azathioprine has been researched along with Intestinal Obstruction in 17 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Intestinal Obstruction: Any impairment, arrest, or reversal of the normal flow of INTESTINAL CONTENTS toward the ANAL CANAL.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a case of 36-year-old Japanese man with Crohn's disease, complicated by Bacillus cereus bacteremia on maintenance azathioprine therapy." | 7.75 | [Bacillus cereus bacteremia in Crohn's disease with multiple ileal stricture on maintenance azathioprine therapy]. ( Hizawa, K; Iida, M; Matsumoto, T; Nagata, Y; Nakamori, M; Taniguchi, M, 2009) |
| "We describe a case of 36-year-old Japanese man with Crohn's disease, complicated by Bacillus cereus bacteremia on maintenance azathioprine therapy." | 3.75 | [Bacillus cereus bacteremia in Crohn's disease with multiple ileal stricture on maintenance azathioprine therapy]. ( Hizawa, K; Iida, M; Matsumoto, T; Nagata, Y; Nakamori, M; Taniguchi, M, 2009) |
| "Patients with subocclusive Crohn's disease (CD) who received azathioprine (AZA) therapy had lower re-hospitalization rates due to all causes and for surgical management of CD compared to those treated with mesalazine during a 3-year period." | 2.79 | Azathioprine is more effective than mesalazine at preventing recurrent bowel obstruction in patients with ileocecal Crohn's disease. ( Castro, AC; Chebli, JM; Chebli, LA; da Rocha Ribeiro, TC; de Lima Pace, FH; de Oliveira Zanini, KA; de Souza, GS; do Valle Pinheiro, B; Furtado, MC; Gaburri, PD; Machado de Oliveira, J; Pinto, AL; Ribeiro, LC; Vidigal, FM; Zanini, A, 2014) |
| " Since there was no activity of the mixed connective tissue disease the methylprednisolone dosage was reduced and the administration of azathioprine was ceased." | 2.39 | [Chronic recurrent subileus due to Strongyloides stercoralis infection under immunosuppressive therapy]. ( Back, W; Birck, R; Braun, C; Gottstein, T; Gretz, N; Manegold, BC; Rohmeiss, P; Strauch, M, 1996) |
| "Crohn's disease is a perplexing disease with a high rate of morbidity and complications." | 2.35 | The protean manifestations of Crohn's disease. ( Farmer, RG, 1975) |
| "Recurrent Crohn's disease and that characterized by small bowel obstruction each displayed a characteristic appearance." | 1.26 | Radiographic findings of the National Cooperative Crohn's Disease Study. ( Caruthers, SB; Goldberg, HI; Nelson, JA; Singleton, JW, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 1 (5.88) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 4 (23.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Vidigal, FM | 1 |
| de Souza, GS | 1 |
| Chebli, LA | 1 |
| da Rocha Ribeiro, TC | 1 |
| Furtado, MC | 1 |
| Castro, AC | 1 |
| Pinto, AL | 1 |
| do Valle Pinheiro, B | 1 |
| de Lima Pace, FH | 1 |
| Machado de Oliveira, J | 1 |
| de Oliveira Zanini, KA | 1 |
| Gaburri, PD | 1 |
| Zanini, A | 1 |
| Ribeiro, LC | 1 |
| Chebli, JM | 1 |
| Barnes, EL | 1 |
| Goldin, A | 1 |
| Winter, RW | 1 |
| Collins, E | 1 |
| Cao, B | 1 |
| Carrellas, M | 1 |
| Crowell, AM | 1 |
| Korzenik, JR | 1 |
| Hizawa, K | 1 |
| Nagata, Y | 1 |
| Taniguchi, M | 1 |
| Nakamori, M | 1 |
| Matsumoto, T | 1 |
| Iida, M | 1 |
| Dale, RC | 1 |
| Lang, B | 1 |
| Brilot, F | 1 |
| Polfrit, Y | 1 |
| Smith, GH | 1 |
| Wong, M | 1 |
| Gustavsson, A | 1 |
| Magnuson, A | 1 |
| Blomberg, B | 1 |
| Andersson, M | 1 |
| Halfvarson, J | 1 |
| Tysk, C | 1 |
| STARZL, TE | 1 |
| MARCHIORO, TL | 1 |
| DICKINSON, TC | 1 |
| RIFKIND, D | 1 |
| STONINGTON, OG | 1 |
| WADDELL, WR | 1 |
| Cosnes, J | 1 |
| Nion-Larmurier, I | 1 |
| Beaugerie, L | 1 |
| Afchain, P | 1 |
| Tiret, E | 1 |
| Gendre, JP | 1 |
| Storr, M | 1 |
| Göke, B | 1 |
| Wagner, A | 1 |
| Sigaroudinia, MO | 1 |
| Baillie, C | 1 |
| Ahmed, S | 1 |
| Mallucci, C | 1 |
| Birck, R | 1 |
| Braun, C | 1 |
| Back, W | 1 |
| Gottstein, T | 1 |
| Rohmeiss, P | 1 |
| Manegold, BC | 1 |
| Strauch, M | 1 |
| Gretz, N | 1 |
| Goldberg, HI | 1 |
| Caruthers, SB | 1 |
| Nelson, JA | 1 |
| Singleton, JW | 1 |
| Dölle, W | 1 |
| Herfarth, C | 1 |
| Farmer, RG | 1 |
| Bonardi, R | 1 |
| Javett, SL | 1 |
| Hoffmann, VJ | 1 |
| Schulz, HJ | 1 |
| Reitzig, P | 1 |
| Lisewski, G | 1 |
| Dietze, F | 1 |
| Davis, R | 1 |
| Schmaman, A | 1 |
| Cosman, B | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Surgery Versus Conservative Treatment in Patients With Ileocaecal Crohn's Disease - Prospective Randomized Study[NCT02716454] | 200 participants (Anticipated) | Interventional | 2016-05-31 | Not yet recruiting | |||
| Effect of Early Prescription of Immunosuppressants on First Three-year Course of Crohn's Disease[NCT00546546] | Phase 4 | 120 participants (Actual) | Interventional | 2005-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for azathioprine and Intestinal Obstruction
| Article | Year |
|---|---|
[Chronic recurrent subileus due to Strongyloides stercoralis infection under immunosuppressive therapy].
