azathioprine has been researched along with Hepatitis C, Chronic in 19 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hepatitis C, Chronic: INFLAMMATION of the LIVER in humans that is caused by HEPATITIS C VIRUS lasting six months or more. Chronic hepatitis C can lead to LIVER CIRRHOSIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The medical records of eight patients who developed severe pancytopenia following concomitant use of azathioprine and ribavirin were retrospectively reviewed." | 3.74 | Interaction of ribavirin with azathioprine metabolism potentially induces myelosuppression. ( Bigard, MA; Bronowicki, JP; Cadranel, JF; Canva, V; Cortot, A; Gueant, JL; Nousbaum, JB; Oussalah, A; Peyrin-Biroulet, L; Roblin, X; Seddik, M; Sogni, P, 2008) |
| "Factors associated with HCV recurrence were evaluated." | 2.79 | Reduced fibrosis in recurrent HCV with tacrolimus, azathioprine and steroids versus tacrolimus: randomised trial long term outcomes. ( Burroughs, AK; Cholongitas, E; Corbani, A; Davidson, B; Davidson, J; Dhillon, AP; Hayes, P; Luong, T; Manousou, P; McCormick, PA; O'Beirne, J; Patch, D; Rodríguez-Perálvarez, M; Rolles, K; Samonakis, D; Thorburn, D; Tsochatzis, E, 2014) |
| " Patients were randomized to the non-RTX group (to receive conventional treatment, consisting of 1 of the following 3: glucocorticoids; azathioprine or cyclophosphamide; or plasmapheresis) or the RTX group (to receive 2 infusions of 1 gm each, with a lowering of the glucocorticoid dosage when possible, and with a second course of RTX at relapse)." | 2.77 | A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis. ( Bombardieri, S; Campanini, M; De Vita, S; Ferri, C; Filippini, D; Gabrielli, A; Galli, M; Isola, M; Lenzi, M; Mascia, MT; Maset, M; Masolini, P; Mazzaro, C; Migliaresi, S; Monti, G; Naclerio, C; Perrella, O; Pietrogrande, M; Pioltelli, P; Quartuccio, L; Roccatello, D; Scaini, P; Tavoni, A; Zabotti, A; Zignego, AL, 2012) |
| "A total of 79 patients with hepatitis C, B, or both, transplanted between 1973 and 1990, were grouped according to whether they had AZA either withdrawn from the immunosuppressive regimen [group (G) I, n=45] or a dosage reduction only (group II, n=34)." | 2.69 | The impact of azathioprine on chronic viral hepatitis in renal transplantation: a long-term, single-center, prospective study on azathioprine withdrawal. ( Americo da Fonseca, J; David-Neto, E; Ianhez, LE; Jota de Paula, F; Nahas, WC; Sabbaga, E, 1999) |
| "Immunoglobulin G4 (IgG4)-associated autoimmune hepatitis (AIH) was recognized as a new disease entity; however, IgG4-associated de novo AIH after the liver transplantation had not been reported yet." | 2.49 | Immunoglobulin G4-associated de novo autoimmune hepatitis after liver transplantation for chronic hepatitis B- and C-related cirrhosis and hepatocellular carcinoma: a case report with literature review. ( Jia, JD; Rakhda, MI; Wang, TI; Zhao, XY, 2013) |
| "AST, ALT, HCV RNA, and liver fibrosis were determined, and results were compared with a control group of non-treated chronic hepatitis C patients." | 1.40 | Does low-dose prolonged steroid therapy affect the natural history of chronic hepatitis C? ( Artaza Varasa, T; Bárcena Marugán, R; del Campo Terrón, S; Moreno Zamora, A; Romero Gutiérrez, M; Sánchez Ruano, JJ, 2014) |
| "A 57-year old woman with perianal Crohn's disease receiving azathioprine and infliximab developed this type of lymphoma after a short period of time on the treatment." | 1.37 | Plasmablastic lymphoma associated to Crohn's disease and hepatitis C virus chronic infection. ( Aldeguer, M; Arevalo, N; Benito, DM; de Fuenmayor, ML; Foncillas, MA; Plaza, R; Ponferrada, A, 2011) |
