, G1
Vecchio, FM1
Magalini, SC1
Castagneto, M1
Tilson, HH1
Whisnant, J1
Krueger, TC1
Tallent, MB1
Richie, RE1
Johnson, HK1
MacDonell, RC1
Turner, B1
Lovisetto, P1
Manachino, D1
Biarese, V1
Marchi, L1
Andrione, P1
Schneck, SA2
Gleichmann, E2
Gleichmann, H2
Casey, TP2
Mellors, RC1
Rhodes, J1
Imamura, N1
Nakano, M1
Kawase, A1
Kawamura, Y1
Yokoro, K1
Cerilli, J1
Hattan, D1
Hammond, W1
Brettschneider, L1
Starzl, TE1
Swannell, AJ1
Kersley, GD1
Vredevoe, DL1
Hays, EF1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study of Compliance, Practice Patterns, and Barriers REgarding Established National Screening Programs for Barrett's Esophagus: SCREEN-BE[NCT04408105]725 participants (Actual)Observational2020-02-19Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

16 reviews available for azathioprine and Lymphoma

ArticleYear
Risk of lymphoma in patients with inflammatory bowel disease treated with azathioprine and 6-mercaptopurine: a meta-analysis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2015, Volume: 13, Issue:5

    Topics: Adult; Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Ly

2015
[When gluten-free diet does not cure celiac disease].
    Duodecim; laaketieteellinen aikakauskirja, 2012, Volume: 128, Issue:9

    Topics: Adrenal Cortex Hormones; Antimetabolites, Antineoplastic; Azathioprine; Biomarkers; Celiac Disease;

2012
Lymphoma and other lymphoproliferative disorders in inflammatory bowel disease: a review.
    Journal of gastroenterology and hepatology, 2013, Volume: 28, Issue:1

    Topics: Age Factors; Azathioprine; Epstein-Barr Virus Infections; Humans; Immunosuppressive Agents; Inflamma

2013
Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine.
    Gut, 2005, Volume: 54, Issue:8

    Topics: Azathioprine; Female; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lymphoma; Male;

2005
Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment?
    Inflammatory bowel diseases, 2007, Volume: 13, Issue:10

    Topics: Anti-Infective Agents; Antibodies, Monoclonal; Azathioprine; Humans; Immunosuppressive Agents; Infla

2007
Cyclosporine: a new immunosuppressive agent for organ transplantation.
    Annals of internal medicine, 1984, Volume: 101, Issue:5

    Topics: Animals; Azathioprine; Bone Marrow Transplantation; Chemical and Drug Induced Liver Injury; Cyclospo

1984
Primary lymphoma of the esophagus in a chronically immunosuppressed patient with hepatitis C infection: case report and review of the literature.
    The American journal of the medical sciences, 2001, Volume: 321, Issue:3

    Topics: Aged; Azathioprine; Esophageal Neoplasms; Hepatitis C; Humans; Immunosuppression Therapy; Immunosupp

2001
Review article: the risk of lymphoma associated with inflammatory bowel disease and immunosuppressive treatment.
    Alimentary pharmacology & therapeutics, 2001, Volume: 15, Issue:8

    Topics: Antibodies, Monoclonal; Azathioprine; Epidemiologic Studies; Gastrointestinal Agents; Humans; Immuno

2001
[Sarcoidosis therapy and its problems today].
    Deutsche medizinische Wochenschrift (1946), 1978, Feb-24, Volume: 103, Issue:8

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Anti-Inflammatory Agents; Antineoplasti

1978
The action of antitumor agents: a double-edged sword?
    Medical and pediatric oncology, 1977, Volume: 3, Issue:2

    Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma;

1977
The risks of antimalarial retinopathy, azathioprine lymphoma and methotrexate hepatotoxicity during the treatment of rheumatoid arthritis.
    Bailliere's clinical rheumatology, 1990, Volume: 4, Issue:2