Topics: Adult; Animals; Azathioprine; Chronic Disease; Diagnosis, Differential; Drug Therapy, Combination; D | 1996 |
The protean manifestations of Crohn's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arthritis; Azathioprine; Child; Colectomy; Colitis, | 1975 |
2 trials available for azathioprine and Intestinal Obstruction
| Article | Year |
|---|---|
Azathioprine is more effective than mesalazine at preventing recurrent bowel obstruction in patients with ileocecal Crohn's disease.
Topics: Adult; Azathioprine; Crohn Disease; Demography; Female; Humans; Ileocecal Valve; Intestinal Obstruct | 2014 |
[Indications for surgical and conservative therapy of Crohn's disease].
Topics: Acute Disease; Azathioprine; Chronic Disease; Clinical Trials as Topic; Crohn Disease; Humans; Intes | 1977 |
13 other studies available for azathioprine and Intestinal Obstruction
| Article | Year |
|---|---|
Sequential Combination Therapy Versus Monotherapy: A Lack of Benefit in Time to Inflammatory Bowel Disease-Related Surgery.
Topics: Adalimumab; Adult; Antirheumatic Agents; Azathioprine; Case-Control Studies; Cohort Studies; Colitis | 2016 |
[Bacillus cereus bacteremia in Crohn's disease with multiple ileal stricture on maintenance azathioprine therapy].
Topics: Adult; Azathioprine; Bacillus cereus; Bacteremia; Crohn Disease; Humans; Ileal Diseases; Ileum; Immu | 2009 |
Treatment-responsive pandysautonomia in an adolescent with ganglionic α3-AChR antibodies.
Topics: Abdominal Pain; Adolescent; Anti-Inflammatory Agents; Antibodies; Autoimmune Diseases; Autonomic Ner | 2012 |
Smoking is a risk factor for recurrence of intestinal stricture after endoscopic dilation in Crohn's disease.
Topics: Adult; Azathioprine; Crohn Disease; Endoscopy; Female; Humans; Immunosuppressive Agents; Intestinal | 2013 |
TECHNIQUE OF RENAL HOMOTRANSPLANTATION. EXPERIENCE WITH 42 CASES.
Topics: Azathioprine; Dactinomycin; Diabetes Mellitus; Gastrointestinal Hemorrhage; Humans; Intestinal Obstr | 1964 |
Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery.
Topics: Adult; Azathioprine; Crohn Disease; Digestive System Surgical Procedures; Drug Administration Schedu | 2005 |
Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery.
Topics: Adult; Azathioprine; Crohn Disease; Digestive System Surgical Procedures; Drug Administration Schedu | 2005 |
Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery.
Topics: Adult; Azathioprine; Crohn Disease; Digestive System Surgical Procedures; Drug Administration Schedu | 2005 |
Impact of the increasing use of immunosuppressants in Crohn's disease on the need for intestinal surgery.
Topics: Adult; Azathioprine; Crohn Disease; Digestive System Surgical Procedures; Drug Administration Schedu | 2005 |
An unusual cause of azathioprine inefficacy.
Topics: Azathioprine; Catheterization; Colon; Colonoscopy; Crohn Disease; Drug Packaging; Female; Foreign Bo | 2006 |
Sclerosing encapsulating peritonitis--a rare complication of ventriculoperitoneal shunts.
Topics: Adolescent; Azathioprine; C-Reactive Protein; Child; Female; Humans; Infant, Newborn; Infusions, Par | 2008 |
Radiographic findings of the National Cooperative Crohn's Disease Study.
Topics: Adult; Age Factors; Azathioprine; Colon; Crohn Disease; Duodenum; Female; Humans; Ileum; Intestinal | 1979 |
[Crohn's disease].
Topics: Appendicitis; Azathioprine; Cortisone; Crohn Disease; Diagnosis, Differential; Endoscopy; Female; Hu | 1977 |
Azathioprine in acute Crohn's disease.
Topics: Acute Disease; Azathioprine; Crohn Disease; Humans; Intestinal Obstruction; Male; Middle Aged | 1972 |
[Malabsorption syndrome and intestinal pseudoobstruction in primary vascular and heart amyloidosis].
Topics: Adult; Amyloidosis; Antibody Formation; Antigen-Antibody Complex; Azathioprine; Chloramphenicol; Cys | 1973 |
Crohn's disease in Transvaal blacks. A report of three cases with a review.
Topics: Acute Disease; Adult; Azathioprine; Black or African American; Black People; Crohn Disease; Diagnosi | 1974 |