azathioprine has been researched along with Leukemia, Myeloid in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Leukemia, Myeloid: Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A woman with relapsing-remitting multiple sclerosis (MS) was treated with oral azathioprine (AZA) for 4 years and subsequently switched to interferon-beta1a." | 7.73 | Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis. ( Al-Ali, HK; Niederwieser, D; Niklas, A; Schwarz, J; Strauss, A; Then Bergh, F; von Ahsen, N; Wagner, A, 2006) |
| "A 52-year-old man developed therapy-related acute myeloid leukemia (AML) following prolonged immunosuppression with azathioprine for polymyositis." | 7.69 | Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. ( Adams, P; Dabich, L; Krishnan, K; Sheldon, S; Silveira, S, 1994) |
| "A 66-year-old female with dermatomyositis (DM) who had received immunosuppressive therapy with azathioprine developed acute myeloid leukaemia (AML)." | 4.80 | Azathioprine-associated acute myeloid leukaemia with trilineage dysplasia and complex karyotype: a case report and review of the literature. ( Abdalla, SH; Arnold, JA; Ranson, SA, 1999) |
| "A woman with relapsing-remitting multiple sclerosis (MS) was treated with oral azathioprine (AZA) for 4 years and subsequently switched to interferon-beta1a." | 3.73 | Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis. ( Al-Ali, HK; Niederwieser, D; Niklas, A; Schwarz, J; Strauss, A; Then Bergh, F; von Ahsen, N; Wagner, A, 2006) |
| "A 52-year-old man developed therapy-related acute myeloid leukemia (AML) following prolonged immunosuppression with azathioprine for polymyositis." | 3.69 | Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. ( Adams, P; Dabich, L; Krishnan, K; Sheldon, S; Silveira, S, 1994) |
| " The patient presented is a 22-year-old white male who, following two renal transplants and prolonged immunosuppressive therapy with azathioprine and methylprednisolone, developed chronic granulocytic leukemia." | 3.66 | Chronic granulocytic leukemia following successful renal transplantation. ( Adler, KR; Lempert, N; Scharfman, WB, 1978) |
| "Chronic granulocytic leukemia (CGL) developed in a 31-year-old man after he underwent a third renal transplant." | 1.27 | Chronic granulocytic leukemia after renal transplantation. ( Didlake, R; Files, JC; Kirchner, KA; Krueger, RP; Raju, S, 1983) |
| "Chronic granulocytic leukemia developed four years after renal transplantation in a patient, who had been treated with immunosuppressive agents since then." | 1.26 | Chronic granulocytic leukemia in a renal transplant recipient. ( Hagenouw-Taal, JC; Lameijer, LD; Mooy, JM; van Turnhout, JM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (65.00) | 18.7374 |
| 1990's | 5 (25.00) | 18.2507 |
| 2000's | 2 (10.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Offman, J | 1 |
| Opelz, G | 1 |
| Doehler, B | 1 |
| Cummins, D | 1 |
| Halil, O | 1 |
| Banner, NR | 1 |
| Burke, MM | 1 |
| Sullivan, D | 1 |
| Macpherson, P | 1 |
| Karran, P | 1 |
| Then Bergh, F | 1 |
| Niklas, A | 1 |
| Strauss, A | 1 |
| von Ahsen, N | 1 |
| Niederwieser, D | 1 |
| Schwarz, J | 1 |
| Wagner, A | 1 |
| Al-Ali, HK | 1 |
| Kirchner, KA | 1 |
| Files, JC | 1 |
| Didlake, R | 1 |
| Raju, S | 1 |
| Krueger, RP | 1 |
| Vismans, JJ | 1 |
| Briët, E | 1 |
| Meijer, K | 1 |
| den Ottolander, GJ | 1 |
| Krishnan, K | 1 |
| Adams, P | 1 |
| Silveira, S | 1 |
| Sheldon, S | 1 |
| Dabich, L | 1 |
| Adams, GB | 1 |
| Lipton, JH | 1 |
| Jamal, N | 1 |
| Messner, HA | 1 |
| Subar, M | 1 |
| Gucalp, R | 1 |
| Benstein, J | 1 |
| Williams, G | 1 |
| Wiernik, PH | 1 |
| Kwong, YL | 1 |
| Au, WY | 1 |
| Liang, RH | 1 |
| Arnold, JA | 1 |
| Ranson, SA | 1 |
| Abdalla, SH | 1 |
| Mey, U | 1 |
| Franke, A | 1 |
| Fuchs, R | 1 |
| Mooy, JM | 1 |
| Hagenouw-Taal, JC | 1 |
| Lameijer, LD | 1 |
| van Turnhout, JM | 1 |
| Adler, KR | 1 |
| Lempert, N | 1 |
| Scharfman, WB | 1 |
| Stein, AM | 1 |
| Anthone, R | 1 |
| Anthone, S | 1 |
| Marinello, MJ | 1 |
| Elwood, CM | 1 |
| Bannerman, RM | 1 |
| Mocelin, AJ | 1 |
| Hager, ET | 1 |
| Carpenter, CB | 1 |
| Merrill, JP | 1 |
| Battin, J | 1 |
| Hehunstre, JP | 1 |
| Bui, NB | 1 |
| Auzerie, J | 1 |
| Colle, M | 1 |
| Patterson, R | 1 |
| Irons, JS | 1 |
| Kelly, JF | 1 |
| Mattson, JR | 1 |
| O, SH | 1 |
| Cobau, CD | 1 |
| Sheon, RP | 1 |
| Kirsner, AB | 1 |
| Hitchings, GH | 1 |
| Stacher, A | 1 |
| Böttcher, D | 1 |
| Maas, D | 1 |
| Wendt, F | 1 |
| Schubothe, H | 1 |
2 reviews available for azathioprine and Leukemia, Myeloid
| Article | Year |
|---|---|
Azathioprine-associated acute myeloid leukaemia with trilineage dysplasia and complex karyotype: a case report and review of the literature.
