azathioprine has been researched along with Hearing Loss, Sensorineural in 14 studies
Azathioprine: An immunosuppressive agent used in combination with cyclophosphamide and hydroxychloroquine in the treatment of rheumatoid arthritis. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), this substance has been listed as a known carcinogen. (Merck Index, 11th ed)
azathioprine : A thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS.
Hearing Loss, Sensorineural: Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dosage was further reduced by adding methotrexate at 7." | 7.01 | Relapsing autoimmune inner ear disease with significant response to methotrexate and azathioprine combination therapy: A case report and mini literature review. ( Huang, KH; Lin, CD; Lin, HC; Wu, PC, 2023) |
| "Sclerosing sialadenitis occurred before AIP, whereas autoimmune sensorineural hearing loss, allergic purpura and endocapillary proliferative glomerulonephritis occurred after AIP." | 5.35 | Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy. ( Ando, T; Hayashi, K; Joh, T; Miyabe, K; Naitoh, I; Nakazawa, T; Ohara, H; Okumura, F; Sano, H; Takahashi, S; Tanaka, H; Yoshida, M, 2009) |
| " The dosage was further reduced by adding methotrexate at 7." | 3.01 | Relapsing autoimmune inner ear disease with significant response to methotrexate and azathioprine combination therapy: A case report and mini literature review. ( Huang, KH; Lin, CD; Lin, HC; Wu, PC, 2023) |
| "Atypical Cogan's syndrome is more commonly associated with systemic manifestations than typical disease, and may be refractory to immunosuppressive treatment." | 2.45 | Cogan's syndrome: present and future directions. ( Harney, S; Molloy, M; Murphy, G; Shanahan, F; Sullivan, MO, 2009) |
| "Sensorineural hearing loss has been described in autoimmune disorders but is rare." | 2.44 | Sensorineural hearing loss in systemic lupus erythematosus: case report and literature review. ( Khalidi, NA; Rebello, R; Robertson, DD, 2008) |
| " The administration of intratympanic infliximab is an effective and safe technique." | 1.56 | Intratympanic infliximab is a safe and effective rescue therapy for refractory immune-mediated hearing loss. ( García-Fernández, A; Mata-Castro, N; Sanz-López, L; Varillas-Delgado, D, 2020) |
| "Sensorineural hearing loss is significantly more prevalent in refractory rheumatoid arthritis patients." | 1.46 | Hearing status in patients with rheumatoid arthritis. ( Ahmadzadeh, A; Amini, E; Daneshi, A; Daraei, M; Jalessi, M; Peyvandi, AA; Ranjbar, LA, 2017) |
| " Systemic treatment usually begins with high dosage corticosteroids." | 1.42 | Atypical Cogan's syndrome: a case report and summary of current treatment options. ( Jančatová, D; Komínek, P; Matoušek, P; Zeleník, K, 2015) |
| "Sclerosing sialadenitis occurred before AIP, whereas autoimmune sensorineural hearing loss, allergic purpura and endocapillary proliferative glomerulonephritis occurred after AIP." | 1.35 | Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy. ( Ando, T; Hayashi, K; Joh, T; Miyabe, K; Naitoh, I; Nakazawa, T; Ohara, H; Okumura, F; Sano, H; Takahashi, S; Tanaka, H; Yoshida, M, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 6 (42.86) | 29.6817 |
| 2010's | 5 (35.71) | 24.3611 |
| 2020's | 2 (14.29) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, KH | 1 |
| Lin, HC | 1 |
| Lin, CD | 1 |
| Wu, PC | 1 |
| Mata-Castro, N | 1 |
| Sanz-López, L | 1 |
| Varillas-Delgado, D | 1 |
| García-Fernández, A | 1 |
| Ahmadzadeh, A | 1 |
| Daraei, M | 1 |
| Jalessi, M | 1 |
| Peyvandi, AA | 1 |
| Amini, E | 1 |
| Ranjbar, LA | 1 |
| Daneshi, A | 1 |
| Bloom, JL | 1 |
| Lin, C | 1 |
| Imundo, L | 1 |
| Guthery, S | 1 |
| Stepenaskie, S | 1 |
| Galambos, C | 1 |
| Lowichik, A | 1 |
| Bohnsack, JF | 1 |
| Jenkinson, PW | 1 |
| Syed, MI | 1 |
| Mcclymont, L | 1 |
| Jančatová, D | 1 |
| Zeleník, K | 1 |
| Komínek, P | 1 |
| Matoušek, P | 1 |
