azathioprine has been researched along with Hyperlipidemias in 25 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hyperlipidemias: Conditions with excess LIPIDS in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The possibility that hyperlipidemia and an increase of mononuclear cells in the glomeruli could participate in the pathogenesis of minimal change glomerulopathy was evaluated in puromycin aminonucleoside (PAN) nephrosis in rats." | 7.69 | The possible roles of hyperlipidemia and mononuclear cells in glomeruli in puromycin aminonucleoside nephrosis in rats. ( Hattori, T; Ito, M; Nagamatsu, T; Suzuki, Y, 1996) |
| "We studied rejection, allograft function and side effects, such as hypertension, renal dysfunction and hypercholesterolemia, in seven patients switched from cyclosporine-based triple-drug immunosuppression to FK 506." | 3.69 | Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506. ( Armitage, JM; Fricker, FJ; Swenson, JM, 1995) |
| "The possibility that hyperlipidemia and an increase of mononuclear cells in the glomeruli could participate in the pathogenesis of minimal change glomerulopathy was evaluated in puromycin aminonucleoside (PAN) nephrosis in rats." | 3.69 | The possible roles of hyperlipidemia and mononuclear cells in glomeruli in puromycin aminonucleoside nephrosis in rats. ( Hattori, T; Ito, M; Nagamatsu, T; Suzuki, Y, 1996) |
| "Atherogenic hypercholesteremia was found as frequently in patients on CyA as in those on Aza/P." | 2.66 | [Cyclosporin A and hyperlipidemia after kidney transplantation. Prospective study]. ( Brunner, FP; Hodel, K; Mordasini, RC; Thiel, G, 1986) |
| "Hyperlipidemia, long recognized as a difficult and common problem following organ transplantation, may be the underlying cause of the accelerated atherosclerosis observed in heart transplant recipients and children with renal transplants." | 2.38 | Hyperlipidemia after organ transplantation. ( Friedman, EA; Markell, MS, 1989) |
| "Tacrolimus-treated patients had a lower insignificant incidence of hyperlipidemia (P=0." | 1.35 | Long-term graft outcome in patients with chronic allograft dysfunction after immunosuppression modifications. ( El-Agroudy, AE; El-Baz, M; El-Dahshan, K; Ghoneim, MA; Mahmoud, K; Shokeir, AA, 2008) |
| "Persistent hyperlipidemia was defined as one-year average steady-state cholesterol (CavCHOL) or triglyceride (CavTG) concentrations above 240 and 200 mg/dL, respectively." | 1.33 | Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation. ( Casarini, DE; Felipe, CR; Garcia, R; Machado, PG; Medina-Pestana, JO; Moreira, SR; Park, SI; Spinelli, GA; Tedesco-Silva, H, 2006) |
| "Tacrolimus has improved hyperlipidaemia in our cyclosporin previously treated patients and increased the resistance to oxidation of high and low-density lipoproteins." | 1.31 | [Effect of cyclosporin and tacrolimus on lipoprotein oxidation after renal transplantation]. ( Alsina, J; Fiol, C; Gil-Vernet, S; Gómez-Gerique, N; Grinyó, JM; Hurtado, I; Martínez Castelao, A; Ramos, R; Sabaté, I; Serón, D; Yzaguirre, MT, 2002) |
| "(4) Sirolimus has numerous adverse effects, including hyperlipidemia, thrombocytopenia, hepatic disorders and opportunistic infections." | 1.31 | Sirolimus: new preparation. No tangible advance in renal transplantation. ( , 2002) |
| "Tacrolimus is a potent immunosuppressive agent that provides higher freedom from acute and chronic rejection than cyclosporine after liver transplantation (LTx)." | 1.31 | Reasons for long-term use of steroid in primary adult liver transplantation under tacrolimus. ( Fung, JJ; Jain, A; Kashyap, R; Khanna, A; Marsh, W; Rohal, S, 2001) |
| "Hypertension is a common concomitant condition in renal transplant recipients." | 1.30 | Hypertension is associated with hyperlipidemia, coronary heart disease and chronic graft failure in kidney transplant recipients. ( Bölscher, S; Geiger, H; Kachel, HG; Lenz, T; Peschke, B; Scheuermann, EH, 1999) |
