azathioprine has been researched along with Hypertension, Pulmonary in 18 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report a case of a woman with pulmonary hypertension secondary to rheumatoid arthritis, whose treatment with azathioprine resulted in normalization of pulmonary artery pressure and resolution of clinical symptoms." | 4.83 | Isolated pulmonary hypertension secondary to rheumatoid arthritis. ( Appenzeller, S; Bertolo, MB; Castro, GW; Costallat, LT, 2006) |
| " According to the possibility of either idiopathic pulmonary fibrosis or chronic hypersensitivity pneumonitis, treatment included prednisolone, azathioprine, acetylcysteine and avoidance of contact with the parakeet, but there was an unfavorable response and the patient was subsequently referred for lung transplant." | 3.79 | Clinical case: Differential diagnosis of idiopathic pulmonary fibrosis. ( Alfaro, TM; Cordeiro, CR; Freitas, S, 2013) |
| "Fatigue is a frequent symptom of patients with sarcoidosis." | 1.40 | Factors associated with fatigue in sarcoidosis. ( Bosse-Henck, A; Brähler, E; Fleischer, M; Hinz, A; Wirtz, H, 2014) |
| "Combined idiopathic pulmonary fibrosis (IPF) with pulmonary emphysema (CPFE) is a syndrome with a characteristic presentation of upper lobe emphysema and lower lobe fibrosis." | 1.39 | Clinical case: Combined pulmonary fibrosis and emphysema with pulmonary hypertension--clinical management. ( Cottin, V, 2013) |
| "Pulmonary hypertension is common in advanced fibrotic IIP, and has a negative impact on survival." | 1.36 | Fibrotic idiopathic interstitial pneumonias: mortality is linked to a decline in gas transfer. ( Blumenthal, JP; Bresser, P; Jonkers, RE; Peek, N; Peelen, L; Prijs, M; van Steenwijk, RP; Wells, AU, 2010) |
| "Primary systemic sclerosis (PSS) is such a disease characterised by multi-organ fibrosis." | 1.35 | Graves' disease associated with primary systemic sclerosis. ( Wimmersberger, Y; Zuercher, D, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (27.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 7 (38.89) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Fanouriakis, A | 1 |
| Tziolos, N | 1 |
| Bertsias, G | 1 |
| Boumpas, DT | 1 |
| Cordeiro, CR | 1 |
| Alfaro, TM | 1 |
| Freitas, S | 1 |
| Cottin, V | 1 |
| Fleischer, M | 1 |
| Hinz, A | 1 |
| Brähler, E | 1 |
| Wirtz, H | 1 |
| Bosse-Henck, A | 1 |
| Wimmersberger, Y | 1 |
| Zuercher, D | 1 |
| Peelen, L | 1 |
| Wells, AU | 1 |
| Prijs, M | 1 |
| Blumenthal, JP | 1 |
| van Steenwijk, RP | 1 |
| Jonkers, RE | 1 |
| Peek, N | 1 |
| Bresser, P | 1 |
| Naniwa, T | 1 |
| Takeda, Y | 1 |
| Mukerjee, D | 1 |
| Kingdon, E | 1 |
| Vanderpump, M | 1 |
| Coghlan, JG | 1 |
| Sarahrudi, K | 1 |
| Estenne, M | 1 |
| Corris, P | 1 |
| Niedermayer, J | 1 |
| Knoop, C | 1 |
| Glanville, A | 1 |
| Chaparro, C | 1 |
| Verleden, G | 1 |
| Gerbase, MW | 1 |
| Venuta, F | 1 |
| Böttcher, H | 1 |
| Aubert, JD | 1 |
| Levvey, B | 1 |
| Reichenspurner, H | 1 |
| Auterith, A | 1 |
| Klepetko, W | 1 |
| Nagashima, T | 1 |
| Masuyama, J | 1 |
| Okubo, H | 1 |
| Minota, S | 1 |
| Nakazawa, T | 1 |
| Kumagai, S | 1 |
| Kogata, Y | 1 |
| Castro, GW | 1 |
| Appenzeller, S | 1 |
| Bertolo, MB | 1 |
| Costallat, LT | 1 |
| Jamieson, SW | 2 |
| Baldwin, J | 1 |
| Stinson, EB | 2 |
| Reitz, BA | 1 |
| Oyer, PE | 2 |
| Hunt, S | 2 |
| Billingham, M | 2 |
| Theodore, J | 2 |
| Modry, D | 1 |
| Bieber, CP | 1 |
| Dawkins, K | 1 |
| Shumway, NE | 2 |
| Ribeiro, JM | 1 |
| Lucas, M | 1 |
| Victorino, RM | 1 |
| Daoud, FS | 1 |
| Reeves, JT | 1 |
| Kelly, DB | 1 |
| Skwarski, K | 1 |
| Zieliński, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Optimization of Glucocorticoid Taper Strategies for Maintenance Therapy of Systemic Lupus Erythematosus Associated Immune Thrombocytopenia (SLE-ITP)[NCT05506033] | 120 participants (Anticipated) | Interventional | 2022-08-15 | Enrolling by invitation | |||
| Randomized, Open-label, Multi-Center Study Comparing Tacrolimus With Cyclosporin, Both Arms in Combination With Mycophenolate Mofetil and Corticosteroids for Prevention of Bronchiolitis Obliterans Syndrome in Lung Transplant Patients[NCT01429844] | Phase 3 | 274 participants (Actual) | Interventional | 2001-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Update οn the diagnosis and management of systemic lupus erythematosus.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Monoclonal, Humanized; Autoantibodies; Azathioprine; Calc | 2021 |
[Pharmacotherapy of SLE].
