Page last updated: 2024-10-23

azathioprine and Itching

azathioprine has been researched along with Itching in 24 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"We sought to determine the efficacy and tolerability of azathioprine in the treatment of chronic pruritus responsive to systemic corticosteroids."7.81Azathioprine treatment of intractable pruritus: A retrospective review. ( Maley, A; Swerlick, RA, 2015)
"Azathioprine (AZA) is an immunosuppressive drug that is widely used in the treatment of autoimmune diseases."5.51Severe cholestasis due to azathioprine in Behcet's disease. ( Gisi, K; Ispiroglu, M; Kantarceken, B; Sayar, H, 2019)
"Treatment of primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) with ursodeoxycholic acid (UDCA) has been in common use since 1985."4.81Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis. ( Holtmeier, J; Leuschner, U, 2001)
"We sought to determine the efficacy and tolerability of azathioprine in the treatment of chronic pruritus responsive to systemic corticosteroids."3.81Azathioprine treatment of intractable pruritus: A retrospective review. ( Maley, A; Swerlick, RA, 2015)
"Azathioprine (AZA) is an immunosuppressive drug that is widely used in the treatment of autoimmune diseases."1.51Severe cholestasis due to azathioprine in Behcet's disease. ( Gisi, K; Ispiroglu, M; Kantarceken, B; Sayar, H, 2019)
" The median dosage of MMF was 1180 mg/d at the end of follow-up."1.36Introduction of mycophenolate mofetil in maintenance liver transplant recipients: what can we expect? Results of a 10-year experience. ( Adham, M; Boillot, O; Dumortier, J; Guillaud, O; Pittau, G; Salandre, J; Scoazec, JY, 2010)
"Bullous pemphigoid is an autoimmune bullous dermatosis that can be preceded by a prodromal phase, usually lasting weeks to months, during which the cutaneous changes are dermatitic rather than bullous."1.27The prodrome of bullous pemphigoid. ( Amato, DA; Silverstein, J; Zitelli, J, 1988)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199016 (66.67)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's4 (16.67)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Drucker, AM1
Ellis, AG1
Bohdanowicz, M1
Mashayekhi, S1
Yiu, ZZN1
Rochwerg, B1
Di Giorgio, S1
Arents, BWM1
Burton, T1
Spuls, PI1
Küster, D1
Siegels, D1
Schmitt, J1
Flohr, C1
Céruti, H1
Kayem, G1
Guilbaud, L1
Dussaux, C1
Gervais, A1
Beaufrère, A1
Coffin, B1
Mandelbrot, L1
Maisonneuve, E1
Gisi, K1
Ispiroglu, M1
Kantarceken, B1
Sayar, H1
Maley, A1
Swerlick, RA1
Dumortier, J1
Guillaud, O1
Pittau, G1
Salandre, J1
Adham, M1
Scoazec, JY1
Boillot, O1
Appelman, M1
Wintzen, M1
Bailin, PL1
Matkaluk, RM1
Holtmeier, J1
Leuschner, U1
van Berge Henegouwen, GP1
Brandt, KH1
Schalm, SW1
Heathcote, J1
Ross, A1
Sherlock, S1
Cello, JP1
Brunner, G1
Norris, PG1
Hawk, JL1
Amato, DA1
Silverstein, J1
Zitelli, J1
Adams, D1
Clements, D1
Elias, E1
Warnes, TW1
Hofstetter, JR1
Realini, S1
Fontolliet, CH1
Gardiol, D1
Rosenoer, VM1
Gokim, G1
Gips, CH1
Rogers, AI1
Gewurz, H2
Moberg, A2
Simmons, R1
Pollara, B1
Soll, R1
Najarian, S1
Pickering, RJ1
Simmons, RL1
Good, RA1
Najarian, JS1
Alarcón-Segovia, D1
Mayorga-Cortés, A1
Wolpert, E1

Reviews

7 reviews available for azathioprine and Itching

ArticleYear
Systemic Immunomodulatory Treatments for Patients With Atopic Dermatitis: A Systematic Review and Network Meta-analysis.
    JAMA dermatology, 2020, 06-01, Volume: 156, Issue:6

    Topics: Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Cyclosporine; Dermatitis, Atopic; Dermatolog

2020
Cutaneous reactions to rheumatological drugs.
    Clinics in rheumatic diseases, 1982, Volume: 8, Issue:2

    Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Azathioprine; Cushing Syndrome; Cy

1982
Medical treatment of primary biliary cirrhosis and primary sclerosing cholangitis.
    Digestion, 2001, Volume: 64, Issue:3

    Topics: Azathioprine; Celiac Disease; Cholagogues and Choleretics; Cholangitis, Sclerosing; Drug Therapy, Co

2001
The treatment of primary biliary cirrhosis.
    Journal of clinical and hospital pharmacy, 1986, Volume: 11, Issue:2

    Topics: Adrenal Cortex Hormones; Antipruritics; Azathioprine; Celiac Disease; Chlorambucil; Colchicine; Cycl

1986
Treatment of primary biliary cirrhosis.
    Seminars in liver disease, 1985, Volume: 5, Issue:3

    Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine

1985
Management of patients with chronic obstructive jaundice.
    The Medical clinics of North America, 1972, Volume: 56, Issue:3

    Topics: Adrenal Cortex Hormones; Azathioprine; Bile Acids and Salts; Cholestasis; Chronic Disease; Diet Ther