    Topics: Antimalarials; Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Humans;

1990
[Blood hypereosinophilias. IV. Symptomatic hypereosinophilias: connective tissue diseases, neoplasms, blood diseases, various causes].
    Minerva medica, 1985, Jun-16, Volume: 76, Issue:25

    Topics: Aged; Asthma; Azathioprine; Connective Tissue Diseases; Cortisone; Eosinophilia; Female; Hematologic

1985
Immunosuppression and neoplasia. II. Is deficient immunesurveillance the only mechanism by which immunosuppression promotes neoplasia? A speculative review.
    Klinische Wochenschrift, 1973, Mar-15, Volume: 51, Issue:6

    Topics: Animals; Animals, Newborn; Antilymphocyte Serum; Antimetabolites; Azathioprine; Carcinogens; Cell Di

1973
Immunosuppression and neoplasia. I. A critical review of experimental carcinogenesis and the immunesurveillance theory.
    Klinische Wochenschrift, 1973, Mar-15, Volume: 51, Issue:6

    Topics: Animals; Antigens, Neoplasm; Antilymphocyte Serum; Autoantibodies; Azathioprine; Benz(a)Anthracenes;

1973
Murine leukemialike virus and the immunopathologic disorders of New Zealand black mice.
    The Journal of infectious diseases, 1969, Volume: 120, Issue:4

    Topics: Anemia, Hemolytic, Autoimmune; Animals; Animals, Newborn; Antigens; Autoimmune Diseases; Azathioprin

1969
Immunology in neoplasia relating to diagnosis, therapy and transplantation. Immunosuppression and oncogenesis.
    American journal of clinical pathology, 1974, Volume: 62, Issue:2

    Topics: Adenocarcinoma; Animals; Antilymphocyte Serum; Azathioprine; Carcinogens; Cortisone; Humans; Immunos

1974

Trials

5 trials available for azathioprine and Lymphoma

ArticleYear
Incidence and type of cancer following the use of OKT3: a single center experience with 557 organ transplants.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Adenoma, Bile Duct; Age Factors; Azathioprine; Cyclosporine; Follow-Up Studies; Humans; Immunosuppre

1993
Influence of antilymphocyte globulin upon the incidence of malignancies after kidney transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:3

    Topics: Adult; Age Factors; Antilymphocyte Serum; Azathioprine; Cyclosporine; Follow-Up Studies; Humans; Imm

1993
Tacrolimus in pancreas transplantation: a multicenter analysis. Tacrolimus Pancreas Transplant Study Group.
    Clinical transplantation, 1997, Volume: 11, Issue:4

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Bone Marrow Transplantation; Case-Control Studies; Cy

1997
Pharmaco-epidemiology--drugs, arthritis, and neoplasms: industry contribution to the data.
    The American journal of medicine, 1985, Jan-21, Volume: 78, Issue:1A

    Topics: Arthritis, Rheumatoid; Azathioprine; Clinical Trials as Topic; Computers; Drug Industry; Humans; Leu

1985
Azathioprine in the treatment of Crohn's disease.
    The British journal of surgery, 1972, Volume: 59, Issue:10

    Topics: Azathioprine; Clinical Trials as Topic; Colic; Crohn Disease; Humans; Leukopenia; Lymphoma; Placebos

1972

Other Studies

70 other studies available for azathioprine and Lymphoma

ArticleYear
Lack of Increased Risk of Lymphoma with Thiopurine Therapy Regardless of Dose and Duration of Treatment in Japanese Patients with Inflammatory Bowel Diseases.
    Digestion, 2022, Volume: 103, Issue:2

    Topics: Azathioprine; Duration of Therapy; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Ja

2022
Minimal risk of lymphoma and non-melanoma skin cancer despite long-term use of thiopurines in patients with inflammatory bowel disease: A longitudinal cohort analysis from northern India.
    Journal of gastroenterology and hepatology, 2022, Volume: 37, Issue:8

