azathioprine has been researched along with Local Neoplasm Recurrence in 26 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Secondary outcomes were annual relapse rate, disability accumulation, drug persistence, and adverse events." | 5.72 | Efficacy and safety of azathioprine, mycophenolate mofetil, and reduced dose of rituximab in neuromyelitis optica spectrum disorder. ( Chang, X; Du, L; Huang, W; Li, Q; Li, W; Lu, C; Lu, J; Ma, J; Pan, J; Quan, C; Tan, H; Wang, B; Wang, L; Wang, M; Xia, J; Yu, J; ZhangBao, J; Zhao, C; Zhou, L, 2022) |
| "We assessed two patients with multiple sclerosis who were on treatment with dimethylfumarate (DMF) preceded by long-term azathioprine therapy." | 3.88 | Altered epigenetic pathways and cell cycle dysregulation in healthy appearing skin of patients with koebnerized squamous cell carcinomas following skin surgery. ( Bechara, FG; Gambichler, T; Hessam, S; Rüddel, I; Schmitz, L; Stockfleth, E, 2018) |
| "The risk of breast cancer recurrence in patients who received methotrexate, thiopurine, or anti-TNF therapy was not statistically significantly increased, although we cannot rule out a 2-fold or greater increased risk in those treated with thiopurines." | 3.83 | Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study. ( Boursi, B; Brensinger, CM; Chen, L; Clark, AS; Curtis, JR; Lewis, JD; Mamtani, R; Osterman, MT; Scott, FI; Xie, F; Yun, H, 2016) |
| " Here we report the case of a patient with myasthenia gravis receiving long-term immunosuppression with azathioprine and recurrent well-differentiated thymic carcinoma who developed CD4+ T-cell depletion and CNS cryptococcosis after multiple courses of chemotherapy and mediastinal irradiation." | 3.70 | Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis. ( Padberg, F; Schmidt, S, 1998) |
| " Secondary outcomes were annual relapse rate, disability accumulation, drug persistence, and adverse events." | 1.72 | Efficacy and safety of azathioprine, mycophenolate mofetil, and reduced dose of rituximab in neuromyelitis optica spectrum disorder. ( Chang, X; Du, L; Huang, W; Li, Q; Li, W; Lu, C; Lu, J; Ma, J; Pan, J; Quan, C; Tan, H; Wang, B; Wang, L; Wang, M; Xia, J; Yu, J; ZhangBao, J; Zhao, C; Zhou, L, 2022) |
| "Demyelination is similar with malignancy in clinical symptoms." | 1.72 | Astrocytoma with myelin oligodendrocyte glycoprotein antibody associated encephalomyelitis: A case report. ( Gu, H; Liu, X; Yang, S; Zhang, J; Zhong, G, 2022) |
| "GCs+azathioprine seem the best treatment in the event of relapse." | 1.72 | Efficacy and safety of treatments in cutaneous polyarteritis nodosa: A French observational retrospective study. ( Aractingi, S; Bettuzzi, T; Bouaziz, JD; Chasset, F; Cordoliani, F; Dupin, N; Frumholtz, L; Guillevin, L; Jachiet, M; Mouthon, L; Paule, R; Régent, A; Sbidian, E; Terrier, B, 2022) |
| "Pathology revealed T1aNxM0 pleomorphic malignant fibrous histiocytoma or undifferentiated pleomorphic sarcoma." | 1.38 | Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis. ( Daw, HA; Sood, R, 2012) |
| "The risk of skin cancer is highly increased in kidney-transplant recipients (KTR), but the risk of subsequent skin cancers is less well studied." | 1.36 | Subsequent squamous- and basal-cell carcinomas in kidney-transplant recipients after the first skin cancer: cumulative incidence and risk factors. ( Bavinck, JN; Claas, FH; de Fijter, JW; Edelbroek, JR; Haasnoot, GW; Willemze, R; Wisgerhof, HC, 2010) |
| "In 7 transplant recipients with skin cancer, the mean SCE frequency was 14." | 1.27 | Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer. ( Kelly, GE; Sheil, AG, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (30.77) | 18.7374 |