| "The chronic hepatitis C-autoimmune hepatitis (AIH) overlap syndrome has been described in the literature, but to date appropriate therapy remains controversial." | 1.32 | Differential efficacy of corticosteroids and interferon in a patient with chronic hepatitis C-autoimmune hepatitis overlap syndrome. ( Dries, V; Goeser, T; Kasper, HU; Petersen-Benz, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 10 (52.63) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| López Couceiro, L | 1 |
| Gómez Domínguez, E | 1 |
| Muñoz Gómez, R | 1 |
| Castellano Tortajada, G | 1 |
| Ibarrola de Andrés, C | 1 |
| Fernández Vázquez, I | 1 |
| Zhao, XY | 1 |
| Rakhda, MI | 1 |
| Wang, TI | 1 |
| Jia, JD | 1 |
| González-Artacho, C | 1 |
| Rodríguez Sicilia, MJ | 1 |
| Alegría-Motte, C | 1 |
| Gómez García, M | 1 |
| Manousou, P | 1 |
| Cholongitas, E | 1 |
| Samonakis, D | 1 |
| Tsochatzis, E | 1 |
| Corbani, A | 1 |
| Dhillon, AP | 1 |
| Davidson, J | 1 |
| Rodríguez-Perálvarez, M | 1 |
| Patch, D | 1 |
| O'Beirne, J | 1 |
| Thorburn, D | 1 |
| Luong, T | 1 |
| Rolles, K | 1 |
| Davidson, B | 1 |
| McCormick, PA | 1 |
| Hayes, P | 1 |
| Burroughs, AK | 1 |
| Romero Gutiérrez, M | 1 |
| del Campo Terrón, S | 1 |
| Moreno Zamora, A | 1 |
| Sánchez Ruano, JJ | 1 |
| Artaza Varasa, T | 1 |
| Bárcena Marugán, R | 1 |
| Lin, KM | 1 |
| Cheng, TT | 1 |
| Lin, JC | 1 |
| Chen, CJ | 1 |
| Magalhães-Costa, P | 1 |
| Lebre, L | 1 |
| Machado, D | 1 |
| Chagas, C | 1 |
| Hsiao, CH | 1 |
| Tseng, KC | 1 |
| Tseng, CW | 1 |
| Tung, CH | 1 |
| Peyrin-Biroulet, L | 1 |
| Cadranel, JF | 1 |
| Nousbaum, JB | 1 |
| Oussalah, A | 1 |
| Seddik, M | 1 |
| Canva, V | 1 |
| Cortot, A | 1 |
| Sogni, P | 1 |
| Gueant, JL | 1 |
| Bigard, MA | 1 |
| Roblin, X | 1 |
| Bronowicki, JP | 1 |
| Chaparro, M | 1 |
| Trapero-Marugán, M | 1 |
| Moreno-Otero, R | 1 |
| Gisbert, JP | 1 |
| Plaza, R | 1 |
| Ponferrada, A | 1 |
| Benito, DM | 1 |
| Arevalo, N | 1 |
| Foncillas, MA | 1 |
| de Fuenmayor, ML | 1 |
| Aldeguer, M | 1 |
| De Vita, S | 1 |
| Quartuccio, L | 1 |
| Isola, M | 1 |
| Mazzaro, C | 1 |
| Scaini, P | 1 |
| Lenzi, M | 1 |
| Campanini, M | 1 |
| Naclerio, C | 1 |
| Tavoni, A | 1 |
| Pietrogrande, M | 1 |
| Ferri, C | 1 |
| Mascia, MT | 1 |
| Masolini, P | 1 |
| Zabotti, A | 1 |
| Maset, M | 1 |
| Roccatello, D | 1 |
| Zignego, AL | 1 |
| Pioltelli, P | 1 |
| Gabrielli, A | 1 |
| Filippini, D | 1 |
| Perrella, O | 1 |
| Migliaresi, S | 1 |
| Galli, M | 1 |
| Bombardieri, S | 1 |
| Monti, G | 1 |
| Petersen-Benz, C | 1 |
| Kasper, HU | 1 |
| Dries, V | 1 |
| Goeser, T | 1 |
| Canet, S | 1 |
| Garrigue, V | 1 |
| Bismuth, J | 1 |
| Chong, G | 1 |
| Lesnik, A | 1 |
| Taourel, P | 1 |
| Mourad, G | 1 |
| Hokari, A | 1 |
| Zeniya, M | 1 |
| Maier, KP | 1 |
| Berenguer, M | 1 |
| Prieto, M | 1 |
| Córdoba, J | 1 |
| Rayón, JM | 1 |
| Carrasco, D | 1 |
| Olaso, V | 1 |
| San-Juan, F | 1 |
| Gobernado, M | 1 |
| Mir, J | 1 |
| Berenguer, J | 1 |
| Nakamura, K | 1 |
| Makino, I | 1 |
| David-Neto, E | 1 |
| Americo da Fonseca, J | 1 |
| Jota de Paula, F | 1 |
| Nahas, WC | 1 |
| Sabbaga, E | 1 |
| Ianhez, LE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Maintenance Treatment by Ribavirin to a Placebo, After an Initial One-year Treatment With Pegylated Interferon-α2a - Ribavirin Association in Hepatitis C Viral Recurrence After Liver Transplantation[NCT00151580] | Phase 3 | 200 participants (Actual) | Interventional | 2002-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for azathioprine and Hepatitis C, Chronic
| Article | Year |
|---|---|
Immunoglobulin G4-associated de novo autoimmune hepatitis after liver transplantation for chronic hepatitis B- and C-related cirrhosis and hepatocellular carcinoma: a case report with literature review.
