Page last updated: 2024-10-23

azathioprine and Leprosy

azathioprine has been researched along with Leprosy in 5 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Leprosy: A chronic granulomatous infection caused by MYCOBACTERIUM LEPRAE. The granulomatous lesions are manifested in the skin, the mucous membranes, and the peripheral nerves. Two polar or principal types are lepromatous and tuberculoid.

Research Excerpts

ExcerptRelevanceReference
"Randomised controlled trial adding azathioprine to steroid treatment for leprosy reactions."9.24AZALEP a randomized controlled trial of azathioprine to treat leprosy nerve damage and Type 1 reactions in India: Main findings. ( Darlong, J; Govindharaj, P; John, AS; Kurian, R; Lockwood, DN; Sundarrao, P, 2017)
"Randomised controlled trial adding azathioprine to steroid treatment for leprosy reactions."5.24AZALEP a randomized controlled trial of azathioprine to treat leprosy nerve damage and Type 1 reactions in India: Main findings. ( Darlong, J; Govindharaj, P; John, AS; Kurian, R; Lockwood, DN; Sundarrao, P, 2017)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lockwood, DN1
Darlong, J1
Govindharaj, P1
Kurian, R1
Sundarrao, P1
John, AS1
Schram, ME1
Borgonjen, RJ1
Bik, CM1
van der Schroeff, JG1
van Everdingen, JJ1
Spuls, PI1
McLeod, JG2
Hargrave, JC2
Gye, RS2
Pollard, JD2
Walsh, JC1
Little, JM1
Booth, GC2
Loewenthal, J1
Adu, D1
Evans, DB1
Millard, PR1
Calne, RY1
Shwe, T1
Jopling, WH1

Reviews

1 review available for azathioprine and Leprosy

ArticleYear
Off-label use of azathioprine in dermatology: a systematic review.
    Archives of dermatology, 2011, Volume: 147, Issue:4

    Topics: Azathioprine; Dermatologic Agents; Female; Humans; Leprosy; Male; Off-Label Use; Randomized Controll

2011

Trials

1 trial available for azathioprine and Leprosy

ArticleYear
AZALEP a randomized controlled trial of azathioprine to treat leprosy nerve damage and Type 1 reactions in India: Main findings.
    PLoS neglected tropical diseases, 2017, Volume: 11, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Im

2017

Other Studies

3 other studies available for azathioprine and Leprosy

ArticleYear
Nerve grafting in leprosy.
    Brain : a journal of neurology, 1975, Volume: 98, Issue:2

    Topics: Adolescent; Adult; Australia; Azathioprine; Child; Female; Humans; Immunosuppression Therapy; Lepros

1975
Use of immunosuppressive agents in human nerve grafting.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Adolescent; Adult; Azathioprine; Humans; Leprosy; Median Nerve; Methods; Peripheral Nerve Injuries;

1972
Renal transplantation in leprosy.
    British medical journal, 1973, May-05, Volume: 2, Issue:5861

    Topics: Adult; Azathioprine; Graft Rejection; Humans; Hydrocortisone; Immunosuppression Therapy; Kidney Fail

1973