Page last updated: 2024-10-23

azathioprine and Infectious Mononucleosis

azathioprine has been researched along with Infectious Mononucleosis in 5 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Infectious Mononucleosis: A common, acute infection usually caused by the Epstein-Barr virus (HERPESVIRUS 4, HUMAN). There is an increase in mononuclear white blood cells and other atypical lymphocytes, generalized lymphadenopathy, splenomegaly, and occasionally hepatomegaly with hepatitis.

Research Excerpts

ExcerptRelevanceReference
" We report two cases of atypical infectious mononucleosis in patients with inflammatory bowel disease under azathioprine therapy and review the available evidence on the most appropriate therapeutic approach in this subset of patients."8.84[Infectious mononucleosis in patients with inflammatory bowel disease under treatment with azathioprine]. ( Arévalo, JA; Bargalló, A; Cabré, E; Cabriada, JL; Carrión, S; Domènech, E; Gassull, MA; Mañosa, M, 2008)
"A 19 year old man with a history of Crohn's disease treated with azathioprine and prednisone, died after a primary infection with Epstein-Barr virus."5.29Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprine. ( Kluin, PM; Kluin-Nelemans, JC; Lamers, CB; Posthuma, EF; van der Sluys Veer, A; Westendorp, RG, 1995)
" We report two cases of atypical infectious mononucleosis in patients with inflammatory bowel disease under azathioprine therapy and review the available evidence on the most appropriate therapeutic approach in this subset of patients."4.84[Infectious mononucleosis in patients with inflammatory bowel disease under treatment with azathioprine]. ( Arévalo, JA; Bargalló, A; Cabré, E; Cabriada, JL; Carrión, S; Domènech, E; Gassull, MA; Mañosa, M, 2008)
"A 19 year old man with a history of Crohn's disease treated with azathioprine and prednisone, died after a primary infection with Epstein-Barr virus."1.29Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprine. ( Kluin, PM; Kluin-Nelemans, JC; Lamers, CB; Posthuma, EF; van der Sluys Veer, A; Westendorp, RG, 1995)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's1 (20.00)18.2507
2000's3 (60.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Villafruela Cives, M1
Moya Valverde, E1
de Manuel Moreno, J1
Sandoval Martínez, A1
Beceiro Pedreño, I1
Bargalló, A1
Carrión, S1
Domènech, E1
Arévalo, JA1
Mañosa, M1
Cabré, E1
Cabriada, JL1
Gassull, MA1
Posthuma, EF1
Westendorp, RG1
van der Sluys Veer, A1
Kluin-Nelemans, JC1
Kluin, PM1
Lamers, CB1
Garrido Serrano, A1
Pérez Martín, F1
Guerrero Igea, FJ1
Galbarro Muñoz, J1
Palomo Gil, S1
Lesesne, HR1
Fallon, HJ1

Reviews

3 reviews available for azathioprine and Infectious Mononucleosis

ArticleYear
[Infectious mononucleosis in patients with inflammatory bowel disease under treatment with azathioprine].
    Gastroenterologia y hepatologia, 2008, Volume: 31, Issue:5

    Topics: Adult; Azathioprine; Humans; Immunosuppressive Agents; Infectious Mononucleosis; Inflammatory Bowel

2008
[Fatal infectious mononucleosis during azathioprine treatment in Crohn's disease].
    Gastroenterologia y hepatologia, 2000, Volume: 23, Issue:1

    Topics: Adult; Azathioprine; Crohn Disease; Fatal Outcome; Gastrointestinal Hemorrhage; Humans; Immunosuppre

2000
Treatment of liver disease with corticosteroids.
    The Medical clinics of North America, 1973, Volume: 57, Issue:5

    Topics: Adrenal Cortex Hormones; Alcoholism; Azathioprine; Chemical and Drug Induced Liver Injury; Glucocort

1973

Other Studies

2 other studies available for azathioprine and Infectious Mononucleosis

ArticleYear
[Mononucleosis syndrome of multiple etiologies in a patient with Crohn's disease and azathioprine treatment].
    Revista espanola de enfermedades digestivas, 2009, Volume: 101, Issue:3

    Topics: Adolescent; Azathioprine; Crohn Disease; Female; Humans; Immunosuppressive Agents; Infectious Mononu

2009
Fatal infectious mononucleosis: a severe complication in the treatment of Crohn's disease with azathioprine.
    Gut, 1995, Volume: 36, Issue:2

    Topics: Adult; Azathioprine; Crohn Disease; Fatal Outcome; Humans; Immunosuppression Therapy; Infectious Mon

1995