Page last updated: 2024-10-23

azathioprine and Keratosis

azathioprine has been researched along with Keratosis in 14 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Keratosis: Any horny growth such as a wart or callus.

Research Excerpts

ExcerptRelevanceReference
"We describe three patients with pemphigus vulgaris, who during treatment with low doses of immunosuppressive drugs developed persistent keratotic or vegetating skin lesions."1.27Persistent vegetating and keratotic lesions in patients with pemphigus vulgaris during immunosuppressive therapy. ( Faber, WR; Flinterman, J; Neumann, HA, 1983)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199010 (71.43)18.7374
1990's2 (14.29)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
White, JM1
Salisbury, JR1
Creamer, D1
Faber, WR1
Neumann, HA1
Flinterman, J1
Hermanns-Lê, T1
Piérard, GE1
Caforio, AL1
Fortina, AB1
Piaserico, S1
Alaibac, M1
Tona, F1
Feltrin, G1
Pompei, E1
Testolin, L1
Gambino, A1
Volta, SD1
Thiene, G1
Casarotto, D1
Peserico, A1
Symington, GR1
Mackay, IR1
Lambert, RP1
Taylor, AE1
Shuster, S1
Neumann, RA1
Knobler, RM1
Metze, D1
Jurecka, W1
Leibovici, V1
Zeidenbaum, M1
Goldenhersh, M1
Lennard, L1
Thomas, S1
Harrington, CI1
Maddocks, JL1
Westburg, SP1
Stone, OJ1
Macmillan, AL1
Roberts, SO1
Marshall, V1
Marshall, VC1
Paterson, WD1
Allen, BR1
Beveridge, GW1

Reviews

1 review available for azathioprine and Keratosis

ArticleYear
Disseminated superficial porokeratosis and immunosuppression.
    The British journal of dermatology, 1988, Volume: 119, Issue:3

    Topics: Aged; Azathioprine; Drug Eruptions; Humans; Immunosuppression Therapy; Keratosis; Male; Pemphigus; P

1988

Other Studies

13 other studies available for azathioprine and Keratosis

ArticleYear
Eczematous changes on the hands--quiz case. Diagnosis: "Mechanic's hands" as part of the antisynthetase syndrome.
    Archives of dermatology, 2005, Volume: 141, Issue:6

    Topics: Azathioprine; Biopsy, Needle; Drug Therapy, Combination; Eczema; Female; Follow-Up Studies; Hand Der

2005
Persistent vegetating and keratotic lesions in patients with pemphigus vulgaris during immunosuppressive therapy.
    The British journal of dermatology, 1983, Volume: 109, Issue:4

    Topics: Acantholysis; Aged; Azathioprine; Female; Humans; Immunosuppression Therapy; Keratosis; Male; Middle

1983
Azathioprine-induced skin peeling syndrome.
    Dermatology (Basel, Switzerland), 1997, Volume: 194, Issue:2

    Topics: Azathioprine; Cytoplasm; Desmosomes; Drug Eruptions; Female; Follow-Up Studies; Humans; Immunosuppre

1997
Skin cancer in heart transplant recipients: risk factor analysis and relevance of immunosuppressive therapy.
    Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3

    Topics: Age Distribution; Azathioprine; Carcinoma, Squamous Cell; Comorbidity; Cyclosporine; Drug Therapy, C

2000
Cancer and teratogenesis: infrequent occurrence after medical use of immunosuppressive drugs.
    Australian and New Zealand journal of medicine, 1977, Volume: 7, Issue:4

    Topics: Abnormalities, Drug-Induced; Adult; Aged; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous C

1977
Skin cancer after renal transplantation: the causal role of azathioprine.
    Acta dermato-venereologica, 1992, Volume: 72, Issue:2

    Topics: Adolescent; Adult; Aged; Azathioprine; Cocarcinogenesis; Female; Humans; Immunosuppression Therapy;

1992
Porokeratosis and immunosuppressive treatment for pemphigus foliaceus.
    Journal of the American Academy of Dermatology, 1988, Volume: 19, Issue:5 Pt 1

    Topics: Aged; Azathioprine; Female; Humans; Keratosis; Methylprednisolone; Pemphigus

1988
Skin cancer in renal transplant recipients is associated with increased concentrations of 6-thioguanine nucleotide in red blood cells.
    The British journal of dermatology, 1985, Volume: 113, Issue:6

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Drug Administration Schedule; Erythrocytes; Female; G

1985
Multiple cutaneous squamous cell carcinomas during immunosuppressive therapy.
    Archives of dermatology, 1973, Volume: 107, Issue:6

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Fluorouracil; Humans; Hyperplasia; Immunosuppressive

1973
Porokeratosis of Mibelli after renal transplantation.
    The British journal of dermatology, 1974, Volume: 90, Issue:1

    Topics: Adult; Antigens; Azathioprine; Female; Humans; Keratosis; Kidney Transplantation; Mouth Diseases; Po

1974
Premalignant and malignant skin tumours in immunosuppressed patients.
    Transplantation, 1974, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Cadaver; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyc

1974
Skin tumours in immunosuppressed patients.
    The Australian and New Zealand journal of surgery, 1973, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Allopurinol; Antineoplastic Agents; Azathioprine; Carcinoma, Basal Cell; Carcinom

1973
Norwegian scabies during immunosuppressive therapy.
    British medical journal, 1973, Oct-27, Volume: 4, Issue:5886

    Topics: Adult; Azathioprine; Disease Outbreaks; Humans; Keratosis; Male; Norway; Prednisolone; Scabies

1973