Topics: Adrenal Cortex Hormones; Anemia, Hemolytic; Anti-Inflammatory Agents, Non-Steroidal; Azathioprine; C | 2005 |
Isolated pulmonary hypertension secondary to rheumatoid arthritis.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Blood Pressure; Female; Humans; Hy | 2006 |
15 other studies available for azathioprine and Hypertension, Pulmonary
| Article | Year |
|---|---|
Clinical case: Differential diagnosis of idiopathic pulmonary fibrosis.
Topics: Acetylcysteine; Alveolitis, Extrinsic Allergic; Azathioprine; Diagnosis, Differential; Disease Manag | 2013 |
Clinical case: Combined pulmonary fibrosis and emphysema with pulmonary hypertension--clinical management.
Topics: Acetylcysteine; Azathioprine; Disease Management; Humans; Hypertension, Pulmonary; Lung; Male; Middl | 2013 |
Factors associated with fatigue in sarcoidosis.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Cohort Studies; Fatigue; Female; Germany; Humans; Hyp | 2014 |
Graves' disease associated with primary systemic sclerosis.
Topics: Azathioprine; Bosentan; Cyclophosphamide; Drug Therapy, Combination; Female; Glucocorticoids; Graves | 2009 |
Fibrotic idiopathic interstitial pneumonias: mortality is linked to a decline in gas transfer.
Topics: Aged; Anti-Inflammatory Agents; Azathioprine; Blood Gas Analysis; Cyclophosphamide; Disease-Free Sur | 2010 |
Long-term remission of pulmonary veno-occlusive disease associated with primary Sjögren's syndrome following immunosuppressive therapy.
Topics: Azathioprine; Female; Heart Failure; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Pred | 2011 |
Pathophysiological insights from a case of reversible pulmonary arterial hypertension.
Topics: Azathioprine; Echocardiography; Humans; Hypertension, Pulmonary; Immunosuppressive Agents; Male; Mid | 2003 |
International experience with conversion from cyclosporine to tacrolimus for acute and chronic lung allograft rejection.
Topics: Acute Disease; Adult; Australia; Azathioprine; Bronchiolitis Obliterans; Canada; Chronic Disease; Cy | 2004 |
Marked dilatation of pulmonary arteries in mixed connective tissue disease.
Topics: Activities of Daily Living; Azathioprine; Blood Pressure; Digoxin; Dilatation, Pathologic; Drug Ther | 2005 |
Clinical heart-lung transplantation.
Topics: Adult; Azathioprine; Cyclosporins; Female; Graft Rejection; Heart; Heart Defects, Congenital; Heart | 1984 |
Heart and lung transplantation for pulmonary hypertension.
Topics: Adult; Azathioprine; Cyclosporins; Female; Graft Rejection; Heart Transplantation; Heart-Lung Transp | 1984 |
Lung and heart-lung transplantation.
Topics: Adult; Animals; Azathioprine; Cyclosporins; Dogs; Eisenmenger Complex; Female; Graft Rejection; Hear | 1984 |
Remission of precapillary pulmonary hypertension in systemic lupus erythematosus.
Topics: Adult; Anti-Inflammatory Agents; Azathioprine; Female; Humans; Hypertension, Pulmonary; Immunosuppre | 2001 |
Isoproterenol as a potential pulmonary vasodilator in primary pulmonary hypertension.
Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Cardiac Catheterization; Cardiac Output; Diph | 1978 |
Pulmonary hypertension in a patient with diffuse fibrosing alveolitis due to rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Azathioprine; Humans; Hypertension, Pulmonary; Male; Pulmonary Fibrosi | 1986 |