azathioprine has been researched along with Hypersensitivity in 20 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypersensitivity reactions to 6-mercaptopurine (6-MP) or azathioprine occur during the treatment of inflammatory bowel disease (IBD), raising significant diagnostic and therapeutic challenges." | 7.70 | Allergic reactions to 6-mercaptopurine during treatment of inflammatory bowel disease. ( Fuller, S; Goel, F; Korelitz, BI; Zlatanic, J, 1999) |
| "Hypersensitivity reactions to 6-mercaptopurine (6-MP) or azathioprine occur during the treatment of inflammatory bowel disease (IBD), raising significant diagnostic and therapeutic challenges." | 3.70 | Allergic reactions to 6-mercaptopurine during treatment of inflammatory bowel disease. ( Fuller, S; Goel, F; Korelitz, BI; Zlatanic, J, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (95.00) | 18.7374 |
| 1990's | 1 (5.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KIRKPATRICK, CH | 2 |
| WILSON, WE | 2 |
| TALMAGE, DW | 2 |
| STEINER, B | 1 |
| NABRADY, J | 1 |
| BICKS, RO | 1 |
| BROWN, G | 1 |
| HICKEY, HD | 1 |
| ROSENBERG, EW | 1 |
| MAIBACH, HI | 1 |
| EPSTEIN, WL | 1 |
| MacKechnie, HL | 1 |
| Korelitz, BI | 1 |
| Zlatanic, J | 1 |
| Goel, F | 1 |
| Fuller, S | 1 |
| Benfield, JR | 1 |
| Shors, E | 1 |
| Schick, P | 1 |
| Byfield, PE | 1 |
| Okita, M | 1 |
| Sachar, DB | 1 |
| Taub, RN | 1 |
| Ramachandar, K | 1 |
| Meyers, S | 1 |
| Forman, SP | 1 |
| Douglas, SD | 1 |
| Janowitz, HD | 1 |
| Okuda, M | 1 |
| Eisner, JW | 1 |
| Fox, AE | 1 |
| Gawlak, DL | 1 |
| Ballantyne, DL | 1 |
| Freedman, HH | 1 |
| Nelson, DS | 1 |
| Herrlinger, JD | 1 |
| Müller-Ruchholtz, W | 1 |
| Lechner, K | 1 |
| Lyons, H | 1 |
| Pinn, VW | 1 |
| Cortell, S | 1 |
| Cohen, JJ | 1 |
| Harrington, JT | 1 |
| Meadow, SR | 1 |
| Glasgow, EF | 1 |
| White, RH | 1 |
| Moncrieff, MW | 1 |
| Cameron, JS | 1 |
| Ogg, CS | 1 |
| Hagedorn, M | 1 |
| Maas, D | 1 |
| Bilger, R | 1 |
| Mittermayer, C | 1 |
| Black, DA | 1 |
| Lee, AK | 1 |
| Mackay, IR | 1 |
| Rowley, MJ | 1 |
| Yap, CY | 1 |
5 reviews available for azathioprine and Hypersensitivity
| Article | Year |
|---|---|
The immunology of inflammatory bowel disease.
Topics: Azathioprine; Colitis, Ulcerative; Complement System Proteins; Crohn Disease; Humans; Hypersensitivi | 1982 |
[Wegener's granulomatosis].
Topics: Azathioprine; Cyclophosphamide; Drug Therapy, Combination; Eye; Granulomatosis with Polyangiitis; Hu | 1985 |
Drugs used in allergic states and their mode of action.
Topics: Anti-Inflammatory Agents; Asthma; Azathioprine; Catecholamines; Cromolyn Sodium; Drug-Related Side E | 1973 |
Acquired inhibitors in nonhemophilic patients.
Topics: Arthritis, Rheumatoid; Azathioprine; Blood Coagulation Disorders; Blood Coagulation Tests; Blood Pro | 1974 |
Immunosuppressive agents in protein-losing nephritis.
