azathioprine has been researched along with Leg Ulcer in 14 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Leg Ulcer: Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Despite intensive therapies including corticosteroids and azathioprine, marked progression of the ulcers was noted and large areas of necrosis appeared." | 3.78 | [Cutaneous polyarteritis nodosa--is it really benign?]. ( Berman, E; Halevy, S; Horev, A; Shavit, E, 2012) |
| "High doses of orally administered prednisolone induced the healing of the pyoderma gangrenosum within 2 months." | 3.70 | [Extra-intestinal manifestations and complications in chronic active ulcerative colitis in childhood and adolescence]. ( Hüppe, D; Schenck, B; Tromm, A, 1999) |
| "Leg ulcerations can occur in systemic lupus erythematosus (SLE) patients with antiphospholipid (aPL) antibodies and/or vasculitis, and it has been suggested that aPL antibodies may play a pathogenetic role in skin manifestations of SLE." | 1.34 | Lupus and leg ulcers--a diagnostic quandary. ( Boyce, S; Dziadzio, M; Hamdulay, S; Keat, A; Prasad, N; Reddy, V, 2007) |
| "Collagenous colitis is one of the microscopic colitides, which are thought to be on the same spectrum of disease as Crohn's disease and ulcerative colitis." | 1.32 | Pyoderma gangrenosum in a patient with collagenous colitis. ( Batra, AK; Levey, JM; Patwardhan, R; Trister, J, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (35.71) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, CH | 1 |
| Huang, YH | 1 |
| Shih, YC | 1 |
| Tseng, FW | 1 |
| Yang, CH | 1 |
| Rozin, AP | 1 |
| Egozi, D | 1 |
| Ramon, Y | 1 |
| Toledano, K | 1 |
| Braun-Moscovici, Y | 1 |
| Markovits, D | 1 |
| Schapira, D | 1 |
| Bergman, R | 1 |
| Melamed, Y | 1 |
| Ullman, Y | 1 |
| Balbir-Gurman, A | 1 |
| Shavit, E | 1 |
| Horev, A | 1 |
| Berman, E | 1 |
| Halevy, S | 1 |
| Batra, AK | 1 |
| Levey, JM | 1 |
| Trister, J | 1 |
| Patwardhan, R | 1 |
| Burgess, MJ | 1 |
| Robson, K | 1 |
| Chaffins, M | 1 |
| Reddy, V | 1 |
| Dziadzio, M | 1 |
| Hamdulay, S | 1 |
| Boyce, S | 1 |
| Prasad, N | 1 |
| Keat, A | 1 |
| García Acebes, CR | 1 |
| Barchino Ortiz, L | 1 |
| Aboín González, S | 1 |
| Díaz Ley, B | 1 |
| Ruiz Fernández, P | 1 |
| Sánchez de Paz, F | 1 |
| Lamberty, BG | 1 |
| Procházka, V | 1 |
| Rozkovcová, J | 1 |
| Bühler-Singer, S | 1 |
| von Hintzenstern, J | 1 |
| Fartasch, M | 1 |
| Hornstein, OP | 1 |
| Hüppe, D | 1 |
| Schenck, B | 1 |
| Tromm, A | 1 |
| Nurse, DS | 1 |
| Graybill, JR | 1 |
| Silva, J | 1 |
| Fraser, DW | 1 |
| Lordon, R | 1 |
| Rogers, E | 1 |
| Braun-Falco, O | 1 |
| Meigel, W | 1 |
1 review available for azathioprine and Leg Ulcer
| Article | Year |
|---|---|
[Mycobacterium marinum infection. Case report and review of the literature].
Topics: Aged; Anti-Bacterial Agents; Azathioprine; Doxycycline; Foot Injuries; Foot Ulcer; Humans; Immunocom | 2006 |
13 other studies available for azathioprine and Leg Ulcer
| Article | Year |
|---|---|
Sarcoidosis with cutaneous granulomatous vasculitis.
Topics: Adult; Azathioprine; Granuloma, Giant Cell; Humans; Leg Ulcer; Male; Prednisolone; Sarcoidosis; Syst | 2010 |
Large leg ulcers due to autoimmune diseases.
Topics: Animals; Antibodies, Monoclonal; Autoimmune Diseases; Azathioprine; Ciprofloxacin; Cyclophosphamide; | 2011 |
[Cutaneous polyarteritis nodosa--is it really benign?].
Topics: Amputation, Surgical; Arteries; Azathioprine; Biopsy; Disease Progression; Fatal Outcome; Female; Fl | 2012 |
Pyoderma gangrenosum in a patient with collagenous colitis.
Topics: Administration, Oral; Aged; Azathioprine; Colitis; Diagnosis, Differential; Diarrhea; Female; Humans | 2003 |
Lower extremity ulceration in an immunocompromised patient.
Topics: Aged; Azathioprine; Cryptococcosis; Glucocorticoids; Hepatitis, Autoimmune; Humans; Immunocompromise | 2004 |
Lupus and leg ulcers--a diagnostic quandary.
Topics: Adult; Azathioprine; Drug Therapy, Combination; Glucocorticoids; Humans; Immunosuppressive Agents; L | 2007 |
Pyoderma gangrenosum: report of an unusual case and a review of the literature.
Topics: Azathioprine; Female; Humans; Leg Ulcer; Middle Aged; Necrosis; Prednisolone; Pyoderma; Skin; Staphy | 1981 |
[Pyoderma gangrenosum. Successful treatment with the Imuran and prednisone combination (author's transl)].
Topics: Adult; Azathioprine; Colitis, Ulcerative; Drug Therapy, Combination; Female; Gangrene; Humans; Leg U | 1981 |
[Anticardiolipin syndrome with only skin involvement].
Topics: Adult; Antibodies, Anticardiolipin; Antiphospholipid Syndrome; Arm; Aspirin; Azathioprine; Combined | 1994 |
[Extra-intestinal manifestations and complications in chronic active ulcerative colitis in childhood and adolescence].
Topics: Adolescent; Azathioprine; Budesonide; Child; Colitis, Ulcerative; Diagnosis, Differential; Drug Ther | 1999 |
Livedo reticularis with ulceration: response to azathioprine therapy.
Topics: Azathioprine; Drug Therapy, Combination; Humans; Leg Dermatoses; Leg Ulcer; Male; Middle Aged; Predn | 1974 |
Disseminated mycobacteriosis due to Mycobacterium abcessus in two recipients of renal homografts.
Topics: Abscess; Adolescent; Adult; Azathioprine; Cross Infection; Dactinomycin; Female; Humans; Immunosuppr | 1974 |
[Azathioprine therapy of idiopathic ulcerating livedo racemosa].
Topics: Adult; Azathioprine; Biopsy; Female; Humans; Leg Ulcer; Middle Aged; Skin | 1972 |