Page last updated: 2024-10-23

azathioprine and Liver Diseases

azathioprine has been researched along with Liver Diseases in 167 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Liver Diseases: Pathological processes of the LIVER.

Research Excerpts

ExcerptRelevanceReference
"Within one year three of 25 patients with rheumatoid arthritis treated with azathioprine 100 mg daily developed the following adverse reactions less than two weeks after starting treatment: patient one showed fever with chills, rash, and severe liver function abnormalities suggestive of cholestasis; the second patient had fever, nausea, diarrhoea, and moderately raised liver enzymes; the third patient showed very high fever and severe chills."7.68Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. ( Boerbooms, AM; Jeurissen, ME; Kruijsen, MW; van de Putte, LB, 1990)
"Immunosuppressive treatment with prednisolone and/or azathioprine has been assessed in three chronic liver diseases with immunological features, namely chronic active hepatitis, cryptogenic cirrhosis and primary biliary cirrhosis."5.04Immunosuppressive therapy in chronic liver disease. ( Sherlock, S, 1978)
" The variety of acute hepatitis include hepatitis A, hepatitis B, cytomegalovirus hepatitis, herpes simplex hepatitis and azathioprine hepatitis."4.75Liver disease in renal transplant recipients. ( Anuras, S; Sopko, J, 1978)
" Acute cholestasis is one of the most common forms of hepatotoxicity induced by azathioprine."4.12Severe azathioprine-induced liver injury 22 months after initiation of treatment. ( Battezzati, PM; Cataletti, G; Pastorelli, L; Santagata, F, 2022)
"Within one year three of 25 patients with rheumatoid arthritis treated with azathioprine 100 mg daily developed the following adverse reactions less than two weeks after starting treatment: patient one showed fever with chills, rash, and severe liver function abnormalities suggestive of cholestasis; the second patient had fever, nausea, diarrhoea, and moderately raised liver enzymes; the third patient showed very high fever and severe chills."3.68Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. ( Boerbooms, AM; Jeurissen, ME; Kruijsen, MW; van de Putte, LB, 1990)
"Three cases of azathioprine-induced complex of liver diseases are described, and their light microscopy and ultrastructural findings are detailed."3.67Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations. ( Ackrill, P; Ali, HH; Haboubi, NY; Whitwell, HL, 1988)
"Serum squalene levels did not change in patients with acute hepatitis, chronic active hepatitis and liver cirrhosis, but were significantly reduced in patients with intra- and extrahepatic cholestasis."3.66Serum squalene levels in hepatobiliary diseases. ( Hirayama, C; Ikawa, S; Yamanishi, Y, 1978)
"Autoimmune liver diseases (autoimmune hepatitis, primary sclerosing cholangitis, overlap syndrome) can occur in the setting of limited symptoms; therefore, a high index of suspicion and appropriate diagnostic workup should be performed."2.72Pediatric Autoimmune Liver Diseases: Autoimmune Hepatitis and Primary Sclerosing Cholangitis. ( Kemme, S; Mack, CL, 2021)
" Drug adverse effects and the lack of efficacy, however, commonly require withdrawal of therapy."2.44Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol. ( Gearry, RB; Leong, RW; Sparrow, MP, 2008)
"Autoimmune Hepatitis (AIH), primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC) and overlap syndromes of these three disease entities are regarded as autoimmune liver diseases."2.42[Autoimmune liver disease: diagnosis and therapy]. ( Bayer, EM; Kanzler, S; Lohse, AW; Schramm, C, 2004)
"The diagnosis and management of autoimmune hepatitis continues to evolve as new diagnostic tests and new therapies are added to the armamentarium."2.41Autoimmune liver disease. Current standards, future directions. ( Gish, RG; Mason, A, 2001)
"Dengue is a proven risk factor for many autoimmune conditions but its association with AIH is not studied."1.91Autoimmune hepatitis unmasked by dengue infection - An unexplored and rare association. ( Chaitanya, V; Jagtap, AB; Lall, B; Porwal, YC; S, C, 2023)
"Autoimmune hepatitis is a rare but chronic autoimmune-mediated liver disease."1.72[Autoimmune Hepatitis - What is important for clinical practice?] ( Böttler, T; Thimme, R; Vogelbacher, L, 2022)
"Autoimmune hepatitis is a relatively rare disease that may lead to rapidly progressing liver cirrhosis and even fulminant liver failure, if diagnosis and treatment is delayed or ineffective."1.38[Characteristics, diagnosis and therapy of patients with autoimmune hepatitis]. ( Larsen, FS; Ytting, H, 2012)
"Azathioprine (Aza) is an important drug commonly used in the therapy of autoimmune system disorders."1.36Grape seed extract prevents azathioprine toxicity in rats. ( El-Ashmawy, IM; Gad, SB; Salama, OM, 2010)
"Azathioprine (AZA) is an important drug used in the therapy of autoimmune system disorders."1.32A comparison of hepatoprotective activities of aminoguanidine and N-acetylcysteine in rat against the toxic damage induced by azathioprine. ( Ahmad, M; Al-Shabanah, OA; Gado, A; Raza, M, 2003)
"Azathioprine was discontinued."1.27Favourable outcome of hepatic veno-occlusive disease in a renal transplant patient receiving azathioprine, treated by portacaval shunt. Report of a case and review of the literature. ( Creutzfeldt, W; Eisenhauer, T; Hartmann, H; Helmchen, U; Rumpf, KW; Scheler, F, 1984)
"Peliosis hepatis is described in a renal transplant recipient and in a patient who was receiving long-term haemodialysis."1.27Peliosis hepatis in a renal transplant recipient and in a haemodialysis patient. ( Hankey, GJ; Saker, BM, 1987)
" These observations strongly suggest an association between chronic use of azathioprine and the development of venous congestion of the liver with sinusoidal dilatation, eventually resulting in chronic liver disease."1.27Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment after kidney transplantation. ( Assmann, KM; Deckers, PF; Driessen, WM; Gerlag, PG; Lobatto, S; Schröder, E; Van Haelst, UJ; Van Hooff, JP, 1985)
"Subsequent courses of treatment after relapse were equally effective in again inducing remission, but the probability of another relapse increased after each successive therapy and was 86% after three treatments."1.26Clinical features and prognosis of severe chronic active liver disease (CALD) after corticosteroid-induced remission. ( Ammon, HV; Czaja, AJ; Summerskill, WH, 1980)
"Azathioprine was responsible for some episodes of acute cholestasis but could not be incriminated as a direct cause of chronic disease."1.26Etiology of liver disease in renal-transplant patients. ( Atkins, CR; Combes, B; Cuthbert, JA; Eigenbrodt, EH; Hollinger, B; Hull, AR; Luby, JP; Shorey, J; Ware, AJ, 1979)

Research

Studies (167)

TimeframeStudies, this research(%)All Research%
pre-1990120 (71.86)18.7374
1990's18 (10.78)18.2507
2000's14 (8.38)29.6817
2010's11 (6.59)24.3611
2020's4 (2.40)2.80