    Topics: Azathioprine; Cohort Studies; Colitis, Ulcerative; Crohn Disease; Humans; India; Inflammatory Bowel

2022
Association Between Use of Thiopurines or Tumor Necrosis Factor Antagonists Alone or in Combination and Risk of Lymphoma in Patients With Inflammatory Bowel Disease.
    JAMA, 2017, Nov-07, Volume: 318, Issue:17

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Cohort Studies; Drug Therapy,

2017
Azathioprine-induced reversible EBV-associated Hodgkin-like lymphoma after immunosuppressive therapy for autoimmune hepatitis
.
    International journal of clinical pharmacology and therapeutics, 2018, Volume: 56), Issue:3

    Topics: Azathioprine; Epstein-Barr Virus Infections; Hepatitis, Autoimmune; Herpesvirus 4, Human; Humans; Im

2018
Successful use of an immune checkpoint inhibitor in a patient with myasthenia gravis in remission.
    Muscle & nerve, 2019, Volume: 60, Issue:1

    Topics: Antineoplastic Agents, Immunological; Azathioprine; Central Nervous System Neoplasms; Cholinesterase

2019
Risk of lymphoma in patients with ulcerative colitis treated with thiopurines: a nationwide retrospective cohort study.
    Gastroenterology, 2013, Volume: 145, Issue:5

    Topics: Adult; Aged; Antibodies, Monoclonal; Azathioprine; Cohort Studies; Colitis, Ulcerative; Female; Foll

2013
Lymphoma: the bête noire of the long-term use of thiopurines in adult and elderly patients with inflammatory bowel disease.
    Gastroenterology, 2013, Volume: 145, Issue:5

    Topics: Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Female; Humans; Immunosuppressive Agents;

2013
Reply: To PMID 23891975.
    Gastroenterology, 2014, Volume: 146, Issue:4

    Topics: Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Female; Humans; Immunosuppressive Agents;

2014
Have we overestimated the risk of lymphoma associated with thiopurine treatment for ulcerative colitis?
    Gastroenterology, 2014, Volume: 146, Issue:4

    Topics: Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Female; Humans; Immunosuppressive Agents;

2014
The benefit-to-risk balance of combining infliximab with azathioprine varies with age: a markov model.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2015, Volume: 13, Issue:2

    Topics: Adult; Age Factors; Aged; Azathioprine; Communicable Diseases; Crohn Disease; Drug Therapy, Combinat

2015
Azathioprine induction of tumors with microsatellite instability: risk evaluation using a mouse model.
    Oncotarget, 2015, Sep-22, Volume: 6, Issue:28

    Topics: Adult; Aged; Animals; Azathioprine; Disease Models, Animal; DNA Mismatch Repair; Dose-Response Relat

2015
Lymphoma after living donor kidney transplantation: an Iranian multicenter experience.
    International urology and nephrology, 2008, Volume: 40, Issue:4

    Topics: Adult; Azathioprine; Chi-Square Distribution; Female; Humans; Immunosuppressive Agents; Incidence; I

2008
Risk of cancer in inflammatory bowel disease treated with azathioprine: a UK population-based case-control study.
    The American journal of gastroenterology, 2010, Volume: 105, Issue:7

    Topics: Adult; Aged; Antimetabolites; Azathioprine; Case-Control Studies; Chi-Square Distribution; Female; H

2010
Azathioprine-induced carcinogenesis in mice according to Msh2 genotype.
    Journal of the National Cancer Institute, 2010, Nov-17, Volume: 102, Issue:22

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Azathioprine; Carcinogens; Disease M

2010
Lymphoma with central nervous system involvement in a young patient with Crohn disease treated with azathioprine.
    Journal of pediatric gastroenterology and nutrition, 2010, Volume: 51, Issue:6

    Topics: Adolescent; Azathioprine; Brain Neoplasms; Crohn Disease; Female; Humans; Immunosuppressive Agents;

