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azathioprine and Hyperuricemia

azathioprine has been researched along with Hyperuricemia in 4 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Hyperuricemia: Excessive URIC ACID or urate in blood as defined by its solubility in plasma at 37 degrees C; greater than 0.42mmol per liter (7.0mg/dL) in men or 0.36mmol per liter (6.0mg/dL) in women. This condition is caused by overproduction of uric acid or impaired renal clearance. Hyperuricemia can be acquired, drug-induced or genetically determined (LESCH-NYHAN SYNDROME). It is associated with HYPERTENSION and GOUT.

Research Excerpts

ExcerptRelevanceReference
" We describe a patient suffering from pancytopenia following a combination therapy of azathioprine and allopurinol because of lupus erythematodes and diabetic nephropathy with hyperuricemia."3.72[Panzytopenia from combination therapy with azathioprin and allopurinol]. ( Seidel, W, 2004)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Perez-Ruiz, F1
Gomez-Ullate, P1
Amenabar, JJ1
Zarraga, S1
Calabozo, M1
Herrero-Beites, AM1
Nolla, JM1
Marcén, R1
Gallego, N1
Orofino, L1
Sabater, J1
Pascual, J1
Teruel, JL1
Liaño, F1
Ortuño, J1
Seidel, W1
Edwards, NL1

Other Studies

4 other studies available for azathioprine and Hyperuricemia

ArticleYear
Long-term efficacy of hyperuricaemia treatment in renal transplant patients.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2003, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Aged; Allopurinol; Antimetabolites; Azathioprine; Child; Cohort Studies; Female;

2003
Influence of cyclosporin A (CyA) on renal handling of urate.
    Transplant international : official journal of the European Society for Organ Transplantation, 1992, Volume: 5 Suppl 1

    Topics: Adult; Azathioprine; Cyclosporine; Diuretics; Drug Therapy, Combination; Female; Follow-Up Studies;

1992
[Panzytopenia from combination therapy with azathioprin and allopurinol].
    Zeitschrift fur Rheumatologie, 2004, Volume: 63, Issue:5

    Topics: Aged; Allopurinol; Antirheumatic Agents; Autoantibodies; Azathioprine; Blood Cell Count; Diabetes Me

2004
Case 9: initiation of urate-lowering therapy for advanced gout complicated by chronic renal insufficiency.
    The American journal of medicine, 2006, Volume: 119, Issue:11 Suppl 1

    Topics: Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; Contraindications; Drug Interact

2006