Authors

AuthorsStudies
Kemme, S1
Mack, CL1
Vogelbacher, L1
Thimme, R1
Böttler, T1
Jagtap, AB1
S, C1
Chaitanya, V1
Lall, B1
Porwal, YC1
Cataletti, G1
Santagata, F1
Pastorelli, L1
Battezzati, PM1
Mavilia, M1
McAuliffe, A1
Hafeez, S1
Vaziri, H1
Simsek, M1
Meijer, B1
Ramsoekh, D1
Bouma, G1
van der Wouden, EJ1
den Hartog, B1
de Vries, AC1
Hoentjen, F1
Dijkstra, G1
de Boer, SY1
Jansen, JM1
van der Meulen, AE1
Beukers, R1
Brink, MA1
Steinhauser, T1
Oldenburg, B1
Gilissen, LP2
Naber, TH1
Verhagen, MA1
de Boer, NKH1
Mulder, CJJ1
Aljumah, AA1
Al Jarallah, B1
Albenmousa, A1
Al Khathlan, A1
Al Zanbagi, A1
Al Quaiz, M1
Al-Judaibi, B1
Nabrawi, K1
Al Hamoudi, W1
Alghamdi, M1
Fallatah, H1
Silva, J1
Brito, BS1
Silva, INN1
Nóbrega, VG1
da Silva, MCSM1
Gomes, HDN1
Fortes, FM1
Pimentel, AM1
Mota, J1
Almeida, N1
Surlo, VC1
Lyra, A1
Rocha, R1
Santana, GO1
Vo, HD1
Xu, J1
Rabinowitz, SS1
Fisher, SE1
Schwarz, SM1
Liu, Y1
Yu, J1
Oaks, Z1
Marchena-Mendez, I1
Francis, L1
Bonilla, E1
Aleksiejuk, P1
Patel, J1
Banki, K1
Landas, SK1
Perl, A1
Eichenberger, A1
Buechi, AE1
Neumayr, A1
Hatz, C1
Rauch, A1
Huguenot, M1
Diamantis-Karamitopoulou, E1
Staehelin, C1
Leong, RW1
Gearry, RB1
Sparrow, MP1
Malhotra, A1
Naniwadekar, A1
Sood, G1
Takatsu, N1
Matsui, T1
Murakami, Y1
Ishihara, H1
Hisabe, T1
Nagahama, T1
Maki, S1
Beppu, T1
Takaki, Y1
Hirai, F1
Yao, K1
El-Ashmawy, IM1
Gad, SB1
Salama, OM1
Mosea, H1
Gotto, J1
Khan, Z1
Chan, AJ1
Lake, JR1
Ytting, H1
Larsen, FS1
Taylor, RM1
Cheeseman, P1
Rela, M1
Heaton, N1
Mieli-Vergani, G1
Dhawan, A1
Raza, M1
Ahmad, M1
Gado, A1
Al-Shabanah, OA1
MATHE, G1
AMIEL, JL1
SCHWARZENBERG, L1
CATTAN, A1
SCHNEIDER, M1
DEVRIES, MJ1
TUBIANA, M1
LALANNE, C1
BINET, JL1
PAPIERNIK, M1
SEMAN, G1
MATSUKURA, M1
MERY, AM1
SCHWARZMANN, V1
FLAISLER, A1
GLIEDMAN, ML2
PANGAN, J1
MINKOWITZ, S1
POPOWITZ, L1
KARLSON, KE1
Bayer, EM1
Schramm, C1
Kanzler, S1
Lohse, AW1
Kerkar, N1
Dugan, C1
Rumbo, C1
Morotti, RA1
Gondolesi, G1
Shneider, BL1
Emre, S1
Bastida, G1
Nos, P1
Aguas, M1
Beltrán, B1
Rubín, A1
Dasí, F1
Ponce, J1
Maier, KP1
Derijks, LJ1
de Boer, NK1
Mulder, CJ1
Strassburg, CP1
Gisbert, JP1
González-Lama, Y1
Maté, J1
Camilleri, M1
Saito, YA1
Teruel, JL1
Marcén, R1
Celma, ML1
Bueno, R1
Jiménez del Cerro, L1
Matesanz, R1
Quereda, C1
Ortuño, J1
Rull, S1
Rodríguez-San Román, JL1
Velilla, JP1
Campos, H1
Kreis, HA1
Rioux, P1
Crosnier, J1
Eisenhauer, T1
Hartmann, H1
Rumpf, KW1
Helmchen, U1
Scheler, F1
Creutzfeldt, W1
Nanji, AA1
Obata, T1
Watanabe, A2
Hayashi, S1
Higashi, T1
Endo, H1
Nagashima, H2
Horimi, T1
Huchimoto, S1
Sakagami, K1
Orita, K1
Becker, K1
Ozaki, A1
Iwasaki, Y1
Miyajima, T1
Toledo-Pereyra, LH1
Gordon, DA1
MacKenzie, GH1
Boroń, P1
Szpakowicz, T1
Bobrowska, E1
Boroń-Kaczmarska, A1
Prokopowicz, D1
Borzuchowska, A1
Czaja, AJ2
Ammon, HV3
Summerskill, WH11
Bismuth, H1
Punch, JD1
Shieck, VL1
Campbell, DA1
Bromberg, JS1
Turcotte, JG1
Merion, RM1
Elariny, HA1
Mizrahi, SS1
Hayes, DH1
Boudreaux, JP1
Hussey, JL1
Farr, GH1
Jazzar, A1
Fagiuoli, S1
Caraceni, P1
Deal, S1
Wright, HI1
Sisson, S1
Gavaler, J1
Van Thiel, DH1
Zuhdi, N1
Cooper, DK1
Tisone, G1
Vennarecci, G1
Pisani, F1
Pieragostini, E1
Alciati, E1
Casciani, CU1
Seiler, CA1
Renner, EL1
Horber, F1
Rieder, H1
Reichen, J1
Czerniak, A1
Konstantinov, BA1
Eramishantsev, AK1
Goté, SV1
Tsirulńikova, OM1
Skipenko, OG1
Lebezev, VM1
Shertsinger, AG1
Lokshin, LS1
Pons, JA1
Bueno, F1
Parrilla, P1
Ramirez, P1
Bixquert, V1
Robles, R1
Miras, M1
Rodriguez, J1
Schattenfroh, N1
Lange, D1
Bechstein, WO2
Blumhardt, G1
Lohmann, R1
Neuhaus, P2
Farrell, GC1
Lang, M1
Kahl, A1
Neumann, U1
Settmacher, U1
Frei, U1
Honoré, P1
Detry, O1
Meurisse, M1
Jacquet, N1
Gish, RG1
Mason, A1
Köttgen, E2
Gerok, W3
Prellwitz, W1
Hobara, N1
Ware, AJ2
Luby, JP2
Eigenbrodt, EH2
Long, DL1
Hull, AR2
Berne, TV2
Chatterjee, SN1
Craig, JR1
Payne, JE1
Sopko, J1
Anuras, S1
Mozes, MF1
Ascher, NL1
Balfour, HH1
Simmons, RL1
Najarian, JS1
Hollinger, B1
Cuthbert, JA1
Atkins, CR1
Shorey, J1
Combes, B1
Starzl, TE6
Powell, LW2
Tolman, KG1
Butler, J1
Silberman, H1
Whitcomb, FF1
Magnenat, P1
Galizzi, J1
Long, RG1
Billing, BH1
Sherlock, S4
Yamanishi, Y1
Ikawa, S1
Hirayama, C1
Schalm, SW2
Gitnick, GL2
Elveback, LR2
Podymova, SD1
Nasonov, EL1
Braun, HH1
Henning, H1
Probst, P1
Geubel, AP1
Baggenstoss, AH3
Torisu, M2
Yoshida, T1
Cohen, S1
Marubbio, AT1
Danielson, B1
Korman, MG1
Rikkers, L1
Toth, IG1
Shorter, RG1
Shephard, DA1
Sharma, RK1
Elhence, R1
Kher, V1
Naik, SR1
Bhandari, M1
Takeuchi, N1
Ohshima, S1
Ono, Y1
Sahashi, M1
Matsuura, O1
Yamada, S1
Tanaka, K1
Kuriki, O1
Kamihira, O1
Aroldi, A1
Tarantino, A1
Montagnino, G1
Paparella, M1
Cesana, B1
Rumi, MG1
Ponticelli, C1
Cames, B1
Rahier, J1
Burtomboy, G1
de Ville de Goyet, J1
Reding, R1
Lamy, M1
Otte, JB1
Sokal, EM1
Jeurissen, ME1
Boerbooms, AM1
van de Putte, LB1
Kruijsen, MW1
Moreno, F1
Morales, JM1
Colina, F1
Prieto, C1
Andrés, A1
Alcázar, JM1
Hernandez, E1
Castellanos, G1
Rodicio, JL1
Kaplan, MM1
Krom, RA1
Wiesner, RH1
Haagsma, EB1
Ludwig, J1
Gips, CH1
Grond, AJ1
Houthoff, HJ1
Haboubi, NY1
Ali, HH1
Whitwell, HL1
Ackrill, P1
García Buey, L1
Moreno Otero, R1
García Sánchez, A1
González Estecha, A1
Pajares, JM1
Oka, T1
Omori, Y1
Aikawa, I1
Yasumura, T1
Yoshimura, N1
Nakai, I1
Gerlag, PG2
van Hooff, JP2
Katzka, DA1
Saul, SH1
Jorkasky, D1
Sigal, H1
Reynolds, JC1
Soloway, RD5
Hankey, GJ1
Saker, BM1
Takahara, S1
Ihara, H1
Ichikawa, Y1
Nagano, S1
Fukunishi, T1
Sonoda, T1
Shinji, Y1
Cooper, C1
Cotton, DW1
Minihane, N1
Cawley, MI1
Lobatto, S1
Driessen, WM1
Deckers, PF1
Schröder, E1
Assmann, KM1
Van Haelst, UJ1
Perlmutter, D1
Vacanti, J1
Donahoe, P1
Kleinman, R1
Weir, MR1
Kirkman, RL1
Strom, TB1
Tilney, NL1
Andres, GA1
Ansell, ID1
Halgrimson, CG2
Hsu, KC1
Porter, KA3
Accinni, L1
Calne, RY1
Herbertson, BM1
Penn, I4
Rendall, JM1
Williams, R5
Delespesse, G1
Kennes, B1
Duchateau, J1
Mitchell, CG2
Eddleston, AL3
Smith, MG3
Ritman, S1
Schoenfield, LJ4
Wildhirt, E1
Jensen, KB2
Jarnum, S1
Ranek, L1
Westergaard, H1
Fulginiti, VA1
Scribner, R1
Groth, CG2
Putnam, CW4
Brettschneider, L3
Gilbert, S1
Bell, P2
McGuire, RL1
Blanchard, H1
Kashiwagi, N1
Pagaltsos, AP1
Nicolaescu, T4
Bittman, E4
Stoiculescu, P4
Bordeianu, A4
Ciontescu, L3
Fine, RN1
Slavin, S1
Zlotnick, A1
Levij, IS1
Eliakim, M1
Pirson, Y1
van Ypersele de Strihou, C1
Noel, H1
Alexandre, GP1
Troch, R1
Fung, WP1
Barzilai, DC1
Mörl, M1
Chandler, JG1
Villar, H1
Lee, S1
Williams, RJ1
Nakaji, NT1
Ferrebee, JW1
Orloff, MJ1
Zarday, Z1
Veith, FJ1
Soberman, R1
Thomson, TJ1
Bach, JF2
Dardenne, M2
Klatskin, G1
Kantor, FS1
Ross, RC1
Kovacs, K1
Horvath, E1
Ireland, P1
Rashid, A1
von Lichtenberg, F1
Cavallo, T1
Merrill, JP1
Murray-Lyon, IM1
Lesesne, HR1
Fallon, HJ1
Black, M1
Rosenoer, VM1
Gokim, G1
Axelsen, E1
Whelan, G1
Javett, SL1
Kavin, H1
Bremner, CG1
Schneider, J1
Levine, E1
Hinder, RA1
Renger, F1
Dökert, B1
Bauch, K1
Büttner, W1
Lewicki, I1
Zimmermann, S1
Dempe, A1
Bär, U1
Becker, H1
May, B1
Mayer, D1
Ohlendorf, S1
Otto, P1
Schmidt, FW1
Gheorghe, N1
Pintilescu, V1
Metz, L1
Nicolescu, T1
Boroş, I1
Jinga, V1
Moucha, R1
Salerno, F1
Tornaghi, G1
Cappellini, MD1
Fargion, S1
Fiorelli, G1
MacSween, RN1
Mistilis, SP1
Blackburn, CR1
Eiseman, B1
Eales, L1
Grosser, Y1
Levey, M1
Rogers, AI1
Franksson, C1
Thiel, G1
Yokoyama, T1
Amemiya, H1
Kohler, PF1
Schroter, G1
Martineau, G1
Palmer, W1
Golding, PL1
Kemp, A1
Elion, GB1
Caravati, CM1
Hooker, TH1
Brodanová, M1
Filip, J1
Kleine, FD1
Keitel, W1
Franke, A1
Deitcher, KA1
Trey, C1
Aprosina, ZG1
Mukhin, AS1
Schulz, K1
Preussner, S1
Frick, G1
Frankel, HH1
Yamamoto, RS1
Weisburger, EK1
Weisburger, JH1
Gerhartz, H1
Geall, MG1
De Groote, J1
Vandenbroucke, J1
Maes, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prophylactic Infusion of Donor Lymphocytes in Cord Blood Transplantation[NCT02328885]Phase 1/Phase 217 participants (Actual)Interventional2014-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