2010
Azathioprine and mercaptopurine: lymphoma.
    Prescrire international, 2011, Volume: 20, Issue:116

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lymphoma; Mercaptopurin

2011
Risk of malignant lymphoma in patients with inflammatory bowel diseases: a Dutch nationwide study.
    Inflammatory bowel diseases, 2011, Volume: 17, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Case-Control Studies; Child; Child, Presch

2011
Idiopathic retroperitoneal fibrosis mimicking malignant lymphoma.
    Pathology international, 2011, Volume: 61, Issue:11

    Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Biopsy; Clone Cells; Diagnosis,

2011
Role of thiopurine and anti-TNF therapy in lymphoma in inflammatory bowel disease.
    The American journal of gastroenterology, 2011, Volume: 106, Issue:12

    Topics: Adalimumab; Adolescent; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, M

2011
Prognosis of lymphoma in patients following treatment with 6-mercaptopurine/azathioprine for inflammatory bowel disease.
    Inflammatory bowel diseases, 2012, Volume: 18, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Colitis, Ulcerative; Crohn Disease; Female

2012
Long-term risk of malignancy after treatment of inflammatory bowel disease with azathioprine.
    Alimentary pharmacology & therapeutics, 2002, Volume: 16, Issue:7

    Topics: Adolescent; Adult; Age Distribution; Aged; Azathioprine; Colorectal Neoplasms; Drug Administration S

2002
Risks and benefits of azathioprine therapy.
    Gut, 2005, Volume: 54, Issue:8

    Topics: Antimetabolites; Azathioprine; Humans; Inflammatory Bowel Diseases; Lymphoma; Risk Factors; Severity

2005
Primary CNS lymphoma in myasthenic on long-term azathioprine.
    Journal of neuro-oncology, 2005, Volume: 74, Issue:1

    Topics: Antigens, CD20; Antimetabolites, Antineoplastic; Azathioprine; Brain Neoplasms; Diagnosis, Different

2005
Lymphoma after Imuran and 6-MP: a new look.
    Journal of pediatric gastroenterology and nutrition, 2005, Volume: 41, Issue:5

    Topics: Azathioprine; Humans; Inflammatory Bowel Diseases; Lymphoma; Mercaptopurine; Risk Factors

2005
Risk of lymphoma: inflammatory bowel disease and immunomodulators.
    Gut, 2006, Volume: 55, Issue:4

    Topics: Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Lymphoma; Mercaptopurin

2006
Acute graft-versus-host disease of the lung with atypical presentation.
    International journal of hematology, 2006, Volume: 84, Issue:1

    Topics: Acute Disease; Anti-Inflammatory Agents; Azathioprine; Graft vs Host Disease; Hematopoietic Stem Cel

2006
Cancer risk and impact of disease-modifying treatments in patients with multiple sclerosis.
    Multiple sclerosis (Houndmills, Basingstoke, England), 2008, Volume: 14, Issue:3

    Topics: Adult; Azathioprine; Breast Neoplasms; Central Nervous System Neoplasms; Cyclophosphamide; Digestive

2008
Studies on long-term T-cell-mediated immunity to Epstein-BArr virus in immunosuppressed renal allograft recipients.
    International journal of cancer, 1981, Volume: 28, Issue:6

    Topics: Azathioprine; Cyclosporins; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Kidney Transplan

1981
A case of the hypereosinophilic syndrome complicated by malignant lymphoma.
    The Journal of dermatology, 1983, Volume: 10, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Brain Neoplasms; Eosinophilia; Female; Humans; Lymphoma; Prednisolo

1983
Necrotizing vasculitis (angiitis) with granulomatosis.
    International journal of dermatology, 1984, Volume: 23, Issue:2

    Topics: Azathioprine; Chlorambucil; Cyclophosphamide; Diagnosis, Differential; Granuloma, Lethal Midline; Gr

