azathioprine has been researched along with Low Bone Density in 4 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "At the distal radius, osteopenia was found in all the groups." | 2.69 | Bone loss in long-term renal transplantation: histopathology and densitometry analysis. ( Adams, JE; Crowley, V; Cueto-Manzano, AM; France, MW; Freemont, AJ; Gokal, R; Hutchison, AJ; Konel, S; Mawer, B, 1999) |
| "There is a high prevalence of low bone mineral density (BMD) among patients with inflammatory bowel disease (IBD) although there is a lack of clinical data on the impact of IBD specific medications and recommended vitamin D (VD) and calcium (Ca) supplements on it." | 1.40 | Combination therapy with an immunomodulator and anti-TNFα agent improves bone mineral density in IBD patients. ( Cierny, D; Hlavaty, T; Huorka, M; Killinger, Z; Koller, T; Krajcovicova, A; Letkovsky, J; Miznerova, E; Nevidanska, M; Payer, J; Toth, J; Zelinkova, Z, 2014) |
| "Osteoporosis, osteopenia, and osteonecrosis are common in renal transplant recipients." | 1.36 | Bone disease in renal transplantation and pleotropic effects of vitamin D therapy. ( Balal, M; Binokay, F; Demir, E; Erken, U; Kurt, C; Paydas, S; Sertdemir, Y; Sikgenc, MM, 2010) |
| "Azathioprine treatment alone did not alter ionized calcium, 1,25(OH)2VitD, or PTH levels." | 1.29 | Azathioprine alone is bone sparing and does not alter cyclosporin A-induced osteopenia in the rat. ( Armstrong, EC; Bryer, HP; Buchinsky, FJ; Epstein, S; Isserow, JA; Mann, GN; Romero, DF; Rucinski, B, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krajcovicova, A | 1 |
| Hlavaty, T | 1 |
| Killinger, Z | 1 |
| Miznerova, E | 1 |
| Toth, J | 1 |
| Letkovsky, J | 1 |
| Nevidanska, M | 1 |
| Cierny, D | 1 |
| Koller, T | 1 |
| Zelinkova, Z | 1 |
| Huorka, M | 1 |
| Payer, J | 1 |
| Sikgenc, MM | 1 |
| Paydas, S | 1 |
| Balal, M | 1 |
| Demir, E | 1 |
| Kurt, C | 1 |
| Sertdemir, Y | 1 |
| Binokay, F | 1 |
| Erken, U | 1 |
| Bryer, HP | 1 |
| Isserow, JA | 1 |
| Armstrong, EC | 1 |
| Mann, GN | 1 |
| Rucinski, B | 1 |
| Buchinsky, FJ | 1 |
| Romero, DF | 1 |
| Epstein, S | 1 |
| Cueto-Manzano, AM | 1 |
| Konel, S | 1 |
| Hutchison, AJ | 1 |
| Crowley, V | 1 |
| France, MW | 1 |
| Freemont, AJ | 1 |
| Adams, JE | 1 |
| Mawer, B | 1 |
| Gokal, R | 1 |
1 trial available for azathioprine and Low Bone Density
| Article | Year |
|---|---|
Bone loss in long-term renal transplantation: histopathology and densitometry analysis.
Topics: Absorptiometry, Photon; Adult; Age Factors; Anti-Inflammatory Agents; Azathioprine; Bone Density; Bo | 1999 |
3 other studies available for azathioprine and Low Bone Density
| Article | Year |
|---|---|
Combination therapy with an immunomodulator and anti-TNFα agent improves bone mineral density in IBD patients.
Topics: Absorptiometry, Photon; Adalimumab; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; A | 2014 |
Bone disease in renal transplantation and pleotropic effects of vitamin D therapy.
Topics: Azathioprine; Bone Density; Bone Diseases; Bone Diseases, Metabolic; Creatinine; Female; Humans; Kid | 2010 |
Azathioprine alone is bone sparing and does not alter cyclosporin A-induced osteopenia in the rat.
Topics: Animals; Azathioprine; Body Weight; Bone Diseases, Metabolic; Calcitriol; Calcium; Cyclosporine; Dis | 1995 |