Page last updated: 2024-10-23

azathioprine and Hematuria

azathioprine has been researched along with Hematuria in 32 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Hematuria: Presence of blood in the urine.

Research Excerpts

ExcerptRelevanceReference
"Thirty-eight patients with diffuse glomerulonephritis of systemic lupus erythematosus were randomly assigned to add cyclophosphamide, azathioprine, or nothing to low-dose corticosteroid treatment and have been followed for a mean of 21/3 years thereafter."9.04Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months. ( Decker, JL; Klippel, JH; Plotz, PH; Steinberg, AD, 1975)
"To establish the profile of patients with renal involvement due to IgA vasculitisand to describe our experience with the use of azathioprine to treat patients with nephritis."7.91The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment? ( Andrade, MC; Clemente, G; Fernandez, JD; Fraga, MM; Len, CA; Schinzel, V; Terreri, MT, 2019)
"Thirty-eight patients with diffuse glomerulonephritis of systemic lupus erythematosus were randomly assigned to add cyclophosphamide, azathioprine, or nothing to low-dose corticosteroid treatment and have been followed for a mean of 21/3 years thereafter."5.04Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months. ( Decker, JL; Klippel, JH; Plotz, PH; Steinberg, AD, 1975)
"To establish the profile of patients with renal involvement due to IgA vasculitisand to describe our experience with the use of azathioprine to treat patients with nephritis."3.91The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment? ( Andrade, MC; Clemente, G; Fernandez, JD; Fraga, MM; Len, CA; Schinzel, V; Terreri, MT, 2019)
"Treatment with prednisolone, azathioprine, heparin-warfarin, and dipyridamole early in the course of disease may prevent immunologic renal injury in children with severe IgA nephropathy."2.69A controlled trial of combined therapy for newly diagnosed severe childhood IgA nephropathy. The Japanese Pediatric IgA Nephropathy Treatment Study Group. ( Awazu, M; Hattori, S; Honda, M; Iitaka, K; Ito, H; Ito, K; Koitabashi, Y; Matsuyama, S; Nakagawa, K; Nakamura, H; Ninomiya, M; Sakai, T; Seino, Y; Takeda, N; Takekoshi, Y; Yamaoka, K; Yoshikawa, N, 1999)
"Recto-urethral fistulas due to Crohn's disease are very uncommon."1.35[Urethral fistula due to Crohn's disease: case report of successful conservative management]. ( Borovicka, J; Engeler, DS; Hetzer, FH; Meyer, D; Schmid, HP; Schwab, C, 2008)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199023 (71.88)18.7374
1990's3 (9.38)18.2507
2000's3 (9.38)29.6817
2010's3 (9.38)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schinzel, V1
Fernandez, JD1
Clemente, G1
Fraga, MM1
Andrade, MC1
Len, CA1
Terreri, MT1
Bui, T1
Chandrakasan, S1
Poulik, J1
Fathalla, BM1
Sokumbi, O1
Wetter, DA1
Makol, A1
Warrington, KJ1
Brunner, A1
Tzankov, A1
Akkad, T1
Lhotta, K1
Bartsch, G1
Mikuz, G1
Radhakrishnan, KR1
Kay, M1
Wyllie, R1
Hashkes, PJ1
Schwab, C1
Meyer, D1
Hetzer, FH1
Borovicka, J1
Schmid, HP1
Engeler, DS1
Wahn, V1
Göbel, U1
Ebell, W1
Jürgens, H1
Bergstein, J1
Leiser, J1
Andreoli, SP1
Yoshikawa, N1
Ito, H1
Sakai, T1
Takekoshi, Y1
Honda, M1
Awazu, M1
Ito, K1
Iitaka, K1
Koitabashi, Y1
Yamaoka, K1
Nakagawa, K1
Nakamura, H1
Matsuyama, S1
Seino, Y1
Takeda, N1
Hattori, S1
Ninomiya, M1
Decker, JL1
Klippel, JH1
Plotz, PH1
Steinberg, AD1
Jardim, HM1
Leake, J1
Risdon, RA1
Barratt, TM1
Dillon, MJ1
Lim, R1
Parker, JL1
Cameron, JS2
Glasgow, EF3
Ogg, CS2
White, RH3
Busch, GJ1
Galvanek, EG1
Reynolds, ES1
Diekmann, L1
Hüther, W1
Manitz, G1
Mönninghoff, W1
McIntosh, RM1
Griswold, W1
Smith, FG1
Kaufman, DB1
Urizar, R1
Vernier, RL1
Mills, RJ1
Forbes, MJ1
Sinclair, L1
Meadow, SR1
Moncrieff, MW1
Kampf, D1
Baethke, R1
Evans, DB1
Calne, RY1
Gömöri, P1
Beregi, E1
Varga, S1
Nanra, RS1
Kincaid-Smith, P1
Makker, SP1
Heymann, W1
Fries, D1
Bruna-Blanc, N1
Banssillon, V1
Zech, P1
Touboul, P1
Canarelli, G1
Traeger, J1
Hansson, L1
Berglund, G1
Vikgren, P1
Brass, H1
Lapp, H1
Heintz, R1
Nebe, H1
Steiger, RP1
Zollinger, HU1
Gaboardi, F1
Kämpfen, P1
Hodler, J1
Mehls, O1
Schärer, K1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase IV Open Label Uncontrolled Trial of the Dual Blockade of the Renin Angiotensin System With Enalapril Plus Valsartan Combined With Oral Methylprednisolone for the Treatment of Proteinuria in IGA Nephropathy[NCT00367562]Phase 420 participants Interventional1996-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for azathioprine and Hematuria