1984
Azathioprine induction of lymphomas and squamous cell carcinomas in rats.
    Cancer research, 1983, Volume: 43, Issue:6

    Topics: Animals; Azathioprine; Carcinoma, Squamous Cell; Ear Neoplasms; Female; Lymphoma; Rats; Rats, Inbred

1983
Lymphoma and leukaemia due to drugs.
    British journal of hospital medicine, 1980, Volume: 24, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Bone Marrow Diseases; Child; Female; Hodgkin Disease;

1980
[Malignant tumors in bearers of kidney grafts in immunosuppressive therapy].
    Schweizerische medizinische Wochenschrift, 1982, Jan-23, Volume: 112, Issue:4

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Breast Neoplasms; Dysgerminoma; Female; Humans; Immunosup

1982
The comparative incidence of malignant disease in rheumatoid arthritics exposed to different treatment regimens.
    Annals of the rheumatic diseases, 1982, Volume: 41 Suppl 1

    Topics: Adult; Aged; Animals; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Transitional Cell; Chromosome

1982
Decreased incidence of lymphomas after heart transplantation under low-dose immunosuppression.
    Transplantation proceedings, 1995, Volume: 27, Issue:2

    Topics: Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Female; Heart Transplantation; Humans; Immu

1995
Prognosis of posttransplant lymphomas in patients treated with cyclosporine, azathioprine, and prednisolone.
    Transplantation proceedings, 1994, Volume: 26, Issue:4

    Topics: Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Graft Survival; Humans; Immuno

1994
Cyclosporine and other immunosuppressive agents: current and future role in the treatment of inflammatory bowel disease.
    The American journal of gastroenterology, 1993, Volume: 88, Issue:5

    Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Cyclosporine; Humans; Immunosuppressive Agents; In

1993
Cancers in cyclosporine-treated vs azathioprine-treated patients.
    Transplantation proceedings, 1996, Volume: 28, Issue:2

    Topics: Adult; Azathioprine; Child; Cyclosporine; Female; Humans; Immunosuppressive Agents; Kidney Neoplasms

1996
Heart transplantation for chronic Chagas' heart disease.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:6

    Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Cause of Death; Chagas Cardiomyopathy; Child; C

1996
Postransplant lymphoproliferative disease following renal transplantation: a multicenter retrospective study of 41 cases observed between 1992 and 1996. French Speaking Transplantation Workshop.
    Transplantation proceedings, 1998, Volume: 30, Issue:6

    Topics: Azathioprine; Cyclosporine; Drug Therapy, Combination; Humans; Immunophenotyping; Immunosuppression

1998
Association of primary central nervous system lymphoma with long-term azathioprine therapy for myasthenia gravis?
    Annals of neurology, 2000, Volume: 47, Issue:5

    Topics: Aged; Azathioprine; Central Nervous System Neoplasms; Humans; Immunosuppressive Agents; Lymphoma; Mi

2000
Epstein-Barr virus-positive lymphoma in patients with inflammatory bowel disease treated with azathioprine or 6-mercaptopurine.
    Gastroenterology, 2002, Volume: 122, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Azathioprine; Epstein-Barr Virus Infections; Female; Herpesvirus 4,

2002
Primary malignant lymphoma of the CNS and polyneuropathy in a patient with necrotizing vasculitis treated with immunosuppression.
    Journal of neurology, 1979, Jan-05, Volume: 220, Issue:4

    Topics: Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppressive Agents; Lymphoma; Middle Aged; Necr

1979
Collaborative United Kingdom-Australasian study of cancer in patients treated with immunosuppressive drugs.
    British medical journal, 1979, Dec-08, Volume: 2, Issue:6203

    Topics: Adolescent; Adult; Aged; Australia; Azathioprine; Chlorambucil; Cyclophosphamide; Female; Follow-Up