Topics: Animals; Azathioprine; Cyclophosphamide; Disease Models, Animal; Glomerulonephritis; Humans; Hyperse | 1970 |
15 other studies available for azathioprine and Hypersensitivity
| Article | Year |
|---|---|
IMMUNOLOGIC STUDIES IN HUMAN ORGAN TRANSPLANTATION. I. OBSERVATION AND CHARACTERIZATION OF SUPPRESSED CUTANEOUS REACTIVITY IN UREMIA.
Topics: Adrenal Cortex Hormones; Antigen-Antibody Reactions; Antigens; Azathioprine; Candida; Glomerulonephr | 1964 |
[IMMUNOALLERGIC PULMONARY HEMORRHAGE TREATED WITH IMURAN. (PRELIMINARY REPORT)].
Topics: Adolescent; Antineoplastic Agents; Azathioprine; Dexamethasone; Drug Therapy; Hemoptysis; Hemorrhage | 1964 |
IMMUNOLOGIC STUDIES IN HUMAN ORGAN TRANSPLANTATION. 3. THE RELATIONSHIP OF DELAYED CUTANEOUS HYPERSENSITIVITY TO THE ONSET OF ATTEMPTED KIDNEY ALLOGRAFT REJECTION.
Topics: Adolescent; Allografts; Antigen-Antibody Reactions; Azathioprine; Child; Dactinomycin; Drug Therapy; | 1964 |
FURTHER OBSERVATIONS ON A DELAYED HYPERSENSITIVITY REACTION IN THE GUINEA PIG COLON.
Topics: Allergens; Allergy and Immunology; Animals; Azathioprine; Colon; Guinea Pigs; Hypersensitivity; Hype | 1965 |
IMMUNOLOGIC RESPONSES OF HEALTHY VOLUNTEERS RECEIVING AZATHIOPRINE (IMURAN).
Topics: Aniline Compounds; Antimetabolites; Azathioprine; Biomedical Research; Dermatitis, Contact; Drug The | 1965 |
Allergic reactions to 6-mercaptopurine during treatment of inflammatory bowel disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Azathioprine; Desensitization, Immunologic; Female; Huma | 1999 |
Monitoring of immunosuppression in beagles.
Topics: Animals; Antibodies; Azathioprine; Carcinoma, Bronchogenic; Dinitrochlorobenzene; Disease Models, An | 1977 |
T and B lymphocytes and cutaneous anergy in inflammatory bowel disease.
Topics: Azathioprine; B-Lymphocytes; Colitis, Ulcerative; Crohn Disease; Dinitrochlorobenzene; Humans; Hyper | 1976 |
Influence of oxisuran, a differential inhibitor of cell-mediated hypersensitivity, on allograft survival and humoral immunity.
Topics: Animals; Antibody Formation; Azathioprine; Dogs; Female; Graft Rejection; Graft vs Host Reaction; He | 1973 |
Immunological aspects of organ and tissue transplantation.
Topics: Adrenal Cortex Hormones; Animals; Antigen-Antibody Reactions; Antigens; Antilymphocyte Serum; Arthus | 1968 |
[Inhibition of antibody formation in sensitized animals. II. Comparison of cyclophosphamide and azathioprine in antigen-cystostatic combination therapy].
Topics: Animals; Antibody Formation; Antigens; Azathioprine; Cyclophosphamide; Desensitization, Immunologic; | 1974 |
Allergic interstitial nephritis causing reversible renal failure in four patients with idiopathic nephrotic syndrome.
Topics: Acute Kidney Injury; Adult; Azathioprine; Chlorothiazide; Drug Hypersensitivity; Eosinophils; Female | 1973 |
Schönlein-Henoch nephritis.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Azathioprine; Basement Membrane; Child; Child, Preschool | 1973 |
[Papulosis atrophicans maligna (Köhlmeier-Degos) and Wegener's granulomatosis in a sister and brother (author's transl)].
Topics: Adrenal Cortex Hormones; Aged; Azathioprine; Cyclophosphamide; Diet Therapy; Female; Glutens; Granul | 1974 |
Measurement of antibody-producing capacity to flagellin in man. IV. Studies in autoimmune disease, allergy and after azathioprine treatment.
Topics: Animals; Antibody Formation; Antigens, Bacterial; Arthritis, Rheumatoid; Asthma; Autoimmune Diseases | 1971 |