| Postelmans, L | 1 |
| Willermain, F | 1 |
| Guillaume, MP | 1 |
| Libert, M | 1 |
| Hermanus, N | 1 |
| Vannechel, C | 1 |
| Verougstraete, C | 1 |
| Murphy, G | 1 |
| Sullivan, MO | 1 |
| Shanahan, F | 1 |
| Harney, S | 1 |
| Molloy, M | 1 |
| Naitoh, I | 1 |
| Nakazawa, T | 1 |
| Ohara, H | 1 |
| Sano, H | 1 |
| Ando, T | 1 |
| Hayashi, K | 1 |
| Tanaka, H | 1 |
| Okumura, F | 1 |
| Miyabe, K | 1 |
| Yoshida, M | 1 |
| Takahashi, S | 1 |
| Joh, T | 1 |
| McCarthy, EM | 1 |
| Cunnane, G | 1 |
| Broughton, SS | 1 |
| Meyerhoff, WE | 1 |
| Cohen, SB | 1 |
| Khalidi, NA | 1 |
| Rebello, R | 1 |
| Robertson, DD | 1 |
| Lasak, JM | 1 |
| Sataloff, RT | 1 |
| Hawkshaw, M | 1 |
| Carey, TE | 1 |
| Lyons, KM | 1 |
| Spiegel, JR | 1 |
| Benitez, JT | 1 |
| Arsenault, MD | 1 |
| Licht, JM | 1 |
| Cohen, SD | 1 |
| Greenberg, RV | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Trial of Rilonacept for Treatment of Autoimmune Neurosensory Hearing Loss[NCT02828033] | Early Phase 1 | 10 participants (Anticipated) | Interventional | 2017-02-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for azathioprine and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Relapsing autoimmune inner ear disease with significant response to methotrexate and azathioprine combination therapy: A case report and mini literature review.
Topics: Adrenal Cortex Hormones; Adult; Autoimmune Diseases; Azathioprine; Female; Hearing Loss, Sensorineur | 2023 |
Cogan's syndrome: present and future directions.
Topics: Adrenal Cortex Hormones; Adult; Azathioprine; Dose-Response Relationship, Drug; Fatal Outcome; Femal | 2009 |
Sensorineural hearing loss in systemic lupus erythematosus: case report and literature review.
Topics: Adult; Anticoagulants; Antimetabolites; Audiometry, Pure-Tone; Azathioprine; Drug Therapy, Combinati | 2008 |
11 other studies available for azathioprine and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Intratympanic infliximab is a safe and effective rescue therapy for refractory immune-mediated hearing loss.
Topics: Administration, Oral; Adult; Aged; Auditory Threshold; Azathioprine; Chronic Disease; Female; Hearin | 2020 |
Hearing status in patients with rheumatoid arthritis.
Topics: Acoustic Impedance Tests; Adult; Arthritis, Rheumatoid; Audiometry, Pure-Tone; Azathioprine; Cochlea | 2017 |
H syndrome: 5 new cases from the United States with novel features and responses to therapy.
Topics: Adult; Antibodies, Monoclonal, Humanized; Azathioprine; Child; Child, Preschool; Contracture; Diagno | 2017 |
Progressive, reversible sensorineural hearing loss caused by azathioprine.
Topics: Audiometry, Pure-Tone; Azathioprine; Female; Hearing Loss, Sensorineural; Humans; Middle Aged | 2014 |
Atypical Cogan's syndrome: a case report and summary of current treatment options.
Topics: Adolescent; Azathioprine; Cogan Syndrome; Female; Glucocorticoids; Hearing Loss, Bilateral; Hearing | 2015 |
Retinal arterio-arterial collaterals in SUSAC syndrome.
Topics: Adult; Azathioprine; Brain; Cerebrovascular Disorders; Collateral Circulation; Corpus Callosum; Cycl | 2008 |
Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy.
Topics: Adrenal Cortex Hormones; Autoimmune Diseases; Azathioprine; Drug Therapy, Combination; Female; Heari | 2009 |
Treatment of relapsing polychondritis in the era of biological agents.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Aortic Valve; | 2010 |
Immune-mediated inner ear disease: 10-year experience.
Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathioprine; Cyclopho | 2004 |
Autoimmune inner ear disease: steroid and cytotoxic drug therapy.
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Autoimmune Diseases; Azathiopri | 2001 |
Evidence of central vestibulo-auditory dysfunction in atypical Cogan's syndrome: a case report.
Topics: Adult; Audiometry; Auditory Diseases, Central; Azathioprine; Drug Therapy, Combination; Electronysta | 1990 |