1979
The oncogenic effect of immunosuppressive (cytotoxic) agents in (NZB x NZW) mice. II. Emergence of tumors in young animals treated with azathioprine and ifosfamide, including a histologic assessment of the neoplasms.
    Arzneimittel-Forschung, 1979, Volume: 29, Issue:4

    Topics: Animals; Azathioprine; Carcinogens; Carcinoma; Cyclophosphamide; Female; Hyperplasia; Ifosfamide; Ly

1979
Lymphomatoid granulomatosis after immunosuppression for pemphigus.
    Archives of dermatology, 1978, Volume: 114, Issue:7

    Topics: Aged; Autopsy; Azathioprine; Granuloma; Humans; Immunosuppressive Agents; Lung; Lymphoma; Male; Pemp

1978
The significance of immunosuppression and antigenic stimulation in the development of malignant lymphomas.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1975, Issue:52

    Topics: Animals; Antibody-Producing Cells; Antigen-Antibody Reactions; Antineoplastic Agents; Azathioprine;

1975
[Changes in the lymphoreticular system of animals following long-term immunization with antityphoid vaccine].
    Polski tygodnik lekarski (Warsaw, Poland : 1960), 1975, Jan-20, Volume: 30, Issue:3

    Topics: Animals; Azathioprine; B-Lymphocytes; Cricetinae; Disease Models, Animal; Female; Guinea Pigs; Haplo

1975
Changes in the lymphoreticular system of Swiss mice subjected to antigenic stimulation, immunosuppression, or both.
    Archivum immunologiae et therapiae experimentalis, 1977, Volume: 25, Issue:2

    Topics: Animals; Azathioprine; Burkitt Lymphoma; Female; Immunization; Immunosuppression Therapy; Lymphatic

1977
[Side effects in immunosuppressive therapy].
    Acta medica Austriaca, 1975, Volume: 2, Issue:4

    Topics: Alopecia; Amenorrhea; Anemia; Azathioprine; Bacterial Infections; Chlorambucil; Female; Humans; Immu

1975
Treatment of end-stage chronic obstructive pulmonary disease with double lung transplantation.
    Chest, 1991, Volume: 99, Issue:3

    Topics: Adult; Antibodies, Monoclonal; Azathioprine; Cyclosporins; Cytomegalovirus Infections; Emphysema; Fe

1991
Induction of uterine hemangioendothelioma and lymphoma in (C57BL/6N x C3H/2N)F1 mice by oral administration of azathioprine.
    Japanese journal of cancer research : Gann, 1989, Volume: 80, Issue:5

    Topics: Administration, Oral; Animals; Azathioprine; Body Weight; Female; Hemangioendothelioma; Lymphoma; Ma

1989
Increased frequency of posttransplant lymphomas in patients treated with cyclosporin, azathioprine, and prednisone.
    Transplantation proceedings, 1989, Volume: 21, Issue:1 Pt 3

    Topics: Azathioprine; Cyclosporins; Drug Therapy, Combination; Heart Transplantation; Humans; Immunosuppress

1989
[Crohn disease: initial experiences with cyclosporin A in an adolescent girl].
    Deutsche medizinische Wochenschrift (1946), 1985, Mar-01, Volume: 110, Issue:9

    Topics: Adolescent; Azathioprine; Crohn Disease; Cyclosporins; Female; Humans; Lymphoma; Osteoporosis; Predn

1985
Lymphoproliferative cancer and other malignancy in patients with rheumatoid arthritis treated with azathioprine: a 20 year follow up study.
    Annals of the rheumatic diseases, 1988, Volume: 47, Issue:12

    Topics: Arthritis, Rheumatoid; Azathioprine; Follow-Up Studies; Lymphoma; Lymphoma, Non-Hodgkin; Neoplasms;

1988
De novo malignancies after liver transplantation.
    Transplantation proceedings, 1988, Volume: 20, Issue:1

    Topics: Adenocarcinoma; Adolescent; Adult; Aged; Azathioprine; Child; Colonic Neoplasms; Cyclosporins; Dysge

