azathioprine has been researched along with Hodgkin Disease in 32 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hodgkin Disease: A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Azathioprine was withdrawn." | 1.40 | Hodgkin's lymphoma rectosigmoid in a patient with ulcerative colitis on long-term azathioprine therapy. ( Khuroo, MS, 2014) |
| "The link between ulcerative colitis, the chronic hepatopathy and the development of Hodgkin's disease that could have arisen as a consequence of the prolonged immunosuppressive treatment are discussed." | 1.26 | [Hodgkin's disease developing in the course of a chronic liver disease with ulcerative colitis immunosuppressed with azathioprine]. ( Findor, JA; Orbuch, SJ, 1979) |
| "Thirteen patients with Wegener's granulomatosis have been treated with cytotoxic agents." | 1.25 | Treatment of Wegener's granulomatosis of lung. ( Isreal, HL; Patchfsky, AS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (65.63) | 18.7374 |
| 1990's | 1 (3.13) | 18.2507 |
| 2000's | 3 (9.38) | 29.6817 |
| 2010's | 7 (21.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Henkenberens, C | 1 |
| Franzke, A | 1 |
| Raab, P | 1 |
| Oschlies, I | 1 |
| Klapper, W | 1 |
| Christiansen, H | 1 |
| Khuroo, MS | 1 |
| Hsu, WY | 1 |
| Chiou, SS | 1 |
| Liao, YM | 1 |
| Shu, HL | 1 |
| Zeng, YS | 1 |
| Wong, CC | 1 |
| Lin, PC | 1 |
| Adams, B | 1 |
| Lazarchick, J | 1 |
| Medina, AM | 1 |
| Willner, IR | 1 |
| Neville, B | 1 |
| Murphy, E | 1 |
| Stuart, R | 1 |
| Costa, LJ | 1 |
| Sagüés, M | 1 |
| Navarro, JT | 1 |
| Ribera, JM | 1 |
| Millá, F | 1 |
| Rojas-Feria, M | 1 |
| Eslam, M | 1 |
| Castro-Fernández, M | 1 |
| Guerrero, P | 1 |
| Larraona-Moreno, JL | 1 |
| Romero-Gómez, M | 1 |
| Bernatsky, S | 1 |
| Ramsey-Goldman, R | 1 |
| Joseph, L | 1 |
| Boivin, JF | 1 |
| Costenbader, KH | 1 |
| Urowitz, MB | 1 |
| Gladman, DD | 1 |
| Fortin, PR | 1 |
| Nived, O | 1 |
| Petri, MA | 1 |
| Jacobsen, S | 1 |
| Manzi, S | 1 |
| Ginzler, EM | 1 |
| Isenberg, D | 1 |
| Rahman, A | 1 |
| Gordon, C | 1 |
| Ruiz-Irastorza, G | 1 |
| Yelin, E | 1 |
| Bae, SC | 1 |
| Wallace, DJ | 1 |
| Peschken, CA | 1 |
| Dooley, MA | 1 |
| Edworthy, SM | 1 |
| Aranow, C | 1 |
| Kamen, DL | 1 |
| Romero-Diaz, J | 1 |
| Askanase, A | 1 |
| Witte, T | 1 |
| Barr, SG | 1 |
| Criswell, LA | 1 |
| Sturfelt, GK | 1 |
| Blanco, I | 1 |
| Feldman, CH | 1 |
| Dreyer, L | 1 |
| Patel, NM | 1 |
| St Pierre, Y | 1 |
| Clarke, AE | 1 |
| Tchuenbou, J | 1 |
| de Muret, A | 1 |
| Dumont, P | 1 |
| Bacq, Y | 1 |
| Patel, P | 1 |
| Moazzam, N | 1 |
| Potti, A | 1 |
| Mehdi, SA | 1 |
| Evans, SJ | 1 |
| Watson, DK | 1 |
| O'Sullivan, M | 1 |
| Geary, CG | 1 |
| Bradley, SJ | 1 |
| Hudson, GV | 1 |
| Linch, DC | 1 |
| Verhaegen, H | 1 |
| De Cock, W | 1 |
| De Cree, J | 1 |
| Verbruggen, F | 1 |
| Verhaegen-Declercq, M | 1 |
| Brugmans, J | 1 |
| Sieber, SM | 1 |
| Orbuch, SJ | 1 |
| Findor, JA | 1 |
| Isreal, HL | 1 |
| Patchfsky, AS | 1 |
| Colburn, KK | 1 |
| Cao, JD | 1 |
| Krick, EH | 1 |
| Mortensen, SE | 1 |
| Wong, LG | 1 |
| Stinner, G | 1 |
| Boden, B | 1 |
| Fünfhausen, G | 1 |
| Gleason, TH | 1 |
| Hamlin, WB | 1 |
| Pauly, JL | 1 |
| Han, T | 1 |
| Varkarakis, MJ | 1 |
| Sokal, JE | 1 |
| Sampson, D | 1 |
| Murphy, GP | 1 |
| Butler, DJ | 1 |
| Thompson, H | 1 |
| Michlmayr, G | 1 |
| Günther, R | 1 |
| Lederer, B | 1 |
| Huber, H | 1 |
| Harrison, DF | 1 |
| Pirotte, JH | 1 |
| Casey, TP | 1 |
| Haim, S | 1 |
| Shafrir, A | 1 |
