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azathioprine and Kidney Tubular Necrosis, Acute

azathioprine has been researched along with Kidney Tubular Necrosis, Acute in 21 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Kidney Tubular Necrosis, Acute: Acute kidney failure resulting from destruction of EPITHELIAL CELLS of the KIDNEY TUBULES. It is commonly attributed to exposure to toxic agents or renal ISCHEMIA following severe TRAUMA.

Research Excerpts

ExcerptRelevanceReference
" Recipients of first cadaveric kidney allografts were treated with tacrolimus+mycophenolate mofetil (MMF), cyclosporine oral solution (modified) (CsA)+MMF, or tacrolimus+azathioprine (AZA)."9.09Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidney transplantation: results at 2 years. ( Ahsan, N; Corwin, C; Danovitch, G; Fitzsimmons, WE; Gonwa, T; Halloran, P; Hardy, M; Johnson, C; Light, J; Metzger, R; Mulloy, L; Rocher, L; Salm, K; Scandling, J; Shield , C; Sorensen, J; Stegall, M; Tolzman, D; VanVeldhuisen, P; Wachs, M, 2001)
" Recipients of first cadaveric kidney allografts were treated with tacrolimus+mycophenolate mofetil (MMF), cyclosporine oral solution (modified) (CsA)+MMF, or tacrolimus+azathioprine (AZA)."5.09Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidney transplantation: results at 2 years. ( Ahsan, N; Corwin, C; Danovitch, G; Fitzsimmons, WE; Gonwa, T; Halloran, P; Hardy, M; Johnson, C; Light, J; Metzger, R; Mulloy, L; Rocher, L; Salm, K; Scandling, J; Shield , C; Sorensen, J; Stegall, M; Tolzman, D; VanVeldhuisen, P; Wachs, M, 2001)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199011 (52.38)18.7374
1990's7 (33.33)18.2507
2000's3 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Manrique, J1
Rossich, E1
Hernández Sierra, A1
Light, JA1
Biggers, JA1
Alijani, MR1
Smith, M1
Oddendino, K1
Flechner, SM1
Payne, WD4
Van Buren, C1
Kerman, R1
Kahan, BD1
Sutherland, DE4
Strand, M2
Fryd, DS3
Ferguson, RM2
Simmons, RL3
Ascher, NL3
Najarian, JS4
Malfi, B1
Picciotto, G1
Manzione, A1
Turello, E1
Squiccimarro, G1
Messina, M1
Segoloni, GP1
Troppmann, C1
Almond, PS1
Dunn, DL1
Gores, PF1
Gruessner, RW1
Matas, AJ1
Niaudet, P1
Jean, G1
Broyer, M1
Chatenoud, L1
Kitabayashi, K1
Munn, SR1
Sterioff, S1
Ritz, M1
Pascoe, MD1
Pontin, AR1
Kahn, D1
Jang, HJ1
Kim, SC1
Han, DJ1
Ahsan, N1
Johnson, C1
Gonwa, T1
Halloran, P1
Stegall, M1
Hardy, M1
Metzger, R1
Shield , C1
Rocher, L1
Scandling, J1
Sorensen, J1
Mulloy, L1
Light, J1
Corwin, C1
Danovitch, G1
Wachs, M1
VanVeldhuisen, P1
Salm, K1
Tolzman, D1
Fitzsimmons, WE1
Hong, CD1
Kapoor, BS1
First, MR1
Pollak, VE1
Alexander, JW1
el Mouaaouy, A1
Mellert, J1
Wetzel, T1
Hopt, UT1
Rasmussen, K1
Pedersen, E1
Fischer, J1
Kirste, G1
Keller, H1
Wilms, H1
Gonwa, TA1
Nghiem, DD1
Schulak, JA1
Corry, RJ1
Sollinger, HW1
Deierhoi, M1
Kalayoglu, M1
Belzer, FO1
Canafax, DM2
Strand, MH1
Sommer, BG1
Milford, EL1
Kirkman, RL1
Tilney, NL1
Strom, TB1
Carpenter, CB1

Trials

8 trials available for azathioprine and Kidney Tubular Necrosis, Acute

ArticleYear
Comparison of azathioprine-antilymphocyte globulin versus cyclosporine in renal transplantation.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1984, Volume: 3, Issue:6

    Topics: Antilymphocyte Serum; Azathioprine; Clinical Trials as Topic; Cyclosporins; Graft Rejection; Graft S

1984
Comparison of OKT3 and antithymocyte globulin as induction immunosuppressive agents in renal transplantation.
    Transplantation proceedings, 1996, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Azathioprine; Child; Creatinine; Cyclosporine; Female

1996
Is cyclosporine toxic to the transplanted kidney with acute tubular necrosis?
    Transplantation proceedings, 1998, Volume: 30, Issue:4

    Topics: Antilymphocyte Serum; Azathioprine; Creatinine; Cyclosporine; Drug Therapy, Combination; Female; Hum

1998
Conversion from cyclosporine to tacrolimus in renal allograft recipients with delayed graft function from severe acute tubular necrosis.
    Transplantation proceedings, 2000, Volume: 32, Issue:7

    Topics: Adult; Aged; Azathioprine; Cadaver; Cyclosporine; Drug Therapy, Combination; Female; Follow-Up Studi