1988
[Malignant neoplastic pathology in patients given a kidney transplant].
    Chirurgia italiana, 1987, Volume: 39, Issue:3

    Topics: Azathioprine; Humans; Immunosuppression Therapy; Kidney Transplantation; Lymphoma; Neoplasms; Sarcom

1987
Polyclonal lymphoma confined to renal allograft: case report.
    Transplantation proceedings, 1987, Volume: 19, Issue:5

    Topics: Adult; Azathioprine; Cyclosporins; Humans; Immunosuppression Therapy; Kidney Neoplasms; Kidney Trans

1987
Neoplasia in immunosuppressed renal transplant patients: a 20-year experience.
    Southern medical journal, 1985, Volume: 78, Issue:5

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Azathioprine; Cadaver; Child; Child, Preschool; Cyclo

1985
Incidence of neoplasms in patients with rheumatoid arthritis exposed to different treatment regimens.
    The American journal of medicine, 1985, Jan-21, Volume: 78, Issue:1A

    Topics: Arthritis, Rheumatoid; Azathioprine; Chlorambucil; Cyclophosphamide; Cystitis; Humans; Immunosuppres

1985
Incidence of cancer in rheumatoid arthritis and other disorders after immunosuppressive treatment.
    The American journal of medicine, 1985, Jan-21, Volume: 78, Issue:1A

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squa

1985
De-novo brain tumours in renal-transplant recipients.
    Lancet (London, England), 1971, May-15, Volume: 1, Issue:7707

    Topics: Adolescent; Adult; Azathioprine; Brain; Brain Neoplasms; Cadaver; Follow-Up Studies; Humans; Immunos

1971
Immunosuppression and intracerebral lymphomas.
    Lancet (London, England), 1971, Jul-17, Volume: 2, Issue:7716

    Topics: Adolescent; Adult; Age Factors; Azathioprine; Brain Neoplasms; Humans; Immune Tolerance; Immunosuppr

1971
Azathioprine (Imuran) administration and the development of malignant lymphomas in NZB mice.
    Clinical and experimental immunology, 1968, Volume: 3, Issue:4

    Topics: Albuminuria; Anemia, Hemolytic, Autoimmune; Animals; Azathioprine; Coombs Test; Glomerulonephritis;

1968
Neurology and neuropathology of immunosuppressive therapy and acquired immunological deficiency.
    Research publications - Association for Research in Nervous and Mental Disease, 1971, Volume: 49

    Topics: Adolescent; Adult; Agammaglobulinemia; Aspergillus; Azathioprine; Brain; Brain Diseases; Candida; Ce

1971
Synergistic action of N-nitrosobutylurea and azathioprine in induction of leukemia in C57BL mice.
    Gan, 1973, Volume: 64, Issue:5

    Topics: AKR murine leukemia virus; Animals; Antigens, Viral; Azathioprine; Drug Synergism; Female; Immune Se

1973
Malignant lymphomas in transplantation patients.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Brain Neoplasms; Female; Humans; Immunosuppre

1969
Preliminary results with azathioprine treatment in rheumatoid arthritis.
    Annals of physical medicine, 1969, Volume: 10, Issue:4

    Topics: Alkaline Phosphatase; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Drug Synergism; Fem

1969
The development of lymphomas in mice with autoimmune disorders treated with azathioprine.
    Blood, 1968, Volume: 31, Issue:3

    Topics: Animals; Autoimmune Diseases; Azathioprine; Female; Injections, Intramuscular; Lupus Erythematosus,

1968
Effect of antilymphocytic and antithymocytic sera on the development of mouse lymphoma.
    Cancer research, 1969, Volume: 29, Issue:9

    Topics: AKR murine leukemia virus; Animals; Antilymphocyte Serum; Azathioprine; Hemagglutination; Immune Ser

1969