azathioprine has been researched along with Koch's Disease in 25 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of isoniazid (INAH) prophylaxis against tuberculosis (TB) in patients taking corticosteroid remains controversial." | 7.73 | Tuberculosis in systemic lupus erythematosus in an endemic area and the role of isoniazid prophylaxis during corticosteroid therapy. ( Chan, TM; Lau, CS; Lo, Y; Mok, MY; Wong, WS, 2005) |
| "We report the third case in the literature of a patient with a long-lasting renal allograft who experienced tuberculosis just after the switch from azathioprine to mycophenolate mofetil." | 7.73 | Tuberculosis after conversion from azathioprine to mycophenolate mofetil in a long-term renal transplant recipient. ( Deray, G; Foltz, V; Isnard-Bagnis, C; Mercadal, L; Ourahma, S, 2005) |
| "The efficacy of isoniazid (INAH) prophylaxis against tuberculosis (TB) in patients taking corticosteroid remains controversial." | 3.73 | Tuberculosis in systemic lupus erythematosus in an endemic area and the role of isoniazid prophylaxis during corticosteroid therapy. ( Chan, TM; Lau, CS; Lo, Y; Mok, MY; Wong, WS, 2005) |
| "We report the third case in the literature of a patient with a long-lasting renal allograft who experienced tuberculosis just after the switch from azathioprine to mycophenolate mofetil." | 3.73 | Tuberculosis after conversion from azathioprine to mycophenolate mofetil in a long-term renal transplant recipient. ( Deray, G; Foltz, V; Isnard-Bagnis, C; Mercadal, L; Ourahma, S, 2005) |
| " TB risk was higher when anti-TNF agents were combined with methotrexate or azathioprine as compared with either controls (24/4241 versus 0/4673; OR 54; 95% CI 5." | 2.50 | Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials. ( Armuzzi, A; Bruzzese, V; Diamanti, AP; Gatta, L; Hassan, C; Laganà, B; Lorenzetti, R; Migliore, A; Ridola, L; Zullo, A, 2014) |
| "The treatment with azathioprine caused a relative depression of specific resistance accompanied by less pronounced inhibition of migration in vitro." | 1.25 | Specific acquired resistance and activity of migration inhibition factor (MIF) in spleens of mice with chronic tuberculosis. ( Kvapilová, M; Pekárek, J; Svejcar, J; Trnka, L, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (40.00) | 18.7374 |
| 1990's | 3 (12.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 6 (24.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fortes, FML | 1 |
| Rocha, R | 1 |
| Santana, GO | 1 |
| Choi, SJ | 1 |
| Kim, MS | 1 |
| Kim, ES | 1 |
| Lee, J | 1 |
| Lee, JM | 1 |
| Choi, HS | 1 |
| Keum, B | 1 |
| Jeen, YT | 1 |
| Lee, HS | 1 |
| Chun, HJ | 1 |
| Kim, CD | 1 |
| Begun, J | 1 |
| Sparrow, M | 1 |
| Viana, LA | 1 |
| Cristelli, MP | 1 |
| Santos, DW | 1 |
| Tavares, MG | 1 |
| Dantas, MTC | 1 |
| Felipe, CR | 1 |
| Silva, HT | 1 |
| Pestana, JM | 1 |
| Lorenzetti, R | 1 |
| Zullo, A | 1 |
| Ridola, L | 1 |
| Diamanti, AP | 1 |
| Laganà, B | 1 |
| Gatta, L | 1 |
| Migliore, A | 1 |
| Armuzzi, A | 1 |
| Hassan, C | 1 |
| Bruzzese, V | 1 |