ArticleYear
[Therapy of glomerulonephritis with corticosteroids and immunosuppressive agents].
    Deutsche medizinische Wochenschrift (1946), 1974, May-24, Volume: 99, Issue:21

    Topics: Adrenal Cortex Hormones; Adult; Amyloidosis; Azathioprine; Child; Cyclophosphamide; Diabetic Nephrop

1974

Trials

3 trials available for azathioprine and Hematuria

ArticleYear
Response of crescentic Henoch-Schoenlein purpura nephritis to corticosteroid and azathioprine therapy.
    Clinical nephrology, 1998, Volume: 49, Issue:1

    Topics: Adolescent; Azathioprine; Child; Child, Preschool; Creatinine; Drug Therapy, Combination; Female; Gl

1998
A controlled trial of combined therapy for newly diagnosed severe childhood IgA nephropathy. The Japanese Pediatric IgA Nephropathy Treatment Study Group.
    Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:1

    Topics: Adolescent; Azathioprine; Blood Urea Nitrogen; Child; Dipyridamole; Drug Therapy, Combination; Glome

1999
Cyclophosphamide or azathioprine in lupus glomerulonephritis. A controlled trial: results at 28 months.
    Annals of internal medicine, 1975, Volume: 83, Issue:5

    Topics: Adolescent; Adult; Amenorrhea; Azathioprine; Child; Clinical Trials as Topic; Complement C3; Cycloph

1975

Other Studies

28 other studies available for azathioprine and Hematuria

ArticleYear
The profile and clinical outcomes of patients with renal involvement due to IgA vasculitis: is azathioprine a good option for treatment?
    Advances in rheumatology (London, England), 2019, 05-22, Volume: 59, Issue:1

    Topics: Adolescent; Antirheumatic Agents; Azathioprine; Child; Child, Preschool; Cyclophosphamide; Female; H

2019
Granulomatosis with polyangiitis presenting as Henoch-Schönlein purpura in children.
    Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases, 2013, Volume: 19, Issue:4

    Topics: Abdominal Pain; Anti-Infective Agents; Antibodies, Antineutrophil Cytoplasmic; Azathioprine; Child;

