azathioprine has been researched along with Immunoglobulin G4-Related Disease in 12 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Immunoglobulin G4-Related Disease: A spectrum of systemic autoimmune diseases in which IMMUNOGLOBULIN G4 plays a pathophysiologic role. It can affect multiple organs in highly variable presentations, characterized by inflammatory lesions composed of IgG4-positive PLASMA CELLS, further infiltrated by T helper cells (T-LYMPHOCYTES, HELPER-INDUCER) when linked to progressive FIBROSIS and eventual organ damage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine was used as a maintenance treatment." | 2.66 | Recurrent myelitis and asymptomatic hypophysitis in IgG4-related disease: case-based review. ( Anagnostouli, M; Andreadou, E; Boutzios, G; Evangelopoulos, ME; Fragoulis, GE; Kilidireas, C; Koutsis, G; Stefanis, L; Toulas, P; Tzanetakos, D; Tzartos, J; Vakrakou, AG; Velonakis, G, 2020) |
| "Azathioprine has previously been used in systemic cases of IgG4-RD but has not been reported for isolated esophageal disease." | 1.72 | Isolated esophageal IgG4-related disease presenting with progressive dysphagia and weight loss in a middle-aged man. ( Fehily, S; Holmes, JA; Lust, M; McKelvie, P; Miller, A; Poole, H, 2022) |
| "Patients with IgG4-related disease (IgG4-RD) typically respond well to initial glucocorticoid therapy, but always relapse with tapered or maintenance dosage of steroid." | 1.56 | Relapse predictors and serologically unstable condition of IgG4-related disease: a large Chinese cohort. ( Chen, D; Gao, J; Li, ZG; Liu, Y; Shen, D; Wang, K; Wang, Y; Wang, Z; Xia, C; Yang, F; Yu, G; Zeng, Q; Zhang, S; Zhu, L, 2020) |
| "We prospectively enrolled 215 newly diagnosed patients with IgG4-RD, who were initially treated with glucocorticoid (GC) alone or in combination with immunosuppressive agents (IM), and had at least 6 months of follow up." | 1.48 | Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4-related disease: a prospective study of 215 patients. ( Fei, Y; Feng, R; Lai, Y; Peng, L; Wang, L; Wang, M; Zeng, X; Zhang, F; Zhang, P; Zhang, W; Zhang, X; Zhao, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 8 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Poole, H | 1 |
| Fehily, S | 1 |
| McKelvie, P | 1 |
| Miller, A | 1 |
| Lust, M | 1 |
| Holmes, JA | 1 |
| Omar, D | 1 |
| Chen, Y | 1 |
| Cong, Y | 1 |
| Dong, L | 1 |
| Vakrakou, AG | 1 |
| Evangelopoulos, ME | 1 |
| Boutzios, G | 1 |
| Tzanetakos, D | 1 |
| Tzartos, J | 1 |
| Velonakis, G | 1 |
| Toulas, P | 1 |
| Anagnostouli, M | 1 |
| Andreadou, E | 1 |
| Koutsis, G | 1 |
| Stefanis, L | 1 |
| Fragoulis, GE | 1 |
| Kilidireas, C | 1 |
| Liu, Y | 1 |
| Zeng, Q | 1 |
| Zhu, L | 1 |
| Gao, J | 1 |
| Wang, Z | 2 |
| Yang, F | 1 |
| Wang, K | 1 |
| Chen, D | 1 |
| Xia, C | 1 |
| Zhang, S | 1 |
| Wang, Y | 1 |
| Shen, D | 1 |
| Yu, G | 1 |
| Li, ZG | 1 |
| Kastin, D | 1 |
| Siegel, M | 1 |
| Anderson, R | 1 |
| Aronsohn, A | 1 |
| Yamamoto, M | 1 |
| Noda, S | 1 |
| Honda, S | 1 |
| Hirota, Y | 1 |
| Ito, T | 1 |
| Hasegawa, H | 1 |
| Kimura, N | 1 |
| Matsuo, Y | 1 |
| Iwai, H | 1 |
| Kohsaka, H | 1 |
| Yasuda, S | 1 |
| Pastor Rueda, JM | 1 |
| Alessandro, L | 1 |
| Calandri, IL | 1 |
| Cammarota, Á | 1 |
| Fernández-Codina, A | 1 |
| Pinilla, B | 1 |
| Pinal-Fernández, I | 1 |
| López, C | 1 |
| Fraile-Rodríguez, G | 1 |