29 reviews available for azathioprine and Liver Diseases

ArticleYear
Pediatric Autoimmune Liver Diseases: Autoimmune Hepatitis and Primary Sclerosing Cholangitis.
    Pediatric clinics of North America, 2021, Volume: 68, Issue:6

    Topics: Adolescent; Asymptomatic Diseases; Autoimmune Diseases; Azathioprine; Biomarkers; Child; Cholangitis

2021
The liver in pediatric gastrointestinal disease.
    Journal of pediatric gastroenterology and nutrition, 2014, Volume: 59, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal; Azathioprine; Celiac Disease; Chemical and Drug Induced Liver In

2014
Thiopurine hepatotoxicity in inflammatory bowel disease: the role for adding allopurinol.
    Expert opinion on drug safety, 2008, Volume: 7, Issue:5

    Topics: Allopurinol; Azathioprine; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug;

2008
Immunosuppression in HCV-positive liver-transplant recipients.
    Current opinion in organ transplantation, 2012, Volume: 17, Issue:6

    Topics: Adrenal Cortex Hormones; Alemtuzumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Ant

2012
[Autoimmune liver disease: diagnosis and therapy].
    Zeitschrift fur Gastroenterologie, 2004, Volume: 42, Issue:1

    Topics: Adult; Autoantibodies; Autoimmune Diseases; Azathioprine; Biopsy; Child; Cholagogues and Choleretics

2004
[Drug therapy in chronic liver disease].
    Praxis, 2005, Nov-30, Volume: 94, Issue:48

    Topics: Adenine; Administration, Oral; Anti-HIV Agents; Antiviral Agents; Azathioprine; Cholangitis, Scleros

2005
[Autoimmune liver diseases and their overlap syndromes].
    Praxis, 2006, Sep-06, Volume: 95, Issue:36

    Topics: Adult; Anti-Inflammatory Agents; Antibodies, Antinuclear; Autoantibodies; Autoimmune Diseases; Azath

2006
Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:7

    Topics: Antimetabolites, Antineoplastic; Azathioprine; Chemical and Drug Induced Liver Injury; Global Health

2007
Pharmacogenomics in gastrointestinal disorders.
    Methods in molecular biology (Clifton, N.J.), 2008, Volume: 448

    Topics: Antineoplastic Agents; Azathioprine; Biotransformation; Colorectal Neoplasms; Gastrointestinal Agent

2008
[Current aspects of primary biliary cirrhosis (2)].
    Revista espanola de las enfermedades del aparato digestivo, 1983, Volume: 64, Issue:5

    Topics: Azathioprine; Biliary Tract Diseases; Cholestyramine Resin; Cyclosporins; Diagnosis, Differential; H

1983
[Long-term prognosis in chronic liver diseases].
    Wiener medizinische Wochenschrift (1946), 1980, Sep-15, Volume: 130, Issue:17

    Topics: Alcoholism; Azathioprine; Cortisone; Fatty Liver; Hepatitis; Humans; Liver Cirrhosis; Liver Cirrhosi

1980
Nodular regenerative hyperplasia: a controversial indication for orthotopic liver transplantation.
    Transplant international : official journal of the European Society for Organ Transplantation, 1994, Volume: 7, Issue:4

    Topics: Adult; Azathioprine; Female; Humans; Hyperplasia; Hypertension, Portal; Kidney Transplantation; Live

1994
Drug-induced hepatic injury.
    Journal of gastroenterology and hepatology, 1997, Volume: 12, Issue:9-10

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimetabolites, Antineoplastic; Aza

1997
Autoimmune liver disease. Current standards, future directions.
    Clinics in liver disease, 2001, Volume: 5, Issue:2

    Topics: Anti-Inflammatory Agents; Autoimmune Diseases; Azathioprine; Cholagogues and Choleretics; Cholangiti

2001
Liver disease in renal transplant recipients.
    The American journal of medicine, 1978, Volume: 64, Issue:1

    Topics: Animals; Azathioprine; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Cholestasis; Ch