1972
Therapeutic considerations in selected forms of acute and chronic liver disease.
    The Medical clinics of North America, 1971, Volume: 55, Issue:2

    Topics: Acute Disease; Age Factors; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Chroni

1971

Trials

1 trial available for azathioprine and Itching

ArticleYear
A prospective controlled trial of azathioprine in primary biliary cirrhosis.
    Gastroenterology, 1976, Volume: 70, Issue:5 PT.1

    Topics: Azathioprine; Clinical Trials as Topic; Female; Humans; Immunoglobulin M; Liver; Liver Cirrhosis, Bi

1976

Other Studies

16 other studies available for azathioprine and Itching

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Intrahepatic cholestasis of pregnancy associated with azathioprine: A case series.
    Journal of gynecology obstetrics and human reproduction, 2021, Volume: 50, Issue:4

    Topics: Adult; Azathioprine; Bile Acids and Salts; Cholagogues and Choleretics; Cholestasis, Intrahepatic; C

2021
Severe cholestasis due to azathioprine in Behcet's disease.
    BMJ case reports, 2019, Mar-31, Volume: 12, Issue:3

    Topics: Adult; Azathioprine; Behcet Syndrome; Chemical and Drug Induced Liver Injury; Cholestasis; Humans; I

2019
Azathioprine treatment of intractable pruritus: A retrospective review.
    Journal of the American Academy of Dermatology, 2015, Volume: 73, Issue:3

    Topics: Adult; Aged; Azathioprine; Chronic Disease; Cohort Studies; Dose-Response Relationship, Drug; Drug A

2015
Introduction of mycophenolate mofetil in maintenance liver transplant recipients: what can we expect? Results of a 10-year experience.
    Transplantation proceedings, 2010, Volume: 42, Issue:7

    Topics: Adult; Azathioprine; Cyclosporine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug

2010
Pruritus and leucocytoclastic vasculitis due to azathioprine.
    Dermatology (Basel, Switzerland), 2005, Volume: 210, Issue:4

    Topics: Azathioprine; Biopsy, Needle; Female; Follow-Up Studies; Humans; Immunohistochemistry; Middle Aged;

2005
[Current insights in the treatment of primary biliary cirrhosis].
    Nederlands tijdschrift voor geneeskunde, 1978, Apr-22, Volume: 122, Issue:16

    Topics: Azathioprine; Copper; Humans; Liver Cirrhosis, Biliary; Osteomalacia; Penicillamine; Pruritus; Vitam

1978
Cholestasis in ulcerative colitis. Long term complications and medical therapy.
    Gastroenterology, 1977, Volume: 73, Issue:2

    Topics: Anti-Bacterial Agents; Azathioprine; Bacterial Infections; Bile Acids and Salts; Cholangitis; Cholel

1977
[Therapy of the chronic destructive, non-purulent cholangitis (primary biliary cirrhosis)].
    Deutsche medizinische Wochenschrift (1946), 1976, Sep-03, Volume: 101, Issue:36

    Topics: Azathioprine; Calcium; Cholangitis; Cholestyramine Resin; Clofibrate; Humans; Hypercholesterolemia;

1976
Successful treatment of severe polymorphous light eruption with azathioprine.
    Archives of dermatology, 1989, Volume: 125, Issue:10

    Topics: Azathioprine; Erythema; Female; Humans; Middle Aged; Photosensitivity Disorders; Pruritus; PUVA Ther

1989
The prodrome of bullous pemphigoid.
    International journal of dermatology, 1988, Volume: 27, Issue:8

    Topics: Aged; Azathioprine; Biopsy; Dermatitis; Female; Fluorescent Antibody Technique; Humans; Middle Aged;

1988
[Primitive biliary cirrhosis. Difficulties of an early diagnosis].
    Schweizerische medizinische Wochenschrift, 1974, Dec-14, Volume: 104, Issue:50

    Topics: Adult; Aged; Autoantibodies; Azathioprine; Biopsy; Female; Humans; Liver; Liver Cirrhosis, Biliary;

1974
Reflections on the treatment of itch in primary biliary cirrhosis.
    The Netherlands journal of medicine, 1973, Volume: 16, Issue:3

    Topics: Adult; Azathioprine; Child, Preschool; Cholangitis; Cholestyramine Resin; Female; Humans; Phenobarbi

1973
Reactivities to horse anti-lymphocyte globulin. I. Induction of immunologic tolerance in man.
    International archives of allergy and applied immunology, 1970, Volume: 39, Issue:2-3

    Topics: Animals; Antibody Formation; Antilymphocyte Serum; Azathioprine; Fever; Hemagglutination Tests; Hors

1970
Reactivities to horse anti-lymphocyte globulin. II. Serum sickness nephritis with complement alterations in man.
    International archives of allergy and applied immunology, 1970, Volume: 39, Issue:2-3

    Topics: Antilymphocyte Serum; Azathioprine; Complement System Proteins; Fever; Glomerulonephritis; Hemagglut

1970
Primary biliary cirrhosis. Prompt relief of pruritus with azathioprine treatment.
    JAMA, 1970, Oct-12, Volume: 214, Issue:2

    Topics: Adult; Alanine Transaminase; Alkaline Phosphatase; Azathioprine; Bile Acids and Salts; Bilirubin; Bl

1970