Page last updated: 2024-10-23

azathioprine and Hemosiderosis

azathioprine has been researched along with Hemosiderosis in 28 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Hemosiderosis: Conditions in which there is a generalized increase in the iron stores of body tissues, particularly of liver and the MONONUCLEAR PHAGOCYTE SYSTEM, without demonstrable tissue damage. The name refers to the presence of stainable iron in the tissue in the form of hemosiderin.

Research Excerpts

ExcerptRelevanceReference
"Later, patient developed posterior reversible encephalopathy syndrome (PRES)."1.56Idiopathic pulmonary hemosiderosis - A rare cause of chronic anemia. ( Ahmed, R; Butt, A; Iqbal, N; Khan, JA; Khan, O; Rahman, AJ; Sheikh, MDA, 2020)
"Its management in pregnancy is complicated and little clinical data exist on outcomes or treatment."1.32Management of idiopathic pulmonary haemosiderosis in pregnancy: report of two cases. ( Deering, SH; Helman, DL; Hueppchen, NA; Kariya, ST; Shorr, AF; Sullivan, A, 2003)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199013 (46.43)18.7374
1990's3 (10.71)18.2507
2000's4 (14.29)29.6817
2010's5 (17.86)24.3611
2020's3 (10.71)2.80

Authors

AuthorsStudies
Saha, BK2
Noto, T1
Seto, H1
Fukuhara, J1
Murabayashi, M1
Morioka, I1
Butt, A1
Ahmed, R1
Sheikh, MDA1
Khan, O1
Iqbal, N1
Rahman, AJ1
Khan, JA1
Milman, NT1
Pal, P1
De, H1
Giri, PP1
Ganguly, N1
Mandal, A1
Freitas, A1
Senra, V1
Marinho, A1
Guedes, M1
Krumsiek, A1
Poggemann, V1
Wertzel, H1
Achenbach, HJ1
Persson, HL1
Vainikka, LK1
Eriksson, HB1
Wennerström, U1
STEINER, B3
NABRADY, J2
Helman, DL1
Sullivan, A1
Kariya, ST1
Deering, SH1
Hueppchen, NA1
Shorr, AF1
Gaziev, J1
Sodani, P1
Polchi, P1
Andreani, M1
Lucarelli, G1
Willms, H1
Gutjahr, K1
Juergens, UR1
Hammerschmidt, S1
Gessner, C1
Hoheisel, G1
Wirtz, H1
Gillissen, A1
Marwaha, RK1
Garewal, G1
Kumar, V1
Sarkar, B1
Malik, N1
Sawiełajc, K1
Kruś, J1
Balcar-Boroń, A1
Airaghi, L1
Ciceri, L1
Giannini, S1
Ferrero, S1
Meroni, PL1
Tedeschi, A1
Yeager, H1
Powell, D1
Weinberg, RM1
Bauer, H1
Bellanti, JA1
Katz, S1
Rossi, GA1
Balzano, E1
Battistini, E1
Oddera, S1
Marchese, P1
Acquila, M1
Fregonese, B1
Mori, PG1
Le Maire, PA1
Kamińska, M1
Piotrowicz, E1
Ratajczak, B1
Boj, E1
Byrd, RB1
Gracey, DR1
Cerruti Mainardi, P1
Massimo, L1
Mutz, I1
Schröfl, P1
Miolin, A1
Radojicić, B1
Steiger, RP1
Lane, DJ1
Hamilton, WS1
Guisan, M1
Bircher, J1
Kistler, HJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Sun Yat-sen Memorial Hospital[NCT02985346]Early Phase 1100 participants (Anticipated)Interventional2017-01-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for azathioprine and Hemosiderosis

ArticleYear
Idiopathic pulmonary hemosiderosis: a review of the treatments used during the past 30 years and future directions.
    Clinical rheumatology, 2021, Volume: 40, Issue:7

    Topics: Adult; Azathioprine; Hemoptysis; Hemosiderosis; Hemosiderosis, Pulmonary; Humans; Lung Diseases

2021

Other Studies

27 other studies available for azathioprine and Hemosiderosis

ArticleYear
Determining the threshold for azathioprine use in recurrent diffuse alveolar hemorrhage in idiopathic pulmonary hemosiderosis.
    The American journal of the medical sciences, 2023, Volume: 366, Issue:2