1978
Treatment of inflammatory and metal storage diseases of the liver.
    Clinics in gastroenterology, 1979, Volume: 8, Issue:1

    Topics: Adrenal Cortex Hormones; Azathioprine; Bloodletting; Chelating Agents; Chronic Disease; Copper; Fema

1979
[Immunodepressants in chronic liver diseases (a review of the literature and the authors' own data)].
    Terapevticheskii arkhiv, 1976, Volume: 48, Issue:3

    Topics: Azathioprine; B-Lymphocytes; Chronic Disease; Denmark; Drug Evaluation; Female; Glucocorticoids; Hep

1976
[Liver disease caused by azathioprine: clinical case and review of the literature].
    Revista espanola de las enfermedades del aparato digestivo, 1988, Volume: 73, Issue:2

    Topics: Aged; Azathioprine; Chemical and Drug Induced Liver Injury; Humans; Leukopenia; Liver Diseases; Male

1988
Liver transplantation in pediatric patients.
    Advances in pediatrics, 1985, Volume: 32

    Topics: Antilymphocyte Serum; Azathioprine; Bile Ducts; Child; Cyclosporins; Glucocorticoids; Graft Rejectio

1985
[Auto-immune diseases and immunodepressive therapy. II. Current clinical indications].
    Acta clinica Belgica, 1974, Volume: 29, Issue:6

    Topics: Adrenal Cortex Hormones; Anemia, Hemolytic, Autoimmune; Antineoplastic Agents; Arteritis; Autoimmune

1974
Advances in gastroenterology.
    The Practitioner, 1972, Volume: 209, Issue:252

    Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Colitis, Ulcerative; Diet; Disaccharides; Du

1972
IgM turnover in man.
    Ciba Foundation symposium, 1972, Volume: 9

    Topics: Abscess; Adult; Azathioprine; Celiac Disease; Chronic Disease; Clone Cells; Crohn Disease; Feces; Ga

1972
Immunosuppressive therapy for chronic liver disease.
    Journal of the Royal College of Physicians of London, 1973, Volume: 8, Issue:1

    Topics: Anti-Inflammatory Agents; Antibody Formation; Autoantibodies; Autoimmune Diseases; Azathioprine; Chr

1973
Treatment of liver disease with corticosteroids.
    The Medical clinics of North America, 1973, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Glucocort

1973
Liver disease and drug therapy.
    The Medical clinics of North America, 1974, Volume: 58, Issue:5

    Topics: Amobarbital; Azathioprine; Half-Life; Humans; Lidocaine; Liver Cirrhosis; Liver Diseases; Metabolic

1974
Management of patients with chronic obstructive jaundice.
    The Medical clinics of North America, 1972, Volume: 56, Issue:3

    Topics: Adrenal Cortex Hormones; Azathioprine; Bile Acids and Salts; Cholestasis; Chronic Disease; Diet Ther

1972
Active chronic hepatitis.
    The American journal of medicine, 1970, Volume: 48, Issue:4

    Topics: Adrenal Cortex Hormones; Azathioprine; Chronic Disease; Diagnosis, Differential; False Positive Reac

1970
Therapeutic considerations in selected forms of acute and chronic liver disease.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Acute Disease; Age Factors; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Chroni

1971
[Liver transplantation in humans].
    Schweizerische medizinische Wochenschrift, 1970, Jan-31, Volume: 100, Issue:5

    Topics: Antilymphocyte Serum; Azathioprine; Biliary Tract Diseases; Graft Rejection; Hepatectomy; Histocompa

1970

Trials

18 trials available for azathioprine and Liver Diseases

ArticleYear
[Immunosuppressive treatment of chronic liver diseases in the clinical biochemical, immunological and histological evaluation of the liver].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, May-15, Volume: 36, Issue:10

    Topics: Adolescent; Adult; Aged; Azathioprine; Bilirubin; Chronic Disease; Drug Therapy, Combination; Female

1981
Comparison of FK 506- and cyclosporine-based immunosuppression: FK 506 therapy significantly reduces the incidence of acute, steroid-resistant, refractory, and chronic rejection whilst possessing a comparable safety profile. European FK 506 Multicenter Li
    Transplantation proceedings, 1995, Volume: 27, Issue:1

    Topics: Antilymphocyte Serum; Azathioprine; Cyclosporine; Drug Resistance; Drug Therapy, Combination; Female

1995
Corticosteroid withdrawal after liver transplantation.
    Surgery, 1995, Volume: 118, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Azathioprine; Cyclosporine; Diabetes Mellitus,

1995
Incidence and etiology of hepatic dysfunction in heart transplant recipients receiving a cyclosporine-based triple immunosuppressive therapy.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Cyclosporine; Drug Therapy, Combination; Follo

1994
Cyclosporine A monitoring in liver transplant.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Antibodies, Monoclonal; Azathioprine; Biopsy, Needle; Cyclosporine; Drug Monitoring; Drug Therapy, C

1994
Cyclosporine vs OKT3 prophylaxis after orthotopic liver transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:2

    Topics: Adult; Azathioprine; Bilirubin; Creatinine; Cyclosporine; Drug Therapy, Combination; Follow-Up Studi

1993
Quadruple-drug therapy with antithymocyte globulin in the early postoperative period after liver transplantation.
    Transplantation proceedings, 1993, Volume: 25, Issue:2

    Topics: Actuarial Analysis; Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Drug Therapy, Combinati

1993
Immunosuppressive therapy in chronic liver disease.
    Minerva medica, 1978, Aug-18, Volume: 69, Issue:38

    Topics: Azathioprine; Chronic Disease; Drug Therapy, Combination; Hepatitis; Hepatitis B; Hepatitis B Surfac

1978
Failure of customary treatment in chronic active liver disease: causes and management.
    Annals of clinical research, 1976, Volume: 8, Issue:3

    Topics: Azathioprine; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Evaluation Studi

1976
Contrasting features and responses to treatment of severe chronic active liver disease with and without hepatitis BS antigen.
    Gut, 1976, Volume: 17, Issue:10

    Topics: Adult; Age Factors; Azathioprine; Chronic Disease; Clinical Trials as Topic; Female; Hepatitis; Hepa

1976
Prednisone for chronic active liver disease: dose titration, standard dose, and combination with azathioprine compared.
    Gut, 1975, Volume: 16, Issue:11

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Chronic Disease; Clinical Trials as Topic; Drug Therap

1975
Influence of long-term cyclosporine therapy on chronic liver disease after renal transplantation.
    Transplantation proceedings, 1990, Volume: 22, Issue:5

    Topics: Azathioprine; Chronic Disease; Cyclosporins; Follow-Up Studies; Humans; Immunosuppression Therapy; K

1990
A comparison of azathioprine and cyclosporine in liver transplantation: a study of two personal series.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 3

    Topics: Adult; Alkaline Phosphatase; Azathioprine; Bilirubin; Clinical Trials as Topic; Creatinine; Cyclospo

1987
Anticomplementary hepatitis B antigen. Prognostic importance in chronic active liver disease.
    Archives of internal medicine, 1973, Volume: 132, Issue:4

    Topics: Antibodies; Azathioprine; Chronic Disease; Complement Fixation Tests; Drug Synergism; Hepatitis B An

1973
Infections in recipients of liver homografts.
    The New England journal of medicine, 1968, Sep-19, Volume: 279, Issue:12

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Azathioprine; Candida; Cytomegalovirus; Enterobacter

1968
Circulating thyroxine in chronic active liver disease.
    Israel journal of medical sciences, 1974, Volume: 10, Issue:11

    Topics: Adolescent; Adult; Aged; Azathioprine; Chronic Disease; Drug Therapy, Combination; Female; Humans; L

1974
Chronic active liver disease. The range of histologic lesions, their response to treatment, and evolution.
    Human pathology, 1972, Volume: 3, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Autopsy; Azathioprine; Biopsy; Cholangitis; Chronic Disease;

1972
Classification and treatment of chronic active liver disease.
    Gastroenterology, 1968, Volume: 55, Issue:6

    Topics: Azathioprine; Cholestasis; Chronic Disease; Female; Hepatitis; Humans; Liver; Liver Cirrhosis; Liver

