Page last updated: 2024-10-23

azathioprine and Intestinal Perforation

azathioprine has been researched along with Intestinal Perforation in 20 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Intestinal Perforation: Opening or penetration through the wall of the INTESTINES.

Research Excerpts

ExcerptRelevanceReference
" The patients who achieved a complete remission with medical treatment, who had no history of intestinal perforation, and who received azathioprine after operation showed better clinical courses."3.70Long-term clinical course and prognostic factors in intestinal Behçet's disease. ( Cha, SD; Choi, IJ; Jung, HC; Kim, CY; Kim, JS; Park, JG; Song, IS, 2000)
"CASE REPORT A 57-year-old man with pemphigus vulgaris was treated with steroids, non-steroidal anti-inflammatory drugs (NSAIDS), and azathioprine."1.51Recurrent Asymptomatic Sigmoid Diverticular Perforation in a Patient with Pemphigus Vulgaris on Immunosuppressive Therapy: A Case Report. ( Abboud, R; El Masri, A; Emmanuel, N; Fawaz, M; Haidar Ahmad, H; Hashem, M; Hussein, R; Nicolas, G; Rabah, H; Saliba, C; Sleiman, A, 2019)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's1 (5.00)18.2507
2000's3 (15.00)29.6817
2010's7 (35.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kiboshi, T1
Isoda, K1
Furukawa, K1
Wakahara, T1
Otani, K1
Ueda, K1
Konma, J1
Teramura, K1
Ueno, N1
Fujiwara, H1
Shoda, T1
Saliba, C1
Rabah, H1
Nicolas, G1
Emmanuel, N1
Sleiman, A1
Hashem, M1
Hussein, R1
El Masri, A1
Abboud, R1
Fawaz, M1
Haidar Ahmad, H1
Narazaki, T1
Shiratsuchi, M1
Tsuda, M1
Tsukamoto, Y1
Muta, H1
Masuda, T1
Kimura, D1
Takamatsu, A1
Nakanishi, R1
Oki, E1
Fujiwara, M1
Oda, Y1
Nakashima, Y1
Ogawa, Y1
Yamamoto, T1
Watanabe, T1
Charlagorla, P1
Sublett, S1
Sy, F1
Kessler, E1
Gad, A1
Glushko, T1
Marcus, VA1
Colmegna, I1
Bang, S1
Park, YB1
Kang, BS1
Park, MC1
Hwang, MH1
Kim, HK1
Lee, SK1
Sasaki, J1
Kawamura, YJ1
Konishi, F1
Tosha, T1
Singleton, JW1
Ferrozzi, F1
Cadermartiri, F1
Choi, IJ1
Kim, JS1
Cha, SD1
Jung, HC1
Park, JG1
Song, IS1
Kim, CY1
Demling, RH1
Salvatierra, O1
Belzer, FO1
Canavan, JS1
Briggs, JD1
Bell, PR1
Aizawa, Y1
Komeji, S1
Irimajiri, S1
Abe, T1
Honma, M1
Powis, SJ1
Barnes, AD1
Dawson-Edwards, P1
Thompson, H1
Harket, R1
Fausa, O1
Nygaard, K1
Ashton, H1
Frenk, E1
Stevenson, CJ1
Williams, JA1
Kirsner, JB1
Ye, BD1
Yang, SK1
Shin, SJ1
Lee, KM1
Jang, BI1
Cheon, JH1
Choi, CH1
Kim, YH1
Lee, H1

Reviews

4 reviews available for azathioprine and Intestinal Perforation

ArticleYear
[Granulomatosis with Polyangiitis Complicated with Gastrointestinal Perforation: A Case Report and Review of Literature].
    Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology, 2017, Volume: 40, Issue:5

    Topics: Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Biomarkers; Cyclophosphamide; Early Diagnosis;

2017
Strategies for the prevention of postoperative recurrence of Crohn's disease.
    Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:12

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Azathioprine; Colectomy; Colon; Col

2013
Therapeutics. XV. The management of Henoch-Schonlein purpura.
    The British journal of dermatology, 1971, Volume: 85, Issue:2

    Topics: Adult; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Glucocorticoids; Humans; Hydrocortis

1971
The place of surgery in Crohn's disease.
    Gut, 1971, Volume: 12, Issue:9

    Topics: Abscess; Acute Disease; Anemia; Appendectomy; Azathioprine; Colectomy; Colonic Diseases; Crohn Disea