    Topics: Azathioprine; Hemorrhage; Hemosiderosis; Humans; Lung Diseases

2023
Early diagnosis of idiopathic pulmonary hemosiderosis using gastric lavage.
    Pediatrics international : official journal of the Japan Pediatric Society, 2019, Volume: 61, Issue:12

    Topics: Azathioprine; Early Diagnosis; Gastric Lavage; Hemosiderosis; Hemosiderosis, Pulmonary; Humans; Immu

2019
Idiopathic pulmonary hemosiderosis - A rare cause of chronic anemia.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2020, Jun-09, Volume: 90, Issue:2

    Topics: Adult; Anemia; Azathioprine; Biopsy; Bronchoscopy; Child; Chronic Disease; Drug Therapy, Combination

2020
Early Initiation of Steroid-sparing Drugs in Idiopathic Pulmonary Hemosiderosis.
    Indian pediatrics, 2019, 01-15, Volume: 56, Issue:1

    Topics: Azathioprine; Child; Hemosiderosis; Hemosiderosis, Pulmonary; Humans; Hydroxychloroquine; Immunosupp

2019
Chronic alveolar haemorrhage in a paediatric patient: a diagnostic and treatment challenge.
    BMJ case reports, 2015, Apr-21, Volume: 2015

    Topics: Adolescent; Adrenal Cortex Hormones; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Biopsy; C

2015
[Recurrent hemoptysis in a 29-year old woman].
    Der Internist, 2010, Volume: 51, Issue:12

    Topics: Adult; Anemia; Anti-Inflammatory Agents; Azathioprine; Biopsy; Bronchoscopy; Combined Modality Thera

2010
Lane-Hamilton syndrome: ferritin protects lung macrophages against iron and oxidation.
    Chest, 2011, Volume: 139, Issue:2

    Topics: Adult; Animals; Apoferritins; Apoptosis; Azathioprine; Blotting, Western; Combined Modality Therapy;

2011
[IMMUNOALLERGIC PULMONARY HEMORRHAGE TREATED WITH IMURAN. (PRELIMINARY REPORT)].
    Orvosi hetilap, 1964, Dec-06, Volume: 105

    Topics: Adolescent; Antineoplastic Agents; Azathioprine; Dexamethasone; Drug Therapy; Hemoptysis; Hemorrhage

1964
Management of idiopathic pulmonary haemosiderosis in pregnancy: report of two cases.
    Respirology (Carlton, Vic.), 2003, Volume: 8, Issue:3

    Topics: Adult; Aspergillosis; Azathioprine; Fatal Outcome; Female; Glucocorticoids; Hemosiderosis; Humans; I

2003
Bone marrow transplantation in adults with thalassemia: Treatment and long-term follow-up.
    Annals of the New York Academy of Sciences, 2005, Volume: 1054

    Topics: Adolescent; Adult; Azathioprine; Bone Marrow Transplantation; Busulfan; Chelation Therapy; Clinical

2005
[Diagnostics and therapy of idiopathic pulmonary hemosiderosis].
    Medizinische Klinik (Munich, Germany : 1983), 2007, Jun-15, Volume: 102, Issue:6

    Topics: Adult; Anemia, Iron-Deficiency; Azathioprine; Biopsy; Bronchoscopy; Diagnosis, Differential; Hemopty

2007
Microcytic hypochromic anemia in idiopathic pulmonary hemosiderosis: a diagnostic pitfall.
    Indian pediatrics, 1994, Volume: 31, Issue:9

    Topics: Anemia, Hypochromic; Azathioprine; Child; Child, Preschool; Diagnosis, Differential; Fatal Outcome;

1994
[Spontaneous pulmonary hemosiderosis in a 4-year old boy].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1994, Volume: 47, Issue:5-6

    Topics: Azathioprine; Child, Preschool; Drug Therapy, Combination; Ethamsylate; Follow-Up Studies; Hemosider

1994
Idiopathic pulmonary hemosiderosis in an adult. Favourable response to azathioprine.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2001, Volume: 56, Issue:3