1968

Other Studies

120 other studies available for azathioprine and Liver Diseases

ArticleYear
[Autoimmune Hepatitis - What is important for clinical practice?]
    Deutsche medizinische Wochenschrift (1946), 2022, Volume: 147, Issue:8

    Topics: Autoantibodies; Azathioprine; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunosuppressive Agen

2022
Autoimmune hepatitis unmasked by dengue infection - An unexplored and rare association.
    Tropical doctor, 2023, Volume: 53, Issue:1

    Topics: Azathioprine; Dengue; Female; Hepatitis, Autoimmune; Humans; Liver Diseases

2023
Severe azathioprine-induced liver injury 22 months after initiation of treatment.
    BMJ case reports, 2022, Dec-21, Volume: 15, Issue:12

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chroni

2022
Hepatosplenic T cell lymphoma: a unifying entity in a patient with hemolytic anemia, massive splenomegaly, and liver dysfunction.
    Clinical journal of gastroenterology, 2018, Volume: 11, Issue:5

    Topics: Adult; Anemia, Hemolytic; Azathioprine; Biopsy; Chronic Disease; Colitis, Ulcerative; Fatal Outcome;

2018
Clinical Course of Nodular Regenerative Hyperplasia in Thiopurine Treated Inflammatory Bowel Disease Patients.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2019, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Female; Humans; Hyperplasia; Inflammatory Bowel Diseases; Liv

2019
The Saudi association for the study of liver diseases and transplantation clinical practice guidelines for management of autoimmune hepatitis.
    Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association, 2018, Volume: 24, Issue:7 Suppl

    Topics: Adult; Azathioprine; Female; Fibrosis; Hepatitis, Autoimmune; Humans; Immunosuppressive Agents; Live

2018
Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients.
    BioMed research international, 2019, Volume: 2019

    Topics: Adult; Azathioprine; Cholelithiasis; Colitis, Ulcerative; Crohn Disease; Cross-Sectional Studies; Fe

2019
Liver injury correlates with biomarkers of autoimmunity and disease activity and represents an organ system involvement in patients with systemic lupus erythematosus.
    Clinical immunology (Orlando, Fla.), 2015, Volume: 160, Issue:2

    Topics: Acetylcysteine; Adult; Alanine Transaminase; Antibodies, Antinuclear; Aspartate Aminotransferases; A

2015
A severe case of visceral leishmaniasis and liposomal amphotericin B treatment failure in an immunosuppressed patient 15 years after exposure.
    BMC infectious diseases, 2017, 01-17, Volume: 17, Issue:1

    Topics: Aged, 80 and over; Amphotericin B; Antiprotozoal Agents; Azathioprine; Biopsy; Colon; Europe; Humans

2017
Hepatobiliary and pancreatic: cirrhosis secondary to hepatic sarcoidosis.
    Journal of gastroenterology and hepatology, 2008, Volume: 23, Issue:12

    Topics: Adult; Azathioprine; Biopsy; Humans; Immunosuppressive Agents; Liver Cirrhosis; Liver Diseases; Live

2008
Adverse reactions to azathioprine cannot be predicted by thiopurine S-methyltransferase genotype in Japanese patients with inflammatory bowel disease.
    Journal of gastroenterology and hepatology, 2009, Volume: 24, Issue:7

    Topics: Adult; Alopecia; Aminosalicylic Acids; Anti-Inflammatory Agents; Asian People; Azathioprine; Chemica

2009
Grape seed extract prevents azathioprine toxicity in rats.
    Phytotherapy research : PTR, 2010, Volume: 24, Issue:11

    Topics: Animals; Antioxidants; Azathioprine; Folic Acid; Glutathione; Grape Seed Extract; Lipid Peroxidation

2010
Diagnostic and therapeutic challenges of hepatic sarcoidosis.
    BMJ case reports, 2011, Jul-15, Volume: 2011

    Topics: Adult; Aged; Azathioprine; Biopsy; Diagnosis, Differential; Diagnostic Imaging; Female; Gastroscopy;

2011
[Characteristics, diagnosis and therapy of patients with autoimmune hepatitis].
    Ugeskrift for laeger, 2012, Nov-12, Volume: 174, Issue:46

    Topics: Anti-Inflammatory Agents; Azathioprine; Delayed Diagnosis; Hepatitis, Autoimmune; Humans; Immunosupp

2012
Use of calcineurin inhibitors in pediatric liver transplantation: a single-center experience.
    Transplantation proceedings, 2002, Volume: 34, Issue:5

    Topics: Adolescent; Azathioprine; Calcineurin Inhibitors; Child; Child, Preschool; Cyclosporine; Enzyme Inhi

2002
A comparison of hepatoprotective activities of aminoguanidine and N-acetylcysteine in rat against the toxic damage induced by azathioprine.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2003, Volume: 134, Issue:4

    Topics: Acetylcysteine; Animals; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Therapy, Combina

2003
SUCCESSFUL ALLOGENIC BONE MARROW TRANSPLANTATION IN MAN: CHIMERISM, INDUCED SPECIFIC TOLERANCE AND POSSIBLE ANTI-LEUKEMIC EFFECTS.
    Blood, 1965, Volume: 25

    Topics: Antineoplastic Agents; Azathioprine; Bone Marrow Transplantation; Chimerism; Electrons; Genetic Dise

1965
HETEROTOPIC LIVER TRANSPLANTATION AFTER LIVER DAMAGE.
    Transactions - American Society for Artificial Internal Organs, 1965, Volume: 11

    Topics: Animals; Azathioprine; Bacillus megaterium; Bile; Carnivora; Dogs; Immunosuppressive Agents; Liver;

1965
Rapamycin successfully treats post-transplant autoimmune hepatitis.
    American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2005, Volume: 5, Issue:5

    Topics: Autoantibodies; Azathioprine; Biopsy; Calcineurin Inhibitors; Child; Child, Preschool; Hepatitis, Au

2005
Incidence, risk factors and clinical course of thiopurine-induced liver injury in patients with inflammatory bowel disease.
    Alimentary pharmacology & therapeutics, 2005, Nov-01, Volume: 22, Issue:9

    Topics: Adolescent; Adult; Aged; Azathioprine; Biomarkers; Chemical and Drug Induced Liver Injury; Female; H

2005
6-Thioguanine-related hepatotoxicity in patients with inflammatory bowel disease: dose or level dependent?
    Journal of hepatology, 2006, Volume: 44, Issue:4

    Topics: Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Drug

2006
[Hepatopathy in kidney transplant patients: incidence, etiology and clinical forms of presentation].
    Medicina clinica, 1984, May-12, Volume: 82, Issue:18

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Cytomegalovirus Inf

1984
Liver grafting.
    Transplantation, 1983, Volume: 35, Issue:2

    Topics: Azathioprine; Cyclosporins; Graft Rejection; Graft Survival; Humans; Liver Diseases; Liver Neoplasms

1983
Azathioprine withdrawal in renal transplant recipients. A long-term follow-up.
    Transplantation, 1984, Volume: 38, Issue:1

    Topics: Adolescent; Adult; Azathioprine; Cerebrovascular Disorders; Female; Graft Survival; Humans; Kidney T

1984
Favourable outcome of hepatic veno-occlusive disease in a renal transplant patient receiving azathioprine, treated by portacaval shunt. Report of a case and review of the literature.
    Digestion, 1984, Volume: 30, Issue:3

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Constriction, Pathologic; Hepatic Veins; Human

1984
Decreased serum aspartate aminotransferase activity in patients receiving corticosteroids and/or azathioprine.
    Nephron, 1984, Volume: 36, Issue:1

    Topics: Aspartate Aminotransferases; Azathioprine; Hepatitis; Humans; Liver Diseases; Prednisone

1984
[Liver injury in kidney transplant patients receiving azathioprine (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1980, Volume: 77, Issue:1

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Azathioprine; Chemical and Drug Induced Liver Inj

1980
Withdrawal of azathioprine after renal transplantation.
    Transplantation proceedings, 1980, Volume: 12, Issue:3

    Topics: Azathioprine; Creatinine; Humans; Immunoglobulin Idiotypes; Kidney Transplantation; Liver Diseases;

