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azathioprine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

azathioprine has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 7 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Research Excerpts

ExcerptRelevanceReference
"Detection of the chronic myelogenous leukemia (CML)-related marker, the bcr/abl m-RNA transcript, in blood or bone marrow of patients with CML in hematologic remission after allogeneic bone marrow transplantation (allo-BMT) may be associated with the presence of minimal residual disease but does not uniformly predict hematologic relapse."1.29Case report of spontaneous remission of cytogenetic relapse of chronic myelogenous leukemia suggestive of progression to blast crisis after allogeneic bone marrow transplantation. ( Agaliotis, DP; Elfenbein, GJ; Moscinski, LC; Papenhausen, PR, 1995)
"A patient is reported who developed chronic myelogenous leukemia (CML) six years after renal transplantation, which was followed by immunosuppressive with azathioprine, and the published data on such an association are reviewed."1.29[Chronic myeloid leukemia after renal transplantation: report of a new case and review of the bibliography]. ( Cervantes, F; Esteve, J; Marín, P; Montserrat, E; Rozman, C; Sanz, L; Vilardell, J, 1996)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's3 (42.86)29.6817
2010's0 (0.00)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Zaimi, Y1
Bouksir, C1
Ayadi, S1
Ayari, M1
Ksontini, FL1
Pelloso, LA1
Campos, MG1
Nascimento, M1
Silva, MR1
Pestana, JO1
Chauffaille, Mde L1
Habib, S1
Nalesnik, MA1
Ahmad, J1
BuchBarker, D1
Shakil, AO1
Segawa, F1
Shimizu, Y1
Saito, E1
Kinoshita, M1
Agaliotis, DP1
Papenhausen, PR1
Moscinski, LC1
Elfenbein, GJ1
Sanz, L1
Cervantes, F1
Esteve, J1
Vilardell, J1
Marín, P1
Rozman, C1
Montserrat, E1
Mignozzi, M1
Picca, S1

Reviews

1 review available for azathioprine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
Imputability of Azathioprine in the Occurrence of Chronic Myeloid Leukemia in Crohn's Disease: An Exceptional Case Report.
    Current drug safety, 2023, Volume: 18, Issue:4

    Topics: Azathioprine; Chronic Disease; Crohn Disease; Female; Humans; Immunosuppressive Agents; Leukemia, My

2023

Other Studies

6 other studies available for azathioprine and Leukemia, Myelogenous, Chronic, BCR-ABL Positive

ArticleYear
Chronic myeloid leukemia following kidney transplantation.
    Leukemia research, 2005, Volume: 29, Issue:3

    Topics: Adult; Azathioprine; Humans; Immunocompromised Host; Immunosuppressive Agents; Kidney Transplantatio

2005
Alloimmune hepatitis following peripheral stem cell transplantation.
    Bone marrow transplantation, 2007, Volume: 39, Issue:9

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Busulfan; Cyclophosphamide; Female; Graft vs Host Dis

2007
Behçet's disease induced by interferon therapy for chronic myelogenous leukemia.
    The Journal of rheumatology, 1995, Volume: 22, Issue:6

    Topics: Azathioprine; Behcet Syndrome; Female; Humans; Interferon-alpha; Leukemia, Myelogenous, Chronic, BCR

1995
Case report of spontaneous remission of cytogenetic relapse of chronic myelogenous leukemia suggestive of progression to blast crisis after allogeneic bone marrow transplantation.
    Annals of hematology, 1995, Volume: 70, Issue:1

    Topics: Adult; Azathioprine; Blast Crisis; Bone Marrow Transplantation; Female; Graft vs Host Disease; Human

1995
[Chronic myeloid leukemia after renal transplantation: report of a new case and review of the bibliography].
    Sangre, 1996, Volume: 41, Issue:5

    Topics: Adult; Azathioprine; Cyclosporine; Female; Humans; Hydroxyurea; Immunosuppressive Agents; Incidence;

1996
Chronic myelogenous leukemia following kidney transplantation in a pediatric patient.
    Pediatric nephrology (Berlin, Germany), 2001, Volume: 16, Issue:11

    Topics: Adolescent; Antineoplastic Agents; Azathioprine; Human Growth Hormone; Humans; Hydroxyurea; Immunosu

2001