azathioprine has been researched along with Lupus Erythematosus, Discoid in 19 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Lupus Erythematosus, Discoid: A chronic form of cutaneous lupus erythematosus (LUPUS ERYTHEMATOSUS, CUTANEOUS) in which the skin lesions mimic those of the systemic form but in which systemic signs are rare. It is characterized by the presence of discoid skin plaques showing varying degrees of edema, erythema, scaliness, follicular plugging, and skin atrophy. Lesions are surrounded by an elevated erythematous border. The condition typically involves the face and scalp, but widespread dissemination may occur.
| Excerpt | Relevance | Reference |
|---|---|---|
| " After a 2-month course of treatment with hydroxychloroquine dosage of 200 mg per day and a break of 3 months between courses, we observed a complete remission." | 1.43 | Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem. ( Bakardzhiev, I; Chokoeva, AA; Krasnaliev, I; Lotti, T; Tana, C; Tchernev, G; Wollina, U, 2016) |
| "Hypogonadism has been established as a cause of osteoporosis in males, and in this case would explain the occurrence of fractures in the absence of other major risk factors." | 1.31 | Osteoporosis with underlying connective tissue disease: an unusual case. ( De Silva, M; Prasad, R, 2002) |
| " The skin lesions responded dramatically to 100 mg of azathioprine sodium daily, flared when the drug treatment was discontinued, and again responded on reinstatement of the same dosage of azathioprine." | 1.27 | Successful treatment of generalized discoid skin lesions with azathioprine. Its use in a patient with systemic lupus erythematosus. ( Caughman, SW; Klippel, JH; Tsokos, GC, 1985) |
| "A patient with discoid lupus erythematosus is reported which turned into a mixed connective tissue disease (MCTD) within five months." | 1.26 | [Development of "mixed connective tissue disease" (MCTD) from discoid lupus erythematosus]. ( Bauer, R; Orfanos, CE; Schultz-Ehrenburg, U, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 2 (10.53) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 3 (15.79) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Bardazzi, F | 1 |
| Gallo, G | 1 |
| Loi, C | 1 |
| Misciali, C | 1 |
| Patrizi, A | 1 |
| Filippini, A | 1 |
| Tedeschi, SK | 1 |
| Massarotti, E | 1 |
| Guan, H | 1 |
| Fine, A | 1 |
| Bermas, BL | 1 |
| Costenbader, KH | 1 |
| Bakardzhiev, I | 1 |
| Chokoeva, AA | 1 |
| Krasnaliev, I | 1 |
| Tana, C | 1 |
| Wollina, U | 1 |
| Lotti, T | 1 |
| Tchernev, G | 1 |
| Knott, HM | 1 |
| Martínez, JD | 1 |
| Prasad, R | 1 |
| De Silva, M | 1 |
| Eisenbach, C | 1 |
| Goeggelmann, C | 1 |
| Flechtenmacher, C | 1 |
| Stremmel, W | 1 |
| Encke, J | 1 |
| Bauer, R | 1 |
| Schultz-Ehrenburg, U | 1 |
| Orfanos, CE | 1 |
| Callen, JP | 1 |
| Tulokas, S | 1 |
| Schulze, P | 1 |
| Krupko, MI | 1 |
| Gorbunov, VF | 1 |
| Domaseva, TV | 1 |
| Ashinoff, R | 1 |
| Werth, VP | 1 |
| Franks, AG | 1 |
| Werth, V | 1 |
| Franks, A | 1 |
| Shehade, S | 1 |
| van Joost, T | 1 |
| Stolz, E | 1 |
| Habets, W | 1 |
| Notowicz, A | 1 |
| Tsokos, GC | 1 |
| Caughman, SW | 1 |
| Klippel, JH | 1 |
| Asamer, H | 1 |
| Land, W | 1 |
| Brendel, W | 1 |
| Hopf, U | 1 |
| Seifert, J | 1 |
| Winkelmann, RK | 1 |
3 reviews available for azathioprine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
Refractory palmo-plantar discoid lupus erythematosus successfully treated with mycophenolate mofetil: Unusual localization and literature review.
