azathioprine has been researched along with Leukemia P388 in 1 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Leukemia P388: An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In 5 transplantable murine tumor models, including sc Sa180, sc Ca755, ip LL and ip leukemias; L1210 and P388 both drugs were found to be antitumor active in all the experiments carried out regardless of dosing regimen or the route of administration." | 1.28 | Experimental antitumor activity of new azathioprine analogues. ( Bałoniak, S; Gutsche, W; Hładoń, B; Sikorska, H, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hładoń, B | 1 |
| Gutsche, W | 1 |
| Bałoniak, S | 1 |
| Sikorska, H | 1 |
1 other study available for azathioprine and Leukemia P388
| Article | Year |
|---|---|
Experimental antitumor activity of new azathioprine analogues.
Topics: Animals; Antineoplastic Agents; Azathioprine; Cell Survival; Culture Techniques; Humans; KB Cells; L | 1989 |