azathioprine has been researched along with Hemolysis in 18 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hemolysis: The destruction of ERYTHROCYTES by many different causal agents such as antibodies, bacteria, chemicals, temperature, and changes in tonicity.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To determine adverse events of ribavirin in the treatment of chronic hepatitis C, 41 patients (18 with cirrhosis), treated with ribavirin at an initial dose of 600-1200mg day(-1), were analysed retrospectively (six patients were treated twice because adverse effects during the first treatment necessitated cessation of ribavirin)." | 7.69 | Effects of cirrhosis, interferon and azathioprine on adverse events in patients with chronic hepatitis C treated with ribavirin. ( Blot, C; Mathurin, P; Moussalli, J; Opolon, P; Perrin, M; Plassart, F; Poynard, T; Thevenot, T, 1997) |
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 7.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| " Previously, multiple courses of glucocorticoids, rituximab, azathioprine, mycophenolate mofetil, cyclophosphamide, bortezomib, and a splenectomy failed to stop or stabilize hemoglobin levels and hemolysis." | 4.31 | Abatacept as salvage therapy for life-threatening refractory autoimmune hemolytic anemia: a case report. ( Hoffmann, J; Neubauer, A; Schliesser, G, 2023) |
| " Prednisone and azathioprine administration improved the liver disease but failed to control hemolysis so that repeated blood transfusions were necessary." | 3.69 | [Giant cell hepatitis and autoimmune hemolytic anemia: efficacy of splenectomy on hemolysis]. ( Choulot, JJ; Etcharry, F; Mensire, A; Parent, Y; Saint-Martin, J, 1996) |
| "To determine adverse events of ribavirin in the treatment of chronic hepatitis C, 41 patients (18 with cirrhosis), treated with ribavirin at an initial dose of 600-1200mg day(-1), were analysed retrospectively (six patients were treated twice because adverse effects during the first treatment necessitated cessation of ribavirin)." | 3.69 | Effects of cirrhosis, interferon and azathioprine on adverse events in patients with chronic hepatitis C treated with ribavirin. ( Blot, C; Mathurin, P; Moussalli, J; Opolon, P; Perrin, M; Plassart, F; Poynard, T; Thevenot, T, 1997) |
| " Chlorambucil may hold advantages over the immunosuppressive drugs normally recommended in this condition, azathioprine and cyclophosphamide, as it appears less liable to cause important marrow suppression and, unlike cyclophosphamide is not associated with alopecia and haemorrhagic cystitis." | 3.65 | Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil. ( Dunnill, MS; Halley, W; Holt, JM; Oliver, DO; Snaith, ML; Stephenson, AC, 1973) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (66.67) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hoffmann, J | 1 |
| Schliesser, G | 1 |
| Neubauer, A | 1 |
| Mannari, D | 1 |
| Liu, C | 1 |
| Hughes, D | 1 |
| Mehta, A | 1 |
| Lundgren, G | 1 |
| Asaba, H | 1 |
| Bergström, J | 1 |
| Groth, CG | 2 |
| Magnusson, G | 1 |
| Möller, E | 1 |
| Strindberg, J | 1 |
| Wehle, B | 1 |
| Svorcová, M | 1 |
| Rezábek, K | 1 |
| Semonský, M | 1 |
| Martínez-Rueda, JO | 1 |
| Arce-Salinas, CA | 1 |
| Kraus, A | 1 |
| Alcocer-Varela, J | 1 |
| Alarcón-Segovia, D | 1 |
| Choulot, JJ | 1 |
| Parent, Y | 1 |
| Etcharry, F | 1 |
| Saint-Martin, J | 1 |
| Mensire, A | 1 |
| Thevenot, T | 1 |
| Mathurin, P | 1 |
| Moussalli, J | 1 |
| Perrin, M | 1 |
| Plassart, F | 1 |
| Blot, C | 1 |
| Opolon, P | 1 |
| Poynard, T | 1 |
| Purves, EC | 1 |
| Overgaard, K | 1 |
| Werdelin, L | 1 |
| Sørensen, H | 1 |
| Mogensen, P | 1 |
| Boysen, G | 1 |
| Greif, J | 1 |
| Erdmann, E | 1 |
| Ala, FA | 1 |
| Shearman, DJ | 1 |
| Müller, US | 2 |
| Wirth, W | 2 |
| Thöne, F | 2 |
| Junge-Hülsing, G | 2 |
| Hauss, WH | 1 |
| Benfield, JR | 1 |
| Beall, GN | 1 |
| Gondos, B | 1 |
| Peter, ME | 1 |
| Shimada, K | 1 |
| Schick, P | 1 |
| Mizumoto, R | 1 |
| Yokota, T | 1 |
| OSAWA, J | 1 |
| Kono, A | 1 |
| OTOSHI, E | 1 |
| Torisu, M | 1 |
| Yokoyama, T | 1 |
| Kohler, PF | 1 |
| Durst, AL | 1 |
| Martineau, G | 1 |
| Schroter, G | 1 |
| Amemiya, H | 1 |
| Starzl, TE | 1 |
| Pisano, JC | 1 |
| Patterson, JT | 1 |
| Di Luzio, NR | 1 |
| Snaith, ML | 1 |
| Holt, JM | 1 |
| Oliver, DO | 1 |
| Dunnill, MS | 1 |
| Halley, W | 1 |
| Stephenson, AC | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Amyotrophic Lateral Sclerosis and the Innate Immune System[NCT02869048] | 375 participants (Anticipated) | Observational | 2016-06-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
18 other studies available for azathioprine and Hemolysis
| Article | Year |
|---|---|
Abatacept as salvage therapy for life-threatening refractory autoimmune hemolytic anemia: a case report.
