azathioprine has been researched along with Hepatic Veno Occlusive Disease in 19 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient with rheumatoid arthritis developed hepatic veno-occlusive disease following the use of azathioprine." | 7.67 | Azathioprine induced hepatic veno-occlusive disease in rheumatoid arthritis. ( DeLacy, LM; Ishak, KG; Lemley, DE; Nashel, DJ; Seeff, LB, 1989) |
| " Azathioprine and monocrotaline were found to be selectively more toxic to SEC than to hepatocytes." | 5.29 | Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease. ( DeLeve, LD; Kaplowitz, N; Kuhlenkamp, JF; Wang, X, 1996) |
| "A patient with rheumatoid arthritis developed hepatic veno-occlusive disease following the use of azathioprine." | 3.67 | Azathioprine induced hepatic veno-occlusive disease in rheumatoid arthritis. ( DeLacy, LM; Ishak, KG; Lemley, DE; Nashel, DJ; Seeff, LB, 1989) |
| "Hepatic sinusoidal obstruction syndrome is frequently linked to high-dose chemotherapy/total-body irradiation in recipients of haematopoietic stem cell transplantation, long-term use of azathioprine after organ transplantation and other chemotherapeutic agents." | 2.43 | Review article: updates in the pathogenesis and therapy of hepatic sinusoidal obstruction syndrome. ( Helmy, A, 2006) |
| " Azathioprine and monocrotaline were found to be selectively more toxic to SEC than to hepatocytes." | 1.29 | Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease. ( DeLeve, LD; Kaplowitz, N; Kuhlenkamp, JF; Wang, X, 1996) |
| "Azathioprine was discontinued." | 1.27 | Hepatic vascular disease after kidney transplantation: report of two cases and review of the literature. ( Adler, M; Cremer, M; De Pauw, L; Delhaye, M; Deprez, C; Gelin, M; Hardy, N; Toussaint, C; Vereerstraeten, P, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (21.05) | 18.7374 |
| 1990's | 8 (42.11) | 18.2507 |
| 2000's | 6 (31.58) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Galeano Valle, F | 1 |
| Muñoz Roldán, I | 1 |
| Donis Sevillano, E | 1 |
| Holtmann, M | 1 |
| Schreiner, O | 1 |
| Köhler, H | 1 |
| Denzer, U | 1 |
| Neurath, M | 1 |
| Galle, PR | 1 |
| Höhler, T | 1 |
| Ben-Ari, Z | 1 |
| Praprotnik, S | 1 |
| Hocevar, A | 1 |
| Ferlan-Marolt, V | 1 |
| Tomsic, M | 1 |
| Helmy, A | 1 |
| de Fontbrune, FS | 1 |
| Mal, H | 1 |
| Dauriat, G | 1 |
| Brugière, O | 1 |
| Biondi, G | 1 |
| Taillé, C | 1 |
| Valla, D | 1 |
| Castier, Y | 1 |
| Fournier, M | 1 |
| Mion, F | 1 |
| Cloix, P | 1 |
| Boillot, O | 1 |
| Gille, D | 1 |
| Bouvier, R | 1 |
| Paliard, P | 1 |
| Berger, F | 1 |
| Dhillon, AP | 1 |
| Burroughs, AK | 1 |
| Hudson, M | 1 |
| Shah, N | 1 |
| Rolles, K | 1 |
| Scheuer, PJ | 1 |
| DeLeve, LD | 1 |
| Wang, X | 1 |
| Kuhlenkamp, JF | 1 |
| Kaplowitz, N | 1 |
| Kohli, HS | 1 |
| Jain, D | 1 |
| Sud, K | 1 |
| Jha, V | 1 |
| Gupta, KL | 1 |
| Sakhuja, V | 1 |
| Joshi, K | 1 |
| Hola, K | 1 |
| Brahm, J | 1 |
| Alvo, M | 1 |
| Cotera, A | 1 |
| Passalacqua, W | 1 |
| Smok, G | 1 |
| Azoulay, D | 1 |
| Castaing, D | 1 |
| Lemoine, A | 1 |
| Samuel, D | 1 |
| Majno, P | 1 |
| Reynes, M | 1 |
| Charpentier, B | 1 |
| Bismuth, H | 1 |
| Böker, KH | 1 |
| Russmann, S | 1 |
| Zimmermann, A | 1 |
| Krähenbühl, S | 1 |
| Kern, B | 1 |
| Reichen, J | 1 |
| Haboubi, NY | 1 |
| Butterworth, D | 1 |
| Ackrill, P | 1 |
| Liaño, F | 1 |
| Moreno, A | 1 |
| Matesanz, R | 1 |
| Teruel, JL | 1 |
| Redondo, C | 1 |
| García-Martín, F | 1 |
| Orte, L | 1 |
| Ortuño, J | 1 |
| Lemley, DE | 1 |
| DeLacy, LM | 1 |
| Seeff, LB | 1 |
| Ishak, KG | 1 |
| Nashel, DJ | 1 |
| Jones, JG | 1 |
| Taylor, DE | 1 |
| Adler, M | 1 |
| Delhaye, M | 1 |
| Deprez, C | 1 |
| Hardy, N | 1 |
| Gelin, M | 1 |
| De Pauw, L | 1 |
| Vereerstraeten, P | 1 |
| Cremer, M | 1 |
| Toussaint, C | 1 |
2 reviews available for azathioprine and Hepatic Veno Occlusive Disease
| Article | Year |
|---|---|
Review article: updates in the pathogenesis and therapy of hepatic sinusoidal obstruction syndrome.
