azathioprine has been researched along with Herpes Simplex in 29 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Herpes Simplex: A group of acute infections caused by herpes simplex virus type 1 or type 2 that is characterized by the development of one or more small fluid-filled vesicles with a raised erythematous base on the skin or mucous membrane. It occurs as a primary infection or recurs due to a reactivation of a latent infection. (Dorland, 27th ed.)
| Excerpt | Relevance | Reference |
|---|---|---|
| " We report a case of disseminated cutaneous herpes simplex infection in a patient with Crohn's disease under steroids and azathioprine." | 8.90 | Disseminated cutaneous herpes simplex infection in a patient with Crohn's disease under azathioprine and steroids: First case report and literature review. ( Abreu, C; Andrade, P; Coelho, R; Lopes, S; Macedo, G; Magro, F; Santos-Antunes, J; Vilas-Boas, F, 2014) |
| "There are few data on the incidence of benign infections (upper respiratory tract infections, herpes lesions and viral warts) during exposure to azathioprine." | 7.75 | Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine. ( Beaugerie, L; Cosnes, J; Gendre, JP; Nion-Larmurier, I; Seksik, P; Sokol, H, 2009) |
| "This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)." | 7.70 | Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000) |
| " We report a case of disseminated cutaneous herpes simplex infection in a patient with Crohn's disease under steroids and azathioprine." | 4.90 | Disseminated cutaneous herpes simplex infection in a patient with Crohn's disease under azathioprine and steroids: First case report and literature review. ( Abreu, C; Andrade, P; Coelho, R; Lopes, S; Macedo, G; Magro, F; Santos-Antunes, J; Vilas-Boas, F, 2014) |
| " The variety of acute hepatitis include hepatitis A, hepatitis B, cytomegalovirus hepatitis, herpes simplex hepatitis and azathioprine hepatitis." | 4.75 | Liver disease in renal transplant recipients. ( Anuras, S; Sopko, J, 1978) |
| "There are few data on the incidence of benign infections (upper respiratory tract infections, herpes lesions and viral warts) during exposure to azathioprine." | 3.75 | Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine. ( Beaugerie, L; Cosnes, J; Gendre, JP; Nion-Larmurier, I; Seksik, P; Sokol, H, 2009) |
| "This paper presents the first report of the use of topical azathioprine in the management of persistent symptomatic chronic oral graft-versus-host disease (GVHD)." | 3.70 | Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease. ( Epstein, JB; Nantel, S; Sheoltch, SM, 2000) |
| "Pulmonary infections were less common in cyclosporine-treated renal patients than in Aza-treated patients (P less than 0." | 2.65 | Early infections in kidney, heart, and liver transplant recipients on cyclosporine. ( Dummer, JS; Hardy, A; Ho, M; Poorsattar, A, 1983) |
| "Recurrence was observed in 2 cases." | 1.30 | [Herpetic superinfection of pemphigus: 6 cases]. ( Azzouzi, S; el Ouazzani, T; Lakhdar, H; Sqalli, S; Zouhair, K, 1999) |
| "Recurrent erythema multiforme is an uncommon disorder." | 1.29 | Recurrent erythema multiforme: clinical features and treatment in a large series of patients. ( Leigh, IM; Schofield, JK; Tatnall, FM, 1993) |
| "0) at high prednisolone dosage compared to the lower incidence (CMV 54." | 1.27 | Cytomegalo and herpes simplex virus infections in renal transplant recipients. ( Geelen, JL; Slaterus, KW; van der Noordaa, J; Wertheim, P; Wilmink, JM, 1985) |
| "Two patients developed reticulum cell sarcomata after they had been treated with azathioprine and prednisone in the course of cadaveric renal transplantation." | 1.25 | Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy. ( Doak, PB; Montgomerie, JZ; North, JD; Smith, F, 1968) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (62.07) | 18.7374 |
| 1990's | 3 (10.34) | 18.2507 |
| 2000's | 4 (13.79) | 29.6817 |
| 2010's | 4 (13.79) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jensen, CH | 1 |
| Tiu, J | 1 |