1980
Immunologic response to liver cell allografts.
    The American surgeon, 1982, Volume: 48, Issue:1

    Topics: Animals; Azathioprine; Disease Models, Animal; Dogs; Graft Rejection; Liver; Liver Diseases; Liver T

1982
Clinical features and prognosis of severe chronic active liver disease (CALD) after corticosteroid-induced remission.
    Gastroenterology, 1980, Volume: 78, Issue:3

    Topics: Azathioprine; Biopsy; Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Hepatic Encepha

1980
[Can the quality of a modest liver transplantation program compare to international standards? Results in Inselspital Berne].
    Schweizerische medizinische Wochenschrift, 1994, Nov-26, Volume: 124, Issue:47

    Topics: Adult; Aged; Azathioprine; Cyclosporine; Female; Graft Rejection; Hospitals, Community; Humans; Live

1994
[Orthotopic liver transplantation (first clinical experience)].
    Khirurgiia, 1993, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Carcinoma, Hepatocellular; Child; Cyclospo

1993
Combined liver-kidney transplantation: long-term follow-up in 18 patients.
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Adult; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studies; Graft Rejec

1998
[Liver transplantation: experiences and results of a program at the University of Liege].
    Revue medicale de Liege, 1998, Volume: 53, Issue:12

    Topics: Actuarial Analysis; Acute Disease; Adrenal Cortex Hormones; Adult; Azathioprine; Belgium; Chronic Di

1998
[Isoenzyme differentiation of gamma-glutamyltransferase by concanavalin A and Con- A-Sepharose (author's transl)].
    Klinische Wochenschrift, 1976, May-01, Volume: 54, Issue:9

    Topics: Azathioprine; Chemical and Drug Induced Liver Injury; Chemical Precipitation; Chromatography, Affini

1976
[Demonstration of more sialylized fetal enzyme variants of serum gamma-glutamyltransferase in patients with liver diseases and during azathioprine therapy. A new diagnostic parameter].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84

    Topics: Azathioprine; gamma-Glutamyltransferase; Genetic Variation; Humans; Liver; Liver Diseases; Regenerat

1978
[Biochemical and morphological study on hepato-toxicity of azathioprine in rat (author's transl)].
    Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, 1979, Volume: 76, Issue:9

    Topics: Alkaline Phosphatase; Animals; Azathioprine; Chemical and Drug Induced Liver Injury; gamma-Glutamylt

1979
Spectrum of liver disease in renal transplant recipients.
    Gastroenterology, 1975, Volume: 68, Issue:4 Pt 1

    Topics: Acute Disease; Azathioprine; Bilirubin; Chemical and Drug Induced Liver Injury; Cytomegalovirus; Hep

1975
Hepatic dysfunction in recipients of renal allografts.
    Surgery, gynecology & obstetrics, 1975, Volume: 141, Issue:2

    Topics: Alanine Transaminase; Alkaline Phosphatase; Antigens, Viral; Aspartate Aminotransferases; Azathiopri

1975
Jaundice after renal allotransplantation.
    Annals of surgery, 1978, Volume: 188, Issue:6

    Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Azathioprine; Bilirubin; Blood Transfusion

1978
Etiology of liver disease in renal-transplant patients.
    Annals of internal medicine, 1979, Volume: 91, Issue:3

    Topics: Antibodies, Viral; Azathioprine; Cytomegalovirus Infections; Hepatitis B; Hepatitis, Viral, Human; H

1979
Liver transplantation.
    Zeitschrift fur Gastroenterologie, 1978, Volume: 16, Issue:12

    Topics: Adult; Age Factors; Animals; Antilymphocyte Serum; Azathioprine; Biliary Tract; Child; Dogs; Graft R

1978
Hepatic dysfunction in renal transplant recipients: a serious problem.
    Transplantation proceedings, 1979, Volume: 11, Issue:2

    Topics: Azathioprine; Hepatitis; Humans; Kidney Transplantation; Liver Diseases; Postoperative Complications

1979
Chronic active liver disease. Definition, diagnosis, and management.
    The Medical clinics of North America, 1979, Volume: 63, Issue:2

    Topics: Azathioprine; Chronic Disease; Diagnosis, Differential; Hepatitis; Humans; Liver Diseases; Prednison

1979
[Immunosuppressive drugs in the treatment of liver diseases (author's transl)].
    Therapeutische Umschau. Revue therapeutique, 1979, Volume: 36, Issue:5

    Topics: Aspartate Aminotransferases; Azathioprine; Chronic Disease; Hepatitis; Hepatitis, Alcoholic; Humans;

1979
Assessment of the (14C) aminopyrine breath test in liver disease.
    Gut, 1978, Volume: 19, Issue:1

    Topics: Adolescent; Adult; Aged; Aminopyrine; Azathioprine; Breath Tests; Carbon Radioisotopes; Chronic Dise

1978
Serum squalene levels in hepatobiliary diseases.
    Clinica chimica acta; international journal of clinical chemistry, 1978, Aug-15, Volume: 88, Issue:1

    Topics: Acute Disease; Adult; Azathioprine; Biliary Tract Diseases; Cholestasis; Cholesterol; Cholestyramine

1978
Malignancy in chronic liver disease.
    Gastroenterology, 1977, Volume: 73, Issue:1

    Topics: Adult; Azathioprine; Drug Therapy, Combination; Follow-Up Studies; Humans; Liver Diseases; Middle Ag

1977
[Thrombocytopenia in hepatitis-B-antigenemia (author's transl)].
    Medizinische Klinik, 1976, Jun-04, Volume: 71, Issue:23

    Topics: Azathioprine; Blood Cell Count; Blood Platelets; Female; Hepatitis; Hepatitis B Antigens; Humans; Li

1976
Responses to treatment can differentiate chronic active liver disease with cholangitic features from the primary biliary cirrhosis syndrome.
    Gastroenterology, 1976, Volume: 71, Issue:3

    Topics: Adolescent; Adult; Aged; Autoimmune Diseases; Azathioprine; Cholangitis; Chronic Disease; Drug Admin

1976
Serum migration inhibitory activity in patients with posttransplantation hepatic dysfunction.
    Clinical immunology and immunopathology, 1975, Volume: 3, Issue:3

    Topics: Animals; Antilymphocyte Serum; Aspartate Aminotransferases; Azathioprine; Cell Migration Inhibition;

1975
Hepatic veno-occlusive disease in a renal transplant patient receiving azathioprine.
    Gastroenterology, 1975, Volume: 69, Issue:3

    Topics: Azathioprine; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Humans; Kidney Transplan

1975
Influence of azathioprine on hepatic reserve in chronic active liver disease.
    Gut, 1975, Volume: 16, Issue:3

    Topics: Adolescent; Adult; Aged; Aspartate Aminotransferases; Azathioprine; Bilirubin; Chronic Disease; Clin

1975
Letter: Prednisone and azathioprine treatment of liver disease.
    Gastroenterology, 1975, Volume: 68, Issue:5 Pt 1

    Topics: Azathioprine; Chronic Disease; Humans; Liver Diseases; Prednisone

1975
Frontiers in inflammatory bowel disease. The proceedings of a conference sponsored by the McReynolds Foundation. Part II.
    The American journal of digestive diseases, 1975, Volume: 20, Issue:7

    Topics: Adenocarcinoma; Arthritis; Azathioprine; Child; Chronic Disease; Colitis, Ulcerative; Colonic Neopla

1975
Liver disease in renal transplant recipients.
    Transplantation proceedings, 1992, Volume: 24, Issue:5

    Topics: Azathioprine; Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; Granuloma; Hepatitis; Hepa

1992
Five-year results of thoracic duct drainage in living related donor kidney transplantation.
    Transplantation proceedings, 1992, Volume: 24, Issue:4

    Topics: Azathioprine; Creatinine; Cyclosporine; Graft Survival; Humans; Immunosuppression Therapy; Kidney Tr

1992
Renal transplant recipients and chronic liver disease: statistical evaluation of predisposing factors.
    Nephron, 1992, Volume: 61, Issue:3

    Topics: Adult; Azathioprine; Chronic Disease; Cyclosporine; Female; Hepatitis B Surface Antigens; Humans; Ki

1992
Acute adenovirus hepatitis in liver transplant recipients.
    The Journal of pediatrics, 1992, Volume: 120, Issue:1