2000
Randomized trial of tacrolimus plus mycophenolate mofetil or azathioprine versus cyclosporine oral solution (modified) plus mycophenolate mofetil after cadaveric kidney transplantation: results at 2 years.
    Transplantation, 2001, Jul-27, Volume: 72, Issue:2

    Topics: Administration, Oral; Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Black People; Cadaver;

2001
A single institution, randomized, prospective trial of cyclosporin versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.
    Annals of surgery, 1985, Volume: 201, Issue:2

    Topics: Adolescent; Adult; Antilymphocyte Serum; Aspartate Aminotransferases; Azathioprine; Clinical Trials

1985
Results of the Minnesota randomized prospective trial of cyclosporine versus azathioprine-antilymphocyte globulin for immunosuppression in renal allograft recipients.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 5, Issue:6

    Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Bacterial Infections; Clinical Trials as Topi

1985
Clinical experience with cyclosporine and azathioprine at Brigham and Women's Hospital.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 5, Issue:6

    Topics: Adult; Azathioprine; Cadaver; Clinical Trials as Topic; Cost-Benefit Analysis; Creatinine; Cyclospor

1985

Other Studies

13 other studies available for azathioprine and Kidney Tubular Necrosis, Acute

ArticleYear
[Multiple complications after renal transplantation].
    Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia, 2004, Volume: 24 Suppl 3

    Topics: Adult; Azathioprine; Cataract; Cholecystitis; Choledocholithiasis; Cyclosporine; Femur Head Necrosis

2004
Serum beta-2-microglobulin: an adjunctive monitoring test in renal transplantation.
    Proceedings of the Clinical Dialysis and Transplant Forum, 1980, Volume: 10

    Topics: Antilymphocyte Serum; Azathioprine; beta 2-Microglobulin; Beta-Globulins; Creatinine; Graft Rejectio

1980
The effect of cyclosporine on early graft function in human renal transplantation.
    Transplantation, 1983, Volume: 36, Issue:3

    Topics: Acute Kidney Injury; Azathioprine; Cyclosporins; Graft Survival; Humans; Kidney; Kidney Transplantat

1983
[99mTc-DTPA scintigraphy in renal transplantation. Limitations related to the immunosuppressor used].
    Minerva urologica e nefrologica = The Italian journal of urology and nephrology, 1993, Volume: 45, Issue:1

    Topics: Azathioprine; Cyclosporine; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Kidney

1993
Does acute tubular necrosis affect renal transplant outcome? The impact of rejection episodes.
    Transplantation proceedings, 1993, Volume: 25, Issue:1 Pt 2

    Topics: Adolescent; Adult; Antilymphocyte Serum; Azathioprine; Cyclosporine; Follow-Up Studies; Graft Reject

1993
Anti-OKT3 response following prophylactic treatment in paediatric kidney transplant recipients.
    Pediatric nephrology (Berlin, Germany), 1993, Volume: 7, Issue:3

    Topics: Adolescent; Antibodies, Anti-Idiotypic; Azathioprine; CD3 Complex; Child; Child, Preschool; Enzyme-L

1993
Fractional excretion of sodium after renal transplantation.
    Kidney international, 1979, Volume: 16, Issue:2

    Topics: Antilymphocyte Serum; Azathioprine; Graft Rejection; Humans; Kidney; Kidney Transplantation; Kidney

1979
Value of sonography for follow-up examination after allogenic kidney transplantation.
    Surgical endoscopy, 1991, Volume: 5, Issue:1

    Topics: Azathioprine; Cyclosporins; Graft Rejection; Humans; Immunosuppression Therapy; Kidney; Kidney Trans

1991
Doppler ultrasound in the diagnosis of renal allograft rejection and in monitoring the effect of treatment.
    Scandinavian journal of clinical and laboratory investigation, 1990, Volume: 50, Issue:1

    Topics: Azathioprine; Blood Flow Velocity; Cyclosporins; Graft Rejection; Humans; Kidney; Kidney Transplanta

1990
Does ATN influence renal transplant function negatively?
    Transplantation proceedings, 1988, Volume: 20, Issue:5

    Topics: Acute Kidney Injury; Azathioprine; Cyclosporins; Graft Survival; Humans; Ischemia; Kidney; Kidney Fu

1988
Cyclosporine use in early graft dysfunction.
    Transplantation proceedings, 1986, Volume: 18, Issue:2 Suppl 1

    Topics: Azathioprine; Cadaver; Creatinine; Cyclosporins; Graft Survival; Humans; Kidney; Kidney Transplantat

1986
Sequential antilymphocyte globulin cyclosporine therapy in cadaver renal transplantation.
    Transplantation proceedings, 1986, Volume: 18, Issue:2 Suppl 1

    Topics: Antilymphocyte Serum; Azathioprine; Cadaver; Cyclosporins; Drug Therapy, Combination; Graft Rejectio

1986
Cyclosporine in renal transplantation: a single institutional experience.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1985, Volume: 5, Issue:6

    Topics: Azathioprine; Blood Pressure; Cadaver; Cost-Benefit Analysis; Cyclosporins; Drug Evaluation; Follow-

1985