1971

Other Studies

16 other studies available for azathioprine and Intestinal Perforation

ArticleYear
Recurrent Asymptomatic Sigmoid Diverticular Perforation in a Patient with Pemphigus Vulgaris on Immunosuppressive Therapy: A Case Report.
    The American journal of case reports, 2019, May-24, Volume: 20

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Diverticulum, Colon; Humans; Immunosuppressiv

2019
Intestinal Behçet's Disease with Primary Myelofibrosis Involving Trisomy 8.
    Acta haematologica, 2019, Volume: 142, Issue:4

    Topics: Azathioprine; Behcet Syndrome; Chromosomes, Human, Pair 8; Female; Humans; Infliximab; Intestinal Pe

2019
Fetal intestinal perforation and meconium peritonitis associated with maternal autoimmune hepatitis.
    Journal of neonatal-perinatal medicine, 2014, Volume: 7, Issue:1

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Azathioprine; Enterococcus faecalis; Female; Gentamicins;

2014
Cytomegalovirus-induced Colon Perforation in Systemic Lupus Erythematosus.
    The Journal of rheumatology, 2016, Volume: 43, Issue:2

    Topics: Azathioprine; Colon; Cytomegalovirus; Cytomegalovirus Infections; Female; Humans; Immunocompromised

2016
CMV enteritis causing ileal perforation in underlying lupus enteritis.
    Clinical rheumatology, 2004, Volume: 23, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Antiviral Agents; Azathioprine; Cytomegalovirus; Cytomegalovirus In

2004
Colitic cancer developed after introduction of azathioprine.
    Digestive diseases and sciences, 2004, Volume: 49, Issue:10

    Topics: Adenocarcinoma; Adult; Azathioprine; Colitis, Ulcerative; Colonic Neoplasms; Colonoscopy; Fatal Outc

2004
Medical therapy of inflammatory bowel disease.
    The Medical clinics of North America, 1980, Volume: 64, Issue:6

    Topics: Acute Disease; Adjuvants, Immunologic; Anus Diseases; Azathioprine; Colitis, Ulcerative; Crohn Disea

1980
[Sigmoid perforation caused by drug-induced vasculitis: findings with computerized tomography. A case].
    La Radiologia medica, 1999, Volume: 97, Issue:5

    Topics: Aged; Azathioprine; Female; Humans; Immunosuppressive Agents; Intestinal Perforation; Sigmoid Diseas

1999
Long-term clinical course and prognostic factors in intestinal Behçet's disease.
    Diseases of the colon and rectum, 2000, Volume: 43, Issue:5

    Topics: Adolescent; Adult; Azathioprine; Behcet Syndrome; Colectomy; Colonic Diseases; Colonoscopy; Combined

2000
Intestinal necrosis and perforation after renal transplantation.
    Archives of surgery (Chicago, Ill. : 1960), 1975, Volume: 110, Issue:3

    Topics: Adult; Azathioprine; Humans; Immunosuppression Therapy; Intestinal Diseases; Intestinal Perforation;

1975
Gastric acid secretion following renal transplantation.
    The British journal of surgery, 1975, Volume: 62, Issue:9

    Topics: Adolescent; Adult; Azathioprine; Duodenal Ulcer; Dyspepsia; Female; Gastric Juice; Humans; Intestina

1975
[Effective use of azathioprine in a case of polyarteritis nodosa with recurrent intestinal perforation: a distinction between polyarteritis nodosa and allergic granulomatous angiitis].
    Nihon rinsho. Japanese journal of clinical medicine, 1974, Dec-10, Volume: 32, Issue:12

    Topics: Adult; Arteritis; Azathioprine; Diagnosis, Differential; Granuloma; Humans; Intestinal Perforation;

1974
Ileocolonic problems after cadaveric renal transplantation.
    British medical journal, 1972, Jan-08, Volume: 1, Issue:5792

    Topics: Acute Disease; Adult; Azathioprine; Cadaver; Colon; Colon, Sigmoid; Female; Humans; Ileum; Intestina

1972
Progressive occlusive endarteritis. A case report.
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1973, Volume: 81, Issue:6

    Topics: Adult; Arterial Occlusive Diseases; Arteries; Autopsy; Azathioprine; Coronary Vessels; Endarteritis;

1973
The challenges of ulcerative colitis.
    Postgraduate medicine, 1971, Volume: 49, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Anti-Bacterial Agents; Azathioprine; Blood Transfusion;

1971
[Guidelines for the management of Crohn's disease].
    The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi, 2012, Volume: 59, Issue:2

    Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antimetabolites, Antineoplastic; Budesonide; Crohn

2012