Page last updated: 2024-10-23

azathioprine and Keratoacanthoma

azathioprine has been researched along with Keratoacanthoma in 8 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Keratoacanthoma: A benign, non-neoplastic, usually self-limiting epithelial lesion closely resembling squamous cell carcinoma clinically and histopathologically. It occurs in solitary, multiple, and eruptive forms. The solitary and multiple forms occur on sunlight exposed areas and are identical histologically; they affect primarily white males. The eruptive form usually involves both sexes and appears as a generalized papular eruption.

Research Excerpts

ExcerptRelevanceReference
"However, the risk of acquiring skin cancer increases with the length of immunosuppressive therapy."2.67No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective. ( Blohmé, I; Larkö, O, 1992)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19907 (87.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Blohmé, I1
Larkö, O1
Reeve, VE1
Greenoak, GE1
Gallagher, CH1
Canfield, PJ1
Wilkinson, FJ1
Jacobsson, S1
Linell, F1
Rausing, A1
Walder, BK1
Robertson, MR1
Jeremy, D1
Westburg, SP1
Stone, OJ1
Marshall, V1
Marshall, VC1
Lowney, ED1

Trials

1 trial available for azathioprine and Keratoacanthoma

ArticleYear
No difference in skin cancer incidence with or without cyclosporine--a 5-year perspective.
    Transplantation proceedings, 1992, Volume: 24, Issue:1

    Topics: Azathioprine; Carcinoma in Situ; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyclosporine; Foll

1992

Other Studies

7 other studies available for azathioprine and Keratoacanthoma

ArticleYear
Effect of immunosuppressive agents and sunscreens on UV carcinogenesis in the hairless mouse.
    The Australian journal of experimental biology and medical science, 1985, Volume: 63 ( Pt 6)

    Topics: 4-Aminobenzoic Acid; Animals; Antibody Formation; Azathioprine; Carcinoma in Situ; Carcinoma, Squamo

1985
Florid keratoacanthomas in a kidney transplant recipient. Case report.
    Scandinavian journal of plastic and reconstructive surgery, 1974, Volume: 8, Issue:3

    Topics: Azathioprine; Carcinoma, Squamous Cell; Dactinomycin; Graft Rejection; Humans; Immunosuppression The

1974
Skin cancer and immunosuppression.
    Lancet (London, England), 1971, Dec-11, Volume: 2, Issue:7737

    Topics: Adult; Azathioprine; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Female; Humans; Immunosuppress

1971
Multiple cutaneous squamous cell carcinomas during immunosuppressive therapy.
    Archives of dermatology, 1973, Volume: 107, Issue:6

    Topics: Adult; Azathioprine; Carcinoma, Squamous Cell; Fluorouracil; Humans; Hyperplasia; Immunosuppressive

1973
Premalignant and malignant skin tumours in immunosuppressed patients.
    Transplantation, 1974, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Aged; Azathioprine; Cadaver; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Cyc

1974
Skin tumours in immunosuppressed patients.
    The Australian and New Zealand journal of surgery, 1973, Volume: 43, Issue:3

    Topics: Adolescent; Adult; Allopurinol; Antineoplastic Agents; Azathioprine; Carcinoma, Basal Cell; Carcinom

1973
Antimitotic drugs and aggressive squamous cell tumors.
    Archives of dermatology, 1972, Volume: 105, Issue:6

    Topics: Aged; Antineoplastic Agents; Azathioprine; Carcinoma, Squamous Cell; Cyclophosphamide; Humans; Kerat

1972