| 1990's | 5 (19.23) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (30.77) | 24.3611 |
| 2020's | 5 (19.23) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, W | 1 |
| Wang, L | 1 |
| Xia, J | 1 |
| Li, W | 1 |
| Wang, M | 1 |
| Yu, J | 1 |
| Li, Q | 1 |
| Wang, B | 1 |
| Pan, J | 1 |
| Du, L | 1 |
| Ma, J | 1 |
| Tan, H | 1 |
| Chang, X | 1 |
| Lu, C | 1 |
| Zhao, C | 1 |
| Lu, J | 1 |
| Zhou, L | 1 |
| ZhangBao, J | 1 |
| Quan, C | 1 |
| Paybast, S | 1 |
| Emami, A | 1 |
| Baghalha, F | 1 |
| Naser Moghadasi, A | 1 |
| Zhong, G | 1 |
| Zhang, J | 1 |
| Liu, X | 1 |
| Yang, S | 1 |
| Gu, H | 1 |
| Ssemmanda, S | 1 |
| Musubire, AK | 1 |
| Bettuzzi, T | 1 |
| Jachiet, M | 1 |
| Sbidian, E | 1 |
| Frumholtz, L | 1 |
| Cordoliani, F | 1 |
| Mouthon, L | 1 |
| Chasset, F | 1 |
| Paule, R | 1 |
| Bouaziz, JD | 1 |
| Guillevin, L | 1 |
| Terrier, B | 1 |
| Aractingi, S | 1 |
| Dupin, N | 1 |
| Régent, A | 1 |
| Gambichler, T | 1 |
| Rüddel, I | 1 |
| Hessam, S | 1 |
| Bechara, FG | 1 |
| Stockfleth, E | 1 |
| Schmitz, L | 1 |
| Jordan, B | 1 |
| Zierz, S | 1 |
| Weber, T | 1 |
| Jordan, K | 1 |
| Rodríguez-Perálvarez, M | 1 |
| De la Mata, M | 1 |
| Burroughs, AK | 1 |
| Peiris-Pagès, M | 1 |
| Smith, DL | 1 |
| Győrffy, B | 1 |
| Sotgia, F | 1 |
| Lisanti, MP | 1 |
| Mamtani, R | 1 |
| Clark, AS | 1 |
| Scott, FI | 1 |
| Brensinger, CM | 1 |
| Boursi, B | 1 |
| Chen, L | 1 |
| Xie, F | 1 |
| Yun, H | 1 |
| Osterman, MT | 1 |
| Curtis, JR | 1 |
| Lewis, JD | 1 |
| Wisgerhof, HC | 1 |
| Edelbroek, JR | 1 |
| de Fijter, JW | 1 |
| Haasnoot, GW | 1 |
| Claas, FH | 1 |
| Willemze, R | 1 |
| Bavinck, JN | 1 |
| Sood, R | 1 |
| Daw, HA | 1 |
| Wagner, JA | 1 |
| Kelly, GE | 1 |
| Sheil, AG | 1 |
| Luderschmidt, C | 1 |
| Hillebrand, G | 1 |
| Castro, LA | 1 |
| Hammer, C | 1 |
| Euvrard, S | 1 |
| Kanitakis, J | 1 |
| Pouteil-Noble, C | 1 |
| Disant, F | 1 |
| Dureau, G | 1 |
| Finaz de Villaine, J | 1 |
| Claudy, A | 1 |
| Thivolet, J | 1 |
| Johnson, F | 1 |
| Hunt, S | 1 |
| Plumb, R | 1 |
| Doolittle, GC | 1 |
| Schmidt, S | 1 |
| Padberg, F | 1 |
| Veness, MJ | 1 |
| O'Grady, JG | 1 |
| Johnson, PJ | 1 |
| Zaman, S | 1 |
| Calne, RY | 1 |
| Williams, R | 1 |
| Dahlem, K | 1 |
| Osterwald, L | 1 |
| Alpert, E | 1 |
| Starzl, TE | 1 |
| Schur, PH | 1 |
| Isselbacher, KJ | 1 |
| Jacobsson, S | 1 |
| Linell, F | 1 |
| Rausing, A | 1 |
| Van der Riet, Fde S | 1 |
| Kahn, LB | 1 |
| Lowney, ED | 1 |
2 reviews available for azathioprine and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Watch out for neuromyelitis optica spectrum disorder onset or clinical relapse after COVID-19 vaccination: What neurologists need to know?
Topics: Aquaporin 4; Azathioprine; COVID-19; COVID-19 Vaccines; Female; Humans; Male; Middle Aged; Neoplasm | 2022 |
Liver transplantation: immunosuppression and oncology.
Topics: Antilymphocyte Serum; Azathioprine; Calcineurin Inhibitors; Carcinoma, Hepatocellular; Humans; Immun | 2014 |
24 other studies available for azathioprine and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Efficacy and safety of azathioprine, mycophenolate mofetil, and reduced dose of rituximab in neuromyelitis optica spectrum disorder.
Topics: Autoantibodies; Azathioprine; Humans; Immunosuppressive Agents; Mycophenolic Acid; Neoplasm Recurren | 2022 |
Astrocytoma with myelin oligodendrocyte glycoprotein antibody associated encephalomyelitis: A case report.
Topics: Aquaporin 4; Astrocytoma; Autoantibodies; Azathioprine; Demyelinating Diseases; Dizziness; Encephalo | 2022 |
Different clinical phenotypes of AQP4-IgG positive NMOSD in two first degree relatives.
