Page last updated: 2024-10-23

azathioprine and Heart Defects, Congenital

azathioprine has been researched along with Heart Defects, Congenital in 11 studies

Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.

Heart Defects, Congenital: Developmental abnormalities involving structures of the heart. These defects are present at birth but may be discovered later in life.

Research Excerpts

ExcerptRelevanceReference
"Graft coronary disease was found in 8 patients (11%), 2 were re-transplanted and have survived 4."1.33Ten year survival after paediatric heart transplantation: a single centre experience. ( Khaghani, A; Smith, RR; Wray, J; Yacoub, M, 2005)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19904 (36.36)18.7374
1990's3 (27.27)18.2507
2000's3 (27.27)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Stiefelhagen, P1
Gamba, A1
Merlo, M1
Fiocchi, R1
Terzi, A1
Mammana, C1
Sebastiani, R1
Ferrazzi, P1
Smith, RR1
Wray, J1
Khaghani, A1
Yacoub, M1
Jamieson, SW1
Baldwin, J1
Stinson, EB1
Reitz, BA2
Oyer, PE1
Hunt, S1
Billingham, M1
Theodore, J1
Modry, D1
Bieber, CP1
Bridges, ND1
Mallory, GB1
Huddleston, CB1
Canter, CE1
Spray, TL1
Parisi, F1
Abbattista, AD1
Squitieri, C1
Vinciguerra, G1
La Vigna, G1
Di Donato, R1
Catena, G1
Shaddy, RE1
Lambert, LM1
Fuller, TC1
Profaizer, T1
Thompson, DD1
Baker, SI1
Osborne, KA1
Hawkins, JA1
Chiavarelli, M1
Boucek, MM1
Nehlsen-Cannarella, SL1
Gundry, SR1
Razzouk, AJ1
Bailey, LL1
Baumgartner, WA1
Augustine, S1
Borkon, AM1
Gardner, TJ1
Lower, RR1
Hurley, RM1
Drummond, KN1

Reviews

1 review available for azathioprine and Heart Defects, Congenital

ArticleYear
Current status of clinical cardiac transplantation.
    Transplantation proceedings, 1974, Volume: 6, Issue:4 Suppl 1

    Topics: Adult; Arteriosclerosis; Azathioprine; B-Lymphocytes; Brain Death; Cardiac Catheterization; Cardiomy

1974

Trials

1 trial available for azathioprine and Heart Defects, Congenital

ArticleYear
Prospective randomized trial of azathioprine in cryopreserved valved allografts in children.
    The Annals of thoracic surgery, 2001, Volume: 71, Issue:1

    Topics: Adolescent; Antibody Formation; Aortic Valve; Azathioprine; Child; Child, Preschool; Cryopreservatio

2001

Other Studies

9 other studies available for azathioprine and Heart Defects, Congenital

ArticleYear
[Sudden fever attacks in a young Crohn disease patient. Would you have considered the heart here?].
    MMW Fortschritte der Medizin, 2014, Nov-20, Volume: 156, Issue:20

    Topics: Adult; Aortic Valve; Azathioprine; Bicuspid Aortic Valve Disease; Crohn Disease; Diagnosis, Differen

2014
Heart transplantation in patients with previous Fontan operations.
    The Journal of thoracic and cardiovascular surgery, 2004, Volume: 127, Issue:2

    Topics: Adolescent; Adult; Azathioprine; Biomarkers; Blood Proteins; Cardiac Output, Low; Child; Child, Pres

2004
Ten year survival after paediatric heart transplantation: a single centre experience.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2005, Volume: 27, Issue:5

    Topics: Azathioprine; Cardiomyopathies; Child; Child, Preschool; Coronary Angiography; Coronary Disease; Cyc

2005
Clinical heart-lung transplantation.
    Transplantation, 1984, Volume: 37, Issue:1

    Topics: Adult; Azathioprine; Cyclosporins; Female; Graft Rejection; Heart; Heart Defects, Congenital; Heart

1984
Lung transplantation in infancy and early childhood.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1996, Volume: 15, Issue:9

    Topics: Actuarial Analysis; Azathioprine; Cause of Death; Cyclosporine; Graft Rejection; Heart Defects, Cong

1996
Twelve years of cyclosporine in pediatric heart transplantation: what is the future?
    Transplantation proceedings, 1998, Volume: 30, Issue:5

    Topics: Adolescent; Azathioprine; Cardiomyopathies; Child; Child, Preschool; Cyclosporine; Drug Therapy, Com

1998
Neonatal cardiac transplantation. Intermediate-term results and incidence of rejection. Loma Linda University Pediatric Heart Transplant Group.
    Archives of surgery (Chicago, Ill. : 1960), 1992, Volume: 127, Issue:9

    Topics: Azathioprine; Cause of Death; Confidence Intervals; Cyclosporine; Female; Follow-Up Studies; Graft R

1992
Present expectations in cardiac transplantation.
    The Annals of thoracic surgery, 1987, Volume: 43, Issue:6

    Topics: Adolescent; Adult; Azathioprine; Cardiomyopathies; Child; Child, Preschool; Coronary Disease; Cyclos

1987
Glomerular enlargement in primary renal disease: a quantitative study.
    Archives of pathology, 1974, Volume: 97, Issue:6

    Topics: Adolescent; Adult; Age Factors; Aging; Autopsy; Azathioprine; Biopsy; Child; Child, Preschool; Cyclo

1974