azathioprine has been researched along with Keratitis in 7 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Keratitis: Inflammation of the cornea.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypersensitivity mimicking gastroenteritis is a rare complication of azathioprine therapy for which the mechanism is unknown." | 7.69 | Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine. ( Astier, A; Autegarden, JE; Godeau, B; Leynadier, F; Paul, M; Schaeffer, A, 1995) |
| "Keratitis was noted in mice which were splenectomized and subsequently treated with immunosuppressive drugs." | 5.26 | Appearance of keratitis in laboratory mice: influence of azathioprine and meticorten. ( Barishak, RY; Kaplun, A, 1976) |
| "Hypersensitivity mimicking gastroenteritis is a rare complication of azathioprine therapy for which the mechanism is unknown." | 3.69 | Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine. ( Astier, A; Autegarden, JE; Godeau, B; Leynadier, F; Paul, M; Schaeffer, A, 1995) |
| "Atypical Cogan's syndrome is more commonly associated with systemic manifestations than typical disease, and may be refractory to immunosuppressive treatment." | 2.45 | Cogan's syndrome: present and future directions. ( Harney, S; Molloy, M; Murphy, G; Shanahan, F; Sullivan, MO, 2009) |
| "Keratitis was noted in mice which were splenectomized and subsequently treated with immunosuppressive drugs." | 1.26 | Appearance of keratitis in laboratory mice: influence of azathioprine and meticorten. ( Barishak, RY; Kaplun, A, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murphy, G | 1 |
| Sullivan, MO | 1 |
| Shanahan, F | 1 |
| Harney, S | 1 |
| Molloy, M | 1 |
| Godeau, B | 1 |
| Paul, M | 1 |
| Autegarden, JE | 1 |
| Leynadier, F | 1 |
| Astier, A | 1 |
| Schaeffer, A | 1 |
| Kaplun, A | 1 |
| Barishak, RY | 1 |
| Benitez, JT | 1 |
| Arsenault, MD | 1 |
| Licht, JM | 1 |
| Cohen, SD | 1 |
| Greenberg, RV | 1 |
| Paulsen, ME | 1 |
| Lavach, JD | 1 |
| Snyder, SP | 1 |
| Severin, GA | 1 |
| Eichenbaum, JD | 1 |
| Mackay, IR | 1 |
| Bignell, JL | 1 |
| Smith, PH | 1 |
| Crawford, BA | 1 |
| Astle, JN | 1 |
| Ellis, PP | 1 |
1 review available for azathioprine and Keratitis
| Article | Year |
|---|---|
Cogan's syndrome: present and future directions.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Dose-Response Relationship, Drug; Fatal Outcome; Femal | 2009 |
6 other studies available for azathioprine and Keratitis
| Article | Year |
|---|---|
Hypersensitivity to azathioprine mimicking gastroenteritis. Absence of recurrence with 6-mercaptopurine.
Topics: Adult; Azathioprine; Diagnosis, Differential; Diarrhea; Ear Diseases; Gastroenteritis; Humans; Kerat | 1995 |
Appearance of keratitis in laboratory mice: influence of azathioprine and meticorten.
Topics: Animals; Azathioprine; Female; Keratitis; Mice; Pentobarbital; Prednisone; Rodent Diseases | 1976 |
Evidence of central vestibulo-auditory dysfunction in atypical Cogan's syndrome: a case report.
Topics: Adult; Audiometry; Auditory Diseases, Central; Azathioprine; Drug Therapy, Combination; Electronysta | 1990 |
Nodular granulomatous episclerokeratitis in dogs: 19 cases (1973-1985).
Topics: Adrenal Cortex Hormones; Age Factors; Animals; Azathioprine; Conjunctiva; Cornea; Dog Diseases; Dogs | 1987 |
Prevention of corneal-graft failure with the immunosuppressive drug azathioprine.
Topics: Adolescent; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Azathioprine; Corneal Transplantation | 1967 |
Ocular complications in renal transplant patients.
Topics: Adolescent; Adult; Azathioprine; Blood Urea Nitrogen; Cataract; Child; Cyclophosphamide; Cytomegalov | 1974 |