Page last updated: 2024-10-23

azathioprine and Infections, Respiratory

azathioprine has been researched along with Infections, Respiratory in 22 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
"There are few data on the incidence of benign infections (upper respiratory tract infections, herpes lesions and viral warts) during exposure to azathioprine."7.75Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine. ( Beaugerie, L; Cosnes, J; Gendre, JP; Nion-Larmurier, I; Seksik, P; Sokol, H, 2009)
"There are few data on the incidence of benign infections (upper respiratory tract infections, herpes lesions and viral warts) during exposure to azathioprine."3.75Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine. ( Beaugerie, L; Cosnes, J; Gendre, JP; Nion-Larmurier, I; Seksik, P; Sokol, H, 2009)
" Prednisolone dosage was gradually tapered to 10 mg/d at 6 months, when cyclophosphamide was replaced by azathioprine (2 mg/kg/d p."2.69Treatment of membranous lupus nephritis with nephrotic syndrome by sequential immunosuppression. ( Chan, KW; Chan, TM; Hao, WK; Lai, KN; Li, FK; Lui, SL; Tang, S, 1999)
"If the vasculitis is secondary to an underlying disease, such as lymphoma, therapy should be directed at the primary disease."2.37Pulmonary vasculitis. ( Fauci, AS; Leavitt, RY, 1986)
"Bronchiectasis is characterized by abnormal, permanent and irreversible dilatation of the bronchi, usually responsible for daily symptoms and frequent respiratory complications."1.42Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study. ( Anglicheau, D; Babinet, F; Caillard, S; Colosio, C; Deslée, G; Dury, S; Essig, M; Etienne, I; Launois, C; Lebargy, F; Merieau, E; Perotin-Collard, JM; Rieu, P; Rivalan, J; Subra, JF; Thervet, E; Toubas, O, 2015)
" Four weeks after discontinuation of azathioprine, 1 treated cat again was given azathioprine at a lower dosage (1."1.28Systemic toxicosis associated with azathioprine administration in domestic cats. ( Altman, D; Beale, KM; Bolon, B; Clemmons, RR, 1992)
"In the azathioprine group, respiratory infections accounted for 24 of 60 (40%) infections."1.27Respiratory complications of cardiac transplantation. ( Drusin, R; Enson, Y; Reemtsma, K; Rose, EA; Schulman, LL; Smith, CR, 1988)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199016 (72.73)18.7374
1990's3 (13.64)18.2507
2000's2 (9.09)29.6817
2010's1 (4.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dury, S1
Colosio, C1
Etienne, I1
Anglicheau, D1
Merieau, E1
Caillard, S1
Rivalan, J1
Thervet, E1
Essig, M1
Babinet, F1
Subra, JF1
Toubas, O1
Rieu, P1
Launois, C1
Perotin-Collard, JM1
Lebargy, F1
Deslée, G1
Seksik, P1
Cosnes, J1
Sokol, H1
Nion-Larmurier, I1
Gendre, JP1
Beaugerie, L1
HILL, RB1
ROWLANDS, DT1
RIFKIND, D1
Date, H1
Yamane, M1
Toyooka, S1
Okazaki, M1
Oto, T1
Sano, Y1
Goto, K1
Drath, DB1
Kahan, BD1
Zuckermann, A1
Birsan, T1
Thaghavi, S1
Artemiou, O1
Kupilik, N1
Dekan, G1
Wolner, E1
Klepetko, W1
Chan, TM1
Li, FK1
Hao, WK1
Chan, KW1
Lui, SL1
Tang, S1
Lai, KN1
Schroeder, JS1
Rider, AK1
Stinson, EB3
Shumway, NE2
Beale, KM1
Altman, D1
Clemmons, RR1
Bolon, B1
Leavitt, RY1
Fauci, AS1
Schulman, LL1
Smith, CR1
Drusin, R1
Rose, EA1
Enson, Y1
Reemtsma, K1
McIntosh, RM1
Griswold, W1
Smith, FG1
Kaufman, DB1
Urizar, R1
Vernier, RL1
Mowbray, J1
Chebat, J1
Gluckman, JC1
Legrain, M1
Kuss, R1
Kondo, Y1
Cockrell, JV1
Kuwahara, O1
Hardy, JD1
Gordon, AM1
Briggs, JD1
Bell, PR1
Bieber, CP1
Griepp, RB1
Clark, DA1
Remington, JS1
Goldstein, HM1
Castellino, RA1
Wexler, L1
Walker, AN1
James, DG1
Bailey, AR1
Brunt, ME1
Hokkanen, E1
Green, D1
Hagberg, B1
Söderhjelm, L1
Lundmark, KM1
Verneholt, J1

Reviews

1 review available for azathioprine and Infections, Respiratory

ArticleYear
Pulmonary vasculitis.
    The American review of respiratory disease, 1986, Volume: 134, Issue:1

    Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cy

1986

Trials

2 trials available for azathioprine and Infections, Respiratory

ArticleYear
Mycophenolate mofetil in lung transplantation.
    Transplantation proceedings, 1998, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antilymphocyte Serum; Azathioprine; Communicable Diseases; Cyclosporine; Dr

1998
Treatment of membranous lupus nephritis with nephrotic syndrome by sequential immunosuppression.
    Lupus, 1999, Volume: 8, Issue:7

    Topics: Adult; Alopecia; Anti-Inflammatory Agents; Azathioprine; Cohort Studies; Cyclophosphamide; Drug Ther