| Better, OS | 1 |
| Robinson, E | 1 |
| Chaimowitz, C | 1 |
| Erlik, D | 1 |
| Sterling, WA | 1 |
| Wu, LY | 1 |
| Dowling, EA | 1 |
| Diethelm, AG | 1 |
| Thomas, F | 1 |
| Owens, L | 1 |
| Thomas, J | 1 |
| Wolf, JS | 1 |
| Volk, M | 1 |
| Mendez, G | 1 |
| Lee, HM | 1 |
| Krueger, GR | 2 |
| Heine, UI | 1 |
| Convit, J | 1 |
| Kerdel, F | 1 |
| Goihman, M | 1 |
| Rondon, AJ | 1 |
| Soto, JM | 1 |
| Corder, MP | 1 |
| Young, RC | 1 |
| DeVita, VT | 1 |
| Malmgren, RA | 1 |
| Berard, CW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hydroxychloroquine Exposure in Systemic Lupus Erythematosus (SLE)[NCT03802188] | 3,700 participants (Anticipated) | Observational | 2018-05-09 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for azathioprine and Hodgkin Disease
| Article | Year |
|---|---|
Primary EBV-positive Hodgkin's lymphoma of the CNS under azathioprine treatment: case report and review of the literature.
Topics: Azathioprine; Cerebellar Neoplasms; Chemoradiotherapy, Adjuvant; Combined Modality Therapy; Cranioto | 2014 |
Azathioprine induced hodgkin lymphoma: a case report and review of literature.
Topics: Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Hodgkin Disease; Humans; Immunosuppres | 2005 |
Idiopathic thrombocytopenic purpura in Hodgkin's disease: a report of eight cases.
Topics: Adult; Azathioprine; Female; Follow-Up Studies; Hodgkin Disease; Humans; Male; Prednisolone; Purpura | 1993 |
The action of antitumor agents: a double-edged sword?
Topics: Alkylating Agents; Animals; Antineoplastic Agents; Azathioprine; Burkitt Lymphoma; Choriocarcinoma; | 1977 |
28 other studies available for azathioprine and Hodgkin Disease
| Article | Year |
|---|---|
Hodgkin's lymphoma rectosigmoid in a patient with ulcerative colitis on long-term azathioprine therapy.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Azathioprine; Colitis, Ulcerative; Hodgkin Dis | 2014 |
Successful management of multilineage autoimmune cytopenia complicated with severe infection and deep vein thrombosis in a patient with Hodgkin lymphoma post-autologous hematopoietic stem cell transplantation.
Topics: Adolescent; Autoimmune Diseases; Azathioprine; Bone Marrow Transplantation; Cell Lineage; Cyclophosp | 2016 |
Iatrogenic immunodeficiency-associated lymphoproliferative disease of the Hodgkin lymphoma-like variant in a patient treated with mycophenolate mofetil for autoimmune hepatitis.
Topics: Adult; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Azathioprine; Diagnosis, Diff | 2010 |
[Hodgkin's lymphoma in a patient with Crohn's disease treated with azathioprine and antibodies anti tumor necrosis factor α].
Topics: Azathioprine; Crohn Disease; Hodgkin Disease; Humans; Immunosuppressive Agents; Male; Tumor Necrosis | 2012 |
Cutaneous lymphoma in a patient with ulcerative colitis after immunosuppressive therapy.
Topics: Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Azathioprine; Colitis, Ulcerative; Hodgkin D | 2011 |
Lymphoma risk in systemic lupus: effects of disease activity versus treatment.
Topics: Adult; Antimalarials; Azathioprine; Case-Control Studies; Cyclophosphamide; Female; Glucocorticoids; | 2014 |
[Hodgkin's disease during azathioprine therapy in a patient with autoimmune hepatitis].
Topics: Aged; Azathioprine; Female; Hepatitis, Autoimmune; Hodgkin Disease; Humans; Immunosuppressive Agents | 2004 |
Reversible Hodgkin's lymphoma associated with Epstein-Barr virus occurring during azathioprine therapy for SLE.
