Page last updated: 2024-10-23

azathioprine and Hematologic Malignancies

azathioprine has been researched along with Hematologic Malignancies in 3 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Research Excerpts

ExcerptRelevanceReference
" Chronic immunosuppression is a known risk factor for various malignancies, and azathioprine in particular has been reported in association with solid and hematologic malignancies, including diffuse large B-cell lymphoma."8.31Primary hepatic Epstein-Barr virus-positive diffuse large B-cell lymphoma associated with azathioprine immunosuppression: a case report. ( Marell, PS; Shi, M; Wingo, MT, 2023)
" Chronic immunosuppression is a known risk factor for various malignancies, and azathioprine in particular has been reported in association with solid and hematologic malignancies, including diffuse large B-cell lymphoma."4.31Primary hepatic Epstein-Barr virus-positive diffuse large B-cell lymphoma associated with azathioprine immunosuppression: a case report. ( Marell, PS; Shi, M; Wingo, MT, 2023)
"The frequency of cancer-associated mortality was 11% that was 2% of the total lupus population."1.33[The occurrence of malignancies in a Hungarian lupus population]. ( Kiss, E; Szegedi, G; Szekanecz, E; Tarr, T; Zeher, M, 2006)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Marell, PS1
Shi, M1
Wingo, MT1
Kari, JA1
Trompeter, RS1
Tarr, T1
Szekanecz, E1
Zeher, M1
Szegedi, G1
Kiss, E1

Reviews

1 review available for azathioprine and Hematologic Malignancies

ArticleYear
What is the calcineurin inhibitor of choice for pediatric renal transplantation?
    Pediatric transplantation, 2004, Volume: 8, Issue:5

    Topics: Azathioprine; Calcineurin Inhibitors; Child; Clinical Trials as Topic; Cyclosporine; Growth and Deve

2004

Other Studies

2 other studies available for azathioprine and Hematologic Malignancies

ArticleYear
Primary hepatic Epstein-Barr virus-positive diffuse large B-cell lymphoma associated with azathioprine immunosuppression: a case report.
    Journal of medical case reports, 2023, May-02, Volume: 17, Issue:1

    Topics: Azathioprine; Epstein-Barr Virus Infections; Female; Hematologic Neoplasms; Herpesvirus 4, Human; Hu

2023
[The occurrence of malignancies in a Hungarian lupus population].
    Orvosi hetilap, 2006, Nov-19, Volume: 147, Issue:46

    Topics: Adult; Aged; Azathioprine; Breast Neoplasms; Bronchial Neoplasms; Cyclophosphamide; Female; Gastroin

2006