Topics: Abatacept; Anemia, Hemolytic, Autoimmune; Azathioprine; CTLA-4 Antigen; Cyclosporins; Female; Glucoc | 2023 |
The role of heparin in alleviating complement-mediated acute intravascular haemolysis.
Topics: 3' Untranslated Regions; Acute Disease; Adult; Anemia, Hemolytic, Autoimmune; Azathioprine; Combined | 2008 |
Fulminating anti-A autoimmune hemolysis with anuria in a renal transplant recipient: a therapeutic role of plasma exchange.
Topics: Acute Kidney Injury; Adult; Antilymphocyte Serum; Anuria; Autoimmune Diseases; Azathioprine; Female; | 1981 |
Effect of azathioprine on antibody formation in mice and its modification by delta-(2-amino-6-hydroxy-3,4-dihydro-4-oxo-5-pyrimidinyl)-valeric acid.
Topics: Animals; Antibody Formation; Azathioprine; Drug Interactions; Female; Hemagglutination Tests; Hemoly | 1980 |
Factors associated with fetal losses in severe systemic lupus erythematosus.
Topics: Adult; Analysis of Variance; Azathioprine; Case-Control Studies; Chloroquine; Cohort Studies; Congen | 1996 |
[Giant cell hepatitis and autoimmune hemolytic anemia: efficacy of splenectomy on hemolysis].
Topics: Anemia, Hemolytic, Autoimmune; Azathioprine; Combined Modality Therapy; Drug Therapy, Combination; H | 1996 |
Effects of cirrhosis, interferon and azathioprine on adverse events in patients with chronic hepatitis C treated with ribavirin.
Topics: Adult; Aged; Anemia; Antiviral Agents; Azathioprine; Chronic Disease; Contraindications; Drug Therap | 1997 |
Mechanisms of specific and non-specific tumour immunity after azathioprine treatment of mice.
Topics: Animals; Antibodies, Neoplasm; Antibody Formation; Azathioprine; Cytotoxicity Tests, Immunologic; Do | 1975 |
Cytotoxic activity in plasma from patients with amyotrophic lateral sclerosis.
Topics: Aged; Aged, 80 and over; Amyotrophic Lateral Sclerosis; Azathioprine; Female; Hemolysis; Humans; Mal | 1991 |
[Life-threatening interaction between azathioprine and allopurinol].
Topics: Allopurinol; Azathioprine; Chemical and Drug Induced Liver Injury; Drug Synergism; Drug Therapy, Com | 1985 |
A case of autoimmune haemolytic anaemia, thrombocytopenia and Landry-Guillain-Barré syndrome.
Topics: Adult; Anemia, Hemolytic, Autoimmune; Antitubercular Agents; Azathioprine; Blood Sedimentation; Cere | 1965 |
[Animal experiments on the anti-inflammatory and immunosuppressive effect of cytostatic agents].
Topics: Animals; Anti-Inflammatory Agents; Azathioprine; Cyclic P-Oxides; Cyclophosphamide; Dose-Response Re | 1973 |
Serial observations on immunologically matched lung allografts.
Topics: Animals; Azathioprine; Biopsy; Bronchoscopy; Bronchospirometry; Complement System Proteins; Cytotoxi | 1972 |
Orthotopic partial hepatic transplantation in dogs.
Topics: Animals; Azathioprine; Dogs; Female; Hemodynamics; Hemolysis; Hepatectomy; Hepatic Veins; Liver; Liv | 1974 |
Serum complement after orthotopic transplantation of the human liver.
Topics: Adolescent; Adult; Azathioprine; Cholestasis; Chronic Disease; Complement System Proteins; Graft Rej | 1972 |
Reticuloendothelial function in immune-suppressed animals.
Topics: Amino Acids; Animals; Antilymphocyte Serum; Antineoplastic Agents; Azathioprine; Carbon; Colloids; C | 1972 |
Treatment of patients with systemic lupus erythematosus including nephritis with chlorambucil.
Topics: Adult; Alopecia; Amenorrhea; Azathioprine; Biopsy; Bone Marrow; Chlorambucil; Cyclophosphamide; Cyst | 1973 |
[Effects of immunosuppressive agents and cytostatics on connective tissue metabolism and antibody production].
Topics: Animals; Antibody Formation; Azathioprine; Connective Tissue; Cyclophosphamide; Granulation Tissue; | 1972 |