Topics: Animals; Azathioprine; Endothelial Cells; Hematopoietic Stem Cell Transplantation; Heparin; Hepatic | 2006 |
Successful treatment of severe azathioprine-induced hepatic veno-occlusive disease in a kidney-transplanted patient with transjugular intrahepatic portosystemic shunt.
Topics: Adult; Azathioprine; Biopsy; Hepatic Veno-Occlusive Disease; Humans; Immunosuppression Therapy; Immu | 1998 |
17 other studies available for azathioprine and Hepatic Veno Occlusive Disease
| Article | Year |
|---|---|
Azathioprine-induced hepatic sinusoidal obstruction syndrome.
Topics: Adult; Azathioprine; Biopsy; Female; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressive Agent | 2018 |
Veno-occlusive disease (VOD) in Crohn's disease (CD) treated with azathioprine.
Topics: Adult; Azathioprine; Biopsy; Crohn Disease; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressiv | 2003 |
Life-threatening veno-occlusive disease after living-related liver transplantation.
Topics: Azathioprine; Family; Fatal Outcome; Fibrinolytic Agents; Hepatic Veno-Occlusive Disease; Humans; Im | 2003 |
Azathioprine induced hepatic veno-occlusive disease in systemic lupus erythematosus.
Topics: Adult; Azathioprine; Female; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressive Agents; Lupus | 2005 |
Veno-occlusive disease of the liver after lung transplantation.
Topics: Azathioprine; Biopsy; Follow-Up Studies; Graft Rejection; Hepatic Veno-Occlusive Disease; Humans; Im | 2007 |
[Veno-occlusive disease after liver transplantation. Association of acute cellular rejection and toxicity of azathioprine].
Topics: Acute Disease; Azathioprine; Biopsy; Follow-Up Studies; Graft Rejection; Hepatic Veno-Occlusive Dise | 1993 |
Hepatic venular stenosis after orthotopic liver transplantation.
Topics: Adolescent; Adult; Azathioprine; Endothelium, Vascular; Female; Graft Rejection; Hepatic Veno-Occlus | 1994 |
Toxicity of azathioprine and monocrotaline in murine sinusoidal endothelial cells and hepatocytes: the role of glutathione and relevance to hepatic venoocclusive disease.
Topics: Analysis of Variance; Animals; Azathioprine; Buthionine Sulfoximine; Cells, Cultured; Endothelium; E | 1996 |
Azathioprine-induced hepatic veno-occlusive disease in a renal transplant recipient: histological regression following azathioprine withdrawal.
Topics: Azathioprine; Hepatic Veno-Occlusive Disease; Humans; Kidney Transplantation; Liver; Male; Middle Ag | 1996 |
[Hepatic veno-occlusive disease associated to the use of azathioprine in a renal transplant recipient].
Topics: Adult; Azathioprine; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressive Agents; Kidney Failur | 1996 |
[The liver side effects of azathioprine].
Topics: Azathioprine; Hepatic Veno-Occlusive Disease; Humans; Immunosuppressive Agents; Liver; Time Factors | 1999 |
Veno-occlusive disease, nodular regenerative hyperplasia and hepatocellular carcinoma after azathioprine treatment in a patient with ulcerative colitis.
Topics: Aged; Azathioprine; Carcinoma, Hepatocellular; Colitis, Ulcerative; Hepatic Veno-Occlusive Disease; | 2001 |
Does viral hepatitis cause veno-occlusive disease in patients with renal transplants?
Topics: Azathioprine; Hepatic Veno-Occlusive Disease; Hepatitis, Viral, Human; Humans; Kidney Transplantatio | 1990 |
Veno-occlusive hepatic disease of the liver in renal transplantation: is azathioprine the cause?
Topics: Adolescent; Adult; Azathioprine; Child; Female; Hepatic Veno-Occlusive Disease; Hepatitis B; Humans; | 1989 |
Azathioprine induced hepatic veno-occlusive disease in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Azathioprine; Hepatic Veno-Occlusive Disease; Humans; Liver; Male; Middle Age | 1989 |
Hepatic veno-occlusive disease and herbal remedies.
Topics: Azathioprine; Beverages; Hepatic Veno-Occlusive Disease; Humans | 1989 |
Hepatic vascular disease after kidney transplantation: report of two cases and review of the literature.
Topics: Adult; Azathioprine; Biopsy; Chemical and Drug Induced Liver Injury; Hepatic Veins; Hepatic Veno-Occ | 1987 |