2013
Vasculitis associated with tumor necrosis factor-α inhibitors.
    Mayo Clinic proceedings, 2012, Volume: 87, Issue:8

    Topics: Adalimumab; Adult; Aged; Anti-Inflammatory Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, H

2012
Wegener's granulomatosis presenting with gross hematuria due to prostatitis.
    Virchows Archiv : an international journal of pathology, 2004, Volume: 444, Issue:1

    Topics: Azathioprine; Biopsy; Granulomatosis with Polyangiitis; Hematuria; Humans; Immunosuppressive Agents;

2004
Wegener granulomatosis mimicking inflammatory bowel disease in a pediatric patient.
    Journal of pediatric gastroenterology and nutrition, 2006, Volume: 43, Issue:3

    Topics: Abdominal Pain; Adolescent; Antibodies, Antineutrophil Cytoplasmic; Appendectomy; Azathioprine; Biop

2006
[Urethral fistula due to Crohn's disease: case report of successful conservative management].
    Der Urologe. Ausg. A, 2008, Volume: 47, Issue:10

    Topics: Azathioprine; Ciprofloxacin; Crohn Disease; Cystoscopy; Cystostomy; Diagnosis, Differential; Drug Th

2008
[Therapy of acute pulmonary hemorrhage in systemic lupus erythematosus].
    MMW, Munchener medizinische Wochenschrift, 1980, Mar-21, Volume: 122, Issue:12

    Topics: Azathioprine; Child; Hematuria; Hemorrhage; Humans; Lung; Lupus Erythematosus, Systemic; Male; Predn

1980
Crescentic glomerulonephritis in children.
    Pediatric nephrology (Berlin, Germany), 1992, Volume: 6, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Anticoagulants; Azathioprine; Child; Child, Preschool; Cyclopho

1992
Apparent haematuria: an early sign in polymyositis.
    British medical journal (Clinical research ed.), 1988, Jun-18, Volume: 296, Issue:6638

    Topics: Adult; Azathioprine; Cyclophosphamide; Dermatomyositis; Drug Therapy, Combination; Hematuria; Humans

1988
Membranoproliferative glomerulonephritis and persistent hypocomplementaemia.
    British medical journal, 1970, Oct-03, Volume: 4, Issue:5726

    Topics: Adolescent; Adult; Azathioprine; Beta-Globulins; Blood Protein Disorders; Child; Child, Preschool; C

1970
Human renal allografts. Analysis of lesions in long-term survivors.
    Human pathology, 1971, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Arteries; Azaserine; Azathioprine; Basement Membrane; Creatine; Cryptococcosis; D

1971
[Clinical and morphological studies in nephrotic syndrome. Report on 83 children].
    Monatsschrift fur Kinderheilkunde, 1972, Volume: 120, Issue:1

    Topics: Azathioprine; Biopsy; Child; Child, Preschool; Cortisone; Cyclophosphamide; Female; Fluorescent Anti

1972
Azathioprine in glomerulonephritis. A long-term study.
    Lancet (London, England), 1972, May-20, Volume: 1, Issue:7760

    Topics: Adolescent; Azathioprine; Basement Membrane; Child; Chronic Disease; Follow-Up Studies; Glomerular F

1972
Clinicopathological study of nephrotic syndrome in childhood.
    Lancet (London, England), 1970, Jun-27, Volume: 1, Issue:7661

    Topics: Adolescent; Age Factors; Azathioprine; Beta-Globulins; Biopsy; Child; Child, Preschool; Cyclophospha

1970
Lupus nephritis: response to azathioprine.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:8

    Topics: Adolescent; Azathioprine; Edema; Female; Glomerular Filtration Rate; Glomerulonephritis; Hematuria;

1974
Schönlein-Henoch nephritis.
    The Quarterly journal of medicine, 1972, Volume: 41, Issue:163

    Topics: Adolescent; Adrenal Cortex Hormones; Azathioprine; Biopsy; Child; Child, Preschool; Cyclophosphamide