    Topics: Adenovirus Infections, Human; Adenoviruses, Human; Azathioprine; Biliary Atresia; Child, Preschool;

1992
Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1990, Volume: 49, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Eruptions; D

1990
Chronic liver diseases: current therapeutic options.
    Hospital practice (Office ed.), 1989, Mar-15, Volume: 24, Issue:3

    Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Cholangitis, Sclerosing; Chronic Disease

1989
Role of endothelial cell injury in the spectrum of azathioprine-induced liver disease after renal transplant: light microscopy and ultrastructural observations.
    The American journal of gastroenterology, 1988, Volume: 83, Issue:3

    Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Endothelium; Female; Hepatomegaly; Huma

1988
Combination therapy of cyclosporine and azathioprine in living-related kidney transplant recipients compared with patients converted totally from cyclosporine to azathioprine.
    Transplantation proceedings, 1988, Volume: 20, Issue:3 Suppl 3

    Topics: Azathioprine; Creatinine; Cyclosporins; Dose-Response Relationship, Drug; Drug Administration Schedu

1988
Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment: a cause of chronic liver disease after kidney transplantation.
    Transplantation proceedings, 1987, Volume: 19, Issue:5

    Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Chronic Disease; Female; Humans; Hypert

1987
Azathioprine and hepatic venocclusive disease in renal transplant patients.
    Gastroenterology, 1986, Volume: 90, Issue:2

    Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Hepatic Veins; Humans; Immunosuppressio

1986
Peliosis hepatis in a renal transplant recipient and in a haemodialysis patient.
    The Medical journal of Australia, 1987, Jan-19, Volume: 146, Issue:2

    Topics: Adult; Azathioprine; Biopsy; Humans; Immunosuppression Therapy; Kidney Transplantation; Liver; Liver

1987
Prospective study and long-term follow-up of liver damage in renal transplant recipients.
    Transplantation proceedings, 1987, Volume: 19, Issue:1 Pt 3

    Topics: Adolescent; Adult; Azathioprine; Female; Follow-Up Studies; Hepatitis B Surface Antigens; Humans; Im

1987
Azathioprine hypersensitivity manifesting as acute focal hepatocellular necrosis.
    Journal of the Royal Society of Medicine, 1986, Volume: 79, Issue:3

    Topics: Arthritis, Rheumatoid; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity;

1986
Hepatic sinusoidal dilatation with portal hypertension during azathioprine treatment after kidney transplantation.
    Journal of hepatology, 1985, Volume: 1, Issue:4

    Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Esophagus; Female; Humans; Hypertension

1985
Liver disease in recipients of long-functioning renal allografts.
    Kidney international, 1985, Volume: 28, Issue:5

    Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Azathioprine; Bacterial Infections; Carrie

1985
Immunopathological studies of orthotopic human liver allografts.
    Lancet (London, England), 1972, Feb-05, Volume: 1, Issue:7745

    Topics: Adolescent; Adult; Autopsy; Azathioprine; Biliary Tract Diseases; Biopsy; Child; Child, Preschool; C

1972
Serum immunosuppressive activity due to azathioprine and its relation to hepatic function after liver transplantation.
    Lancet (London, England), 1970, Jun-06, Volume: 1, Issue:7658

    Topics: Adult; Autoimmune Diseases; Azathioprine; Biliary Tract; Child, Preschool; Cholestasis; Humans; Immu

1970
[Penicillamine therapy of chronic liver diseases].
    MMW, Munchener medizinische Wochenschrift, 1974, Feb-01, Volume: 116, Issue:5

    Topics: Azathioprine; Chronic Disease; Drug Hypersensitivity; Female; Glucocorticoids; Hepatitis; Humans; Li

1974
IgM turnover in chronic liver disease.
    Scandinavian journal of immunology, 1972, Volume: 1, Issue:2

    Topics: Azathioprine; Blood Volume; Chromatography, Gel; Creatinine; Female; Hepatitis; Hepatolenticular Deg

1972
Clinical and pathologic observations after orthotopic transplantation of the human liver.
    Surgery, gynecology & obstetrics, 1969, Volume: 128, Issue:2

    Topics: Adolescent; Adult; Alkaline Phosphatase; Azathioprine; Bilirubin; Blood Proteins; Carcinoma, Hepatoc

1969
Orthotopic liver transplantation in man.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Adrenal Gland Diseases; Adult; Anticoagulants; Antilymphocyte Serum; Azathioprine; Blood Coagulation

1969
Total haemolytic complement after liver transplantation and in liver disease.
    Transplantation, 1972, Volume: 14, Issue:1

    Topics: Acute Disease; Adult; Aspartate Aminotransferases; Azathioprine; Bilirubin; Carcinoma, Hepatocellula

1972
[Azathioprine and hepatic functional structures (clinical and experimental studies)].
    Revue roumaine de physiologie, 1973, Volume: 10, Issue:4

    Topics: Animals; Azathioprine; Blood Proteins; Hepatitis; Humans; Lipoproteins; Liver; Liver Cirrhosis; Live

1973
Renal transplantation in children.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1972, Volume: 9

    Topics: Adolescent; Adult; Azathioprine; Bone Development; Bone Diseases; Candidiasis; Child; Child, Prescho

1972
Clinical implications of monoclonal gammopathy in chronic liver disease.
    The American journal of digestive diseases, 1974, Volume: 19, Issue:3

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Azathioprine; Blood Protein Disorders; Blood P

1974
Liver disease in transplanted patients.
    Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association, 1973, Volume: 10, Issue:0

    Topics: Azathioprine; Clinical Enzyme Tests; Cytomegalovirus; Cytomegalovirus Infections; Female; Graft Reje

1973
Clinical use of corticosteroid and immunosuppressive drugs in liver disease.
    Drugs, 1974, Volume: 8, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Azathioprine; Biliary Tract Diseases; Chemical and D

1974
[Liver tolerance to azathioprine in immunosuppressive therapy of chronic active liver diseases].
    Ceskoslovenska gastroenterologie a vyziva, 1974, Volume: 28, Issue:1

    Topics: Animals; Azathioprine; Chronic Disease; Drug Tolerance; Humans; Liver; Liver Diseases; Rats

1974
[Rehabilitation of patients with chronic liver diseases. Monitoring and therapy in the practive].
    Fortschritte der Medizin, 1974, Dec-05, Volume: 92, Issue:34

    Topics: Alcoholism; Azathioprine; Chronic Disease; Cortisone; Family Practice; Fatty Liver; Germany, West; H

1974
Liver disease in childhood: principles of management.
    Postgraduate medical journal, 1974, Volume: 50, Issue:584

    Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Female; Hepatitis; Hepatitis B Antigens; H

1974
The influence of histocompatibility matching according to lymphocyte types on orthotopic liver transplantation in dogs.
    Surgery, 1972, Volume: 71, Issue:6

    Topics: Animals; Azathioprine; Dogs; Erythrocytes; Histocompatibility Testing; Leukocytes; Liver; Liver Dise

1972
Irreversible liver damage after azathioprine.
    JAMA, 1972, Nov-06, Volume: 222, Issue:6

    Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Autopsy; Azathioprine; Chemical and Drug I

1972
Serum immunosuppressive activity of azathioprine in normal subjects and patients with liver diseases.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:3

    Topics: Animals; Azathioprine; Graft Rejection; Hepatitis A; Humans; Immune Adherence Reaction; Kinetics; Li

1972
Mitochondrial antibody in primary biliary cirrhosis and other diseases.
    Annals of internal medicine, 1972, Volume: 77, Issue:4

    Topics: Antibodies; Azathioprine; Biliary Tract Diseases; Biopsy; Chemical and Drug Induced Liver Injury; Ch

1972
Ultrastructure of peliosis hepatis in a percutaneous biopsy.
    Pathologia Europaea, 1972, Volume: 7, Issue:3

    Topics: Azathioprine; Biopsy, Needle; Chemical and Drug Induced Liver Injury; Endoplasmic Reticulum; Heart T

1972
Liver disease in kidney transplant patients receiving azathioprine.
    Archives of internal medicine, 1973, Volume: 132, Issue:1

    Topics: Adolescent; Adult; Alkaline Phosphatase; Amylases; Aspartate Aminotransferases; Azathioprine; Biliru

