azathioprine has been researched along with Limb-Girdle Muscular Dystrophies in 2 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations." | 7.75 | Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009) |
| "An 11-year-old girl with a calpain-3 gene (CAPN-3) mutation and eosinophilic myositis on muscle biopsy had high serum CK levels and eosinophil counts which showed spontaneous fluctuations." | 3.75 | Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease? ( Dincer, P; Gundesli, H; Oflazer, PS; Sabuncu, T; Zorludemir, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Svahn, J | 1 |
| Streichenberger, N | 1 |
| Benveniste, O | 1 |
| Menassa, R | 1 |
| Michel, L | 1 |
| Fayolle, H | 1 |
| Petiot, P | 1 |
| Oflazer, PS | 1 |
| Gundesli, H | 1 |
| Zorludemir, S | 1 |
| Sabuncu, T | 1 |
| Dincer, P | 1 |
2 other studies available for azathioprine and Limb-Girdle Muscular Dystrophies
| Article | Year |
|---|---|
Significant response to immune therapies in a case of subacute necrotizing myopathy and FKRP mutations.
Topics: Adrenal Cortex Hormones; Azathioprine; Creatine Kinase; Diagnosis, Differential; Female; Humans; Imm | 2015 |
Eosinophilic myositis in calpainopathy: could immunosuppression of the eosinophilic myositis alter the early natural course of the dystrophic disease?
Topics: Azathioprine; Calpain; Child; Creatine Kinase; Disease Progression; Dose-Response Relationship, Drug | 2009 |