1972
Renal transplantation in patients with carcinoma.
    British medical journal, 1974, Oct-19, Volume: 4, Issue:5937

    Topics: Adult; Angiography; Azathioprine; Cadaver; Female; Graft Rejection; Hematuria; Humans; Immunosuppres

1974
[Results of immunosuppressive therapy in chronic nephropathy with special reference to biopsy findings].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1972, Nov-15, Volume: 27, Issue:22

    Topics: Azathioprine; Biopsy; Chronic Disease; Cyclophosphamide; Glomerulonephritis; Hematuria; Humans; Immu

1972
Lupus nephritis: clinical course in relation to treatment.
    Perspectives in nephrology and hypertension, 1973, Volume: 1 Pt 2, Issue:0

    Topics: Adolescent; Adult; Aged; Azathioprine; Child; Creatinine; Cyclophosphamide; Female; Follow-Up Studie

1973
The idiopathic nephrotic syndrome of childhood. A clinical reevaluation of 148 cases.
    American journal of diseases of children (1960), 1974, Volume: 127, Issue:6

    Topics: Adolescent; Antistreptolysin; Azathioprine; Bacteriuria; Blood Urea Nitrogen; Child; Child, Preschoo

1974
[Treatment of primary proliferative glomerulonephritis by azathioprine].
    Journal d'urologie et de nephrologie, 1968, Volume: 74, Issue:12

    Topics: Adolescent; Adult; Azathioprine; Female; Fluorescent Antibody Technique; Glomerular Filtration Rate;

1968
Multiple renal abscesses in a patient with rapidly progressive glomerulonephritis while on immunosuppressive treatment.
    Scandinavian journal of urology and nephrology, 1971, Volume: 5, Issue:3

    Topics: Abscess; Adult; Ampicillin; Azathioprine; Creatinine; Escherichia coli; Female; Glomerulonephritis;

1971
[Long term treatment of chronic glomerulonephritis, clinical course and results of renal biopsies].
    Archiv fur klinische Medizin, 1969, Volume: 216, Issue:4

    Topics: Acetates; Adolescent; Adult; Azathioprine; Biopsy; Blood Pressure; Chloroquine; Female; Glomerulonep

1969
[Experiences in administration of antimetabolites in treatment of dermatomyosis].
    Dermatologische Monatschrift, 1972, Volume: 158, Issue:7

    Topics: Adrenal Cortex Hormones; Adult; Aged; Antimetabolites; Azathioprine; Dermatomyositis; Female; Follow

1972
[Etiology and therapy of idiopathic lung hemosideroses].
    Helvetica medica acta. Supplementum, 1966, May-15, Volume: 46

    Topics: Adult; Azathioprine; Cortisone; Female; Hematuria; Hemosiderosis; Humans; Iron; Lung Diseases; Pulmo

1966
Delayed healing process and exacerbation of a diffuse intra- and extracapillary glomerulonephritis with IgA-deposits (clinical, light-, electron- and immunofluorescent-microscopic examinations of sequential biopsies).
    Virchows Archiv. A, Pathology. Pathologische Anatomie, 1971, Volume: 354, Issue:4

    Topics: Anti-Bacterial Agents; Azathioprine; Biopsy; Capillaries; Cell Nucleus; Child; Epithelial Cells; Fib

1971
[Treatment of chronic glomerulonephritis with imuran].
    Schweizerische medizinische Wochenschrift, 1970, Dec-05, Volume: 100, Issue:49

    Topics: Adolescent; Adult; Aged; Azathioprine; Biopsy; Blood Sedimentation; Child; Chronic Disease; Colic; D

1970
[Familial nephrotic syndrome].
    Monatsschrift fur Kinderheilkunde, 1970, Volume: 118, Issue:6

    Topics: Acute Kidney Injury; Adolescent; Adrenal Cortex Hormones; Age Factors; Azathioprine; Biopsy; Child;

1970