azathioprine has been researched along with Lichen Ruber Planus in 10 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine has been shown to be effective steroid sparing treatment for generalized lichen planus." | 5.29 | Erosive and generalized lichen planus responsive to azathioprine. ( English, JS; Lear, JT, 1996) |
| "Azathioprine has been shown to be effective steroid sparing treatment for generalized lichen planus." | 1.29 | Erosive and generalized lichen planus responsive to azathioprine. ( English, JS; Lear, JT, 1996) |
| "Oral lichen planus was found mainly in women and most commonly on the buccal mucosa." | 1.28 | A prospective study of findings and management in 214 patients with oral lichen planus. ( Giannotti, K; Gorsky, M; Lozada-Nur, F; Silverman, S, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Massa, AF | 1 |
| Campos, MA | 1 |
| Baptista, A | 1 |
| Costa, C | 1 |
| Lima, O | 1 |
| Osório Ferreira, E | 1 |
| Sakuma-Oyama, Y | 1 |
| Powell, AM | 1 |
| Albert, S | 1 |
| Oyama, N | 1 |
| Bhogal, BS | 2 |
| Black, MM | 2 |
| Bailin, PL | 1 |
| Matkaluk, RM | 1 |
| Paige, DG | 1 |
| Harper, JI | 1 |
| Lear, JT | 1 |
| English, JS | 1 |
| Krunic, AL | 1 |
| Kokai, D | 1 |
| Bacetic, B | 1 |
| Kesic, V | 1 |
| Nikolic, MM | 1 |
| Petkovic, S | 1 |
| Clark, RE | 1 |
| Verma, KK | 1 |
| Sirka, CS | 1 |
| Khaitan, BK | 1 |
| Klein, LR | 1 |
| Callen, JP | 1 |
| Silverman, S | 1 |
| Gorsky, M | 1 |
| Lozada-Nur, F | 1 |
| Giannotti, K | 1 |
| Crompton, DO | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| An Open-Label Pilot Study to Evaluate the Safety and Efficacy of Apremilast (CC-10004) in the Treatment of Moderate to Severe Lichen Planus[NCT01041625] | Phase 2 | 10 participants (Anticipated) | Interventional | 2010-02-28 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Lichen Ruber Planus
| Article | Year |
|---|---|
Cutaneous reactions to rheumatological drugs.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cushing Syndrome; Cy | 1982 |
9 other studies available for azathioprine and Lichen Ruber Planus
| Article | Year |
|---|---|
Paediatric anogenital Crohn's disease 11 years after Lichen planus - same background for two different entities?
Topics: Anal Canal; Azathioprine; Child; Ciprofloxacin; Crohn Disease; Drug Therapy, Combination; Female; Ge | 2016 |
Lichen planus pemphigoides evolving into pemphigoid nodularis.
Topics: Autoantigens; Azathioprine; Carrier Proteins; Collagen Type XVII; Cytoskeletal Proteins; Dystonin; E | 2003 |
Lichen planus pemphigoides in a child--immunopathological findings.
Topics: Azathioprine; Child; Drug Combinations; Humans; Lichen Planus; Male; Prednisolone; Skin | 1993 |
Erosive and generalized lichen planus responsive to azathioprine.
Topics: Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Lichen Planus; Middle Aged; Treatment | 1996 |
Retroperitoneal round-cell liposarcoma associated with paraneoplastic pemphigus presenting as lichen planus pemphigoides-like eruption.
Topics: Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Azathioprine; Diagnosis, Differential; Fe | 1997 |
Generalized severe lichen planus treated with azathioprine.
Topics: Administration, Oral; Adult; Azathioprine; Female; Follow-Up Studies; Humans; Immunosuppressive Agen | 1999 |
Azathioprine: effective steroid-sparing therapy for generalized lichen planus.
Topics: Azathioprine; Biopsy; Chronic Disease; Humans; Lichen Planus; Male; Middle Aged; Remission Induction | 1992 |
A prospective study of findings and management in 214 patients with oral lichen planus.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Azathioprine; Carboxymethylcellulose Sodium; F | 1991 |
Immuno-suppressive drug treatment of keratitis sicca, including an example of lichen planus of the conjunctiva.
Topics: Aged; Autoimmune Diseases; Azathioprine; Conjunctivitis; Female; Humans; Keratoconjunctivitis; Liche | 1968 |