Page last updated: 2024-10-23

azathioprine and Ileitis

azathioprine has been researched along with Ileitis in 16 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Ileitis: Inflammation of any segment of the ILEUM and the ILEOCECAL VALVE.

Research Excerpts

ExcerptRelevanceReference
"The study included 20 consecutive patients with Crohn's colitis or ileocolitis in clinical remission while taking azathioprine for at least 9 months and no corticosteroids for at least 3 months who had had an ileocolonoscopy less than 1 year before the start of azathioprine."9.09Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. ( D'Haens, G; Geboes, K; Rutgeerts, P, 1999)
"Of the 19 patients treated with azathioprine for recurrent ileitis, 15 could be reevaluated by endoscopy or radiological examination."7.69Healing of severe recurrent ileitis with azathioprine therapy in patients with Crohn's disease. ( D'Haens, G; Geboes, K; Penninckx, F; Ponette, E; Rutgeerts, P, 1997)
"The study included 20 consecutive patients with Crohn's colitis or ileocolitis in clinical remission while taking azathioprine for at least 9 months and no corticosteroids for at least 3 months who had had an ileocolonoscopy less than 1 year before the start of azathioprine."5.09Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine. ( D'Haens, G; Geboes, K; Rutgeerts, P, 1999)
"Of the 19 patients treated with azathioprine for recurrent ileitis, 15 could be reevaluated by endoscopy or radiological examination."3.69Healing of severe recurrent ileitis with azathioprine therapy in patients with Crohn's disease. ( D'Haens, G; Geboes, K; Penninckx, F; Ponette, E; Rutgeerts, P, 1997)
"It is important to distinguish between ulcerative colitis and Crohn's colitis because response to treatment and prognosis are different."2.35Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis. ( Ament, ME, 1975)
"To ascertain whether patients with Crohn's disease treated with azathioprine maintained bone mineral mass better than patients treated with steroids alone."1.30Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine. ( Ahrén, B; Bartosik, J; Bengtsson, M; Florén, CH; Obrant, K, 1998)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's5 (31.25)18.2507
2000's1 (6.25)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Booth, AT1
Forster, E1
Curran, T1
George, V1
Yu, LF1
Zhong, J1
Cheng, SD1
Tang, YH1
Miao, F1
Donghi, D1
Mainetti, C1
Higgins, PD1
Le Guenno, G1
Galicier, L1
Uro-Coste, E1
Petitcolin, V1
Rieu, V1
Ruivard, M1
Weinkove, R1
Dickson, M1
Eliadou, E1
Stace, NH1
Goossens, L1
Ferguson, P1
Kennedy, ED1
Urbach, DR1
Krahn, MD1
Steinhart, AH1
Cohen, Z1
McLeod, RS1
Kirsner, JB1
Deutsch, S1
Hanauer, SB1
Hallak, A1
Baratz, M1
Santo, M1
Halpern, Z1
Rabau, M1
Werbin, N1
Gilat, T1
D'Haens, G2
Geboes, K2
Ponette, E1
Penninckx, F1
Rutgeerts, P2
Enns, R1
Lay, T1
Bridges, R1
Florén, CH1
Ahrén, B1
Bengtsson, M1
Bartosik, J1
Obrant, K1
Ament, ME1
Williams, JA1
Brown, CH1
Achkar, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Risk-stratified Randomized Controlled Trial in Paediatric Crohn Disease:Methotrexate vs Azathioprine or Adalimumab for Maintaining Remission in Patients at Low or High Risk for Aggressive Disease Course, respectively-a Treatment Strategy[NCT02852694]Phase 4312 participants (Anticipated)Interventional2017-02-28Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for azathioprine and Ileitis

ArticleYear
Inflammatory disease of the colon: ulcerative colitis and Crohn's colitis.
    The Journal of pediatrics, 1975, Volume: 86, Issue:3

    Topics: Adrenal Cortex Hormones; Adult; Anus Diseases; Arthritis; Azathioprine; Child, Preschool; Colectomy;

1975
The place of surgery in Crohn's disease.
    Gut, 1971, Volume: 12, Issue:9

    Topics: Abscess; Acute Disease; Anemia; Appendectomy; Azathioprine; Colectomy; Colonic Diseases; Crohn Disea

