azathioprine has been researched along with Leukodystrophy, Metachromatic in 1 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Leukodystrophy, Metachromatic: An autosomal recessive metabolic disease caused by a deficiency of CEREBROSIDE-SULFATASE leading to intralysosomal accumulation of cerebroside sulfate (SULFOGLYCOSPHINGOLIPIDS) in the nervous system and other organs. Pathological features include diffuse demyelination, and metachromatically-staining granules in many cell types such as the GLIAL CELLS. There are several allelic and nonallelic forms with a variety of neurological symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 4-year-old child with metachromatic leukodystrophy was initially diagnosed with chronic immune demyelinating polyneuropathy and treated with immunosuppressive therapy." | 1.29 | Neuropathy of metachromatic leukodystrophy: improvement with immunomodulation. ( Carroll, SL; Lopate, G; Nevo, Y; Pestronk, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nevo, Y | 1 |
| Pestronk, A | 1 |
| Lopate, G | 1 |
| Carroll, SL | 1 |
1 other study available for azathioprine and Leukodystrophy, Metachromatic
| Article | Year |
|---|---|
Neuropathy of metachromatic leukodystrophy: improvement with immunomodulation.
Topics: Azathioprine; Child, Preschool; Cyclosporine; Female; Humans; Immunization, Passive; Immunosuppressi | 1996 |