Page last updated: 2024-10-23

azathioprine and Latent Tuberculosis

azathioprine has been researched along with Latent Tuberculosis in 11 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Latent Tuberculosis: The dormant form of TUBERCULOSIS where the person shows no obvious symptoms and no sign of the causative agent (Mycobacterium tuberculosis) in the SPUTUM despite being positive for tuberculosis infection skin test.

Research Excerpts

ExcerptRelevanceReference
"Isoniazid was prescribed to 684 (66."1.72Screening for latent tuberculosis before starting TNF-alpha inhibitors in a population with high BCG vaccination rates. ( Borekci, S; Celik, AF; Esatoglu, SN; Fresko, I; Hacioglu, A; Hamuryudan, V; Hatemi, G; Hatemi, I; Melikoglu, M; Ongen, HG; Ozdogan, H; Ozguler, Y; Seyahi, E; Ugurlu, S; Yurdakul, S, 2022)
"We report a rare case of Takayasu's arteritis with isolated pulmonary artery stenosis in the presence of active hepatitis B and latent Mycobacterium tuberculosis infection in a middle-aged Asian woman who initially presented with severe dyspnea on exertion and recurrent syncope, occasional burning chest pains, and fatigue."1.46Takayasu's Arteritis with Isolated Pulmonary Artery Involvement in a Middle-Aged Asian Woman with Hepatitis B and Latent Tuberculosis Infection. ( Franzen, D; Greutmann, M; Kolios, A; Liebscher, F; Pfammatter, T, 2017)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (90.91)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Hacioglu, A1
Borekci, S1
Melikoglu, M1
Ozguler, Y1
Esatoglu, SN1
Ugurlu, S1
Seyahi, E1
Fresko, I1
Hamuryudan, V1
Ozdogan, H1
Yurdakul, S1
Hatemi, I1
Celik, AF1
Ongen, HG1
Hatemi, G1
Chan, W1
Shim, HH1
Ng, SC1
Liu, J1
Inglis, C1
Greveson, K2
Baraty, B1
Haifer, C1
Leong, RWL1
Guirao-Arrabal, E1
Santos, F1
Redel-Montero, J1
Vaquero, JM1
Cantisán, S1
Vidal, E1
Torre-Giménez, Á1
Rivero, A1
Torre-Cisneros, J1
Liebscher, F1
Pfammatter, T1
Kolios, A1
Greutmann, M1
Franzen, D1
Reenaers, C1
Belaiche, J1
Louis, E1
Kwakernaak, AJ1
Houtman, PM1
Weel, JF1
Spoorenberg, JP1
Jansen, TL1
Znaor, L1
Medic, A1
Karaman, K1
Perkovic, D1
Rudd, A1
Dolianitis, C1
Varigos, G1
Howard, A1
Campainha, S1
Gomes, T1
Carvalho, A1
Duarte, R1
Goodhand, J1
Capocci, S1
Woodward, S1
Murray, C1
Cropley, I1
Hamilton, M1
Lipman, M1
Byun, JM1
Lee, CK1
Rhee, SY1
Kim, HJ1
Kim, JW1
Shim, JJ1
Jang, JY1

Other Studies

11 other studies available for azathioprine and Latent Tuberculosis

ArticleYear
Screening for latent tuberculosis before starting TNF-alpha inhibitors in a population with high BCG vaccination rates.
    Rheumatology international, 2022, Volume: 42, Issue:8

    Topics: Adult; Azathioprine; BCG Vaccine; Humans; Isoniazid; Latent Tuberculosis; Male; Prednisolone; Reprod

2022
A Global Survey of Gastroenterologists' Travel Advice to Patients with Inflammatory Bowel Disease on Immunosuppressive Agents and Management of Those Visiting Tuberculosis-Endemic Areas.
    Journal of Crohn's & colitis, 2018, Nov-15, Volume: 12, Issue:11

    Topics: Antibodies, Monoclonal, Humanized; Azathioprine; Diarrhea; Directive Counseling; Endemic Diseases; G

2018
Risk of tuberculosis after lung transplantation: the value of pretransplant chest computed tomography and the impact of mTOR inhibitors and azathioprine use.
    Transplant infectious disease : an official journal of the Transplantation Society, 2016, Volume: 18, Issue:4

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Everolimus; Female; Humans; Immunosu

2016
Takayasu's Arteritis with Isolated Pulmonary Artery Involvement in a Middle-Aged Asian Woman with Hepatitis B and Latent Tuberculosis Infection.
    Respiration; international review of thoracic diseases, 2017, Volume: 93, Issue:3

    Topics: Angiography, Digital Subtraction; Antitubercular Agents; Antiviral Agents; Azathioprine; Female; Flu

2017
Should patients under long-term anti-TNF therapies be followed for tuberculosis contamination?
    Inflammatory bowel diseases, 2010, Volume: 16, Issue:8

    Topics: Adalimumab; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Colitis,

2010
A comparison of an interferon-gamma release assay and tuberculin skin test in refractory inflammatory disease patients screened for latent tuberculosis prior to the initiation of a first tumor necrosis factor α inhibitor.
    Clinical rheumatology, 2011, Volume: 30, Issue:4

    Topics: Arthritis, Rheumatoid; Azathioprine; Biological Assay; CD4-Positive T-Lymphocytes; Female; Glucocort

2011
Serpiginous-like choroiditis as sign of intraocular tuberculosis.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:7

    Topics: Adult; Antitubercular Agents; Azathioprine; Choroiditis; Humans; Immunosuppressive Agents; Latent Tu

2011
A case of multicentric reticulohistiocytosis responsive to azathioprine in a patient with no underlying malignancy.
    The Australasian journal of dermatology, 2011, Volume: 52, Issue:4

    Topics: Antitubercular Agents; Azathioprine; Histiocytosis, Non-Langerhans-Cell; Humans; Immunosuppressive A

2011
Negative predictive value of TST and IGRA in anti-TNF treated patients.
    The European respiratory journal, 2012, Volume: 40, Issue:3

    Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Drug Therapy, Combination; Femal

2012
Yield and cost effectiveness of mycobacterial infection detection using a simple IGRA-based protocol in UK subjects with inflammatory bowel disease suitable for anti-TNFα therapy.
    Journal of Crohn's & colitis, 2013, Volume: 7, Issue:5

    Topics: Adalimumab; Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanize

2013
The risk of tuberculosis in Korean patients with inflammatory bowel disease receiving tumor necrosis factor-α blockers.
    Journal of Korean medical science, 2015, Volume: 30, Issue:2

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Cohort Studies; Colitis, Ulc

2015