azathioprine has been researched along with Leukemia, Lymphoid in 22 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Leukemia, Lymphoid: Leukemia associated with HYPERPLASIA of the lymphoid tissues and increased numbers of circulating malignant LYMPHOCYTES and lymphoblasts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Four cases of acute myelogenous leukemia and six cases of chronic myelogenous leukemia after treatment with azathioprine and prednisone for renal allotransplantation have been described in the literature." | 3.66 | [Acute leukemia after kidney allotransplantation (author's transl)]. ( Binswanger, U; Briner, J; Fehr, J; Frei, D; Largiadèr, F; Sauter, C, 1980) |
| "B-, T- and O-lymphocytes detected as EAC-, E- and non-rosette forming lymphocytes were investigated in venous blood in 49 patients with connective tissue diseases, psoriasis and chronic lymphogenous leukaemia (CLL) during treatment with either prednisone alone, prednisone and cytostatic agents or cytostatic agents alone." | 3.65 | Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases. ( Jonsson, V, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (95.45) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MATHE, G | 2 |
| AMIEL, JL | 2 |
| SCHWARZENBERG, L | 2 |
| CATTAN, A | 2 |
| SCHNEIDER, M | 2 |
| DEVRIES, MJ | 1 |
| TUBIANA, M | 1 |
| LALANNE, C | 1 |
| BINET, JL | 1 |
| PAPIERNIK, M | 1 |
| SEMAN, G | 1 |
| MATSUKURA, M | 1 |
| MERY, AM | 1 |
| SCHWARZMANN, V | 1 |
| FLAISLER, A | 1 |
| Lennard, L | 2 |
| Maddocks, JL | 1 |
| Frei, D | 1 |
| Binswanger, U | 1 |
| Fehr, J | 1 |
| Briner, J | 1 |
| Sauter, C | 1 |
| Largiadèr, F | 1 |
| Fisch, P | 1 |
| Handgretinger, R | 1 |
| Schaefer, HE | 1 |
| Pirofsky, B | 1 |
| Jonsson, V | 1 |
| Vernant, JP | 1 |
| Marit, G | 1 |
| Maraninchi, D | 1 |
| Guyotat, D | 1 |
| Kuentz, M | 1 |
| Cordonnier, C | 1 |
| Reiffers, J | 1 |
| Van Loon, JA | 1 |
| Lilleyman, JS | 1 |
| Weinshilboum, RM | 1 |
| Tilz, GP | 1 |
| Nigro, N | 1 |
| Schlumberger, JR | 1 |
| Rosenberg, EB | 1 |
| Herberman, RB | 1 |
| Levine, PH | 1 |
| Halterman, RH | 1 |
| McCoy, JL | 1 |
| Wunderlich, JR | 1 |
| Campbell, AC | 1 |
| Hersey, P | 1 |
| Harding, B | 1 |
| Hollingsworth, PM | 1 |
| Skinner, J | 1 |
| MacLennan, IC | 1 |
| Thomas, F | 1 |
| Owens, L | 1 |
| Thomas, J | 1 |
| Wolf, JS | 1 |
| Volk, M | 1 |
| Mendez, G | 1 |
| Lee, HM | 1 |
| Ahn, YS | 1 |
| Harrington, WJ | 1 |
| Seelman, RC | 1 |
| Eytel, CS | 1 |
| Hardisty, RM | 1 |
| Norman, PM | 1 |
| Storti, E | 1 |
| Traldi, A | 1 |
| Quaglino, D | 1 |
| Cohen, ML | 1 |
| Weiss, EB | 1 |
| Cook, ES | 1 |
| Nutini, LG | 1 |
| Hopf, U | 1 |
| Fateh-Moghadam, A | 1 |
| Land, W | 1 |
| Brendel, W | 1 |
| Brambilla, G | 1 |
| Caraceni, CE | 1 |
| Cavanna, M | 1 |
| Parodi, S | 1 |
| Stacher, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prophylactic Infusion of Donor Lymphocytes in Cord Blood Transplantation[NCT02328885] | Phase 1/Phase 2 | 17 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for azathioprine and Leukemia, Lymphoid
| Article | Year |
|---|---|
Pure red cell aplasia.
Topics: Anticonvulsants; Antitubercular Agents; Autoimmune Diseases; Azathioprine; Bone Marrow Cells; Fancon | 2000 |
2 trials available for azathioprine and Leukemia, Lymphoid
| Article | Year |
|---|---|
[Induction of tolerance of heterologous protein in therapy with antilymphocytic globulin in man].
Topics: Adolescent; Adult; Aged; Animals; Antilymphocyte Serum; Azathioprine; Corneal Transplantation; Derma | 1972 |
Clinical studies on the effects of imuran and vincristine in the treatment of leukaemia.