1973
Corticosteroids in liver disease: studies on the biological conversion of prednisone to prednisolone and plasma protein binding.
    Gut, 1972, Volume: 13, Issue:9

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Aspartate Aminotransferases; Azathioprine; Bilirubin;

1972
Immunosuppressive activity in patients with active chronic hepatitis and primary biliary cirrhosis treated with azathioprine.
    Gut, 1972, Volume: 13, Issue:11

    Topics: Adolescent; Adult; Animals; Azathioprine; Chronic Disease; Erythrocytes; Female; Hepatitis; Humans;

1972
Chronic active liver disease: classification and treatment.
    Postgraduate medicine, 1973, Volume: 53, Issue:1

    Topics: Aspartate Aminotransferases; Autoimmune Diseases; Azathioprine; Chronic Disease; Diagnosis, Differen

1973
Some aspects of Crohn's disease.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1973, Aug-11, Volume: 47, Issue:31

    Topics: Adult; Aged; Anus Diseases; Azathioprine; Colitis; Colitis, Ulcerative; Colonic Diseases; Crohn Dise

1973
[Long-term therapy of liver diseases].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Jun-01, Volume: 28, Issue:11

    Topics: Adolescent; Adult; Azathioprine; Cholestasis; Cholestyramine Resin; Chronic Disease; Cyclophosphamid

1973
[Immunoglobulins and histological findings in chronic liver diseases treated with immunosuppressive agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1973, Jun-01, Volume: 28, Issue:11

    Topics: Adult; Aged; Azathioprine; Chronic Disease; Hepatitis; Humans; Immunoglobulin A; Immunoglobulin G; I

1973
[Chronic-aggressive hepatitis].
    Zeitschrift fur Allgemeinmedizin, 1973, Nov-20, Volume: 49, Issue:32

    Topics: Azathioprine; Carrier State; Chronic Disease; Diagnosis, Differential; Hepatitis A; Humans; Liver Di

1973
[Azathioprine pharmacokinetics in animal experiment and in patients with chronic liver diseases].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1973, Volume: 79

    Topics: Animals; Azathioprine; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Rats; Su

1973
[Indications, method and effectiveness of immunosuppressive treatment in chronic active hepatopathies. I. Changes in the general dynamics of the disease. II. Slowing-down of the chronicization process].
    Medicina interna, 1974, Volume: 26, Issue:4

    Topics: Adult; Azathioprine; Chronic Disease; Female; Hepatitis; Humans; Immunosuppressive Agents; Liver Cir

1974
[Indications, method and effectiveness of immunosuppressive treatment in chronic active hepatopathies. 3. Evolution of the immunologic picture. IV. Improvement of the functional parameters].
    Medicina interna, 1974, Volume: 26, Issue:4

    Topics: Azathioprine; Blood Proteins; Chronic Disease; Drug Therapy, Combination; Humans; Immunoglobulins; I

1974
Evaluation of cellular immunity in chronic liver diseases during immunosuppressive treatment.
    Bollettino dell'Istituto sieroterapico milanese, 1974, Volume: 53, Issue:1

    Topics: Antilymphocyte Serum; Azathioprine; Chronic Disease; Cortisone; Hepatitis; Humans; Immune Adherence

1974
Hepatic sepsis after liver transplantation in dogs and pigs.
    Archives of pathology, 1969, Volume: 88, Issue:2

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Cholangitis; Dogs; Immunosuppressive Agents; Infections

1969
Liver transplantation.
    Studium generale; Zeitschrift fur die Einheit der Wissenschaften im Zusammenhang ihrer Begriffsbildungen und Forschungsmethoden, 1970, Volume: 23, Issue:4

    Topics: Antilymphocyte Serum; Atrophy; Azathioprine; Biliary Tract; Congenital Abnormalities; Histocompatibi

1970
Coproporphyrinuria and heart transplantation: its significance.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1970, Sep-12, Volume: 44, Issue:36

    Topics: Age Factors; Anemia, Hemolytic; Azathioprine; Chemical and Drug Induced Liver Injury; Electrocardiog

1970
Hepatitis and liver damage among patients and staff in a transplantation unit.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Adult; Azathioprine; Carrier State; Cross Infection; Female; Glucocorticoids; Graft Rejection; Hepat

1969
[Studies on the metabolism of azathioprine].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1970, Jul-27, Volume: 271, Issue:4

    Topics: Animals; Antigen-Antibody Reactions; Azathioprine; Bone Marrow Diseases; Erythrocytes; Humans; In Vi

1970
Immunosuppression, liver injury, and hepatitis in renal, hepatic, and cardiac homograft recipients: with particular reference to the Australia antigen.
    Annals of surgery, 1971, Volume: 174, Issue:4

    Topics: Adult; Antibodies, Anti-Idiotypic; Aspartate Aminotransferases; Azathioprine; Bilirubin; Blood Prote

1971
Cell-mediated immune responses in chronic liver diseases.
    British medical journal, 1972, Feb-26, Volume: 1, Issue:5799

    Topics: Acidosis, Renal Tubular; Antigens; Autoimmune Diseases; Azathioprine; Cell Migration Inhibition; Chr

1972
Significance of azathioprine metabolites.
    Proceedings of the Royal Society of Medicine, 1972, Volume: 65, Issue:3

    Topics: Azathioprine; Binding Sites, Antibody; Carbon Isotopes; Chromatography, Ion Exchange; Humans; Imidaz

1972
Acute massive hepatic necrosis with fatal liver failure.
    The American journal of digestive diseases, 1971, Volume: 16, Issue:9

    Topics: Acute Disease; Adolescent; Adult; Aged; Anticonvulsants; Antitubercular Agents; Azathioprine; Blood

1971
[Immunological implications in hepatic physiopathology].
    Revue roumaine de physiologie, 1971, Volume: 8, Issue:4

    Topics: Azathioprine; Hepatitis; Humans; Immunosuppressive Agents; Lipoproteins; Liver Cirrhosis; Liver Dise

1971
[Immunosuppressive agents in the treatment of chronic liver diseases].
    Casopis lekaru ceskych, 1969, Volume: 108, Issue:46

    Topics: Azathioprine; Bilirubin; Chronic Disease; Enzymes; Female; Humans; Liver Diseases; Male; Middle Aged

1969
[Therapy with immunosuppressive agents in hepatology].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1969, Jun-15, Volume: 24, Issue:12

    Topics: Azathioprine; Colitis; Headache; Hepatitis; Humans; Leukocytes; Liver Cirrhosis; Liver Diseases; Pai

1969
Azathioprine (Imuran) in treatment of hepatic failure.
    Pediatrics, 1970, Volume: 46, Issue:1

    Topics: Azathioprine; Child; Hepatic Encephalopathy; Hepatitis; Humans; Liver Diseases

1970
[Lupoid hepatitis in elderly women treated with imuran and 6-mercaptopurine].
    Terapevticheskii arkhiv, 1970, Volume: 42, Issue:1

    Topics: Azathioprine; Female; Humans; Liver Cirrhosis; Liver Diseases; Lupus Erythematosus, Systemic; Menopa

1970
[Thrombocyte survival time in thrombocytopenias].
    Medizinische Klinik, 1970, Mar-06, Volume: 65, Issue:10

    Topics: Azathioprine; Blood Platelets; Chromium Isotopes; Diagnosis, Differential; Female; Humans; Hypersple

1970
Chronic toxicity of azathioprine and the effect of this immunosuppressant on liver tumor induction by the carcinogen N-hydroxy-N-2-fluorenylacetamide.
    Toxicology and applied pharmacology, 1970, Volume: 17, Issue:2

    Topics: Amides; Animals; Animals, Laboratory; Azathioprine; Body Weight; Carcinogens; Diet; Female; Liver; L

1970
[Immunosuppressive effect of cytostatics in the clinic].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1970, Jul-21, Volume: 59, Issue:29

    Topics: Azathioprine; Colitis, Ulcerative; Collagen Diseases; Granulomatosis with Polyangiitis; Hematologic

1970
[Treatment of chronic nonalcoholic hepatopathy with azathioprine-prednisone: preliminary report].
    Acta gastro-enterologica Belgica, 1968, Volume: 31, Issue:11

    Topics: Azathioprine; Drug Synergism; Humans; Liver Diseases; Prednisone

1968