Page last updated: 2024-10-23

azathioprine and Hemophilia A

azathioprine has been researched along with Hemophilia A in 15 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Hemophilia A: The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.

Research Excerpts

ExcerptRelevanceReference
"Acquired hemophilia A (AH) is a rare and serious acquired bleeding disorder where prompt and correct diagnosis is crucial, and immune suppression is often required for factor VIII (FVIII) autoantibody eradication."2.45Twelve years of experience of acquired hemophilia A: trials and tribulations in South Australia. ( Al-Qunfoidi, R; Coghlan, D; Duncan, E; Jaksic, W; Lloyd, J; McRae, S; Singhal, D; Szabo, F; Tay, L, 2009)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199011 (73.33)18.7374
1990's1 (6.67)18.2507
2000's2 (13.33)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Christiansen, J1
Kahn, R1
Schmidtchen, A1
Berggård, K1
Tay, L1
Duncan, E1
Singhal, D1
Al-Qunfoidi, R1
Coghlan, D1
Jaksic, W1
Szabo, F1
McRae, S1
Lloyd, J1
Söhngen, D1
Specker, C1
Bach, D1
Kuntz, BM1
Burk, M1
Aul, C1
Kobbe, G1
Heyll, A1
Hollmig, KA1
Schneider, W1
Hall, RL1
Leahy, MF1
Rubin, R1
Niemetz, J1
Estren, S1
Green, D2
Peacock, EE1
Webster, WP2
Penick, GD1
Madden, JW1
Hutchin, P2
Norman, JC2
Covelli, VH2
Sise, HS2
Groth, CG1
Hathaway, WE1
Gustafsson, A1
Geis, WP1
Putnam, CW1
Björkén, C1
Porter, KA1
Starzl, TE1
Marchioro, TL2
Hougie, C2
Ragde, H2
Epstein, RB2
Thomas, ED2
Zukoski, CF1
Penick, G1
McKee, PA1
Coussons, RT1
Buckner, RG1
Williams, GR1
Hampton, JW1

Reviews

1 review available for azathioprine and Hemophilia A

ArticleYear
Twelve years of experience of acquired hemophilia A: trials and tribulations in South Australia.
    Seminars in thrombosis and hemostasis, 2009, Volume: 35, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Auto

2009

Other Studies

14 other studies available for azathioprine and Hemophilia A

ArticleYear
Idiopathic angioedema and urticarial vasculitis in a patient with a history of acquired haemophilia.
    Acta dermato-venereologica, 2015, Volume: 95, Issue:2

    Topics: Aged; Angioedema; Autoimmunity; Azathioprine; Colchicine; Dapsone; Drug Therapy, Combination; Hemoph

2015
Acquired factor VIII inhibitors in nonhemophilic patients.
    Annals of hematology, 1997, Volume: 74, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies; Asthma; Azathioprine; Cytomegalovirus Infections; Factor

1997
Acquired Factor VIII autoantibody: four cases demonstrating the heterogenous nature of this condition and problems involved in diagnosis and treatment.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; Azathiop

2001
Use of animal AHG concentrates (factor VIII) in the treatment of life-threatening hemorrhage in patients with factor VIII antibodies.
    Annals of the New York Academy of Sciences, 1975, Jan-20, Volume: 240

    Topics: Airway Obstruction; Animals; Antibodies; Anticoagulants; Azathioprine; Blood Transfusion; Cattle; Cy

1975
Factor VIII antibodies: immunosuppressive therapy.
    Annals of the New York Academy of Sciences, 1975, Jan-20, Volume: 240

    Topics: Aged; Animals; Antibodies; Antibody Formation; Anticoagulants; Azathioprine; Blood Transfusion; Catt

1975
Transplantation of the spleen.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Animals; Antilymphocyte Serum; Aortography; Azathioprine; Dactinomycin; Dogs; Epinephrine; Factor VI

1969
Transplantation of the spleen: experimental cure of hemophilia.
    Surgery, 1968, Volume: 64, Issue:1

    Topics: Adolescent; Adult; Animals; Antibodies, Anti-Idiotypic; Azathioprine; Blood Group Antigens; Chemical

1968
Experimental transplantation of the spleen for classical hemophilia A. Rationales and long-term results.
    Bibliotheca haematologica, 1970, Volume: 34

    Topics: Animals; Azathioprine; Blood Coagulation Tests; Dogs; Epinephrine; Factor VIII; Graft vs Host Reacti

1970
Correction of coagulation in the hemophilic dog by transplantation of lymphatic tissue.
    Surgery, 1974, Volume: 75, Issue:5

    Topics: Animals; Antilymphocyte Serum; Azathioprine; Blood Coagulation; Blood Vessels; Dogs; Factor VIII; Fe

1974
Hemophilia: role of organ homografts.
    Science (New York, N.Y.), 1969, Jan-10, Volume: 163, Issue:3863

    Topics: Animals; Azathioprine; Blood Coagulation Tests; Bone Marrow Transplantation; Dogs; Factor VIII; Hemo

1969
Synthesis and control of antihemophilic globulin (plasma factor 8).
    Surgical forum, 1970, Volume: 21

    Topics: Animals; Azathioprine; Blood Coagulation Tests; Dogs; Factor VIII; Fibrinogen; Hemophilia A; Kidney;

1970
Organ homografts for hemophilia.
    Transplantation proceedings, 1969, Volume: 1, Issue:1

    Topics: Animals; Azathioprine; Dogs; Factor VIII; Hemophilia A; Histocompatibility Testing; Hyperbilirubinem

1969
Therapeutic use of factor VIII.
    The New England journal of medicine, 1972, Oct-19, Volume: 287, Issue:16

    Topics: Aged; Azathioprine; Factor VIII; Hemophilia A; Humans; Male

1972
Effects of the spleen on canine factor VIII levels.
    The Journal of laboratory and clinical medicine, 1970, Volume: 75, Issue:3

    Topics: Animals; Azathioprine; Blood Coagulation; Dogs; Factor VIII; Hemophilia A; Homeostasis; Intestine, S

1970