Topics: Acute Disease; Aged; Azathioprine; Dermatomyositis; Female; Humans; Immunosuppressive Agents; Leukem | 1999 |
Chemotherapy and comparative biochemistry: G. H. A. Clowes memorial lecture.
Topics: Allopurinol; Animals; Antimetabolites; Azathioprine; Binding Sites; Drug Therapy; Enzyme Inhibitors; | 1969 |
18 other studies available for azathioprine and Leukemia, Myeloid
| Article | Year |
|---|---|
Defective DNA mismatch repair in acute myeloid leukemia/myelodysplastic syndrome after organ transplantation.
Topics: Acute Disease; Azathioprine; Base Pair Mismatch; Bone Marrow; DNA Repair; Follow-Up Studies; Heart T | 2004 |
Rapid progression of Myelodysplastic syndrome to acute myeloid leukemia on sequential azathioprine, IFN-beta and copolymer-1 in a patient with multiple sclerosis.
Topics: Acute Disease; Azathioprine; Disease Progression; Fatal Outcome; Female; Glatiramer Acetate; Humans; | 2006 |
Chronic granulocytic leukemia after renal transplantation.
Topics: Adult; Allopurinol; Azathioprine; Humans; Hydroxyurea; Kidney Transplantation; Leukemia, Myeloid; Ma | 1983 |
Azathioprine and subacute myelomonocytic leukemia.
Topics: Adult; Azathioprine; Bone Marrow; Female; Humans; Leukemia, Myeloid; Lupus Erythematosus, Systemic | 1980 |
Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis.
Topics: Acute Disease; Azathioprine; Chromosome Deletion; Chromosomes, Human, Pair 5; Chromosomes, Human, Pa | 1994 |
Allogeneic bone marrow transplantation from a related donor undergoing long-term immunosuppressive and cytotoxic therapy.
Topics: Antineoplastic Agents; Azathioprine; Bone Marrow; Bone Marrow Cells; Bone Marrow Transplantation; Cy | 1994 |
Acute leukaemia following renal transplantation.
Topics: Acute Disease; Adult; Alkylating Agents; Azathioprine; Cyclophosphamide; Female; Humans; Immunosuppr | 1996 |
Acute myeloid leukemia after azathioprine treatment for autoimmune diseases: association with -7/7q-.
Topics: Acute Disease; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chromosomes, Human, Pair 7; Female; | 1998 |
[Acute mature myelocytic leukemia as a form of the myeloproliferative syndrome].
Topics: Acute Disease; Adult; Azathioprine; Bone Marrow Examination; Fetal Hemoglobin; Hematopoietic Stem Ce | 1979 |
Chronic granulocytic leukemia in a renal transplant recipient.
Topics: Azathioprine; Cadaver; Humans; Kidney Transplantation; Leukemia, Myeloid; Male; Middle Aged; Oncogen | 1978 |
Chronic granulocytic leukemia following successful renal transplantation.
Topics: Adult; Azathioprine; Cadaver; Chromosomes, Human, 21-22 and Y; Chromosomes, Human, 6-12 and X; Human | 1978 |
Chronic myelocytic leukemia in a young renal allografted patient.
Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Cytogenetics; Humans; Kidney Transplantation; Leu | 1978 |
[Medullar aplasia due to concomitant use of azathioprine and allopurinol in kidney transplantation. Probable beneficial effects of infusion of leukemic cells].
Topics: Adult; Allopurinol; Anemia, Aplastic; Azathioprine; Blood Transfusion; Drug Interactions; Humans; Ki | 1976 |
[Chronic myeloid leukemia after immunosuppressive treatment for chronic nephropathy].
Topics: Adolescent; Azathioprine; Glomerulonephritis; Humans; Leukemia, Myeloid; Male | 1976 |
Pulmonary infiltrates with eosinophilia.
Topics: Aspergillosis; Asthma; Azathioprine; Eosinophilia; Eosinophils; Humans; Leukemia, Myeloid; Lung Dise | 1974 |
Immunosuppressive drugs and acute leukemia.
Topics: Aged; Arthritis, Rheumatoid; Azathioprine; Cyclophosphamide; Dose-Response Relationship, Drug; Human | 1973 |
[Progress in the therapy of leukoses].
Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; | 1970 |
[Anemia caused by erythroblastopenia in adult age].
Topics: Aged; Analgesics; Anemia, Aplastic; Azathioprine; Blood Transfusion; Female; Heart Failure; Hepatiti | 1970 |