| Wu, PH | 1 |
| Lin, YT | 1 |
| Yang, YH | 1 |
| Lin, YC | 2 |
| Campainha, S | 1 |
| Gomes, T | 1 |
| Carvalho, A | 1 |
| Duarte, R | 1 |
| Skhiri, H | 1 |
| Guedri, Y | 1 |
| Souani, Y | 1 |
| Achour, A | 1 |
| Bouraoui, S | 1 |
| Frih, A | 1 |
| Dhia, BN | 1 |
| Elmay, M | 1 |
| Atasever, A | 1 |
| Bacakoglu, F | 1 |
| Toz, H | 1 |
| Basoglu, OK | 1 |
| Duman, S | 1 |
| Basak, K | 1 |
| Guzelant, A | 1 |
| Sayiner, A | 1 |
| Mok, MY | 1 |
| Lo, Y | 1 |
| Chan, TM | 1 |
| Wong, WS | 1 |
| Lau, CS | 1 |
| Mercadal, L | 1 |
| Foltz, V | 1 |
| Isnard-Bagnis, C | 1 |
| Ourahma, S | 1 |
| Deray, G | 1 |
| Averbakh, MM | 1 |
| Litvinov, VI | 1 |
| Markov, AN | 1 |
| Abramova, ZP | 1 |
| Kim, YH | 1 |
| Yoon, YR | 1 |
| Kim, YW | 1 |
| Shin, JG | 1 |
| Cha, IJ | 1 |
| Millar, JW | 1 |
| Horne, NW | 1 |
| Brude, E | 1 |
| Siefert, G | 1 |
| Steiger, H | 1 |
| Kvapilová, M | 1 |
| Trnka, L | 3 |
| Svejcar, J | 2 |
| Pekárek, J | 2 |
| Naqvi, SA | 1 |
| Hussain, M | 1 |
| Askari, H | 1 |
| Hashmi, A | 1 |
| Hussain, Z | 1 |
| Hussain, I | 1 |
| Hafiz, S | 1 |
| Yazdani, I | 1 |
| Rizvi, SA | 1 |
| Sharma, RK | 1 |
| Elhence, R | 1 |
| Kher, V | 1 |
| Naik, SR | 1 |
| Bhandari, M | 1 |
| Mourad, G | 1 |
| Soulillou, JP | 1 |
| Chong, G | 1 |
| Pouliquen, M | 1 |
| Hourmant, M | 1 |
| Mion, C | 1 |
| Müllerova, M | 2 |
| Nouza, K | 2 |
| Matousek, V | 1 |
| Gould, DB | 1 |
| Falcao, H | 1 |
| Galdabini, J | 1 |
| Aronson, SB | 1 |
| Becker, K | 1 |
2 reviews available for azathioprine and Koch's Disease
| Article | Year |
|---|---|
Higher risk of tuberculosis reactivation when anti-TNF is combined with immunosuppressive agents: a systematic review of randomized controlled trials.
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Azathioprine; Certolizumab Pe | 2014 |
The uvea.
Topics: Anaphylaxis; Animals; Azathioprine; Chlorambucil; Epidemiologic Methods; Humans; Methotrexate; Stero | 1969 |
23 other studies available for azathioprine and Koch's Disease
| Article | Year |
|---|---|
Thiopurines are an independent risk factor for active tuberculosis in inflammatory bowel disease patients.
Topics: Azathioprine; Humans; Immunosuppressive Agents; Inflammatory Bowel Diseases; Mercaptopurine; Purine | 2023 |
Higher risk of tuberculosis in combination therapy for inflammatory bowel disease: A nationwide population-based cohort study in South Korea.
Topics: Adaptive Immunity; Azathioprine; Biological Products; Cohort Studies; Drug Therapy, Combination; Fem | 2020 |
Positioning biologics-A case-based discussion: Ustekinumab.
Topics: Adult; Antibodies, Monoclonal; Australia; Azathioprine; Biosimilar Pharmaceuticals; Crohn Disease; D | 2018 |
Positioning biologics-A case-based discussion: Vedolizumab.
Topics: Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Biosimilar Pharmaceuticals; Crohn Disease; F | 2018 |
Influence of epidemiology, immunosuppressive regimens, clinical presentation, and treatment on kidney transplant outcomes of patients diagnosed with tuberculosis: A retrospective cohort analysis.
