Page last updated: 2024-10-23

azathioprine and Joint Diseases

azathioprine has been researched along with Joint Diseases in 9 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Joint Diseases: Diseases involving the JOINTS.

Research Excerpts

ExcerptRelevanceReference
"Eighty-five patients with Wegener's granulomatosis were studied for 21 years at the National Institutes of Health."3.75Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years. ( Fauci, AS; Haynes, BF; Katz, P; Wolff, SM, 1983)
"All but one of 28 patients with mixed connective tissue disease (MCTD) who were studied prospectively had arthralgia, and 15 of them had noticed joint swelling."1.26Articular manifestations of mixed connective tissue disease. ( Alarcón-Segovia, D; Hernández-Ortíz, J; Ramos-Niembro, F, 1979)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19908 (88.89)18.7374
1990's0 (0.00)18.2507
2000's1 (11.11)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goodemote, P1
Jamieson, B1
Hoffman, R1
Fauci, AS1
Haynes, BF1
Katz, P1
Wolff, SM1
Fontana, A1
Doll, B1
Joller, H1
Fasshauer, K1
Rath, I1
Matuchansky, C1
Ramos-Niembro, F1
Alarcón-Segovia, D1
Hernández-Ortíz, J1
Bosch, FH1
Meinders, AE1
Bailey, RR1
Armour, P1
Strachan, JC1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase I/II Trial of TNFR:Fc (Etanercept) in Patients With Wegener's Granulomatosis[NCT00001901]Phase 260 participants Interventional1999-02-28Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for azathioprine and Joint Diseases

ArticleYear
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
    Annals of internal medicine, 1983, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati

1983

Trials

1 trial available for azathioprine and Joint Diseases

ArticleYear
Wegener's granulomatosis: prospective clinical and therapeutic experience with 85 patients for 21 years.
    Annals of internal medicine, 1983, Volume: 98, Issue:1

    Topics: Adolescent; Adult; Aged; Azathioprine; Clinical Trials as Topic; Cyclophosphamide; Drug Administrati

1983

Other Studies

8 other studies available for azathioprine and Joint Diseases

ArticleYear
Clinical inquiries. Are DMARDs effective for rheumatologic diseases besides rheumatoid arthritis?
    The Journal of family practice, 2007, Volume: 56, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Ps

2007
[IgG-IgM cryoglobulinemia with a purpura-arthralgia-nephritis syndrome].
    Schweizerische medizinische Wochenschrift, 1982, Jan-02, Volume: 112, Issue:1

    Topics: Adult; Azathioprine; Blood Protein Disorders; Cryoglobulinemia; Cyclophosphamide; Female; Humans; Im

1982
[Comments on the indication of immunosuppressive long-term therapy in myasthenia gravis (author's transl)].
    Fortschritte der Neurologie-Psychiatrie, 1981, Volume: 49, Issue:3

    Topics: Azathioprine; Bone Marrow Diseases; Cholestasis, Intrahepatic; Cholinesterase Inhibitors; Humans; Jo

1981
Inflammatory bowel diseases 1977.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 26, Issue:2

    Topics: Azathioprine; Colitis, Ulcerative; Crohn Disease; Cromolyn Sodium; Diet; Eye Diseases; Humans; Joint

1977
Articular manifestations of mixed connective tissue disease.
    Arthritis and rheumatism, 1979, Volume: 22, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Arthritis, Rheumatoid; Azathioprine; Child; Female; Huma

1979
[General malaise, high fever and arthralgia as a rare side effect of azathioprine].
    Nederlands tijdschrift voor geneeskunde, 1985, Aug-17, Volume: 129, Issue:33

    Topics: Azathioprine; Drug Hypersensitivity; Fever; Glomerulonephritis; Humans; Joint Diseases; Male; Middle

1985
Letter: Acute arthralgia after high-dose intravenous methylprednisolone.
    Lancet (London, England), 1974, Oct-26, Volume: 2, Issue:7887

    Topics: Adult; Azathioprine; Drug Therapy, Combination; Female; Foreign-Body Reaction; Graft Rejection; Huma

1974
Steroid arthropathy.
    Proceedings of the Royal Society of Medicine, 1971, Volume: 64, Issue:7

    Topics: Adult; Azathioprine; Female; Femur Head; Hip Joint; Humans; Joint Diseases; Joint Prosthesis; Kidney

1971