| "The prevalence of hyperlipidemia in adolescents and young adults who are long-term survivors of pediatric renal transplantation with stable graft function has not previously been examined." | 1.29 | Hyperlipidemia in long-term survivors of pediatric renal transplantation. ( Hunninghake, DB; Kashtan, CE; Matas, AJ; Myers, TA; Sharma, AK, 1994) |
| " CsA dosage remained unchanged in the range of 200 mg/m2/day; CsA whole blood trough level was 120 to 130 ng/mL throughout the years." | 1.28 | Long-term results of cyclosporin A therapy in children. ( Bökenkamp, A; Brodehl, J; Hoyer, PF; Offner, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (36.00) | 18.7374 |
| 1990's | 8 (32.00) | 18.2507 |
| 2000's | 8 (32.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| El-Agroudy, AE | 1 |
| El-Dahshan, K | 1 |
| Mahmoud, K | 1 |
| El-Baz, M | 1 |
| Shokeir, AA | 1 |
| Ghoneim, MA | 1 |
| Martínez Castelao, A | 1 |
| Ramos, R | 1 |
| Serón, D | 1 |
| Gil-Vernet, S | 1 |
| Fiol, C | 1 |
| Gómez-Gerique, N | 1 |
| Yzaguirre, MT | 1 |
| Hurtado, I | 1 |
| Sabaté, I | 1 |
| Alsina, J | 1 |
| Grinyó, JM | 1 |
| Kari, JA | 1 |
| Trompeter, RS | 1 |
| Spinelli, GA | 1 |
| Felipe, CR | 1 |
| Machado, PG | 1 |
| Garcia, R | 1 |
| Casarini, DE | 1 |
| Moreira, SR | 1 |
| Park, SI | 1 |
| Tedesco-Silva, H | 1 |
| Medina-Pestana, JO | 1 |
| Swenson, JM | 1 |
| Fricker, FJ | 1 |
| Armitage, JM | 1 |
| Hilbrands, LB | 1 |
| Demacker, PN | 1 |
| Hoitsma, AJ | 1 |
| Stalenhoef, AF | 1 |
| Koene, RA | 1 |
| Zezina, L | 1 |
| Rosental, R | 1 |
| Sharma, AK | 1 |
| Myers, TA | 1 |
| Hunninghake, DB | 1 |
| Matas, AJ | 1 |
| Kashtan, CE | 1 |
| Hattori, T | 1 |
| Nagamatsu, T | 1 |
| Ito, M | 1 |
| Suzuki, Y | 1 |
| Peschke, B | 1 |
| Scheuermann, EH | 1 |
| Geiger, H | 1 |
| Bölscher, S | 1 |
| Kachel, HG | 1 |
| Lenz, T | 1 |
| Manu, M | 1 |
| Tanabe, K | 1 |
| Tokumoto, T | 1 |
| Ishikawa, N | 1 |
| Shimizu, T | 1 |
| Okuda, H | 1 |
| Ito, S | 1 |
| Shimmura, H | 1 |
| Inui, M | 1 |
| Harano, M | 1 |
| Shiroyanagi, Y | 1 |
| Yagisawa, T | 1 |
| Fuchinoue, S | 1 |
| Toma, H | 1 |
| Tur, MD | 1 |
| Garrigue, V | 1 |
| Vela, C | 1 |
| Dupuy, AM | 1 |
| Descomps, B | 1 |
| Cristol, JP | 1 |
| Mourad, G | 1 |
| Jain, A | 1 |
| Kashyap, R | 1 |
| Marsh, W | 1 |
| Rohal, S | 1 |
| Khanna, A | 1 |
| Fung, JJ | 1 |
| Beaumont, JE | 1 |
| Galla, JH | 1 |
| Luke, RG | 1 |
| Rees, ED | 1 |
| Siegel, RR | 1 |
| Rambaldi, M | 1 |
| Russo, R | 1 |
| Iaquinto, G | 1 |
| Agozzino, L | 1 |
| De Cristofano, R | 1 |
| Brodehl, J | 1 |
| Bökenkamp, A | 1 |
| Hoyer, PF | 1 |
| Offner, G | 1 |
| Isoniemi, H | 1 |
| Tikkanen, M | 1 |
| Häyry, P | 1 |
| Eklund, B | 1 |
| Höckerstedt, K | 1 |
| Salmela, K | 1 |
| Ahonen, J | 1 |
| Markell, MS | 1 |
| Friedman, EA | 1 |
| Vathsala, A | 1 |
| Weinberg, RB | 1 |
| Schoenberg, L | 1 |
| Grevel, J | 1 |
| Dunn, J | 1 |
| Goldstein, RA | 1 |
| Van Buren, CT | 1 |
| Lewis, RM | 1 |
| Kahan, BD | 1 |
| Hodel, K | 1 |
| Mordasini, RC | 1 |
| Brunner, FP | 1 |
| Thiel, G | 1 |
| Warnes, TW | 1 |
| Lower, RR | 1 |
| Houtsmuller, AJ | 1 |
| Greene, ML | 1 |
| Glueck, CJ | 1 |
| Fujimoto, WY | 1 |
| Seegmiller, JE | 1 |
5 reviews available for azathioprine and Hyperlipidemias
| Article | Year |
|---|---|
What is the calcineurin inhibitor of choice for pediatric renal transplantation?
Topics: Azathioprine; Calcineurin Inhibitors; Child; Clinical Trials as Topic; Cyclosporine; Growth and Deve | 2004 |
[Pancreatitis caused by drugs].
Topics: Adult; Azathioprine; Chlorothiazide; Contraceptives, Oral; Drug-Related Side Effects and Adverse Rea | 1977 |
Hyperlipidemia after organ transplantation.
Topics: Azathioprine; Cyclosporins; Humans; Hyperlipidemias; Kidney Transplantation; Lipoproteins; Prednison | 1989 |
Treatment of primary biliary cirrhosis.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Chlorambucil; Cholelithiasis; Colchicine | 1985 |
Current status of clinical cardiac transplantation.