Topics: Adult; Autoimmune Diseases; Azathioprine; Female; Gadolinium; HIV Infections; Humans; Immunoglobulin | 2023 |
Efficacy and safety of treatments in cutaneous polyarteritis nodosa: A French observational retrospective study.
Topics: Azathioprine; Colchicine; Glucocorticoids; Humans; Neoplasm Recurrence, Local; Polyarteritis Nodosa; | 2022 |
Altered epigenetic pathways and cell cycle dysregulation in healthy appearing skin of patients with koebnerized squamous cell carcinomas following skin surgery.
Topics: 5-Methylcytosine; Azathioprine; Carcinoma, Squamous Cell; Cell Cycle; Cyclin-Dependent Kinase Inhibi | 2018 |
Successful use of an immune checkpoint inhibitor in a patient with myasthenia gravis in remission.
Topics: Antineoplastic Agents, Immunological; Azathioprine; Central Nervous System Neoplasms; Cholinesterase | 2019 |
Proteomic identification of prognostic tumour biomarkers, using chemotherapy-induced cancer-associated fibroblasts.
Topics: Antineoplastic Agents; Antioxidants; Autophagy; Azathioprine; Biomarkers, Tumor; Cell Differentiatio | 2015 |
Association Between Breast Cancer Recurrence and Immunosuppression in Rheumatoid Arthritis and Inflammatory Bowel Disease: A Cohort Study.
Topics: Adalimumab; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Azathioprine; Breast Neoplasms; Cohort S | 2016 |
Subsequent squamous- and basal-cell carcinomas in kidney-transplant recipients after the first skin cancer: cumulative incidence and risk factors.
Topics: Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Immunosuppressive Age | 2010 |
Pleomorphic malignant histiocytoma: a rare skin cancer in a patient on azathioprine for ulcerative colitis.
Topics: Aged; Azathioprine; Colitis, Ulcerative; Female; Histiocytoma, Malignant Fibrous; Humans; Immunosupp | 2012 |
Cancer after heart transplant: implications for practice.
Topics: Azathioprine; Carcinoma, Squamous Cell; Drug Therapy, Combination; Fatal Outcome; Glucocorticoids; H | 2012 |
Sister chromatid exchange in lymphocytes from renal transplant recipients with and without cancer.
Topics: Azathioprine; Crossing Over, Genetic; Humans; Immunosuppression Therapy; Kidney Transplantation; Lym | 1983 |
[Cutaneous nodular Kaposi sarcoma following kidney transplantation and immunosuppression].
Topics: Adult; Azathioprine; Female; Humans; Immunosuppression Therapy; Kidney Failure, Chronic; Leukocyte C | 1984 |
Aggressive squamous cell carcinomas in organ transplant recipients.
Topics: Azathioprine; Carcinoma, Squamous Cell; Cyclosporine; Heart Transplantation; Humans; Immunosuppressi | 1995 |
Recurrent lymphoma in a cardiac allograft recipient.
Topics: Azathioprine; Cyclosporine; Follow-Up Studies; Graft Rejection; Heart Transplantation; Humans; Lung | 1994 |
Paraneoplastic pemphigus in a patient with non-Hodgkin's lymphoma.
Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined Modality Thera | 1996 |
Late onset immunodeficiency in a patient with recurrent thymic carcinoma and myasthenia gravis.
Topics: Adult; Age Factors; Azathioprine; Carcinoma; CD4-Positive T-Lymphocytes; Female; Humans; Immunologic | 1998 |
Cardiac transplant-related cutaneous malignancies in an Australian recipient: immunosuppression, friend or foe?
Topics: Adult; Australia; Azathioprine; Bowen's Disease; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cy | 1998 |
Decreased rate of growth of hepatocellular carcinoma recurrence after liver transplantation in patients maintained on cyclosporine immunosuppression.
Topics: Azathioprine; Carcinoma, Hepatocellular; Cyclosporins; Humans; Liver Neoplasms; Liver Transplantatio | 1988 |
[Examples for possible tumor induction by immunosuppressive and cytostatic drugs (case studies)].
Topics: Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Combined | 1986 |
Serum -fetoprotein in hepatoma patients after liver transplantation.
Topics: Adolescent; Adult; Alanine Transaminase; Alpha-Globulins; Aspartate Aminotransferases; Autopsy; Azat | 1971 |
Florid keratoacanthomas in a kidney transplant recipient. Case report.
Topics: Azathioprine; Carcinoma, Squamous Cell; Dactinomycin; Graft Rejection; Humans; Immunosuppression The | 1974 |
Attempted induction of sarcoma in a Cape Chacma baboon with the Snyder-Theilen feline sarcoma virus.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Cats; Fibrosarcoma; Haplorhini; Immunity; Male; Neoplas | 1973 |
Antimitotic drugs and aggressive squamous cell tumors.
Topics: Aged; Antineoplastic Agents; Azathioprine; Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Kerat | 1972 |