Topics: Abatacept; Adult; Azathioprine; Calcineurin Inhibitors; Cytomegalovirus Infections; Female; Follow-U | 2019 |
The increased risk of active tuberculosis disease in patients with dermatomyositis - a nationwide retrospective cohort study.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Cohort Studies; Databases, Factual; | 2015 |
Negative predictive value of TST and IGRA in anti-TNF treated patients.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Drug Therapy, Combination; Femal | 2012 |
Primary tuberculosis 1 year after conversion from azathioprine to mycophenolate in recipient kidney transplantation: a case report.
Topics: Adult; Azathioprine; Graft Rejection; Humans; Immunosuppressive Agents; Kidney Failure, Chronic; Kid | 2003 |
Tuberculosis in renal transplant recipients on various immunosuppressive regimens.
Topics: Adult; Azathioprine; Cyclosporine; Female; Humans; Immunosuppression Therapy; Immunosuppressive Agen | 2005 |
Tuberculosis in systemic lupus erythematosus in an endemic area and the role of isoniazid prophylaxis during corticosteroid therapy.
Topics: Adult; Antibiotic Prophylaxis; Antitubercular Agents; Azathioprine; Endemic Diseases; Female; Glucoc | 2005 |
Tuberculosis after conversion from azathioprine to mycophenolate mofetil in a long-term renal transplant recipient.
Topics: Antitubercular Agents; Azathioprine; Humans; Kidney Transplantation; Male; Middle Aged; Mycophenolic | 2005 |
[Immunodepressant study of the mechanisms of antitubercular immunity].
Topics: Animals; Azathioprine; Chloramphenicol; Cyclophosphamide; Immunity; Immunosuppressive Agents; Mice; | 1981 |
Effects of rifampin on cyclosporine disposition in kidney recipients with tuberculosis.
Topics: Adult; Antibiotics, Antitubercular; Azathioprine; Cyclosporine; Drug Interactions; Drug Therapy, Com | 1998 |
Tuberculosis in immunosuppressed patients.
Topics: Adult; Aged; Azathioprine; Chlorambucil; Drug Therapy, Combination; Female; Humans; Immunosuppressio | 1979 |
[Tetracycline influence on cell-mediated immunity (author's transl)].
Topics: Animals; Azathioprine; Cyclophosphamide; Drug Administration Schedule; Guinea Pigs; Immunity, Cellul | 1977 |
Specific acquired resistance and activity of migration inhibition factor (MIF) in spleens of mice with chronic tuberculosis.
Topics: Animals; Azathioprine; Cell Migration Inhibition; Chronic Disease; Immunity, Cellular; Immunosuppres | 1975 |
Is there a place for prophylaxis against tuberculosis following renal transplantation?
Topics: Adolescent; Adult; Azathioprine; Child; Cyclosporine; Female; Follow-Up Studies; Humans; Isoniazid; | 1992 |
Liver disease in renal transplant recipients.
Topics: Azathioprine; Cyclosporine; Drug Therapy, Combination; Follow-Up Studies; Granuloma; Hepatitis; Hepa | 1992 |
Transmission of Mycobacterium tuberculosis with renal allografts.
Topics: Azathioprine; Female; Humans; Immunosuppression Therapy; Kidney Diseases; Kidney Transplantation; Ma | 1985 |
Immunosuppression and experimental tuberculosis. II. The effects of immunosuppressive agents and antilymphocyte serum on the organ dissemination of mycobacteria and on the development of specific delayed hypersensitivity.
Topics: Animals; Antigens, Bacterial; Antilymphocyte Serum; Azathioprine; Azauridine; Cell Migration Inhibit | 1974 |
Letter: Isoniazid hepatotoxicity.
Topics: Adult; Azathioprine; Chemical and Drug Induced Liver Injury; Glomerulonephritis; Humans; Isoniazid; | 1973 |
Immunosuppression and experimental tuberculosis. I. The effects of immunosuppressive agents, antilymphocyte serum and antimacrophage serum on the survival of animals with subacute experimental tuberculosis.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Azauridine; Chloramphenicol; Cyclophosphamide; Female; | 1973 |
[Immunosuppressive therapy of chronic aggressive hepatitis].
Topics: Azathioprine; Chronic Disease; Cortisone; Cyclophosphamide; Female; Follow-Up Studies; Hepatitis; Hu | 1972 |