1999

Other Studies

19 other studies available for azathioprine and Infections, Respiratory

ArticleYear
Bronchiectasis diagnosed after renal transplantation: a retrospective multicenter study.
    BMC pulmonary medicine, 2015, Nov-07, Volume: 15

    Topics: Adult; Agammaglobulinemia; Aged; Aged, 80 and over; Azathioprine; Bronchiectasis; Chronic Disease; C

2015
Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine.
    Alimentary pharmacology & therapeutics, 2009, May-15, Volume: 29, Issue:10

    Topics: Adolescent; Adult; Aged; Azathioprine; Cohort Studies; Female; Herpes Simplex; Humans; Immunosuppres

2009
INFECTIOUS PULMONARY DISEASE IN PATIENTS RECEIVING IMMUNOSUPPRESSIVE THERAPY FOR ORGAN TRANSPLANTATION.
    The New England journal of medicine, 1964, Nov-12, Volume: 271

    Topics: Animals; Antimetabolites; Aspergillosis; Azathioprine; Candidiasis; Cytomegalovirus Infections; Dact

1964
[Living-donor lobar lung transplantation for infectious lung diseases].
    Kyobu geka. The Japanese journal of thoracic surgery, 2007, Volume: 60, Issue:11

    Topics: Adult; Azathioprine; Cardiopulmonary Bypass; Cyclosporine; Female; Graft Rejection; Humans; Living D

2007
Phagocytic cell function in response to immunosuppressive therapy.
    Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:2

    Topics: Animals; Azathioprine; Chemotaxis, Leukocyte; Cyclosporins; Humans; Immunosuppressive Agents; Kidney

1984
Cardiac transplantation: review of seven years' experience.
    Transplantation proceedings, 1976, Volume: 8, Issue:1

    Topics: Azathioprine; Coronary Disease; Graft Rejection; Heart Transplantation; Immunosuppression Therapy; P

1976
Systemic toxicosis associated with azathioprine administration in domestic cats.
    American journal of veterinary research, 1992, Volume: 53, Issue:7

    Topics: Animals; Azathioprine; Bone Marrow; Cat Diseases; Cats; Female; Leukocyte Count; Male; Neutropenia;

1992
Respiratory complications of cardiac transplantation.
    The American journal of the medical sciences, 1988, Volume: 296, Issue:1

    Topics: Adult; Azathioprine; Cyclosporins; Female; Follow-Up Studies; Heart Transplantation; Humans; Male; P

1988
Azathioprine in glomerulonephritis. A long-term study.
    Lancet (London, England), 1972, May-20, Volume: 1, Issue:7760

    Topics: Adolescent; Azathioprine; Basement Membrane; Child; Chronic Disease; Follow-Up Studies; Glomerular F

1972
Platelet thrombi in rejection episodes.
    Proceedings of the Royal Society of Medicine, 1969, Volume: 62, Issue:6

    Topics: Antibody Formation; Azathioprine; Blood Coagulation; Blood Platelets; Chromium Isotopes; Dactinomyci

1969
[Infectious pulmonary complications observed after renal transplantation (analysis of 104 cases)].
    Annales de medecine interne, 1973, Volume: 124, Issue:2

    Topics: Azathioprine; Bacterial Infections; Immunosuppressive Agents; Kidney Transplantation; Lung Diseases;

1973
Histopathology of one-stage bilateral lung allografts.
    Annals of surgery, 1974, Volume: 180, Issue:5

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Bronchi; Dogs; Graft Rejection; Immunosuppression Thera

1974
The nitroblue tetrazolium (NBT) test in renal transplantation.
    Journal of clinical pathology, 1974, Volume: 27, Issue:9

    Topics: Abscess; Adult; Azathioprine; Diagnosis, Differential; Escherichia coli; Female; Glomerulonephritis;

1974
Infectious complications after cardiac transplantation in man.
    Annals of internal medicine, 1971, Volume: 74, Issue:1

    Topics: Adult; Amphotericin B; Antilymphocyte Serum; Azathioprine; Dactinomycin; Female; Heart Transplantati

1971
Roentgenologic aspects of cardiac transplantation. Postoperative pulmonary infections.
    The American journal of roentgenology, radium therapy, and nuclear medicine, 1971, Volume: 111, Issue:3

    Topics: Adult; Azathioprine; Biopsy; Cardiomyopathies; Coronary Disease; Female; Heart Transplantation; Huma

1971
Fresh drugs for old problems.
    The British journal of clinical practice, 1971, Volume: 25, Issue:2

    Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Azathioprine; Cephalosporins; Humans; Liver Abscess,

1971
Myasthenia gravis. A clinical analysis of the total material from Finland with special reference to endocrinological and neurological disorders.
    Annals of clinical research, 1969, Volume: 1, Issue:2

    Topics: Age Factors; Ambenonium Chloride; Azathioprine; Cortisone; Diabetes Complications; Disability Evalua

1969
Suppression of an antibody to factor VIII by a combination of factor VIII and cyclophosphamide.
    Blood, 1971, Volume: 37, Issue:4

    Topics: Antibodies; Antigen-Antibody Reactions; Antigens; Azathioprine; Blood Coagulation Disorders; Blood C

1971
[Polyradiculoneuritis--a review in connection with a therapeutic experiment].
    Lakartidningen, 1971, Feb-24, Volume: 68, Issue:9

    Topics: Adolescent; Autoimmune Diseases; Azathioprine; Child; Female; Humans; Male; Polyradiculopathy; Predn

1971