Topics: Antiviral Agents; Azathioprine; Carcinoma, Hepatocellular; Coinfection; Drug Therapy, Combination; H | 2013 |
[Nocardiosis--is it frequently observed after the introduction of new immunosuppressive agents in renal transplantation?].
Topics: Adrenal Cortex Hormones; Adult; Aged; Antilymphocyte Serum; Azathioprine; Cyclosporine; Diabetes Com | 2004 |
[Difference between autoimmune hepatitis (AIH) with and without hepatitis C virus (HCV)].
Topics: Adrenal Cortex Hormones; Antiviral Agents; Autoantibodies; Azathioprine; Disease Susceptibility; Dru | 2004 |
[Drug therapy in chronic liver disease].
Topics: Adenine; Administration, Oral; Anti-HIV Agents; Antiviral Agents; Azathioprine; Cholangitis, Scleros | 2005 |
[Autoimmune hepatitis: progress in its treatment].
Topics: Azathioprine; Female; Hepatitis C, Chronic; Hepatitis, Autoimmune; Humans; Middle Aged; Prednisolone | 1999 |
3 trials available for azathioprine and Hepatitis C, Chronic
| Article | Year |
|---|---|
Reduced fibrosis in recurrent HCV with tacrolimus, azathioprine and steroids versus tacrolimus: randomised trial long term outcomes.
Topics: Anti-Inflammatory Agents; Azathioprine; Drug Therapy, Combination; Female; Hepatitis C, Chronic; Hum | 2014 |
A randomized controlled trial of rituximab for the treatment of severe cryoglobulinemic vasculitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Murine-Derived; Antiviral Agents | 2012 |
The impact of azathioprine on chronic viral hepatitis in renal transplantation: a long-term, single-center, prospective study on azathioprine withdrawal.
Topics: Adult; Alanine Transaminase; Azathioprine; Bilirubin; Disease Progression; Dose-Response Relationshi | 1999 |
11 other studies available for azathioprine and Hepatitis C, Chronic
| Article | Year |
|---|---|
Healing of autoimmune hepatitis associated with hepatitis C virus infection treated with direct-acting antivirals.
Topics: Antiviral Agents; Azathioprine; Benzimidazoles; Female; Fluorenes; Hepatitis C, Chronic; Hepatitis, | 2019 |
[Outcome of chronic hepatitis B and C in patients with inflammatory bowel disease treated with immunosuppressive drugs and anti-TNF agents].
Topics: Adalimumab; Adenine; Adult; Antibodies, Monoclonal, Humanized; Antiviral Agents; Azathioprine; Crohn | 2014 |
Does low-dose prolonged steroid therapy affect the natural history of chronic hepatitis C?
Topics: Adult; Azathioprine; Cohort Studies; Enzymes; Female; Hepatitis C, Chronic; Humans; Immunosuppressiv | 2014 |
Tumor necrosis factor-α antagonist therapy for concomitant rheumatoid arthritis and hepatitis C virus infection: a case series study.
Topics: Adalimumab; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumato | 2015 |
Lack of impact of hepatitis C virus infection on graft survival after kidney transplantation--a Portuguese single-center experience.
Topics: Adult; Age Factors; Aged; Azathioprine; Cardiovascular Diseases; Case-Control Studies; Cyclosporine; | 2015 |
Late-Onset Immune Thrombocytopenic Purpura After Withdrawal of Interferon Treatment for Chronic Hepatitis C Infection: A Case Report.
Topics: Age of Onset; Antiviral Agents; Azathioprine; Glucocorticoids; Hepatitis C, Chronic; Humans; Immunos | 2015 |
Interaction of ribavirin with azathioprine metabolism potentially induces myelosuppression.
Topics: Adult; Antiviral Agents; Azathioprine; Drug Interactions; Female; Hepatitis C, Chronic; Humans; Immu | 2008 |
Azathioprine plus ribavirin treatment and pancytopenia.
Topics: Adult; Anti-Inflammatory Agents; Antiviral Agents; Azathioprine; Crohn Disease; Drug Interactions; H | 2009 |
Plasmablastic lymphoma associated to Crohn's disease and hepatitis C virus chronic infection.
Topics: Anti-Inflammatory Agents; Antibodies, Monoclonal; Antineoplastic Combined Chemotherapy Protocols; Az | 2011 |
Differential efficacy of corticosteroids and interferon in a patient with chronic hepatitis C-autoimmune hepatitis overlap syndrome.
Topics: Adult; Antiviral Agents; Azathioprine; Drug Therapy, Combination; Female; Glucocorticoids; Haplotype | 2004 |
Early development of chronic active hepatitis in recurrent hepatitis C virus infection after liver transplantation: association with treatment of rejection.
Topics: Alanine Transaminase; Azathioprine; Cyclosporine; Drug Therapy, Combination; Female; Genome, Viral; | 1998 |