Topics: Azathioprine; Epstein-Barr Virus Infections; Female; Hodgkin Disease; Humans; Immunosuppressive Agen | 2008 |
Lymphoma and leukaemia due to drugs.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Bone Marrow Diseases; Child; Female; Hodgkin Disease; | 1980 |
Letter: In-vitro restoration by levamisole of thymus-derived lymphocyte functions in Hodgkin's disease.
Topics: Azathioprine; Dose-Response Relationship, Drug; Drug Antagonism; Hodgkin Disease; Humans; Immune Adh | 1975 |
[Hodgkin's disease developing in the course of a chronic liver disease with ulcerative colitis immunosuppressed with azathioprine].
Topics: Azathioprine; Colitis, Ulcerative; Hepatitis B; Hepatitis B Surface Antigens; Hodgkin Disease; Human | 1979 |
Treatment of Wegener's granulomatosis of lung.
Topics: Azathioprine; Cyclophosphamide; Drug Evaluation; Granuloma; Granulomatosis with Polyangiitis; Hodgki | 1975 |
Hodgkin's lymphoma in a patient treated for Wegener's granulomatosis with cyclophosphamide and azathioprine.
Topics: Azathioprine; Cyclophosphamide; Granulomatosis with Polyangiitis; Hodgkin Disease; Humans; Male; Mid | 1985 |
[Serological studies after homologous bone marrow transfusion].
Topics: Adult; Autoradiography; Azathioprine; Blood Group Antigens; Bone Marrow Transplantation; Female; Hem | 1969 |
Disseminated toxoplasmosis in the compromised host. A report of five cases.
Topics: Adult; Aged; Anemia, Hemolytic, Autoimmune; Autopsy; Azathioprine; Brain; Breast Neoplasms; Female; | 1974 |
Leukocyte (3H) thymidine uptake in short-term whole-blood cultures of human and canine renal allograft recipients.
Topics: Animals; Azathioprine; Cadaver; Dogs; Graft Rejection; Hodgkin Disease; Humans; Immunity, Cellular; | 1973 |
Malignant granuloma.
Topics: Adrenocorticotropic Hormone; Adult; Alveolar Process; Arteritis; Autopsy; Azathioprine; Biopsy; Gran | 1972 |
[Malignant lymphoma following two years' of immunosuppressive therapy for periarteritis nodosa].
Topics: Agammaglobulinemia; Azathioprine; Female; Hodgkin Disease; Humans; Middle Aged; Polyarteritis Nodosa | 1973 |
Non-healing granulomata of the upper respiratory tract.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Azathioprine; Blood Sedimentation; Child; Female; | 1974 |
Development of Hodgkins disease in the course of active chronic hepatitis treated by immunosuppressive drugs.
Topics: Adult; Azathioprine; Biopsy; Chronic Disease; Female; Hepatitis; Hodgkin Disease; Humans; Immunosupp | 1974 |
Azathioprine administration to NZB X NZW hybrid mice with lupus nephritis: beneficial effect complicated by development of malignant lymphomas.
Topics: Animals; Autoantibodies; Autoimmune Diseases; Azathioprine; Body Weight; Female; Hodgkin Disease; Ki | 1973 |
Kaposi's sarcoma in association with immunosuppressive therapy. Report of two cases.
Topics: Adult; Aged; Azathioprine; Hodgkin Disease; Humans; Immunosuppressive Agents; Kidney Transplantation | 1972 |
Hodgkin's disease in a renal transplant recipient. A case report.
Topics: Antilymphocyte Serum; Autopsy; Azathioprine; B-Lymphocytes; Cytotoxicity Tests, Immunologic; Hodgkin | 1974 |
Differential effect of immunosuppressive agents on T and B lymphocytes.
Topics: Animals; Antilymphocyte Serum; Azathioprine; B-Lymphocytes; Bacterial Infections; Concanavalin A; De | 1974 |
Morphogenesis of two immunologically induced mouse lymphomas.
Topics: Animals; Azathioprine; Cells, Cultured; Female; Hodgkin Disease; Liver; Lung; Lymph Nodes; Mice; Mic | 1972 |
Progressive, atrophying, chronic granulomatous dermohypodermitis. Autoimmune disease?
Topics: Adult; Atrophy; Autoimmune Diseases; Axilla; Azathioprine; BCG Vaccine; Chronic Disease; Cutis Laxa; | 1973 |
Delayed hypersensitivity in patients with cancer.
Topics: Azathioprine; Croton Oil; Hodgkin Disease; Humans; Hypersensitivity, Delayed; Immunosuppressive Agen | 1971 |
Malignant lymphomas and plasmacytosis in mice under prolonged immunosuppression and persistent antigenic stimulation.
Topics: Animals; Antigens; Antilymphocyte Serum; Atrophy; Azathioprine; Female; Freund's Adjuvant; Glomerulo | 1971 |