azathioprine has been researched along with Immune System Diseases in 16 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Immune System Diseases: Disorders caused by abnormal or absent immunologic mechanisms, whether humoral, cell-mediated, or both.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine (AZA) is characterized by high interindividual differences in bioavailability and metabolization." | 1.31 | Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine. ( Decaux, G; Desager, JP; Horsmans, Y; Prospert, F, 2000) |
| "Prednisone was administered to 134 patients (90 per cent) in whom a peak platelet count occurred at a median of eight days, at which time four distinct patterns of response became evident: 20 patients (15 per cent) achieved complete remission with platelet counts greater than 200 X 10(9)/I, and of these 13 relapsed; 46 (34 per cent) had incomplete remission with platelet counts between 100 and 200 X 10(9)/I, and of these 38 relapsed; 22 (17 per cent) had a partial remission with platelet counts between 50 and 100 X 10(9)/I, and 14 have relapsed; the remaining 46 (34 per cent) failed to respond to prednisone." | 1.27 | Results of treatment in immune thrombocytopenia. ( Dent, DM; Jacobs, P; Wood, L, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (75.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Katz, P | 1 |
| Niaudet, P | 1 |
| Cohen, JA | 1 |
| Raps, EC | 1 |
| Pallis, M | 1 |
| Lim, KL | 1 |
| Gardner-Medwin, JM | 1 |
| Robins, RA | 1 |
| Powell, RJ | 1 |
| Miller, E | 1 |
| Decaux, G | 1 |
| Prospert, F | 1 |
| Horsmans, Y | 1 |
| Desager, JP | 1 |
| Oshrain, HI | 1 |
| Mender, S | 1 |
| Mandel, ID | 1 |
| Baenkler, VH | 1 |
| Bach, JF | 1 |
| Hallauer, W | 1 |
| Schirmeister, J | 1 |
| Keller, P | 1 |
| Krieger, G | 1 |
| Schirrmeister, H | 1 |
| Tilson, HH | 1 |
| Beale, KM | 1 |
| Jacobs, P | 1 |
| Wood, L | 1 |
| Dent, DM | 1 |
| Van Scoik, KG | 1 |
| Johnson, CA | 1 |
| Porter, WR | 1 |
| Kaufman, DB | 1 |
| McIntosh, RM | 1 |
| Videbaek, A | 1 |
4 reviews available for azathioprine and Immune System Diseases
| Article | Year |
|---|---|
Critical neurologic illness in the immunocompromised patient.
Topics: Acquired Immunodeficiency Syndrome; Anti-Inflammatory Agents; Antibody Formation; Azathioprine; Brai | 1995 |
The use of cytotoxic agents in the treatment of immune-mediated diseases of dogs and cats.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Azathioprine; Cat Disea | 1997 |
The pharmacology and metabolism of the thiopurine drugs 6-mercaptopurine and azathioprine.
Topics: Animals; Azathioprine; Biotransformation; DNA; DNA Replication; Humans; Immune System Diseases; Merc | 1985 |
[Immunosuppressive therapy. A survey concerning rationale, risks, indications and contraindications].
Topics: Adolescent; Adult; Azathioprine; Drug Therapy, Combination; Female; Humans; Immune System Diseases; | 1973 |
1 trial available for azathioprine and Immune System Diseases
| Article | Year |
|---|---|
Correlation between CD29 density on CD8+ lymphocytes and serum IgG in systemic lupus erythematosus.
Topics: Antigens, CD; Azathioprine; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cohort Studies; | 1997 |
11 other studies available for azathioprine and Immune System Diseases
| Article | Year |
|---|---|
Therapy for immunologic disease. New ways of using old drugs.
Topics: Adrenal Cortex Hormones; Azathioprine; Cyclophosphamide; Cytotoxicity, Immunologic; Drug Administrat | 1983 |
[Immunosuppressive agents].
Topics: Alkylating Agents; Antilymphocyte Serum; Azathioprine; Humans; Immune System Diseases; Immunosuppres | 1980 |
Relationship between red cell mean corpuscular volume and 6-thioguanine nucleotides in patients treated with azathioprine.
Topics: Adult; Azathioprine; Biological Availability; Churg-Strauss Syndrome; Erythrocyte Indices; Erythrocy | 2000 |
Periodontal status of patients with reduced immunocapacity.
Topics: Adult; Azathioprine; Dental Plaque; Gingivitis; Humans; Immune System Diseases; Immunosuppressive Ag | 1979 |
[Immunologic diseases--conclusion 10. Immunosuppression, recommendations for ambulatory treatment and supervision].
Topics: Ambulatory Care; Azathioprine; Cyclophosphamide; Female; Humans; Immune System Diseases; Immunosuppr | 1977 |
The mode of action of immunosuppressive agents.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents; Antilymphocyte Serum; Azathioprine; Cell Survi | 1975 |
[Collagen disease with pure red cell anemia and perimembraneous glomerulonephritis (author's transl)].
Topics: Adult; Anemia; Anemia, Hemolytic; Antibodies, Antinuclear; Azathioprine; Bone Marrow; Bone Marrow Ce | 1976 |
Pharmacoepidemiology: the industry's perspective.
Topics: Arthritis, Rheumatoid; Azathioprine; Decision Making; Drug Industry; Epidemiology; Humans; Immune Sy | 1988 |
Azathioprine for treatment of immune-mediated diseases of dogs and cats.
Topics: Animals; Azathioprine; Cat Diseases; Cats; Dog Diseases; Dogs; Immune System Diseases | 1988 |
Results of treatment in immune thrombocytopenia.
Topics: Adolescent; Adult; Aged; Azathioprine; Cyclophosphamide; Female; Humans; Immune System Diseases; Mal | 1986 |
The effects of azathioprine on experimentally induced immune complex renal disease in rabbits.
Topics: Animals; Azathioprine; Blood Protein Electrophoresis; Cattle; Creatinine; Fluorescent Antibody Techn | 1972 |