    Topics: Adult; Azathioprine; Biopsy, Needle; Female; Follow-Up Studies; Hemoptysis; Hemosiderosis; Humans; L

2001
Idiopathic pulmonary hemosiderosis: ultrastructural studies and responses to azathioprine.
    Archives of internal medicine, 1976, Volume: 136, Issue:10

    Topics: Anemia, Hypochromic; Azathioprine; Child; Dose-Response Relationship, Drug; Hemosiderosis; Humans; L

1976
Long-term prednisone and azathioprine treatment of a patient with idiopathic pulmonary hemosiderosis.
    Pediatric pulmonology, 1992, Volume: 13, Issue:3

    Topics: Azathioprine; Bronchoalveolar Lavage Fluid; Child; Female; Forced Expiratory Volume; Hemosiderosis;

1992
Immunoallergic lung purpura treated with azathioprine.
    Lancet (London, England), 1965, Jan-16, Volume: 1, Issue:7377

    Topics: Adolescent; Azathioprine; Dexamethasone; Hemosiderosis; Humans; Lung Diseases; Male; Prednisolone; P

1965
[Idiopathic pulmonary hemosiderosis. Description of 3 patients and a review of the literature].
    Maandschrift voor kindergeneeskunde, 1973, Volume: 41, Issue:1

    Topics: Adolescent; Azathioprine; Blood Transfusion; Child; Child, Preschool; Diet; Female; Hemosiderosis; H

1973
[Treatment of idiopathic pulmonary hemosiderosis with immunosuppressive agents].
    Pediatria polska, 1973, Volume: 48, Issue:6

    Topics: Azathioprine; Child, Preschool; Cyclophosphamide; Hemosiderosis; Humans; Immunosuppressive Agents; L

1973
Immunosuppressive treatment of idiopathic pulmonary hemosiderosis.
    JAMA, 1973, Oct-22, Volume: 226, Issue:4

    Topics: Adult; Azathioprine; Hemoptysis; Hemosiderosis; Humans; Immunosuppression Therapy; Lung Diseases; Ma

1973
[Nosological classification and new therapeutic trends in idiopathic pulmonary hemosiderosis].
    Minerva pediatrica, 1966, Dec-15, Volume: 18, Issue:39

    Topics: Adrenal Cortex Hormones; Azathioprine; Blood Protein Electrophoresis; Child, Preschool; Deferoxamine

1966
[Therapy of idiopathic pulmonary hemosiderosis].
    Wiener klinische Wochenschrift, 1971, Dec-10, Volume: 83, Issue:49

    Topics: Adolescent; Azathioprine; Female; Hemosiderosis; Humans; Iron; Lung Diseases; Male; Myocarditis; Pre

1971
[Idiopathic pulmonary siderosis successfully treated by imuran].
    Acta medica Iugoslavica, 1970, Volume: 24, Issue:1

    Topics: Adolescent; Azathioprine; Child; Female; Hemosiderosis; Humans; Lung Diseases; Male

1970
[Etiology and therapy of idiopathic lung hemosideroses].
    Helvetica medica acta. Supplementum, 1966, May-15, Volume: 46

    Topics: Adult; Azathioprine; Cortisone; Female; Hematuria; Hemosiderosis; Humans; Iron; Lung Diseases; Pulmo

1966
Idiopathic steatorrhoea and idiopathic pulmonary haemosiderosis.
    British medical journal, 1971, Apr-10, Volume: 2, Issue:5753

    Topics: Adult; Azathioprine; Celiac Disease; Folic Acid Deficiency; Hemoglobinometry; Hemoptysis; Hemosidero

1971
Immunoallergic lung purpura treated with azathioprine and with splenectomy and azathioprine.
    Helvetica paediatrica acta, 1969, Volume: 24, Issue:4

    Topics: Adolescent; Autoimmune Diseases; Azathioprine; Child; Child, Preschool; Hemosiderosis; Humans; Lung

1969
[Apropos of differential diagnosis of pulmonary hemosiderosis].
    Schweizerische medizinische Wochenschrift, 1966, Oct-29, Volume: 96, Issue:43

    Topics: Adult; Anemia, Hypochromic; Anti-Glomerular Basement Membrane Disease; Azathioprine; Diagnosis, Diff

1966