| Catalanotti, JS | 1 |
| Hou, S | 1 |
| Santos-Antunes, J | 1 |
| Abreu, C | 1 |
| Magro, F | 1 |
| Coelho, R | 1 |
| Vilas-Boas, F | 1 |
| Andrade, P | 1 |
| Lopes, S | 1 |
| Macedo, G | 1 |
| Demitsu, T | 1 |
| Kakurai, M | 1 |
| Azuma, R | 1 |
| Hiratsuka, Y | 1 |
| Yamada, T | 1 |
| Yoneda, K | 1 |
| Seksik, P | 1 |
| Cosnes, J | 1 |
| Sokol, H | 1 |
| Nion-Larmurier, I | 1 |
| Gendre, JP | 1 |
| Beaugerie, L | 1 |
| Cottone, M | 1 |
| Renna, S | 1 |
| Ramaiya, KJ | 1 |
| Rao, PK | 1 |
| Park, RK | 1 |
| Goltz, RW | 1 |
| Carey, TB | 1 |
| Blyth, WA | 1 |
| Harbour, DA | 1 |
| Hill, TJ | 1 |
| Dummer, JS | 1 |
| Hardy, A | 1 |
| Poorsattar, A | 1 |
| Ho, M | 1 |
| Schofield, JK | 1 |
| Tatnall, FM | 1 |
| Leigh, IM | 1 |
| Zouhair, K | 1 |
| el Ouazzani, T | 1 |
| Azzouzi, S | 1 |
| Sqalli, S | 1 |
| Lakhdar, H | 1 |
| Epstein, JB | 1 |
| Nantel, S | 1 |
| Sheoltch, SM | 1 |
| Scheetz ME, II | 1 |
| Carlson, DG | 1 |
| Schinitsky, MR | 1 |
| Sopko, J | 1 |
| Anuras, S | 1 |
| Mozes, MF | 1 |
| Ascher, NL | 1 |
| Balfour, HH | 1 |
| Simmons, RL | 2 |
| Najarian, JS | 2 |
| Pass, RF | 1 |
| Whitley, RJ | 1 |
| Whelchel, JD | 1 |
| Diethelm, AG | 1 |
| Reynolds, DW | 1 |
| Alford, CA | 1 |
| Holdsworth, SR | 1 |
| Atkins, RC | 1 |
| Scott, DF | 1 |
| Hayes, K | 1 |
| Bogossian, M | 1 |
| Huraux, JM | 1 |
| Nicolas, JC | 1 |
| Begué, P | 1 |
| Bricout, F | 1 |
| Russell Jones, R | 1 |
| Tomlanovich, SJ | 1 |
| Sabatte-Caspillo, J | 1 |
| Melzer, J | 1 |
| Amend, W | 1 |
| Vincenti, F | 1 |
| Feduska, N | 1 |
| Salvatierra, O | 1 |
| Greger, B | 1 |
| Döller, G | 1 |
| Schareck, WD | 1 |
| Müller, GH | 1 |
| Mellert, J | 1 |
| Hopt, UT | 1 |
| Bockhorn, H | 1 |
| Gerken, G | 1 |
| Trautmann, F | 1 |
| Köhler, H | 1 |
| Falke, D | 1 |
| Bohl, J | 1 |
| Nix, W | 1 |
| Meyer zum Büschenfelde, KH | 1 |
| Wertheim, P | 1 |
| Slaterus, KW | 1 |
| Geelen, JL | 1 |
| van der Noordaa, J | 1 |
| Wilmink, JM | 1 |
| Spencer, ES | 1 |
| Andersen, HK | 1 |
| Lopez, C | 1 |
| Park, BH | 1 |
| Good, RA | 1 |
| Myers, BD | 1 |
| Kessler, E | 1 |
| Levi, J | 1 |
| Pick, A | 1 |
| Rosenfeld, JB | 1 |
| Tikvah, P | 1 |
| Hersh, EM | 1 |
| Freireich, EJ | 1 |
| Doak, PB | 1 |
| Montgomerie, JZ | 1 |
| North, JD | 1 |
| Smith, F | 1 |
3 reviews available for azathioprine and Herpes Simplex
| Article | Year |
|---|---|
Pregnancy in renal transplant recipients.
Topics: Anemia; Azathioprine; Cyclosporine; Cytomegalovirus Infections; Female; Herpes Simplex; Humans; Immu | 2013 |
Disseminated cutaneous herpes simplex infection in a patient with Crohn's disease under azathioprine and steroids: First case report and literature review.
Topics: Adrenal Cortex Hormones; Azathioprine; Crohn Disease; Drug Therapy, Combination; Female; Herpes Simp | 2014 |
Liver disease in renal transplant recipients.
Topics: Animals; Azathioprine; Budd-Chiari Syndrome; Chemical and Drug Induced Liver Injury; Cholestasis; Ch | 1978 |
1 trial available for azathioprine and Herpes Simplex
| Article | Year |
|---|---|
Early infections in kidney, heart, and liver transplant recipients on cyclosporine.
Topics: Adult; Azathioprine; Cyclosporins; Cytomegalovirus Infections; Female; Graft Survival; Heart Transpl | 1983 |
25 other studies available for azathioprine and Herpes Simplex
| Article | Year |
|---|---|
Azathioprine-induced pancytopenia with normal TPMT activity presenting with HSV oral ulcers.
Topics: Aged; Azathioprine; Herpes Simplex; Humans; Immunosuppressive Agents; Male; Methyltransferases; Oral | 2018 |
Recalcitrant pemphigus foliaceus with Kaposi's varicelliform eruption: report of a fatal case.
Topics: Aged, 80 and over; Azathioprine; Diagnosis, Differential; Drug Therapy, Combination; Fatal Outcome; | 2008 |
Incidence of benign upper respiratory tract infections, HSV and HPV cutaneous infections in inflammatory bowel disease patients treated with azathioprine.
Topics: Adolescent; Adult; Aged; Azathioprine; Cohort Studies; Female; Herpes Simplex; Humans; Immunosuppres | 2009 |
IBD: incidence of HSV and HPV with azathioprine.