1971

Trials

2 trials available for azathioprine and Ileitis

ArticleYear
Low-dose azathioprine effectively improves mucosal healing in Chinese patients with small bowel Crohn's disease.
    Journal of digestive diseases, 2014, Volume: 15, Issue:4

    Topics: Adolescent; Adult; Azathioprine; Crohn Disease; Double-Balloon Enteroscopy; Drug Administration Sche

2014
Endoscopic and histologic healing of Crohn's (ileo-) colitis with azathioprine.
    Gastrointestinal endoscopy, 1999, Volume: 50, Issue:5

    Topics: Adult; Azathioprine; Biopsy; Colitis; Colon; Crohn Disease; Drug Therapy, Combination; Endoscopy, Ga

1999

Other Studies

12 other studies available for azathioprine and Ileitis

ArticleYear
Gastrocolic Fistula Involving the Pancreas in a Patient With Crohn's Disease.
    The American journal of gastroenterology, 2019, Volume: 114, Issue:11

    Topics: Adalimumab; Azathioprine; Budesonide; Colectomy; Colitis; Crohn Disease; Gastric Fistula; Humans; Il

2019
Infliximab for the treatment of refractory Adamantiades-Behçet disease with articular, intestinal, cerebral and ocular involvement.
    Dermatology (Basel, Switzerland), 2010, Volume: 220, Issue:3

    Topics: Adolescent; Antibodies, Monoclonal; Arthritis; Aspirin; Azathioprine; Behcet Syndrome; Chronic Disea

2010
Who wants to take a thiopurine holiday?
    The American journal of gastroenterology, 2011, Volume: 106, Issue:4

    Topics: Adult; Azathioprine; Biomarkers; Blood Sedimentation; C-Reactive Protein; Crohn Disease; Diagnostic

2011
Successful treatment with azathioprine of relapsing Rosai-Dorfman disease of the central nervous system.
    Journal of neurosurgery, 2012, Volume: 117, Issue:3

    Topics: Azathioprine; Central Nervous System Diseases; Comorbidity; Crohn Disease; Follow-Up Studies; Histio

2012
Fever and pancytopenia in a patient with Crohn's disease.
    Gut, 2013, Volume: 62, Issue:9

    Topics: Angiography; Antiviral Agents; Azathioprine; Cecum; Crohn Disease; Digestive System Surgical Procedu

2013
Azathioprine or ileocolic resection for steroid-dependent terminal ileal Crohn's disease? A Markov analysis.
    Diseases of the colon and rectum, 2004, Volume: 47, Issue:12

    Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Cohort Studies; Colectomy; Combined Modality Therapy;

2004
Selected individual therapeutic problems in inflammatory bowel disease.
    The American journal of gastroenterology, 1984, Volume: 79, Issue:5

    Topics: Adult; Azathioprine; Campylobacter Infections; Clostridium Infections; Colectomy; Colitis, Ulcerativ

1984
Ileitis after colectomy for ulcerative colitis or carcinoma.
    Gut, 1994, Volume: 35, Issue:3

    Topics: Adult; Aged; Aminosalicylic Acids; Azathioprine; Colectomy; Colitis, Ulcerative; Colonic Neoplasms;

1994
Healing of severe recurrent ileitis with azathioprine therapy in patients with Crohn's disease.
    Gastroenterology, 1997, Volume: 112, Issue:5

    Topics: Adult; Azathioprine; Crohn Disease; Endoscopy; Female; Humans; Ileitis; Ileum; Immunosuppressive Age

1997
Use of azathioprine for nongranulomatous ulcerative jejunoileitis.
    Canadian journal of gastroenterology = Journal canadien de gastroenterologie, 1997, Volume: 11, Issue:6

    Topics: Azathioprine; Enteritis; Female; Humans; Ileitis; Immunosuppressive Agents; Jejunal Diseases; Middle

1997
Bone mineral density in patients with Crohn's disease during long-term treatment with azathioprine.
    Journal of internal medicine, 1998, Volume: 243, Issue:2

    Topics: Absorptiometry, Photon; Adult; Aged; Azathioprine; Bone Density; Colitis; Crohn Disease; Female; Hum

1998
Azathioprine therapy for inflammatory bowel disease. A preliminary report.
    The American journal of gastroenterology, 1970, Volume: 54, Issue:4

    Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Azathioprine; Chronic Disease; Colitis, Ulcerative;

1970