Topics: Adult; Azathioprine; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Leukemia; Le | 1968 |
19 other studies available for azathioprine and Leukemia, Lymphoid
| Article | Year |
|---|---|
SUCCESSFUL ALLOGENIC BONE MARROW TRANSPLANTATION IN MAN: CHIMERISM, INDUCED SPECIFIC TOLERANCE AND POSSIBLE ANTI-LEUKEMIC EFFECTS.
Topics: Antineoplastic Agents; Azathioprine; Bone Marrow Transplantation; Chimerism; Electrons; Genetic Dise | 1965 |
Assay of 6-thioguanine nucleotide, a major metabolite of azathioprine, 6-mercaptopurine and 6-thioguanine, in human red blood cells.
Topics: Azathioprine; Erythrocytes; Guanine Nucleotides; Humans; In Vitro Techniques; Leukemia, Lymphoid; Me | 1983 |
[Acute leukemia after kidney allotransplantation (author's transl)].
Topics: Adult; Azathioprine; Humans; Kidney Transplantation; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; M | 1980 |
When autoimmune hemolytic anemia complicates chronic lymphocytic leukemia.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Azathioprine; Chlorambucil; Female; Humans; Leukemia, Lymphoid; | 1978 |
Influence of prednisone and cytostatics on human blood B-, T- and O-lymphocytes in diseases.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Azathioprine; B-Lymphocytes; Child; Chlorambucil; Co | 1975 |
Allogeneic bone marrow transplantation in adults with acute lymphoblastic leukemia in first complete remission.
Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Graft vs Host Disease; Humans; Leukemi | 1988 |
Thiopurine pharmacogenetics in leukemia: correlation of erythrocyte thiopurine methyltransferase activity and 6-thioguanine nucleotide concentrations.
Topics: Adult; Azathioprine; Child; Erythrocytes; Female; Genotype; Guanine Nucleotides; Humans; Leukemia, L | 1987 |
Azathioprine and immunotherapy in children's acute leukaemia.
Topics: Azathioprine; Child; Child, Preschool; gamma-Globulins; Humans; Leukemia, Lymphoid | 1969 |
[Treatment of acute lymphoblastic leukemia during a remission by irradiation of the central nervous system and subsequent administration of 8 chemotherapeutic agents].
Topics: Adolescent; Adult; Alkaloids; Antineoplastic Agents; Azathioprine; Azirines; Child; Child, Preschool | 1966 |
Lymphocyte cytotoxicity reactions to leukemia-associated antigens in identical twins.
Topics: Adolescent; Adult; Aged; Antigens; Azathioprine; Child; Child, Preschool; Chromium Isotopes; Cycloph | 1972 |
Effects of anti-cancer agents on immunological status.
Topics: Animals; Antibody-Producing Cells; Antineoplastic Agents; Azathioprine; Cytotoxicity Tests, Immunolo | 1973 |
Differential effect of immunosuppressive agents on T and B lymphocytes.
Topics: Animals; Antilymphocyte Serum; Azathioprine; B-Lymphocytes; Bacterial Infections; Concanavalin A; De | 1974 |
Vincristine therapy of idiopathic and secondary thrombocytopenias.
Topics: Adult; Aged; Azathioprine; Blood Cell Count; Blood Platelets; Bone Marrow Diseases; Child; Cyclophos | 1974 |
Preliminary experience with rubidomycin in the treatment of acute lymphoblastic leukaemia resistant to other antimetabolites.
Topics: Adult; Antibiotics, Antineoplastic; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Humans; | 1967 |
Pneumocystitis carinii pneumonia: percutaneous lung biopsy and review of literature.
Topics: Adolescent; Adult; Agammaglobulinemia; Amphotericin B; Anuria; Azathioprine; Biopsy; Bis-Trimethylam | 1971 |
Counteraction of leukopenia caused by mechlorethamine and azathioprine.
Topics: Animals; Antineoplastic Agents; Azathioprine; Dogs; Erythrocyte Count; Female; Kidney Transplantatio | 1971 |
[Serologic studies of patients under treatment with xenogenous antilymphocyte globulin].
Topics: Adrenal Cortex Hormones; Agglutination Tests; Animals; Antibodies; Antibody Formation; Antilymphocyt | 1970 |
[Evaluation, in newborn Swiss mice, of the carcinogenic activity of some antineoplastic and immunosuppressive compounds].
Topics: Adenoma; Animals; Animals, Newborn; Antineoplastic Agents; Asparaginase; Azathioprine; Fluorouracil; | 1971 |
[Progress in the therapy of leukoses].
Topics: Antineoplastic Agents; Azathioprine; Busulfan; Chlorambucil; Cyclophosphamide; Daunorubicin; Humans; | 1970 |