Topics: Azathioprine; Herpes Simplex; Humans; Immunosuppressive Agents; Incidence; Inflammatory Bowel Diseas | 2009 |
Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant.
Topics: Acyclovir; Antiviral Agents; Azathioprine; Cataract; Drug Implants; Eye Infections, Viral; Herpes Si | 2011 |
Unusual cutaneous infections associated with immunosuppressive therapy.
Topics: Adolescent; Adult; Azathioprine; Chickenpox; Child; Female; Herpes Simplex; Histoplasmosis; Humans; | 1967 |
Effect of immunosuppression on recurrent herpes simplex in mice.
Topics: Animals; Antilymphocyte Serum; Azathioprine; Erythema; Female; Herpes Simplex; Hypersensitivity, Del | 1980 |
Recurrent erythema multiforme: clinical features and treatment in a large series of patients.
Topics: Acyclovir; Administration, Oral; Adolescent; Adult; Aged; Azathioprine; Child; Child, Preschool; Chr | 1993 |
[Herpetic superinfection of pemphigus: 6 cases].
Topics: Acyclovir; Adrenal Cortex Hormones; Adult; Aged; Antiviral Agents; Azathioprine; Cyclophosphamide; F | 1999 |
Topical azathioprine in the combined treatment of chronic oral graft-versus-host disease.
Topics: Administration, Topical; Adult; Anemia, Aplastic; Azathioprine; Bone Marrow Transplantation; Candidi | 2000 |
Frentizole, a novel immunosuppressive, and azathioprine: their comparative effects on host resistance to Pseudomonas aeruginosa, Candida albicans, herpes simplex virus, and influenza (Ann Arbor) virus.
Topics: Animals; Azathioprine; Benzothiazoles; Candida albicans; Candidiasis; Herpes Simplex; Immunosuppress | 1977 |
Jaundice after renal allotransplantation.
Topics: Adult; Alkaline Phosphatase; Aspartate Aminotransferases; Azathioprine; Bilirubin; Blood Transfusion | 1978 |
Identification of patients with increased risk of infection with herpes simplex virus after renal transplantation.
Topics: Antibodies, Viral; Antilymphocyte Serum; Azathioprine; Female; Herpes Simplex; Humans; Immunosuppres | 1979 |
Systemic herpes simplex infection with fulminant hepatitis post-transplantation.
Topics: Adolescent; Azathioprine; Hepatitis, Viral, Human; Herpes Simplex; Humans; Kidney Transplantation; M | 1976 |
[Experimental herpetic infection in rabbits combined with immunodepression (author's transl)].
Topics: Animals; Antibodies, Viral; Antibody Formation; Azathioprine; Disease Models, Animal; Herpes Simplex | 1975 |
Recurrent facial herpes associated with Chinese herbal remedy.
Topics: Adult; Azathioprine; Dermatitis, Atopic; Drugs, Chinese Herbal; Facial Dermatoses; Herpes Simplex; H | 1991 |
The incidence and impact of herpes simplex virus infections in the first month following renal transplantation.
Topics: Adult; Azathioprine; Cyclosporins; Female; Graft Rejection; Herpes Simplex; Humans; Kidney Transplan | 1989 |
Incidence and clinical course of CMV- (and herpes simplex-) infections under triple drug therapy.
Topics: Azathioprine; Cyclosporins; Cytomegalovirus Infections; Herpes Simplex; Humans; Immunosuppression Th | 1987 |
Rare association of herpes simplex virus IgM-specific antibodies and Guillain-Barré syndrome successfully treated with plasma exchange and immunosuppression.
Topics: Aged; Antibodies, Viral; Antibody Specificity; Azathioprine; Biopsy; Combined Modality Therapy; Herp | 1985 |
Cytomegalo and herpes simplex virus infections in renal transplant recipients.
Topics: Antibodies, Viral; Azathioprine; Cross Infection; Cytomegalovirus; Cytomegalovirus Infections; Drug | 1985 |
Clinically evident, non-terminal infections with herpesviruses and the wart virus in immunosuppressed renal allograft recipients.
Topics: Adolescent; Adult; Azathioprine; Child; Complement Fixation Tests; Cytomegalovirus Infections; Femal | 1970 |
Cell-mediated and humoral immune responses or renal transplant recipients with cytomegalovirus infections.
Topics: Antibody Formation; Azathioprine; Complement Fixation Tests; Cytomegalovirus Infections; Herpes Simp | 1974 |
Kaposi sarcoma in kidney transplant recipients.
Topics: Adult; Antilymphocyte Serum; Autopsy; Azathioprine; Brain Neoplasms; Cadaver; Female; Graft Rejectio | 1974 |
Editorial: Focus on cutaneous host-defense failure in transplant recipients.
Topics: Azathioprine; Graft Rejection; Herpes Simplex; Herpes Zoster; Humans; Immunity, Cellular; Immunosupp | 1974 |
Reticulum cell sarcoma after renal homotransplantation and azathioprine and prednisone therapy.
Topics: Adult; Azathioprine; Brain Neoplasms; Female; Herpes Simplex; Humans; Kidney Transplantation; Liver | 1968 |