azathioprine has been researched along with Keratoacanthoma in 8 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.
Excerpt | Relevance | Reference |
---|---|---|
"However, the risk of acquiring skin cancer increases with the length of immunosuppressive therapy." | 2.67 | No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective. ( Blohmé, I; Larkö, O, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 7 (87.50) | 18.7374 |
1990's | 1 (12.50) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Blohmé, I | 1 |
Larkö, O | 1 |
Reeve, VE | 1 |
Greenoak, GE | 1 |
Gallagher, CH | 1 |
Canfield, PJ | 1 |
Wilkinson, FJ | 1 |
Jacobsson, S | 1 |
Linell, F | 1 |
Rausing, A | 1 |
Walder, BK | 1 |
Robertson, MR | 1 |
Jeremy, D | 1 |
Westburg, SP | 1 |
Stone, OJ | 1 |
Marshall, V | 1 |
Marshall, VC | 1 |
Lowney, ED | 1 |
1 trial available for azathioprine and Keratoacanthoma
Article | Year |
---|---|
No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective.
Topics: Azathioprine; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Foll | 1992 |
7 other studies available for azathioprine and Keratoacanthoma
Article | Year |
---|---|
Effect of immunosuppressive agents and sunscreens on UV carcinogenesis in the hairless mouse.
Topics: 4-Aminobenzoic Acid; Animals; Antibody Formation; Azathioprine; Carcinoma in Situ; Carcinoma, Squamo | 1985 |
Florid keratoacanthomas in a kidney transplant recipient. Case report.
Topics: Azathioprine; Carcinoma, Squamous Cell; Dactinomycin; Graft Rejection; Humans; Immunosuppression The | 1974 |
Skin cancer and immunosuppression.
Topics: Adult; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Immunosuppress | 1971 |
Multiple cutaneous squamous cell carcinomas during immunosuppressive therapy.
Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Fluorouracil; Humans; Hyperplasia; Immunosuppressive | 1973 |
Premalignant and malignant skin tumours in immunosuppressed patients.
Topics: Adolescent; Adult; Aged; Azathioprine; Cadaver; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyc | 1974 |
Skin tumours in immunosuppressed patients.
Topics: Adolescent; Adult; Allopurinol; Antineoplastic Agents; Azathioprine; Carcinoma, Basal Cell; Carcinom | 1973 |
Antimitotic drugs and aggressive squamous cell tumors.
Topics: Aged; Antineoplastic Agents; Azathioprine; Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Kerat | 1972 |