Topics: Adult; Arteriosclerosis; Azathioprine; B-Lymphocytes; Brain Death; Cardiac Catheterization; Cardiomy | 1974 |
5 trials available for azathioprine and Hyperlipidemias
| Article | Year |
|---|---|
The effects of cyclosporine and prednisone on serum lipid and (apo)lipoprotein levels in renal transplant recipients.
Topics: Adult; Apolipoproteins; Arteriosclerosis; Azathioprine; Cholesterol, HDL; Cyclosporine; Female; Graf | 1995 |
Dislipidemia at different immunosuppressive protocols.
Topics: Azathioprine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cyclosporine; Fatty Acids, Nonesterif | 1994 |
Lipid profiles with triple drug immunosuppressive therapy and with double drug combinations after renal transplantation and stable graft function.
Topics: Azathioprine; Cyclosporins; Drug Therapy, Combination; Humans; Hypercholesterolemia; Hyperlipidemias | 1991 |
[Cyclosporin A and hyperlipidemia after kidney transplantation. Prospective study].
Topics: Adult; Azathioprine; Cyclosporins; Female; Humans; Hypercholesterolemia; Hyperlipidemias; Immunosupp | 1986 |
[Various internal medicine aspects of the future therapy for diabetic retinopathy].
Topics: Adult; Antineoplastic Agents; Azathioprine; Clofibrate; Diabetic Retinopathy; Female; Growth Hormone | 1972 |
15 other studies available for azathioprine and Hyperlipidemias
| Article | Year |
|---|---|
Long-term graft outcome in patients with chronic allograft dysfunction after immunosuppression modifications.
Topics: Adult; Azathioprine; Cyclosporine; Diabetes Mellitus; Drug Therapy, Combination; Female; Follow-Up S | 2008 |
[Effect of cyclosporin and tacrolimus on lipoprotein oxidation after renal transplantation].
Topics: Adult; Antihypertensive Agents; Apolipoproteins B; Arteriosclerosis; Azathioprine; Cholesterol; Cycl | 2002 |
Sirolimus: new preparation. No tangible advance in renal transplantation.
Topics: Azathioprine; Clinical Trials as Topic; Cyclosporine; Drug Approval; Drug Therapy, Combination; Euro | 2002 |
Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation.
Topics: Adult; Azathioprine; Cyclosporine; Drug Administration Schedule; Drug Therapy, Combination; Female; | 2006 |
Immunosuppression switch in pediatric heart transplant recipients: cyclosporine to FK 506.
Topics: Adolescent; Adult; Antihypertensive Agents; Azathioprine; Cardiac Catheterization; Child; Cyclospori | 1995 |
Hyperlipidemia in long-term survivors of pediatric renal transplantation.
Topics: Adolescent; Adult; Azathioprine; Child; Child, Preschool; Cholesterol; Cholesterol, HDL; Cohort Stud | 1994 |
The possible roles of hyperlipidemia and mononuclear cells in glomeruli in puromycin aminonucleoside nephrosis in rats.
Topics: Animals; Anticholesteremic Agents; Azathioprine; CD4-Positive T-Lymphocytes; Cholestyramine Resin; C | 1996 |
Hypertension is associated with hyperlipidemia, coronary heart disease and chronic graft failure in kidney transplant recipients.
Topics: Azathioprine; Coronary Disease; Cyclosporine; Graft Rejection; Humans; Hyperlipidemias; Hypertension | 1999 |
Impact of tacrolimus on hyperlipidemia after renal transplantation: a Japanese single center experience.
Topics: Adult; Azathioprine; Cholesterol; Cholesterol, HDL; Cyclosporine; Drug Therapy, Combination; Female; | 2000 |
Apolipoprotein CIII is upregulated by anticalcineurins and rapamycin: implications in transplantation-induced dyslipidemia.
Topics: Adult; Apolipoprotein C-III; Apolipoproteins A; Apolipoproteins B; Apolipoproteins C; Azathioprine; | 2000 |
Reasons for long-term use of steroid in primary adult liver transplantation under tacrolimus.
Topics: Adult; Azathioprine; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Hyperlipidemias; Hyperten | 2001 |
Normal serum-lipids in renal-transplant patients.
Topics: Adolescent; Adult; Age Factors; Antigens; Azathioprine; Body Weight; Cholesterol; Creatine; Fasting; | 1975 |
Long-term results of cyclosporin A therapy in children.
Topics: Adolescent; Antihypertensive Agents; Azathioprine; Child; Child, Preschool; Cyclosporine; Female; Fo | 1992 |
Lipid abnormalities in renal transplant recipients treated with cyclosporine.
Topics: Adult; Azathioprine; Cholesterol; Cyclosporins; Drug Therapy, Combination; Female; Humans; Hyperlipi | 1989 |
Benign symmetric lipomatosis (Launois-Bensaude adenolipomatosis) with gout and hyperlipoproteinemia.
Topics: Adult; Azathioprine; Blood Protein Electrophoresis; Carbon Isotopes; Female; Glucose Tolerance Test; | 1970 |