azathioprine has been researched along with Lambert-Eaton Myasthenic Syndrome in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Lambert-Eaton Myasthenic Syndrome: An autoimmune disease characterized by weakness and fatigability of proximal muscles, particularly of the pelvic girdle, lower extremities, trunk, and shoulder girdle. There is relative sparing of extraocular and bulbar muscles. CARCINOMA, SMALL CELL of the lung is a frequently associated condition, although other malignancies and autoimmune diseases may be associated. Muscular weakness results from impaired impulse transmission at the NEUROMUSCULAR JUNCTION. Presynaptic calcium channel dysfunction leads to a reduced amount of acetylcholine being released in response to stimulation of the nerve. (From Adams et al., Principles of Neurology, 6th ed, pp 1471)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Myasthenia gravis is a rare, auto-immune neuromuscular junction disorder." | 2.44 | [Myasthenia gravis]. ( Fleury, MC; Tranchant, C, 2008) |
| "The case of a patient with fatigable diplopia and ptosis 3 years after removal of a large-cell lung carcinoma is presented." | 1.31 | Myasthenia gravis with a paraneoplastic marker. ( Leavitt, JA, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 5 (62.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Portaro, S | 1 |
| Brizzi, T | 1 |
| Sinicropi, S | 1 |
| Cacciola, A | 1 |
| De Cola, MC | 1 |
| Bramanti, A | 1 |
| Milardi, D | 1 |
| Lupica, A | 1 |
| Bramanti, P | 1 |
| Toscano, A | 1 |
| Rodolico, C | 1 |
| Kostera-Pruszczyk, A | 1 |
| Ryniewicz, B | 1 |
| Rowinska-Marcinska, K | 1 |
| Dutkiewicz, M | 1 |
| Kamińska, A | 1 |
| Fleury, MC | 1 |
| Tranchant, C | 1 |
| Guevara, C | 1 |
| Pedraza, L | 1 |
| Idiáquez, J | 1 |
| Delgado, M | 1 |
| Skeie, GO | 1 |
| Apostolski, S | 1 |
| Evoli, A | 1 |
| Gilhus, NE | 1 |
| Hart, IK | 1 |
| Harms, L | 1 |
| Hilton-Jones, D | 1 |
| Melms, A | 1 |
| Verschuuren, J | 1 |
| Horge, HW | 1 |
| Newsom-Davis, J | 1 |
| Leavitt, JA | 1 |
| Sieb, JP | 1 |
| Dengler, R | 1 |
| Jerusalem, F | 1 |
1 review available for azathioprine and Lambert-Eaton Myasthenic Syndrome
| Article | Year |
|---|---|
[Myasthenia gravis].
Topics: Adrenal Cortex Hormones; Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Azat | 2008 |
7 other studies available for azathioprine and Lambert-Eaton Myasthenic Syndrome
| Article | Year |
|---|---|
Five years experience on 3,4-diaminopyridine phosphate in Lambert-Eaton syndrome: Case reports.
Topics: 4-Aminopyridine; Activities of Daily Living; Adult; Amifampridine; Azathioprine; Drug Therapy, Combi | 2017 |
Lambert-Eaton myasthenic syndrome in childhood.
Topics: Autoantibodies; Azathioprine; Calcium Channels, P-Type; Child; Humans; Immunosuppressive Agents; Lam | 2009 |
[Idiopathic Lambert-Eaton myasthenic syndrome: report of one case].
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Humans; Immunosuppressive Agents; Lambert-Eaton Myast | 2006 |
Guidelines for the treatment of autoimmune neuromuscular transmission disorders.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases of the Nervous System; Azathioprine; Humans; Immunosupp | 2006 |
A treatment algorithm for Lambert-Eaton myasthenic syndrome.
Topics: 4-Aminopyridine; Algorithms; Amifampridine; Azathioprine; Carcinoma, Small Cell; Clinical Protocols; | 1998 |
Myasthenia gravis with a paraneoplastic marker.
Topics: Autoantibodies; Azathioprine; Biomarkers; Blepharoptosis; Calcium Channels; Carcinoma, Large Cell; D | 2000 |
[Non-neoplastic Lambert-Eaton syndrome. A frequently missed diagnosis?].
Topics: Adult; Azathioprine; Diagnosis, Differential; Electric Stimulation; Female; Humans; Lambert-Eaton My | 1992 |