| Fonseca-Aizpuru, E | 1 |
| Carballo, I | 1 |
| Brito-Zerón, P | 1 |
| Feijóo-Massó, C | 1 |
| López-Dupla, M | 1 |
| Cid, MC | 1 |
| Martínez-Valle, F | 1 |
| Wang, L | 1 |
| Zhang, P | 1 |
| Wang, M | 1 |
| Feng, R | 1 |
| Lai, Y | 1 |
| Peng, L | 1 |
| Fei, Y | 1 |
| Zhang, X | 1 |
| Zhao, Y | 1 |
| Zeng, X | 1 |
| Zhang, F | 1 |
| Zhang, W | 1 |
| Soriano Rios, A | 1 |
| Paredes, H | 1 |
| Hernández-Calleros, J | 1 |
| Uscanga-Domínguez, L | 1 |
| Peláez-Luna, M | 1 |
| Ron, R | 1 |
| Ruz-Caracuel, I | 1 |
| García, E | 1 |
| Montes-Ramírez, ML | 1 |
2 reviews available for azathioprine and Immunoglobulin G4-Related Disease
| Article | Year |
|---|---|
Glucocorticoids and steroid sparing medications monotherapies or in combination for IgG4-RD: a systematic review and network meta-analysis.
Topics: Antirheumatic Agents; Azathioprine; Cyclophosphamide; Cyclosporine; Drug Therapy, Combination; Gluco | 2020 |
Recurrent myelitis and asymptomatic hypophysitis in IgG4-related disease: case-based review.
Topics: Adolescent; Asymptomatic Diseases; Autoimmune Hypophysitis; Azathioprine; Cervical Vertebrae; Female | 2020 |
10 other studies available for azathioprine and Immunoglobulin G4-Related Disease
| Article | Year |
|---|---|
Isolated esophageal IgG4-related disease presenting with progressive dysphagia and weight loss in a middle-aged man.
Topics: Azathioprine; Deglutition Disorders; Humans; Immunoglobulin G4-Related Disease; Male; Middle Aged; W | 2022 |
Relapse predictors and serologically unstable condition of IgG4-related disease: a large Chinese cohort.
Topics: Adult; Age Factors; Azathioprine; Biomarkers; Cyclophosphamide; Drug Therapy, Combination; Female; G | 2020 |
IgG 4 Autoimmune Hepatitis Presenting as Idiopathic Hypereosinophilia Syndrome.
Topics: Azathioprine; Female; Glucocorticoids; Hepatitis, Autoimmune; Humans; Hypereosinophilic Syndrome; Im | 2021 |
B cell targeted therapy for immunoglobulin G4-related disease.
Topics: Azathioprine; Humans; Immunoglobulin G4-Related Disease; Immunosuppressive Agents; Memory B Cells; R | 2021 |
Azathioprine Monotherapy for the Cases of Immunoglobulin G4-Related Disease With Contraindications to Glucocorticoids.
Topics: Azathioprine; Contraindications; Glucocorticoids; Humans; Immunoglobulin G4-Related Disease; Immunos | 2021 |
Neurological symptoms as the initial manifestation of IgG4-related disease.
Topics: Adrenal Cortex Hormones; Age Factors; Aged; Azathioprine; Cyclophosphamide; Headache; Humans; Immuno | 2020 |
Treatment and outcomes in patients with IgG4-related disease using the IgG4 responder index.
Topics: Adult; Aged; Azathioprine; Biomarkers; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Female; | 2018 |
Failure of remission induction by glucocorticoids alone or in combination with immunosuppressive agents in IgG4-related disease: a prospective study of 215 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Child; Cohort Studies; Cyclophosphamide; C | 2018 |
Retroperitoneal fibrosis. Steroid treatment response seems to depend on its association to IgG4 related disease.
Topics: Adult; Age of Onset; Aged; Autoimmune Diseases; Azathioprine; Female; Follow-Up Studies; Humans; Imm | 2019 |
IgG4-related disease in a patient with HIV infection.
Topics: Azathioprine; Dyspnea; Glucocorticoids; HIV Infections; Humans; Immunoglobulin G; Immunoglobulin G4- | 2019 |