Topics: Azathioprine; Female; Hand; Humans; Lupus Erythematosus, Discoid; Middle Aged; Mycophenolic Acid; Tr | 2021 |
Treatment of cutaneous lesions in patients with lupus erythematosus.
Topics: Adrenal Cortex Hormones; Antimalarials; Azathioprine; Combined Modality Therapy; Dapsone; Drug Thera | 1994 |
[Indications and limits of long-term therapy with immunosuppressive (and cytostatic) agents in various chronic skin diseases].
Topics: Arthritis, Reactive; Azathioprine; Chronic Disease; Cyclophosphamide; Dermatomyositis; Humans; Immun | 1977 |
1 trial available for azathioprine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
[Evaluation of the effectiveness of the imuran treatment of lupus erythematosus].
Topics: Adult; Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Imm | 1977 |
15 other studies available for azathioprine and Lupus Erythematosus, Discoid
| Article | Year |
|---|---|
Specific systemic lupus erythematosus disease manifestations in the six months prior to conception are associated with similar disease manifestations during pregnancy.
Topics: Adult; Antirheumatic Agents; Azathioprine; Female; Humans; Hydroxychloroquine; Logistic Models; Lupu | 2015 |
Unilateral unique Lupus tumidus: pathogenetic mystery and diagnostic problem.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Biopsy; Chloroquine; Combined Modality Therapy; Dapson | 2016 |
Innovative management of lupus erythematosus.
Topics: Administration, Topical; Adolescent; Adult; Anti-Inflammatory Agents; Antimalarials; Azathioprine; C | 2010 |
Osteoporosis with underlying connective tissue disease: an unusual case.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Accidental Falls; Adult; Anti-Ulcer Agents; Antibodies, Ant | 2002 |
Severe cholestatic hepatitis caused by azathioprine.
Topics: Aged; Azathioprine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Humans; Liver | 2005 |
[Development of "mixed connective tissue disease" (MCTD) from discoid lupus erythematosus].
Topics: Antibodies, Antinuclear; Azathioprine; Female; Humans; Lupus Erythematosus, Discoid; Middle Aged; Mi | 1981 |
[The activation of lupus in pregnancy and its successful immunological treatment].
Topics: Adult; Anti-Inflammatory Agents; Anticonvulsants; Azathioprine; Epilepsy; Female; Humans; Immunoglob | 1994 |
Resistant discoid lupus erythematosus of palms and soles: successful treatment with azathioprine.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Drug Resistance; Female; Foot Dermatoses; Hand Dermat | 1988 |
Treatment of discoid skin lesions with azathioprine.
Topics: Azathioprine; Female; Humans; Hydroxychloroquine; Lupus Erythematosus, Discoid; Quinacrine | 1986 |
Successful treatment of generalized discoid skin lesions with azathioprine.
Topics: Azathioprine; Female; Humans; Lupus Erythematosus, Discoid; Middle Aged | 1986 |
[Chronic discoid lupus erythematosus; who is afraid of the red wolf?].
Topics: Adult; Alopecia; Antimalarials; Azathioprine; Facial Dermatoses; Female; Glossitis; Humans; Lupus Er | 1985 |
Successful treatment of generalized discoid skin lesions with azathioprine. Its use in a patient with systemic lupus erythematosus.
Topics: Adult; Azathioprine; Female; Humans; Lupus Erythematosus, Discoid; Lupus Erythematosus, Systemic; Sy | 1985 |
[Successes and failures of immunosuppressive therapy in nephropathies].
Topics: Adult; Anti-Glomerular Basement Membrane Disease; Azathioprine; Chronic Disease; Cortisone; Cyclopho | 1974 |
[Attempt for an induction of immune tolerance against horse IgG in men].
Topics: Adult; Antibodies; Antibody Formation; Antigens; Antilymphocyte Serum; Azathioprine; Female; Hemaggl | 1970 |
Chronic discoid lupus in children.
Topics: Adolescent; Azathioprine; Child; Humans; Lupus Erythematosus, Discoid; Male | 1968 |